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https://www.readbyqxmd.com/read/28102980/microbiology-devices-reclassification-of-influenza-virus-antigen-detection-test-systems-intended-for-use-directly-with-clinical-specimens-final-order
#1
(no author information available yet)
The Food and Drug Administration (FDA) is reclassifying antigen based rapid influenza virus antigen detection test systems intended to detect influenza virus directly from clinical specimens that are currently regulated as influenza virus serological reagents from class I into class II with special controls and into a new device classification regulation.
12, 2017: Federal Register
https://www.readbyqxmd.com/read/28102978/pretreatment-cardiometabolic-status-in-youth-with-early-onset-psychosis-baseline-results-from-the-tea-trial
#2
Karsten G Jensen, Christoph U Correll, Ditte Rudå, Dea G Klauber, Marie Stentebjerg-Olesen, Birgitte Fagerlund, Jens Richardt Møllegaard Jepsen, Anders Fink-Jensen, Anne Katrine Pagsberg
OBJECTIVE: To describe pretreatment cardiometabolic constitution in children and adolescents with first-episode psychosis (FEP). METHODS: Baseline cardiometabolic assessment was performed in youths aged 12-17 years with FEP entering the Tolerability and Efficacy of Antipsychotics (TEA) trial and matched healthy controls. Patients were included between June 10, 2010, and January 29, 2014. ICD-10 was used as the diagnostic classification system. Cardiometabolic risk markers were compared between patients versus controls and antipsychotic-naive versus antipsychotic-exposed patients...
January 17, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28102546/ataluren-and-similar-compounds-specific-therapies-for-premature-termination-codon-class-i-mutations-for-cystic-fibrosis
#3
REVIEW
Aisha A Aslam, Colin Higgins, Ian P Sinha, Kevin W Southern
BACKGROUND: Cystic fibrosis is a common life-shortening genetic disorder in the Caucasian population (less common in other ethnic groups) caused by the mutation of a single gene that codes for the production of the cystic fibrosis transmembrane conductance regulator protein. This protein coordinates the transport of salt (and bicarbonate) across cell surfaces and the mutation most notably affects the airways. In the lungs of people with cystic fibrosis, defective protein results in a dehydrated surface liquid and compromised mucociliary clearance...
January 19, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28102161/orthotopic-autologous-chondrocyte-grafting-as-a-method-of-treatment-of-growth-plate-damage-in-rabbits
#4
Ryszard Tomaszewski, Łukasz Wiktor, Artur Gap
BACKGROUND: With the continuous advances in the therapy of joint cartilage injury, some of those classification systems are also being used for evaluating the quality of regenerating cartilage. Histo lo gi cal assessment of joint cartilage is a very important component in the staging of osteoarthritis and tracing therapeutic outcomes. We performed a histological assessment of regenerating growth plate in a group of New Zealand white rabbits as a component of autologous chondrocyte therapy for growth plate damage...
October 28, 2016: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28101883/mytreehouse-self-concept-assessment-preliminary-psychometric-analysis-of-a-new-self-concept-assessment-for-children-with-cerebral-palsy
#5
Sau Kuan Cheong, Cathryne P Lang, Sheryl A Hemphill, Leanne M Johnston
AIM: To evaluate the preliminary validity and reliability of the myTREEHOUSE Self-Concept Assessment for children with cerebral palsy (CP) aged 8 to 12 years. METHOD: The myTREEHOUSE Self-Concept Assessment includes 26 items divided into eight domains, assessed across three Performance Perspectives (Personal, Social, and Perceived) and an additional Importance Rating. Face and content validity was assessed by semi-structured interviews with seven expert professionals regarding the assessment construct, content, and clinical utility...
January 19, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28101760/a-cad-of-fully-automated-colonic-polyp-detection-for-contrasted-and-non-contrasted-ct-scans
#6
Gökalp Tulum, Bülent Bolat, Onur Osman
PURPOSE: Computer-aided detection (CAD) systems are developed to help radiologists detect colonic polyps over CT scans. It is possible to reduce the detection time and increase the detection accuracy rates by using CAD systems. In this paper, we aimed to develop a fully integrated CAD system for automated detection of polyps that yields a high polyp detection rate with a reasonable number of false positives. METHODS: The proposed CAD system is a multistage implementation whose main components are: automatic colon segmentation, candidate detection, feature extraction and classification...
January 18, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28101655/percutaneous-vertebral-augmentation-in-fragility-fractures-indications-and-limitations
#7
O Gonschorek, S Hauck, T Weiß, V Bühren
INTRODUCTION: There is still no general consensus about the management of osteoporotic vertebral fractures. Recommendations depend on type of fracture, grade of instability, bone quality, and general conditions of the patient. Spontaneous fractures may be considered to be treated different compared to cases with high-velocity trauma. METHODS: According to the DVO, patients without trauma should first be treated conservatively. However, there is no more strict time protocol of 3 or 6 week conservative treatment before operations may be indicated...
