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https://www.readbyqxmd.com/read/28628620/prevalence-and-determinants-of-online-sex-use-in-the-german-population
#1
Manfred E Beutel, Sebastian Giralt, Klaus Wölfling, Yve Stöbel-Richter, Claudia Subic-Wrana, Iris Reiner, Ana Nanette Tibubos, Elmar Brähler
INTRODUCTION: The unlimited access to sexual features in the World Wide Web has raised concerns about excessive and problematic online-sex use. However, little is known about antecedents of internet-sex use of different intensity. Based on a representative German sample of 2,522 participants between the ages of 14 and 97 years, the aims of the present study were (1) to determine the prevalence rates of online-sex users with the short version (ISSTGSV) of the Internet Sex Screening Test and (2) to associate online-sex use with anxious vs...
2017: PloS One
https://www.readbyqxmd.com/read/28624586/modeling-the-development-of-drug-addiction-in-male-and-female-animals
#2
REVIEW
Wendy J Lynch
An increasing emphasis has been placed on the development and use of animal models of addiction that capture defining features of human drug addiction, including escalation/binge drug use, enhanced motivation for the drug, preference for the drug over other reward options, use despite negative consequences, and enhanced drug-seeking/relapse vulnerability. The need to examine behavior in both males and females has also become apparent given evidence demonstrating that the addiction process occurs differently in males and females...
June 14, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/28600000/sex-specific-effects-of-developmental-alcohol-exposure-on-cocaine-induced-place-preference-in-adulthood
#3
Victoria A Macht, Sandra J Kelly, Justin T Gass
Fetal Alcohol Syndrome (FAS) is associated with high rates of drug addiction in adulthood. One possible basis for increased drug use in this population is altered sensitivity to drug-associated contexts. This experiment utilized a rat model of FASD to examine behavioral and neural changes in the processing of drug cues in adulthood. Alcohol was given by intragastric intubation to pregnant rats throughout gestation and to rat pups during the early postnatal period (ET group). Controls consisted of a non-treated group (NC) and a pair-fed group given the intubation procedure without alcohol (IC)...
June 6, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28587607/design-of-a-syndemic-based-intervention-to-facilitate-care-for-men-who-have-sex-with-men-with-high-risk-behaviour-the-syn-bas-in-randomized-controlled-trial
#4
Roel C A Achterbergh, Jannie J van der Helm, Wim van den Brink, Henry J C de Vries
BACKGROUND: Men who have sex with men (MSM) constitute a risk group for sexual transmitted infections (STIs), including HIV. Despite counselling interventions, risk behaviour remains high. Syndemic theory holds that psychosocial problems often co-occur, interact and mutually reinforce each other, thereby increasing high risk behaviours and co-occurring diseases. Therefore, if co-occurring psychosocial problems were assessed and treated simultaneously, this might decrease high risk behaviour and disease...
June 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28586701/the-extent-of-and-factors-associated-with-self-reported-overdose-and-self-reported-receipt-of-naloxone-among-people-who-inject-drugs-pwid-in-england-wales-and-northern-ireland
#5
Charlotte O'Halloran, Katelyn Cullen, Jaquelyn Njoroge, Lucy Jessop, Josie Smith, Vivian Hope, Fortune Ncube
BACKGROUND: Overdose is a major cause of death among PWID, and for opioid overdoses naloxone administration can reduce harm. However, globally there is limited national level data on the extent of non-fatal overdose and naloxone uptake. The first national level data on the extent of self-reported overdose and self-reported receipt of naloxone among UK PWID, providing a baseline to monitor the impact of the recent policy change regarding naloxone availability, is presented. METHODS: Data on self-reported overdose and receipt of naloxone during the preceding year for 2013-2014 from a national survey of PWID was analysed...
