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https://www.readbyqxmd.com/read/29677701/surgical-treatment-and-long-term-outcome-of-cerebral-cavernous-malformations-related-epilepsy-in-pediatric-patients
#1
Qiao Lin, Peng-Fan Yang, Yan-Zeng Jia, Jia-Sheng Pei, Hui Xiao, Ting-Ting Zhang, Zhong-Hui Zhong, Shou-Sen Wang
Cerebral cavernous malformations (CMs) are vascular malformations affecting any part of the central nervous system. Clinical data and surgical outcomes for 27 pediatric patients with CM-related epilepsy were retrospectively reviewed. The mean age of onset was 12.71 ± 4.09 years, and the mean duration of epilepsy was 2.34 ± 1.95 years. All 27 patients were treated with microsurgery for resection of the CMs, and the hemosiderin rim, and the secondary epileptogenic zone if necessary. The mean follow-up period was 6...
April 20, 2018: Neuropediatrics
https://www.readbyqxmd.com/read/29677085/surgical-antimicrobial-prophylaxis-among-pediatric-patients-in-south-africa-comparing-two-healthcare-settings
#2
Nicolene van der Sandt, Natalie Schellack, Lindi A Mabope, Mothahadini Pb Mawela, Danie Kruger, Brian Godman
BACKGROUND: Appropriate use of surgical antimicrobial prophylaxis (SAP) is a concern in view of its impact on morbidity, mortality and costs. Little is currently known about SAP in South Africa. OBJECTIVE: Assess compliance to SAP guidelines for pediatric patients undergoing surgery in one of four surgical sub-specialties among hospitals in South Africa. METHODS: Eight month retrospective chart review in both a teaching hospital and a private hospital between February and August 2015...
April 19, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29676682/growth-and-alignment-of-the-pediatric-subaxial-cervical-spine-following-rigid-instrumentation-and-fusion-a-multicenter-study-of-the-pediatric-craniocervical-society
#3
Hannah E Goldstein, Justin A Neira, Matei Banu, Philipp R Aldana, Bruno P Braga, Douglas L Brockmeyer, Michael L DiLuna, Daniel H Fulkerson, Todd C Hankinson, Andrew H Jea, Sean M Lew, David D Limbrick, Jonathan Martin, Joshua M Pahys, Luis F Rodriguez, Curtis J Rozzelle, Gerald F Tuite, Nicholas M Wetjen, Richard C E Anderson
OBJECTIVE The long-term effects of surgical fusion on the growing subaxial cervical spine are largely unknown. Recent cross-sectional studies have demonstrated that there is continued growth of the cervical spine through the teenage years. The purpose of this multicenter study was to determine the effects of rigid instrumentation and fusion on the growing subaxial cervical spine by investigating vertical growth, cervical alignment, cervical curvature, and adjacent-segment instability over time. METHODS A total of 15 centers participated in this multi-institutional retrospective study...
April 20, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29676289/natural-history-and-outcome-of-inflammatory-bowel-diseases-in-children-in-saudi-arabia-a-single-center-experience
#4
Khalid M Alreheili, Khalid A Alsaleem, Ali I Almehaidib
Background/Aim: Inflammatory bowel disease (IBD) is a chronic gastrointestinal disorder which includes ulcerative colitis (UC), Crohn's disease (CD), and indeterminate colitis (IC). The natural history of pediatric IBDs is poorly understood and generally unpredictable. We aim to study the natural history of IBD in Saudi children including the extraintestinal manifestations, changes in diagnosis, disease behavior, medical management, and surgical outcome. Patients and Methods: A retrospective review of all the charts of children less than 14 years of age who were diagnosed as IBD and followed up in King Faisal Specialist Hospital and Research Center (KFSH and RC) from January 2001 to December 2011 was performed...
April 18, 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/29676162/endoscopic-management-of-primary-obstructive-megaureter-a-systematic-review
#5
Alexander D Doudt, Chad R Pusateri, Matthew Christman
BACKGROUND: The gold standard treatment for primary obstructive megaureter (POM) with declining renal function, worsening obstruction, or recurrent infections is ureteral re-implantation with or without tapering. In infants, open surgery can be technically demanding and associated with significant morbidity. We conducted a systematic review of the literature with special interest in endoscopic management of POM and its outcomes. METHODS: A search was conducted of the MEDLINE/Ovid, PubMed, Embase, and Web of Science databases...