January 18, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28101491/can-the-american-thyroid-association-risk-of-recurrence-predict-radioiodine-refractory-disease-in-differentiated-thyroid-cancer
#8
Aamna Hassan, Saima Riaz, Humayun Bashir, M Khalid Nawaz, Raza Hussain
OBJECTIVE: The aim of this study was to compare the TNM staging system and the American Thyroid Association (ATA) recurrence risk classification in predicting radioiodine refractory disease (RRD) in differentiated thyroid cancer (DTC) and to analyze the correlation of stimulated thyroglobulin (Tg) levels and rate of Tg elevation with the standardized uptake value on (18)F-fludeoxyglucose (FDG) PET/CT scan. METHODS: RRD was indicated through the retrospective analysis of consecutive (18)F-FDG PET/CT scans in DTC with stimulated Tg >10 ng/ml and negative (131)I NaI whole-body scans (WBS)...
December 2016: European Thyroid Journal
https://www.readbyqxmd.com/read/28101117/maternal-mortality-ratio-and-causes-of-death-in-iri-between-2009-and-2012
#9
Marzieh Vahiddastjerdy, Nasrin Changizi, Abas Habibollahi, Leila Janani, Zahra Farahani, Farah Babaee
Objective: The Maternal Mortality Ratio is an important health indicator. We presented the distribution and causes of maternal mortality in Islamic Republic of Iran. Materials and methods: After provision of an electronic Registry system for date entry, a descriptive-retrospective data collection had been performed for all maternal Deaths in March 2009- March 2012. All maternal deaths and their demographic characteristic were identified by using medical registries, death certificates, and relevant codes according to International Classification of Diseases (ICD-9) during pregnancy, labor, and 42 days after parturition...
September 2016: Journal of Family & Reproductive Health
https://www.readbyqxmd.com/read/28100066/identification-of-eggs-from-different-production-systems-based-on-hyperspectra-and-cs-svm
#10
J Sun, S Cong, H Mao, X Zhou, X Wu, X Zhang
1. To identify the origin of table eggs more accurately, a method based on hyperspectral imaging technology was studied. 2. The hyperspectral data of 200 samples of intensive and extensive eggs were collected. Standard normalised variables (SNV) combined with Savitzky-Golay (SG) were used to eliminate noise, then stepwise regression (SWR) was used for feature selection. Grid search algorithm (GS), genetic search algorithm (GA), particle swarm optimisation algorithm (PSO) and cuckoo search algorithm (CS) were applied by support vector machine (SVM) to establish a SVM identification model with the optimal parameters...
January 19, 2017: British Poultry Science
https://www.readbyqxmd.com/read/28099735/negative-hpv-testing-among-patients-with-biopsy-proven-cervical-intraepithelial-neoplasia-grade-2-3-or-cervical-cancer
#11
Eduardo González-Bosquet, Sergi Fernandez, Sally Sabra, Jose M Lailla
OBJECTIVE: To determine the proportion of patients diagnosed with cervical cancer or cervical intraepithelial neoplasia grade 2 or 3 (CIN 2/3) despite testing negative for HPV. METHODS: A prospective study was conducted at a university hospital in Barcelona, Spain, between March 2003 and January 2015 among women with abnormal cytology results according to the Bethesda classification system. All participants underwent HPV testing, cytology, and colposcopy. RESULTS: Among 1376 participants, 609 (44...
February 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28099719/evaluating-vaginal-delivery-rates-after-previous-cesarean-delivery-using-the-robson-10-group-classification-system-at-a-tertiary-center-in-brazil
#12
Jose P S Guida, Rodolfo C Pacagnella, Maria L Costa, Elton C Ferreira, Jose G Cecatti
No abstract text is available yet for this article.
December 10, 2016: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28099666/access-to-medicines-in-brazil-based-on-monetary-and-non-monetary-acquisition-data-obtained-from-the-2008-2009-household-budget-survey
#13
Fernanda Caroline Silva Goes, Mauricio Homem-de-Mello, Eloisa Dutra Caldas
OBJECTIVE: To investigate the access to medicines by Brazilian families by monetary and non-monetary acquisition data. METHODS: This is a cross-sectional study based on data obtained from the 2008/2009 Brazilian Household Budget Survey. The units of assessment were households that participated in the survey and the data on the acquisition of medicines over the 30 days prior to the interviews. The medicines were classified according to the Anatomical Therapeutic Chemical classification system...
December 22, 2016: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28099405/insights-in-transplanting-complex-paediatric-renal-recipients-with-vascular-anomalies
#14
Pankaj Chandak, Nicos Kessaris, Chris J Callaghan, Francis Calder, Jelena Stojanovic, Jonathon Olsburgh, Martin Drage, Helen Hume-Smith, Zubir Ahmed, Anna Adamusiak, Derek Roebuck, Colin Forman, Stephen D Marks, Nizam Mamode
BACKGROUND: Children with end-stage kidney disease may have co-existing iatrogenic or congenital vascular anomalies making transplantation difficult. We describe our approach in 5 recipients with vascular anomalies and significant co-morbidities, including one case of blood group incompatibility. METHODS: Five children aged 3 - 17 (median 7) years, weighing 14 - 34 (median 18) kg of whom 4 had occluded inferior vena cava or iliac veins and 2 had previous complex vascular reconstructions prior to transplantation for mid-aortic syndrome and multiple aortic aneurysms, respectively underwent renal transplantation...
