keyword
https://read.qxmd.com/read/38530993/impact-of-war-on-hiv-related-healthcare-services-and-health-workers-in-eastern-ukraine-a-qualitative-study
#21
JOURNAL ARTICLE
Alla Barsukova, Maria Shvab, Nancy H Puttkammer, Olga Vitruk, Alyona P Ihnatiuk, Larisa I Hetman, Misti R McDowell, Pamela Y Collins, Anna Y Shapoval
The 2022 Russian invasion of Ukraine has caused serious challenges for healthcare workers (HCWs) and HIV-related healthcare services. This study assessed the effects of the invasion on HCWs wellbeing and on continuity of HIV services, using in-depth interviews with HCWs from facilities offering HIV antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP) services in the Donetsk region of Eastern Ukraine. A directed content analysis, with both inductive and deductive approaches, was conducted. Ten HCWs (6 [60%] doctors, 4 [40%] nurses; 9 [90%] female) were interviewed...
March 26, 2024: AIDS Care
https://read.qxmd.com/read/38530987/analysis-of-10-year-income-trends-for-pharmacists-and-other-select-health-professionals
#22
JOURNAL ARTICLE
Marie A Chisholm-Burns, Christina A Spivey
DISCLAIMER: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. PURPOSE: To evaluate income trends among pharmacists and other select health professions (dentists, nurse practitioners, registered nurses, and physicians) in the US for the 10-year period of 2012 to 2021, with special attention given to the first 2 years of the COVID-19 pandemic (2020 and 2021)...
March 26, 2024: American Journal of Health-system Pharmacy: AJHP
https://read.qxmd.com/read/38530876/considerations-of-gender-affirming-care-for-transgender-and-gender-diverse-youth
#23
JOURNAL ARTICLE
Alex R Mills, Kevin N Astle, Kelsea Gallegos Aragon
In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time.
March 26, 2024: American Journal of Health-system Pharmacy: AJHP
https://read.qxmd.com/read/38530790/implementation-of-a-pharmacy-technician-career-ladder-and-pharmacy-technician-training-program
#24
JOURNAL ARTICLE
Lisa Thames, Corry Johnston, Julie Cash, Martina Holder, Alissa Voils
DISCLAIMER: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. PURPOSE: To describe the implementation of a pharmacy technician career ladder and internal technician training program at UF Health Shands Hospital in Gainesville, Florida...
March 26, 2024: American Journal of Health-system Pharmacy: AJHP
https://read.qxmd.com/read/38530778/graphpath-a-graph-attention-model-for-molecular-stratification-with-interpretability-based-on-the-pathway-pathway-interaction-network
#25
JOURNAL ARTICLE
Teng Ma, Jianxin Wang
MOTIVATION: Studying the molecular heterogeneity of cancer is essential for achieving personalized therapy. At the same time, understanding the biological processes that drive cancer development can lead to the identification of valuable therapeutic targets. Therefore, achieving accurate and interpretable clinical predictions requires paramount attention to thoroughly characterizing patients at both the molecular and biological pathway levels. RESULTS: Here, we present GraphPath, a biological knowledge-driven graph neural network with multi-head self-attention mechanism that implements the pathway-pathway interaction network...
March 26, 2024: Bioinformatics
https://read.qxmd.com/read/38530649/iatrogenic-hyperchloremia-an-overview-in-hospitalized-patients-for-pharmacists
#26
JOURNAL ARTICLE
Amoreena Most, Sarah Nordbeck, Nicholas Farina
DISCLAIMER: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. PURPOSE: The purpose of this therapeutic update is to provide pharmacists with a general overview of the pathophysiology of hyperchloremia and describe strategies to help prevent development of this electrolyte abnormality in hospitalized patients...
March 26, 2024: American Journal of Health-system Pharmacy: AJHP
https://read.qxmd.com/read/38530598/challenges-in-obtaining-and-seeking-information-among-breast-cancer-survivors-in-an-asian-country-a-qualitative-study
#27
JOURNAL ARTICLE
Izzati Yussof, Noraida Mohamed Shah, Nur Fa'izah Ab Muin, Sarahfarina Abd Rahim, Ernieda Hatah, Nor Asyikin Mohd Tahir, Kavinash Loganathan, Murallitharan Munisamy
Breast cancer survivors on adjuvant endocrine therapy (AET) have distinct information-seeking experience compared to those in the diagnosis and intensive treatment phase. This study aimed to understand the challenges in obtaining and seeking information among Malaysian breast cancer survivors. We conducted semi-structured, one-to-one interviews among patients using AET from two hospitals and a local cancer organization. Interviews were conducted until theme saturation was achieved (N = 25). Interviews were de-identified, transcribed verbatim, and analysed using thematic analysis...
March 26, 2024: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://read.qxmd.com/read/38530288/publication-of-pharmacy-resident-research-projects-a-systematic-review-and-meta-analysis
#28
JOURNAL ARTICLE
Michael L Behal, Paige E Fields, Aaron M Cook, Rebecca J Morgan, Alexander H Flannery
DISCLAIMER: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. PURPOSE: Pharmacy residents often aspire to develop research skills through conducting a research project...