April 20, 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29675756/nodular-macroregenerative-tissue-as-a-pattern-of-regeneration-in-cholangiopathic-disorders
#6
Preston Roberts, Andrew T Trout, Jonathan R Dillman
BACKGROUND: Published case series have described central hepatic macroregenerative nodules or masses as a common feature of Alagille syndrome. Our experience suggests this regenerative pattern can be seen more generally in cholangiopathic disorders. OBJECTIVE: To define the frequency of central regenerative tissue in Alagille syndrome and other cholangiopathic disorders and to describe the typical appearance of such regenerative tissue. MATERIALS AND METHODS: We conducted a retrospective study of CT and MR imaging performed in children and young adults with cholangiopathic disorders between January 2000 and June 2016...
April 19, 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29675081/intra-fourth-ventricular-schwannoma-in-pediatric-age-group-report-of-second-case-in-the-western-literature-with-review-of-literature
#7
Luis Rafael Moscote-Salazar, Guru Dutta Satyarthee, Hector Farid-Escorcia, Willem Guillermo Calderon-Miranda, Huber Said Padilla-Zambrano, Angel Lee, Alfonso Pacheco-Hernandez, Amit Agrawal
Schwannoma originates from the myelin sheath of peripheral nerves. It accounts for about 8% of all intracranial tumors. Commonly, schwannoma is located in the extra-axial locations; intra-axial schwannomas are extremely uncommon. The schwannoma arising from fourth ventricle is extremely uncommon and authors in a detailed PubMed and MEDLINE search could find only seven cases reported in the literature in the form of isolated cases report, who were managed surgically, with only one being a pediatric case. Authors report second case of intra-fourth ventricular schwannoma occurring in the pediatric age group...
October 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29675075/pediatric-cushing-s-disease-dichotomy-in-lateralization-between-imaging-and-inferior-petrosal-sinus-sampling-with-review-of-literature
#8
Salman Tehran Shaikh, Vikram S Karmarkar, Chandrashekhar Eknath Deopujari
Inferior petrosal sinus sampling (IPSS) is a minimally invasive method done in adrenocorticotrophic hormone (ACTH)-dependent pituitary adenoma cases where magnetic resonance imaging (MRI) either gives equivocal results or fails to localize it. A 12-year-girl with cushingoid features and raised ACTH levels presented to us with two consecutive MRI's done outside showing gross change in the morphology of a left-sided pituitary adenoma. Hence, a bilateral IPSS was done which showed a higher IPS/periphery ACTH ratio on the right side as compared to left...
October 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29675067/making-pediatric-neuroanesthesia-safer
#9
REVIEW
Neelakshi Kalita, Amna Goswami, Parthasarathi Goswami
It a challenging task for a Neuroanaesthetist to do the tight rope walking of maintaining the homeostasis of the small baby and at the same time complying with to the demands of the surgery and the surgeon. With the advancement of surgical techniques and availability of safer anaesthetic drugs and equipments it is possible to provide anaesthesia to even premature babies. This article gives a comprehensive review of the anatomical and physiological differences between the adult and the pediatric population and the anaesthetic implications of the various neurosurgical disorders...
October 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29673547/visual-and-semi-automatic-non-invasive-detection-of-interictal-fast-ripples-a-potential-biomarker-of-epilepsy-in-children-with-tuberous-sclerosis-complex
#10
Danilo Bernardo, Hiroki Nariai, Shaun A Hussain, Raman Sankar, Noriko Salamon, Darcy A Krueger, Mustafa Sahin, Hope Northrup, E Martina Bebin, Joyce Y Wu
OBJECTIVES: We aim to establish that interictal fast ripples (FR; 250-500 Hz) are detectable on scalp EEG, and to investigate their association to epilepsy. METHODS: Scalp EEG recordings of a subset of children with tuberous sclerosis complex (TSC)-associated epilepsy from two large multicenter observational TSC studies were analyzed and compared to control children without epilepsy or any other brain-based diagnoses. FR were identified both by human visual review and compared with semi-automated review utilizing a deep learning-based FR detector...