January 17, 2017: Transplantation
https://www.readbyqxmd.com/read/28099353/a-predictive-model-to-estimate-the-pretest-probability-of-metastasis-in-patients-with-osteosarcoma
#15
Sisheng Wang, Shaoluan Zheng, Kongzu Hu, Heyan Sun, Jinling Zhang, Genxiang Rong, Jie Gao, Nan Ding, Binjie Gui
Osteosarcomas (OSs) represent a huge challenge to improve the overall survival, especially in metastatic patients. Increasing evidence indicates that both tumor-associated elements but also on host-associated elements are under a remarkable effect on the prognosis of cancer patients, especially systemic inflammatory response. By analyzing a series prognosis of factors, including age, gender, primary tumor size, tumor location, tumor grade, and histological classification, monocyte ratio, and NLR ratio, a clinical predictive model was established by using stepwise logistic regression involved circulating leukocyte to compute the estimated probabilities of metastases for OS patients...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28099350/retrospective-observational-study-comparing-the-international-hip-dysplasia-institute-classification-with-the-tonnis-classification-of-developmental-dysplasia-of-the-hip
#16
Mingyuan Miao, Haiqing Cai, Liwei Hu, Zhigang Wang
The Tonnis radiographic classification of developmental dysplasia of the hip (DDH) has been widely used. The International Hip Dysplasia Institute (IHDI) classification, a new classification system recently developed by the IHDI, is beginning to be applied to evaluate DDH with the absence of an ossification center. This study aimed to validate its reliability in evaluating DDH with an ossification center and compared the 2 classifications in evaluating all DDH hips. In addition, the prediction values of the 2 classifications on clinical management selection were compared...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28099276/factors-in-the-efficacy-safety-and-impact-on-quality-of-life-for-treatment-of-drooling-with-botulinum-toxin-type-a-in-patients-with-cerebral-palsy
#17
Maria D Gonzalez-L, Carmen Martinez, Inma Bori Y Fortuny, Santiago Suso-Vergara
OBJECTIVE: To assess the efficacy and safety of botulinum toxin A (BoNT-A) injected in both submandibular and parotid versus only in parotid glands as a treatment for drooling in patients with spastic and dyskinetic cerebral palsy (CP), including an assessment of impact on quality of life (QoL) based on items from the International Classification of Functioning, Disability, and Health (ICF) core set. DESIGN: Forty patients with CP 18 years or older (mean, 21.8 years) participated in a prospective, single-center, randomized controlled interventional study...
February 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28099116/determination-of-glucose-6-phosphate-dehydrogenase-cut-off-values-in-a-tunisian-population
#18
Naouel Laouini, Chaima Abdelhafidh Sahli, Latifa Jouini, Sabrine Haloui, Sondes Hadj Fredj, Rym Daboubi, Hajer Siala, Faida Ouali, Meriam Becher, Nourelhouda Toumi, Amina Bibi, Taieb Messsaoud
BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the commonest enzymopathy worldwide. The incidence depends essentially on the methods used for the assessment. In this respect, we attempted in this study to set cut-off values of G6PD activity to discriminate among normal, heterozygous, and deficient individuals using the World Health Organization (WHO) classification and the receiver operating characteristics (ROC) curve analysis. METHODS: Blood samples from 250 female and 302 male subjects were enrolled in this study...
January 18, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28098774/learning-to-diagnose-cirrhosis-with-liver-capsule-guided-ultrasound-image-classification
#19
Xiang Liu, Jia Lin Song, Shuo Hong Wang, Jing Wen Zhao, Yan Qiu Chen
This paper proposes a computer-aided cirrhosis diagnosis system to diagnose cirrhosis based on ultrasound images. We first propose a method to extract a liver capsule on an ultrasound image, then, based on the extracted liver capsule, we fine-tune a deep convolutional neural network (CNN) model to extract features from the image patches cropped around the liver capsules. Finally, a trained support vector machine (SVM) classifier is applied to classify the sample into normal or abnormal cases. Experimental results show that the proposed method can effectively extract the liver capsules and accurately classify the ultrasound images...
January 13, 2017: Sensors
https://www.readbyqxmd.com/read/28098730/novel-classification-system-for-combined-hamartoma-of-the-retina-and-retinal-pigment-epithelium
#20
Vaidehi S Dedania, Cem Ozgonul, David N Zacks, Cagri G Besirli
PURPOSE: To develop an anatomical classification scheme for combined hamartoma of the retina and retinal pigment epithelium (RPE) and specify recommendations for follow-up interval. METHODS: Retrospective review of patients with combined hamartoma of the retina and RPE examined during a 7-year period (2008-2015). The clinical presentation, fundus examination, and optical coherence tomography were analyzed. RESULTS: Lesions were classified based on location, fundus features, and optical coherence tomography findings...
January 16, 2017: Retina
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