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https://www.readbyqxmd.com/read/27888650/closure-of-the-cervical-os-in-patients-after-fertility-preserving-treatment-for-early-cervical-cancer-results-of-a-prospective-observational-study
#1
Mandy Mangler, Malgorzata Lanowska, Anne Bartens, Aaron Schindler, Jens-Uwe Blohmer, Dorothee Speiser
INTRODUCTION: Up to 50% of the infants delivered after radical vaginal trachelectomy (RVT) are born prematurely. An effective strategy to reduce this number could be the closure of the cervical os (CCO). PATIENTS AND METHODS: Fifteen pregnant patients who had a RVT due to early cervical cancer were included in this prospective case control study. All patients were scheduled for CCO early in the second trimester. CCO was performed in 12 patients. Their data were compared to data from 125 pregnancies after a RVT without CCO...
November 26, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27831834/role-of-imaging-in-fertility-sparing-treatment-of-gynecologic-malignancies
#2
Andrea G Rockall, Mahrukh Qureshi, Ioanna Papadopoulou, Srdjan Saso, Nicholas Butterfield, Isabelle Thomassin-Naggara, Alan Farthing, J Richard Smith, Nishat Bharwani
Treatments for gynecologic cancer usually result in loss of fertility due to surgery or radical radiation therapy in the pelvis. In countries with an established screening program for cervical cancer, the majority of gynecologic malignancies occur in postmenopausal women. However, a substantial number of affected women are of childbearing age and have not completed their families. In these younger women, consideration of fertility preservation may be important. This article describes the fertility-sparing treatment options that are currently available and outlines the role of imaging in the selection of eligible patients on the basis of a review of the literature...
November 2016: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/27804040/oncologic-and-obstetric-outcomes-and-complications-during-pregnancy-after-fertility-sparing-abdominal-trachelectomy-for-cervical-cancer-a-retrospective-review
#3
Kaoru Okugawa, Hiroaki Kobayashi, Kenzo Sonoda, Eisuke Kaneki, Yoshiaki Kawano, Nobuhiro Hidaka, Katsuko Egashira, Yasuyuki Fujita, Hideaki Yahata, Kiyoko Kato
BACKGROUND: Trachelectomy was developed as a fertility-sparing surgery for early-stage cervical cancer in patients of childbearing age. The purpose of this study is to evaluate oncologic and obstetric outcomes and complications after abdominal trachelectomy. METHODS: We began to perform abdominal trachelectomy in 2005. Our institutional review board approved this clinical study, and fully informed consent was obtained from each patient. The medical records of patients who underwent trachelectomy were retrospectively reviewed...
November 1, 2016: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27795832/fertility-sparing-management-in-cervical-cancer-balancing-oncologic-outcomes-with-reproductive-success
#4
REVIEW
Karla Willows, Genevieve Lennox, Allan Covens
BACKGROUND: Cervical cancer is the fourth most common cancer among women worldwide, many of who are still within their reproductive lifespan. Advances in screening and treatment have increased the 5-year survival for early stage disease to over 90 % in developed countries. The focus is now shifting to reducing morbidity and improving fertility outcomes for cervical cancer patients. Radical trachelectomy with lymph node assessment became the standard of care for selected women with lesions <2 cm who desire fertility preservation...
2016: Gynecologic Oncology Research and Practice
https://www.readbyqxmd.com/read/27790635/fertility-sparing-management-of-large-cell-neuroendocrine-tumour-of-cervix-a-case-report-review-of-literature
#5
S Rajkumar, R Iyer, G Culora, G Lane
Large cell neuroendocrine cervical carcinoma (LCNEC) is a rare and aggressive cancer that tends to spread and recur early despite intensive multimodal treatment. Conventional treatment strategies for early stage neuroendocrine tumour (NET) include radical hysterectomy followed by adjuvant chemotherapy. There are only 2 reported cases of fertility sparing treatment for NET. We report on the first case of successful conception and delivery at term following radical trachelectomy for early stage LCNEC.