March 26, 2024: American Journal of Health-system Pharmacy: AJHP
https://read.qxmd.com/read/38529950/european-practices-on-antithrombotic-management-during-percutaneous-mechanical-circulatory-support-in-adults-a-survey-of-the-association-for-acute-cardiovascular-care-acvc-of-the-esc-and-the-european-branch-of-the-extracorporeal-life-support-organization-euroelso
#29
JOURNAL ARTICLE
Charlotte J Van Edom, Justyna Swol, Thomas Castelein, Mario Gramegna, Kurt Huber, Sergio Leonardi, Thomas Mueller, Federico Pappalardo, Susanna Price, Hannah Schaubroeck, Benedikt Schrage, Guido Tavazzi, Leen Vercaemst, Pascal Vranckx, Christophe Vandenbriele
BACKGROUND: Bleeding and thrombotic complications compromise outcomes in patients undergoing percutaneous mechanical circulatory support (pMCS) with veno-arterial extracorporeal membrane oxygenation (V-A ECMO) and/or microaxial flow pumps like the Impella™. Antithrombotic practices are an important determinant of the coagulopathic risk, but standardization in the antithrombotic management during pMCS is lacking. This survey outlines European practices in antithrombotic management in adults on pMCS, making an initial effort to standardize practices, inform future trials, and enhance outcomes...
March 26, 2024: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/38528707/psychological-support-needs-for-children-with-food-allergy-and-their-families-a-systematic-review
#30
REVIEW
Rebecca C Knibb, Christina J Jones, Linda J Herbert, Cassandra Screti
This systematic review aimed to review the evidence for psychological support for children with food allergies and their families, identify effective psychological interventions, and highlight the support needs for this group. A systematic search was undertaken across six databases (up to October 2023). Articles were checked by three reviewers for inclusion. Study data were extracted, and quality was assessed using the Mixed Methods Appraisal Tool. A narrative synthesis was undertaken. A total of 11 papers were included (n = 838 participants)...
March 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38528640/anxiety-in-turner-syndrome-engaging-community-to-address-barriers-and-facilitators-to-diagnosis-and-care
#31
JOURNAL ARTICLE
Alexandra Carl, Marybel Good, Erica Haag, Christa Hutaff-Lee, Deanna Swain, Nicole Tartaglia, Casey Sakamoto, Shanlee Davis, Talia Thompson
Turner syndrome (TS), caused by complete or partial loss of the second sex chromosome, is associated with complex medical manifestations. The TS community identifies anxiety as a major contributor to reduced quality of life. The study aimed to improve understanding of anxiety symptomatology, diagnosis, and care in individuals with TS. A mixed methods design integrated community engagement, including community leaders as co-investigators and a community advisory board, an online survey (N = 135), and in-depth interviews (N = 10)...
March 25, 2024: American Journal of Medical Genetics. Part A
https://read.qxmd.com/read/38528605/coordinated-activation-of-dnmt3a-and-tet2-in-cancer-stem-cell-like-cells-initiates-and-sustains-drug-resistance-in-hepatocellular-carcinoma
#32
JOURNAL ARTICLE
Tao Cheng, Changli Zhou, Sicheng Bian, Kelsey Sobeck, Yahui Liu
BACKGROUND: Resistance to targeted therapies represents a significant hurdle to successfully treating hepatocellular carcinoma (HCC). While epigenetic abnormalities are critical determinants of HCC relapse and therapeutic resistance, the underlying mechanisms are poorly understood. We aimed to address whether and how dysregulated epigenetic regulators have regulatory and functional communications in establishing and maintaining drug resistance. METHODS: HCC-resistant cells were characterized by CCK-8, IncuCyte Live-Cell analysis, flow cytometry and wound-healing assays...
March 25, 2024: Cancer Cell International
https://read.qxmd.com/read/38528321/acknowledging-religion-in-cognitive-behavioural-therapy-the-effect-on-alliance-treatment-expectations-and-credibility-in-a-video-vignette-study
#33
JOURNAL ARTICLE
Hibah Hassan, Sarah Lack, Paul M Salkovskis, Graham R Thew
OBJECTIVES: Developing mental health services which are accessible and acceptable to those from minority backgrounds continues to be a priority. In the United Kingdom, individuals who identify with a religion are underrepresented in Talking Therapies services as compared to those with no religion. This necessitates an understanding of how therapy is perceived. This online study explored the impact of explicitly acknowledging religion on anticipated alliance, treatment credibility and expectations of therapy in a non-clinical sample of British Muslims...
March 25, 2024: British Journal of Clinical Psychology
https://read.qxmd.com/read/38527421/evaluation-of-a-pharmacist-led-workflow-for-the-fda-expanded-access-program
#34
JOURNAL ARTICLE
Blake T Barta, Ann McGee, Beth Mc Lendon Arvik, Tyler A Vest
DISCLAIMER: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. PURPOSE: This project aimed to characterize the resources necessary for pharmacists to support the required steps for obtaining and handling investigational drugs outside of a study protocol in the individual patient and intermediate-size population Expanded Access Program (EAP) processes...
