Dominic J Romeo, Manisha Banala, Meagan Wu, Jinggang J Ng, Benjamin B Massenburg, Andrew George, Madison DeMarchis, Eric C Liao, Jennifer M Kalish, Jesse A Taylor
OBJECTIVE/ SUMMARY BACKGROUND DATA: We propose the first classification scheme for macroglossia in patients with Beckwith-Wiedemann Syndrome (BWS), the BWS Index of macroGlossia (BIG). METHODS: Patients with molecularly confirmed BWS seen from 2004-2023 were included to develop this system. Relationships among BIG scores, tongue reduction surgery, BWS clinical score, percent mosaicism, and polysomnography findings were examined. RESULTS: Patients were classified from BIG0 to BIG3...
April 22, 2024: Annals of Surgery