June 3, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28570773/integrated-care-pathway-for-co-occurring-major-depressive-and-alcohol-use-disorders-outcomes-of-the-first-two-years
#6
Andriy V Samokhvalov, Saima Awan, Tony P George, Julie Irving, Bernard Le Foll, Steve Perrotta, Charlotte Probst, Peter Voore, Jürgen Rehm
BACKGROUND: Major Depressive Disorder (MDD) and Alcohol Use Disorder (AUD) are highly prevalent, comorbid, and have significant impact on morbidity, mortality, and socioeconomic burden in Canada. Combined psycho- and pharmacotherapies for both conditions promise better outcomes than treatment as usual (TAU). At the Centre for Addiction and Mental Health, Toronto, Canada, we developed and implemented an Integrated Care Pathway (ICP) specifically for treatment of concurrent MDD and AUD...
June 1, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28513227/temporal-relationship-of-sex-risk-behaviors-and-substance-use-severity-among-men-in-substance-use-treatment
#7
Howard Newville, James L Sorensen, Mary Hatch-Maillette, Donald A Calsyn
Sex risk behaviors and substance use are intertwined. Many men continue to engage in high-risk sexual behaviors even when enrolled in substance use disorder (SUD) treatment. We hypothesized that changes in sex risk behaviors would coincide with changes in drug/alcohol use severity among men in SUD treatment. During an HIV risk-reduction trial, men in methadone maintenance and outpatient drug-free treatment (N = 359) completed assessments at baseline and six months after. We assessed changes in sex risk and substance use severity, using the Addiction Severity Index-Lite (ASI-Lite), controlling for treatment condition...
May 17, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/28503193/correlates-comorbidities-and-suicidal-tendencies-of-problematic-game-use-in-a-national-wide-sample-of-korean-adults
#8
Subin Park, Hong Jin Jeon, Jung Woo Son, Haesoo Kim, Jin Pyo Hong
BACKGROUND: This study aimed to investigate the prevalence, correlates, comorbidities, and suicidal tendencies of problematic game use in a nationally representative sample of Korean adults. METHODS: Of the 6022 subjects who participated in the 2011 Korean Epidemiologic Catchment Area study and completed the Composite International Diagnostic Interview 2.1, 1397 game users were evaluated for problematic game use using 9-item DSM-5 proposed criteria for Internet gaming disorder...
2017: International Journal of Mental Health Systems
https://www.readbyqxmd.com/read/28448903/violence-trauma-and-living-with-hiv-longitudinal-predictors-of-initiating-crystal-methamphetamine-injection-among-sex-workers
#9
Elena Argento, Steffanie A Strathdee, Shira Goldenberg, Melissa Braschel, Julio Montaner, Kate Shannon
BACKGROUND: Despite rapid increases in crystal methamphetamine (CM) use worldwide and established gendered patterns of use, empirical research on CM injection initiation among sex workers is limited. Given the wide range of harms associated with CM, alongside stimulant effects including sexual dis-inhibition and prolonged awake-ness, this study aimed to longitudinally investigate socio-structural predictors of initiating CM injection among sex workers in Vancouver, Canada. METHODS: Data (2010-2014) were drawn from a community-based cohort of women sex workers: AESHA (An Evaluation of Sex Workers Health Access)...
April 19, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28379107/gender-and-sex-trading-among-active-methamphetamine-users-in-cape-town-south-africa
#10
Ryan R Lion, Melissa H Watt, Wendee M Wechsberg, Christina S Meade
BACKGROUND: South Africa has experienced a tremendous rise in methamphetamine use since the year 2000. Sex trading is a global phenomenon that has been observed in active drug users and has been associated with risks for HIV infection and violence. OBJECTIVES: This paper describes and examines the correlates of sex trading among active methamphetamine users in Cape Town, South Africa. METHODS: Through peer referral, 360 (201 male; 159 female) active methamphetamine users were recruited in a peri-urban township...
