Amber N Edinoff, Prithvi K Doppalapudi, Claudia Orellana, Caroline Ochoa, Shelby Patti, Yahya Ghaffar, Elyse M Cornett, Aaron J Kaye, Omar Viswanath, Ivan Urits, Adam M Kaye, Alan D Kaye
Given the typical age onset of schizophrenia, there are tremendous economic and social impacts that extend beyond the person and their families. One critical determinant of the diseases' impact is the patient's adherence to antipsychotic drug treatment. Approved in 2015 for the treatment of schizophrenia, paliperidone palmitate (Invega Trinza, a 3-month injection, noted as PP3M) is a second-generation long-acting injectable antipsychotic medication. Among the different formulations offered for palmitate paliperidone, including the 1 and 3-month formulations, the longer duration 3-month formulation was better at preventing relapse in schizophrenic patients...
2021: Frontiers in Psychiatry