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https://www.readbyqxmd.com/read/29780345/addiction-like-mobile-phone-behavior-validation-and-association-with-problem-gambling
#1
Andreas Fransson, Mariano Chóliz, Anders Håkansson
Mobile phone use and its potential addiction has become a point of interest within the research community. The aim of the study was to translate and validate the Test of Mobile Dependence (TMD), and to investigate if there are any associations between mobile phone use and problem gambling. This was a cross-sectional study on a Swedish general population. A questionnaire consisting of a translated version of the TMD, three problem gambling questions (NODS-CLiP) together with two questions concerning previous addiction treatment was published online...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29734827/behavioral-addictions-as-mental-disorders-to-be-or-not-to-be
#2
Nancy M Petry, Kristyn Zajac, Meredith K Ginley
Should excessive and problematic engagement in nonsubstance use behaviors be mental disorders? The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) repositioned gambling disorder in the substance use disorders section and introduced Internet gaming disorder in the research appendix; the International Classification of Diseases (ICD-11) is also considering it. This article outlines pros and cons of considering behavioral addictions as mental disorders and also reviews the DSM-5 decision-making processes...
May 7, 2018: Annual Review of Clinical Psychology
https://www.readbyqxmd.com/read/29704596/locomotor-sensitization-to-cocaine-in-adolescent-and-adult-female-wistar-rats
#3
Sydney A Rowson, Stephanie L Foster, David Weinshenker, Gretchen N Neigh
Adolescent stress exposure is a risk factor for drug abuse, and sex differences contribute to psychostimulant responses. Although many studies have utilized the Wistar rat strain in adolescent stress paradigms, the impact of adolescent stress exposure on addiction-like outcomes has not been rigorously tested in female Wistar rats. In this study, locomotor sensitization was assessed in adolescent and adult female Wistar rats following either chronic stress during adolescence (CAS) or no stress (NS). Adolescent, but not adult, female Wistar rats developed locomotor sensitization to 15 mg/kg cocaine over 5 days of treatment, regardless of stress history...
April 25, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29689260/effects-of-monoamines-on-the-intrinsic-excitability-of-lateral-orbitofrontal-cortex-neurons-in-alcohol-dependent-and-non-dependent-female-mice
#4
Sudarat Nimitvilai, Marcelo F Lopez, John J Woodward
Changes in brain reward and control systems of frontal cortical areas including the orbitofrontal cortex (OFC) are associated with alcohol use disorders (AUD). The OFC is extensively innervated by monoamines, and drugs that target monoamine receptors have been used to treat a number of neuropsychiatric diseases, including AUDs. Recent findings from this laboratory demonstrate that D2, α2-adrenergic and 5HT1A receptors all decrease the intrinsic excitability of lateral OFC (lOFC) neurons in naïve male mice and that this effect is lost in mice exposed to repeated cycles of chronic intermittent ethanol (CIE) vapor...
April 21, 2018: Neuropharmacology
https://www.readbyqxmd.com/read/29672167/sex-differences-in-opioid-use-and-medical-issues-during-buprenorphine-naloxone-treatment
#5
Celestina Barbosa-Leiker, Sterling McPherson, Matthew E Layton, Ekaterina Burduli, John M Roll, Walter Ling
BACKGROUND: There are sex differences in buprenorphine/naloxone clinical trials for opioid use. While women have fewer opioid-positive urine samples, relative to men, a significant decrease in opioid-positive samples was found during treatment for men, but not women. In order to inform sex-based approaches to improve treatment outcomes, research is needed to determine if opioid use, and predictors of opioid use, differs between men and women during treatment. OBJECTIVES: To test for sex differences in opioid use during a buprenorphine/naloxone clinical trial and determine if sex differences exist in the associations between addiction-related problem areas and opioid use over the course of the trial...