March 25, 2024: American Journal of Health-system Pharmacy: AJHP
https://read.qxmd.com/read/38527294/comprehensive-workflow-evaluation-to-improve-medication-distribution-to-the-emergency-department-in-an-academic-medical-center
#35
JOURNAL ARTICLE
Melanie J Mills, Alec Martschenko, Keven Gomez, Madison L Hooker, Charlotte Pastoor, Tyler A Vest
DISCLAIMER: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. PURPOSE: The fast-paced environment of the emergency department (ED), with frequent admissions, discharges, and transfers, poses a challenge for pharmacy departments to effectively distribute and store medications...
March 25, 2024: American Journal of Health-system Pharmacy: AJHP
https://read.qxmd.com/read/38527076/parenteral-nutrition-at-home-long-term-parenteral-nutrition
#36
JOURNAL ARTICLE
Vanessa J Kumpf, Brenda Gray, Jessica Monczka, Sarah Zeraschi, Stanislaw Klek
DISCLAIMER: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. PURPOSE: Some diseases require that patients receive parenteral nutrition (PN) over a prolonged time period...
March 25, 2024: American Journal of Health-system Pharmacy: AJHP
https://read.qxmd.com/read/38526836/the-need-for-the-great-%C3%A2-score-to-predict-relapse-in-graves-disease-a-questionnaire-among-patients-and-internal-medicine-specialists
#37
JOURNAL ARTICLE
H I Jansen, C Heuveling van Beek, P H Bisschop, A C Heijboer, E Bruinstroop, A Boelen
PURPOSE: Graves' disease (GD) is an auto-immune cause of hyperthyroidism. First-line treatment often consists of a 12-18 month course of antithyroid drugs (ATD). After discontinuation of ATD, GD relapses in approximately 50% of patients. The 'Graves recurrent event after therapy+ ' (GREAT+) score may predict individual relapse chances after ATD discontinuation more accurately based on clinical and laboratory parameters at diagnosis. We investigated the need for the GREAT+ score through an online questionnaire among GD patients and physicians treating GD...
March 25, 2024: Journal of Endocrinological Investigation
https://read.qxmd.com/read/38526543/use-of-lcp-tacrolimus-lcpt-in-kidney-transplantation-a-delphi-consensus-survey-of-expert-clinicians
#38
JOURNAL ARTICLE
Alexander Wiseman, Tarek Alhamad, Rita R Alloway, Beatrice P Concepcion, Matthew Cooper, Richard Formica, Christina L Klein, Vineeta Kumar, Nicolae Leca, Fuad Shihab, David J Taber, Sarah Mulnick, Donald M Bushnell, Monica Hadi, Suphamai Bunnapradist
BACKGROUND LCPT (Envarsus XR®) is a common once-daily, extended-release oral tacrolimus formulation used in kidney transplantation. However, there are minimal evidence-based recommendations regarding optimal dosing and treatment in the de novo and conversion settings. MATERIAL AND METHODS Using Delphi methodology, 12 kidney transplantation experts with LCPT experience reviewed available data to determine potential consensus topics. Key statements regarding LCPT use were generated and disseminated to the panel in an online Delphi survey...
March 12, 2024: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://read.qxmd.com/read/38525921/the-impact-of-a-prophylactic-skin-dressing-on-surface-guided-patient-positioning-in-chest-wall-radiation-therapy
#39
JOURNAL ARTICLE
James Cumming, Kenton Thompson, Katrina Woodford, Vanessa Panettieri, Daniel Sapkaroski
INTRODUCTION: Surface-guided radiation therapy (SGRT) has emerged as a powerful tool to improve patient setup accuracy in radiation therapy (RT). Combined with the goal of increasing RT accuracy is an ongoing effort to decrease RT side effects. The application of a prophylactic skin dressing to the treatment site is a well-documented method of reducing skin-related side effects from RT. This paper aims to investigate whether the application of Mepitel, a prophylactic skin dressing, has an impact on the accuracy of surface-guided patient setups in chest wall RT...
March 25, 2024: Journal of Medical Radiation Sciences
https://read.qxmd.com/read/38525889/an-evaluation-of-survive-and-thrive-a-10-week-group-psychoeducational-course-for-adult-interpersonal-trauma-survivors-in-scotland
#40
JOURNAL ARTICLE
Frederick O'Donald, Elise Gunter, Ailie Castle, Rachel Warner, Fhionna Moore
Emerging evidence supports a phased approach to trauma treatment, including manualised group-based interventions, to facilitate symptom reduction resulting from complex trauma sequelae. This study investigates the efficacy of Survive and Thrive , a 10-week group psychoeducational course for adult survivors of interpersonal trauma. Between August 2019 and February 2022, participants were enrolled on the course. The Clinical Outcomes in Routine Evaluation-Outcome Measure (CORE-OM) and Difficulties in Emotion Regulation Scale-Short Form (DERS-SF) were administered pre-intervention and immediately post-intervention...
March 25, 2024: Cognitive Behaviour Therapy
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