May 12, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28367308/association-between-cannabis-use-and-methadone-maintenance-treatment-outcomes-an-investigation-into-sex-differences
#11
Laura Zielinski, Meha Bhatt, Nitika Sanger, Carolyn Plater, Andrew Worster, Michael Varenbut, Jeff Daiter, Guillaume Pare, David C Marsh, Dipika Desai, James MacKillop, Meir Steiner, Stephanie McDermid Vaz, Lehana Thabane, Zainab Samaan
BACKGROUND: Cannabis will soon become legalized in Canada, and it is currently unclear how this will impact public health. Methadone maintenance treatment (MMT) is the most common pharmacological treatment for opioid use disorder (OUD), and despite its documented effectiveness, a large number of patients respond poorly and experience relapse to illicit opioids. Some studies implicate cannabis use as a risk factor for poor MMT response. Although it is well established that substance-use behaviors differ by sex, few of these studies have considered sex as a potential moderator...
2017: Biology of Sex Differences
https://www.readbyqxmd.com/read/28360785/determination-of-clinical-and-socio-demographical-differences-of-adolescents-applying-to-a-treatment-center-with-family-encouragement-or-the-decision-of-the-probation-office-and-determination-of-predictive-factors-in-maintaining-soberness-among-probation-cases
#12
Zeki Yüncü, Rezzan Aydin, Cahide Aydin, Burcu Özbaran, Sezen Köse
INTRODUCTION: This study has two objectives. The first objective of this study was the determination of some basic clinical and socio-demographical differences among the adolescents with substance abuse who apply to a treatment center with support from their family or by order of the probation office. The other objective of this study was the determination of the predictive factors in maintaining soberness among adolescents who successfully complete the probation treatment process. METHODS: The target population of this study is young adults under 19 years of age who apply to a substance addiction center for adolescents as a result of encouragement from their family or ordered by the Probation Office between 2005 and 2013...
June 2016: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/28347350/the-association-between-age-of-onset-of-opioid-use-and-comorbidity-among-opioid-dependent-patients-receiving-methadone-maintenance-therapy
#13
Leen Naji, Brittany Burns Dennis, Monica Bawor, Michael Varenbut, Jeff Daiter, Carolyn Plater, Guillaume Pare, David C Marsh, Andrew Worster, Dipika Desai, James MacKillop, Lehana Thabane, Zainab Samaan
BACKGROUND: Opioid use disorder (OUD) affects approximately 21.9 million people worldwide. This study aims to determine the association between age of onset of opioid use and comorbid disorders, both physical and psychiatric, in patients receiving methadone maintenance treatment (MMT) for OUD. Understanding this association may inform clinical practice about important prognostic factors of patients on MMT, enabling clinicians to identify high-risk patients. METHODS: This study includes data collected between June 2011 and August 2016 for the Genetics of Opioid Addiction research collaborative between McMaster University and the Canadian Addiction Treatment Centers...
March 28, 2017: Addiction Science & Clinical Practice
https://www.readbyqxmd.com/read/28296573/the-adverse-effects-and-treatment-results-of-smoking-cessation-pharmacotherapy-during-fasting-non-fasting-state
#14
Sinem Iliaz, Seda Tural Onur, Mehmet Atilla Uysal, Efsun Gonca Uğur Chousein, Elif Tanriverdi, Belma Akbaba Bagci, Ayse Bahadir, Didem Gorgun Hattatoglu, Mediha Gonenc Ortakoylu, Sibel Yurt
BACKGROUND: Cigarette smoking is one of the most common addictions worldwide. Muslim smokers reduce the number of cigarettes they smoke during Ramadan due to the long fasting hours. OBJECTIVES: We aimed to share our experience in a smoking cessation clinic during Ramadan by analyzing the efficacy and adverse effects of once-daily dosing of bupropion or varenicline in a fasting group compared with conventional dosing in a non-fasting group. METHODS: We analyzed 57 patients who attended our smoking cessation clinic during Ramadan of 2014 and 2015, and at least one follow-up visit...
March 15, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28265716/don-t-stress-about-crf-assessing-the-translational-failures-of-crf1antagonists
#15
REVIEW
Samantha R Spierling, Eric P Zorrilla
BACKGROUND: Dr. Athina Markou sought treatments for a common neural substrate shared by depression and drug dependence. Antagonists of corticotropin-releasing factor (CRF) receptors, a target of interest to her, have not reached the clinic despite strong preclinical rationale and sustained translational efforts. METHODS: We explore potential causes for the failure of CRF1 antagonists and review recent findings concerning CRF-CRF1 systems in psychopathology. RESULTS: Potential causes for negative outcomes include (1) poor safety and efficacy of initial drug candidates due to bad pharmacokinetic and physicochemical properties, (2) specificity problems with preclinical screens, (3) the acute nature of screens vs...