November 2016: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/27742473/quality-of-life-after-radical-trachelectomy-for-early-stage-cervical-cancer-a-5-year-prospective-evaluation
#6
N D Fleming, P T Ramirez, P T Soliman, K M Schmeler, G B Chisholm, A M Nick, S N Westin, M Frumovitz
OBJECTIVES: To longitudinally assess quality of life (QOL) in women undergoing radical trachelectomy for early-stage cervical cancer. METHODS: We prospectively enrolled patients with stage IA1-IB1 cervical cancer prior to undergoing radical trachelectomy to complete validated QOL instruments. These instruments included the General Health-Related QOL (SF-12), Functional Assessment of Cancer Therapy-Cervix (FACT-Cx), MD Anderson Symptom Inventory (MDASI), Female Sexual Functioning Index (FSFI), and Satisfaction with Decision scale (SWD)...
December 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27679351/risk-factors-for-trachelectomy-following-supracervical-hysterectomy
#7
Z Tsafrir, J Aoun, E Papalekas, L D Schiff, E Theoharis, R Hanna, R Sangha, D Eisenstein
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27679261/reduced-port-size-nerve-sparing-radical-trachelectomy-the-least-invasive-fertility-sparing-radical-surgery
#8
M Andou, A Yamanaka, K Kodama, A Shirane, M Fukuta
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27678850/laparoscopic-isthmocervical-cerclage-with-mersilene-tape-after-radical-vaginal-trachelectomy
#9
G G Gomes-Da-Silveira, S A Pessini, G P Silveira
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27678842/successful-uterine-isthmo-vagina-anastomosis-with-barbed-suture-in-robotic-radical-trachelectomy
#10
E Nam, J Yoon, I Lee, J Lee, S Kim, S Kim, Y Kim
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27678600/laparoscopic-radical-trachelectomy-in-a-young-patient-with-early-cervical-cancer
#11
C-L Lee, K-G Huang, K-Y Wu, C-Y Huang, H-H Kuo
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27678584/robotically-assisted-radical-trachelectomy
#12
M Andou, A Yamanaka, K Kodama, A Shirane, M Fukuta
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27668393/sensitivity-of-follow-up-methods-in-patients-after-fertility-sparing-surgery-for-cervical-cancers
#13
Jiri Slama, Daniela Fischerova, Michal Zikan, Roman Kocian, Anna Germanova, Filip Fruhauf, Ladislav Dusek, David Cibula
OBJECTIVE: The aim of our study was to compare the sensitivity of various methods and their combinations in the follow-up of patients with cervical cancer after fertility-sparing surgery (FSS). METHODS: Included were women with cervical cancer in stages IA2 to IB2 who underwent FSS, which includes pelvic lymphadenectomy, sentinel lymph node biopsy, abdominal radical trachelectomy, vaginal trachelectomy, or needle conization. Follow-up visits were scheduled at 3-month intervals and included symptom-oriented discussion, gynecological and physical examination, colposcopy, Papanicolaou test, human papillomavirus (HPV) DNA test, and ultrasound examination...
September 23, 2016: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27668200/surgical-and-obstetrical-outcomes-after-laparoscopic-radical-trachelectomy-and-pelvic-lymphadenectomy-for-early-cervical-cancer
#14
So-Eun Yoo, Kyeong A So, Seon-Ah Kim, Mi Kyung Kim, Yoo Kyung Lee, In-Ho Lee, Tae-Jin Kim, Ki Heon Lee
OBJECTIVE: The aim of this study was to evaluate the surgical and obstetrical outcomes of patients with early cervical cancer who underwent laparoscopic radical trachelectomy and pelvic lymphadenectomy. METHODS: We analyzed data from women who underwent laparoscopic radical trachelectomy and pelvic lymphadenectomy between July 2000 and October 2014. RESULTS: Of a total of 12 patients, 91.7% were FIGO (International Federation of Gynecology and Obstetrics) stages IA2 and IB1...
September 2016: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/27651696/conservative-surgery-for-early-cervical-cancer
#15
REVIEW
P Rema, Iqbal Ahmed
There is a rising incidence of early cervical cancer in young patients as a result of screening and early detection. Treatment of cervical cancer by surgery or radiotherapy results in permanent infertility which affects the quality of life of cancer survivors. Now with improved survival rates among early cervical cancer patients, conservative surgery aiming at fertility preservation in those desiring future pregnancy is an accepted treatment. Conservative surgery is possible in early cervical cancer including micro invasive cancer and stage IB cancers less than 2 cm...