April 19, 2018: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/29626743/examining-racial-ethnic-differences-in-patterns-of-benzodiazepine-prescription-and-misuse
#6
Benjamin Cook, Timothy Creedon, Ye Wang, Chunling Lu, Nicholas Carson, Piter Jules, Esther Lee, Margarita Alegría
BACKGROUND: Benzodiazepines (BZDs) are widely prescribed during psychiatric treatment. Unfortunately, their misuse has led to recent surges in overdose emergency visits and drug-related deaths. METHODS: Electronic health record data from a large healthcare system were used to describe racial/ethnic, sex, and age differences in BZD use and dependence. Among patients with a BZD prescription, we assessed differences in the likelihood of subsequently receiving a BZD dependence diagnosis, number of BZD prescriptions, receiving only one BZD prescription, and receiving 18 or more BZD prescriptions...
March 26, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29560944/-an-essential-negative-effect-of-a-family-history-of-substance-use-on-readiness-for-drug-dependence-rehabilitation-treatment-in-inpatients-with-addictions
#7
A O Kibitov, L P Babicheva, N A Chuprova, A V Shchurina, R A Romashkin
AIM: To reveal objective factors predicting the readiness of inpatient drug treatment patients to undergo a rehabilitation program. MATERIAL AND METHODS: In a retrospective comparative study, drug-dependent individuals (n=199, 16.6% females, 83.4% men, 91.5% opioid-dependent) were studied. After conducting motivational activities based on cognitive-behavioral psychotherapy, the premorbid, anamnestic, clinical, socio-demographic characteristics of patients were studied as possible predictors of readiness for rehabilitation using binary logistic regression...
2018: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/29484686/predictors-of-gabapentin-overuse-with-or-without-concomitant-opioids-in-a-commercially-insured-u-s-population
#8
Alyssa M Peckham, Kirk E Evoy, Jordan R Covvey, Leslie Ochs, Kathleen A Fairman, David A Sclar
OBJECTIVE: Research suggests the medical consequences of gabapentin overuse depend on whether gabapentin is abused alone or with opioids to potentiate an opioid "high." The objective of this study was to assess predictors of gabapentin overuse with or without concomitant opioids. METHODS: Data were obtained from the Truven Health MarketScan® Commercial Claims and Encounters database for 2013 through 2015. Eligibility criteria were gabapentin utilization, with or without opioids, for 120 days or longer throughout a 12-month observation period...
April 2018: Pharmacotherapy
https://www.readbyqxmd.com/read/29478874/memory-focused-cognitive-therapy-for-cocaine-use-disorder-theory-procedures-and-preliminary-evidence-from-an-external-pilot-randomised-controlled-trial
#9
John Marsden, Camille Goetz, Tim Meynen, Luke Mitcheson, Garry Stillwell, Brian Eastwood, John Strang, Nick Grey
BACKGROUND: Cocaine use disorder (CUD) is a debilitating condition with no NICE-recommended medication or specific psychosocial interventions. In the United Kingdom (UK), general counselling (treatment-as-usual; TAU) is widely delivered, but has limited effectiveness. We tested the feasibility, safety and preliminary efficacy of a novel, adjunctive psychosocial intervention for CUD, called 'memory-focused cognitive therapy' (MFCT). METHODS: We did a two-arm, external pilot randomised controlled trial at a specialist community National Health Service addictions clinic in London, UK...
March 2018: EBioMedicine
https://www.readbyqxmd.com/read/29433454/hepatitis-b-c-in-the-countries-of-the-eu-eea-a-systematic-review-of-the-prevalence-among-at-risk-groups
#10
REVIEW
Abby May Falla, Sanne Henrietta Ina Hofstraat, Erika Duffell, Susan Josien Maria Hahné, Lara Tavoschi, Irene Karen Veldhuijzen
BACKGROUND: In 2016, the World Health Organisation set a goal to eliminate viral hepatitis by 2030. Robust epidemiological information underpins all efforts to achieve elimination and this systematic review provides estimates of HBsAg and anti-HCV prevalence in the European Union/European Economic Area (EU/EEA) among three at-risk populations: people in prison, men who have sex with men (MSM), and people who inject drugs (PWID). METHODS: Estimates of the prevalence among the three risk groups included in our study were derived from multiple sources...