May 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28224962/-gambling-in-elderly-patients
#16
Morgane Guillou Landreat, Jean-Yves Le Reste, Catherine Théréné-Mouden, Julie Caillon, Jennyfer Cholet, Marie Grall Bronnec
Behavioural addictions concern behaviour which generate pleasure (shopping, gambling, sex, etc.). Pathological gambling is the most common behavioural addiction in elderly people. It can be severely harmful causing psychological, financial and family problems and increasing the risk of suicide. Gambling addiction is underestimated in the elderly. Psychological, social and family support is important whatever the age, with treatment aiming to improve the person's quality of life, help them regain control of their gambling or stop altogether...
January 2017: Soins. Gérontologie
https://www.readbyqxmd.com/read/28215999/rat-animal-models-for-screening-medications-to-treat-alcohol-use-disorders
#17
REVIEW
Richard L Bell, Sheketha R Hauser, Tiebing Liang, Youssef Sari, Antoniette Maldonado-Devincci, Zachary A Rodd
The purpose of this review is to present animal research models that can be used to screen and/or repurpose medications for the treatment of alcohol abuse and dependence. The focus will be on rats and in particular selectively bred rats. Brief introductions discuss various aspects of the clinical picture, which provide characteristics of individuals with alcohol use disorders (AUDs) to model in animals. Following this, multiple selectively bred rat lines will be described and evaluated in the context of animal models used to screen medications to treat AUDs...
February 16, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28179811/sex-differences-in-addiction
#18
Jill B Becker
Women exhibit more rapid escalation from casual drug taking to addiction, exhibit a greater withdrawal response with abstinence, and tend to exhibit greater vulnerability than men in terms of treatment outcome. In rodents, short-term estradiol intake in female rats enhances acquisition and escalation of drug taking, motivation for drugs of abuse, and relapse-like behaviors. There is also a sex difference in the dopamine response in the nucleus accumbens. Ovariectomized female rats exhibit a smaller initial dopamine increase after cocaine treatment than castrated males...
December 2016: Dialogues in Clinical Neuroscience
https://www.readbyqxmd.com/read/28166486/drinking-motives-of-adult-patients-seeking-treatment-for-problematic-alcohol-use
#19
Anders Hammarberg, Caisa Öster, Christina Nehlin
INTRODUCTION: The Drinking Motives Questionnaire (DMQ) measures motives for alcohol consumption on four subscales. Coping with negative affect and enhancement of positive affect have been shown to be associated with high levels of alcohol consumption and alcohol-related problems. Few studies exist concerning drinking motives among treatment-seeking patients. The aims of the study were to investigate the factor structure of the shortened form of the revised DMQ (DMQ-R SF), map main drinking, explore group differences in motives due to sex, age, level of drinking problems and symptoms of depression/anxiety and to investigate whether different drinking motives predict alcohol-related problems in this group...
February 6, 2017: Journal of Addictive Diseases
https://www.readbyqxmd.com/read/28127624/oxycodone-self-administration-in-male-and-female-rats
#20
Maria Mavrikaki, Marco Pravetoni, Sarah Page, David Potter, Elena Chartoff
RATIONALE: Oxycodone is one of the most widely prescribed painkillers in the USA. However, its use is complicated by high abuse potential. As sex differences have been described in drug addiction, the present study tested for sex differences in intravenous oxycodone self-administration in rats. METHODS: Male and female Sprague-Dawley rats were implanted with jugular vein catheters and trained to self-administer oxycodone (0.03 mg/kg/infusion) under fixed ratio 1 (FR1), FR2, and FR5 schedules of reinforcement followed by a dose-response study to assess sensitivity to the reinforcing effects of oxycodone...
January 27, 2017: Psychopharmacology
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