Sarah R Tougas, Nidhi Lodha, Ben Vandermeer, Diane L Lorenzetti, Phillip I Tarr, Gillian A M Tarr, Linda Chui, Otto G Vanderkooi, Stephen B Freedman
IMPORTANCE: Detection of Clostridioides difficile has frequently been described in asymptomatic infants and children, but accurate estimates across the age spectrum are unavailable. OBJECTIVE: To assess the prevalence of C difficile detection among asymptomatic children across the age spectrum. DATA SOURCES: This systematic review and meta-analysis included a search of the Cochrane Central Register of Controlled Trials, MEDLINE, Embase, CINAHL, Scopus, and Web of Science for articles published from January 1, 1990, to December 31, 2020...
October 1, 2021: JAMA Pediatrics