February 12, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29396749/neuroticism-magnifies-the-detrimental-association-between-social-media-addiction-symptoms-and-wellbeing-in-women-but-not-in-men-a-three-way-moderation-model
#11
Ofir Turel, Natalie Tasha Poppa, Oren Gil-Or
Addiction symptoms in relation to the use of social networking sites (SNS) can be associated with reduced wellbeing. However, the mechanisms that can control this association have not been fully characterized, despite their relevance to effective treatment of individuals presenting SNS addiction symptoms. In this study we hypothesize that sex and neuroticism, which are important determinants of how people evaluate and respond to addiction symptoms, moderate this association. To examine these assertions, we employed hierarchical linear and logistic regression techniques to analyze data collected with a cross-sectional survey of 215 Israeli college students who use SNS...
February 3, 2018: Psychiatric Quarterly
https://www.readbyqxmd.com/read/29382494/-clinical-epidemiological-study-in-children-with-cleft-lip-palate-in-a-secondary-level-hospital
#12
Alicia Pons-Bonals, Leticia Pons-Bonals, Sandra Margarita Hidalgo-Martínez, Carlos Francisco Sosa-Ferreyra
BACKGROUND: One of the most common congenital disorders that affects the facial structures is the cleft lip palate (CLP). The aim of this study was to generate the clinical-epidemiological profile of CLP patients from Hospital de Especialidades del Niño y la Mujer (HENM) Dr. Felipe Nuñez Lara, from the Ministry of Health, Queretaro, Mexico, from 2011 to 2014, who received treatment from the Cleft Lip Palate Clinic in order to provide interdisciplinary treatments for CLP patients based on the information from the pediatric records...
March 2017: Boletín Médico del Hospital Infantil de México
https://www.readbyqxmd.com/read/29368436/do-women-with-complex-alcohol-and-other-drug-use-histories-want-women-only-residential-treatment
#13
Joanne Neale, Charlotte N E Tompkins, Alison D Marshall, Carla Treloar, John Strang
BACKGROUND: Women-only addiction services tend to be provided on a poorly evidenced assumption that women want single-sex treatment. We draw upon women's expectations and experiences of women-only residential rehabilitation to stimulate debate on this issue. METHODS: Semi-structured interviews were undertaken with 19 women aged 25-44 years [currently in treatment (n = 9), successfully completed treatment (n = 5), left treatment prematurely (n = 5)]. All had histories of physical or sexual abuse, and relapses linked to relationships with men...
January 24, 2018: Addiction
https://www.readbyqxmd.com/read/29341869/a-report-of-the-24th-annual-congress-on-women-s-health-workshop-on-transforming-women-s-health-from-research-to-practice
#14
Jennifer L Plank-Bazinet, Annie Sampson, Susan G Kornstein, Gregory G Germino, Marjorie Robert-Guroff, Stephen E Gilman, Cora Lee Wetherington, Nakela Cook, Terri L Cornelison, Lisa Begg, Janine Austin Clayton
Sex and gender are critical contributors to overall health and disease, and considering both in research informs the development of prevention strategies and treatment interventions for both men and women. The National Institutes of Health (NIH) Office of Research on Women's Health sponsored a preconference workshop on this topic at the 24th Annual Women's Health Congress, which was held in Crystal City, VA, in April 2016. The workshop featured presentations by NIH intramural and extramural scientists who presented data on a variety of topics including polycystic kidney disease, vaccine protection, depression, drug addiction, and cardiovascular disease...
January 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29339170/sub-anesthetic-doses-of-ketamine-attenuate-nicotine-self-administration-in-rats
#15
Amir H Rezvani, Yousef Tizabi, Susan Slade, Bruk Getachew, Edward D Levin
Smoking cessation strategies are of prime medical importance. Despite availability of various pharmacological agents in combating addiction to nicotine, more effective medications are needed. Based on recent findings, the glutamatergic system in the brain may provide novel targets. Here, we evaluated the effects of acute administration of sub-anesthetic doses of ketamine, an NMDA receptor antagonist, in both male and female Sprague-Dawley rats trained to self-administer nicotine. Animals were injected subcutaneously with 5, 7...