September 2016: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27643652/vaginal-radical-trachelectomy-for-early-stage-cervical-cancer-increased-recurrence-risk-for-adenocarcinoma
#16
Petra L M Zusterzeel, Fraukje J M Pol, Maaike van Ham, Ronald P Zweemer, Ruud L M Bekkers, Leon F A G Massuger, René H M Verheijen
OBJECTIVE: To evaluate consecutive vaginal radical trachelectomies (VRTs) in early-stage cervical cancer in the 2 main referral centers for fertility-preserving surgery in the Netherlands. MATERIALS AND METHODS: Oncology, fertility, and obstetrical data were recorded in a regional database of all VRTs without neoadjuvant chemotherapy performed in 2 major referral centers between 2000 and 2015. RESULTS: Most of the patients (91.7%) had stage IB1 disease...
September 2016: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27642626/fertility-sparing-surgery-for-the-management-of-young-women-with-embryonal-rhabdomyosarcoma-of-the-cervix-a-case-series
#17
Geneviève Bouchard-Fortier, Raymond H Kim, Lisa Allen, Abha Gupta, Taymaa May
OBJECTIVE: To report three cases of embryonal rhabdomyosarcoma (ERMS) of the cervix in young women successfully treated with fertility-sparing surgery and chemotherapy. METHODS: Between January 2014 and December 2015, three cases of ERMS of the cervix were confirmed in young women at a single tertiary cancer center. All cases were managed by a pediatric oncologist and a gynecologic oncologist with a combination of surgery and chemotherapy. Fertility-sparing surgeries (cervical conization or robotic-assisted radical trachelectomy) were offered to patients depending on the tumor size...
November 2016: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/27610199/simple-trachelectomy-during-pregnancy-for-cervical-cancer
#18
Estefania Moreno-Luna, Patricia Alonso, Javier De Santiago, Ignacio Zapardiel
Invasive cervical cancer is rare during a pregnancy, even though it is one of the most frequently diagnosed neoplasias during that time. It is noted that around 30% of women diagnosed with cervical cancer are of reproductive age. This means that up to 3% of cases of cervical cancer are found in pregnant women or those who are in the post-birth period. A cervicovaginal Pap smear is performed as part of the regular checkup for a pregnant woman during the first visit so that cervical cancer can easily be diagnosed early in these women, detecting it early in up to 70-80% of cases...
2016: Ecancermedicalscience
https://www.readbyqxmd.com/read/27590369/less-radical-surgery-for-early-stage-cervical-cancer-to-what-extent-do-we-justify-it-our-belief
#19
REVIEW
Nikolaos Thomakos, Sofia-Paraskevi Trachana, Miona Davidovic-Grigoraki, Alexandros Rodolakis
Cancer of the uterine cervix, following breast cancer, is the second leading cause of death among gynecological cancers in the developed world. Traditionally, surgical management of early-stage cervical carcinoma is considered as a "sterilizing" procedure, since the uterus is removed. Nowadays, because of the postponement of childbearing to an older age, women younger than 45 years old who are diagnosed with early-stage cervical cancer have a strong desire to preserve fertility. Radical trachelectomy (vaginal or abdominal route) is used for fertility preservation in cases of early-stage (International Federation of Gynecology and Obstetrics Stages IA-IB1) cervical carcinomas with remarkable oncological and obstetrical outcomes...
August 2016: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27578750/fertility-sparing-surgery-for-uterine-cervical-cancer
#20
Seiya Sato, Hiroaki Itamochi, Toru Sugiyama
The standard treatment for early cervical cancer of the uterus (CC) is radical hysterectomy with resection of the parametrium and pelvic lymphadenectomy. At least 40% of patients develop early-stage CC during child-bearing age, therefore preserving the uterus to maintain fertility has been an important consideration. Several surgical procedures including conization and vaginal or abdominal radical trachelectomy have been reported. These procedures are safe for removing lymph node negative CC tumors with <2 cm diameter...
October 2016: Future Oncology
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