March 6, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29295020/disclosing-sex-trading-histories-to-providers-barriers-and-facilitators-to-navigation-of-social-services-among-women-impacted-by-commercial-sexual-exploitation
#16
Lara Gerassi, Tonya E Edmond, Vanessa Fabbre, Abby Howard, Andrea J Nichols
Sex trafficking and commercial sexual exploitation (CSE) can lead to devastating health and mental health consequences for women, such as elevated rates of substance use, trauma, posttraumatic stress disorder, depression, sexually transmitted infections (STIs), and HIV. Consequently, engagement with services that address addiction, mental health, and housing, and provide general advocacy is critically important to women's increased safety, stabilization, and quality of life. The purpose of this study is to identify perceived barriers and facilitators to service access and engagement with social services among women involved in CSE...
December 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29248905/primary-addictive-substances-used-among-patients-treated-in-a-hospital-based-addiction-medicine-service
#17
Daniel Feingold, Shaul Lev-Ran
INTRODUCTION: This study sought to explore the differences in primary addictive substances used among individuals referred to an ambulatory hospital-based addiction service in Israel according to sex, age and source of referral. METHOD: Data were drawn from all referral forms received during a two-year period (N=140). Categories of primary addictive substances included alcohol, drugs (cannabis, synthetic cannabinoids, illicit stimulants and heroin) and medications (prescription opioids, prescription stimulants and benzodiazepines)...
2017: Israel Journal of Psychiatry and related Sciences
https://www.readbyqxmd.com/read/29247973/excess-mortality-in-children-born-to-opioid-addicted-parents-a-national-register-study-in-taiwan
#18
Shao-You Fang, Nicole Huang, Jen-Huoy Tsay, Su-Hui Chang, Chuan-Yu Chen
BACKGROUND: Young offspring of individuals with opioid use disorders have great exposure to a wide array of social disadvantages and stressors. This study aimed to investigate excess mortality before the age of six and predictors of premature death in children born to opioid-involved parents. METHODS: A total of 3210 children born between 2004 and 2009 to parents with opioid use disorders (roughly a quarter of whom were born after parental methadone treatment enrollment) were identified in Taiwan...
February 1, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29227676/studying-sex-differences-in-animal-models-of-addiction-an-emphasis-on-alcohol-related-behaviors
#19
Elisa R Hilderbrand, Amy W Lasek
Animal models are essential for understanding the biological factors that contribute to drug and alcohol addiction and discovering new pharmacotherapies to treat these disorders. Alcohol (ethanol) is the most commonly abused drug in the world, and as the prevalence of alcohol use disorder (AUD) increases, so does the need for effective pharmacotherapies. In particular, treatments with high efficacy in the growing number of female AUD sufferers are needed. Female animals remain underrepresented in biomedical research and sex differences in the brain's response to alcohol are poorly understood...
December 26, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/29223761/chemsex-risk-behaviours-and-sexually-transmitted-infections-among-men-who-have-sex-with-men-in-dublin-ireland
#20
Ronan W Glynn, Niamh Byrne, Siobhan O'Dea, Adam Shanley, Mary Codd, Eamon Keenan, Mary Ward, Derval Igoe, Susan Clarke
BACKGROUND: Drug use for or during sex ('chemsex') among MSM has caused concern, because of the direct effects of the drugs themselves, and because of an increased risk of transmission of sexually transmitted infections (STIs). This study aimed to assess the prevalence of chemsex, associated behaviours and STIs among attendees at Ireland's only MSM-specific sexual health clinic in Dublin over a six week period in 2016. METHODS: The questionnaire collected demographic data, information on sexuality and sexual practice, self-reported history of treatment for STIs, and chemsex use...
February 2018: International Journal on Drug Policy
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