April 3, 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29673417/vitamin-b-12-cyanocobalamin-in-infant-formula-adult-pediatric-nutritional-formula-by-liquid-chromatography-with-ultraviolet-detection-collaborative-study-final-action-2014-02
#11
Ester Campos Giménez, Frédéric Martin
To determine the repeatability and reproducibility figures of the AOAC First Action Official Method SM 2014.02 ( Vitamin B12 in Infant Formula and Adult/Pediatric Formula by Liquid Chromatography with UV Detection ), a collaborative study was organized. Twenty-one laboratories located in 13 different countries agreed to participate. The study was divided into two parts. During the first part, the laboratories analyzed two samples in duplicate by using the method described in the protocol. The laboratories that provided results within the expected range were qualified for part two, during which they analyzed 10 samples in blind duplicates...
April 19, 2018: Journal of AOAC International
https://www.readbyqxmd.com/read/29673268/integration-of-pediatric-behavioral-health-services-in-primary-care-improving-access-and-outcomes-with-collaborative-care
#12
John V Campo, Rose Geist, David J Kolko
OBJECTIVE: To examine collaborative care interventions to integrate pediatric mental health services into primary care as a means of addressing barriers to mental health service delivery, improving access to care, and improving health outcomes. METHOD: Selective review of published literature addressing structural and attitudinal barriers to behavioural health service delivery and the integration of behavioural health services for pediatric mental problems and disorders into primary care settings, with a special focus on Canadian and U...
January 1, 2018: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/29672608/psychosocial-interventions-for-rehabilitation-and-reintegration-into-daily-life-of-pediatric-cancer-survivors-and-their-families-a-systematic-review
#13
Mona Leandra Peikert, Laura Inhestern, Corinna Bergelt
BACKGROUND: The survival rate of childhood cancer patients increased over the past decades. However, even after successful treatment the transition back to normalcy is often a major challenge for the whole family. Therefore, this study aims to provide an overview of psychosocial interventions for childhood cancer survivors and their families in the first years after the end of cancer treatment. METHODS: We conducted a systematic review following the PRISMA Checklist (Preferred Reporting Items for Systematic Reviews and Meta-Analyses; PROSPERO registration number: CRD42017059782)...
2018: PloS One
https://www.readbyqxmd.com/read/29672188/effect-of-inhaled-corticosteroid-use-on-weight-bmi-in-pediatric-patients-with-moderate-severe-asthma
#14
Jennifer Han, John Nguyen, Yuna Kim, Bob Geng, Gale Romanowski, Lawrence Alejandro, James Proudfoot, Ronghui Xu, Sydney Leibel
OBJECTIVES: Assess the relationship between inhaled corticosteroid use (ICS) and weight (BMI) in pediatric patients with moderate-severe asthma. Assess if the number of emergency department (ED) visits correlates with overall BMI trajectory. Assess the trend of prescribing biologic therapy in pediatric patients with moderate-severe asthma and determine its relationship with weight (BMI). METHODS: A retrospective chart review was performed on 93 pediatric patients with moderate-severe asthma to determine the relationship between ICS use and weight (BMI), biologic therapy and BMI, and number of ED visits and BMI trajectory...
April 19, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29672146/childcare-providers-possession-or-use-of-marijuana-tobacco-or-alcohol-while-caring-for-children-a-comparison-of-us-state-regulations
#15
Elyse R Grossman, Sarah Gonzalez-Nahm, Natasha Frost, Sara E Benjamin-Neelon
OBJECTIVES: To evaluate US state regulations regarding marijuana, tobacco, and alcohol to determine the extent to which states attempt to govern these substances in early care and education (ECE) settings. METHODS: Two independent reviewers assessed regulations enacted by December 2016 for all states and the District of Columbia. Reviewers compared regulations to national standards on the possession or use of marijuana, tobacco, and alcohol in ECE settings. RESULTS: Fewer states regulated marijuana than tobacco or alcohol in ECE settings...
April 19, 2018: American Journal of Public Health
https://www.readbyqxmd.com/read/29671293/surgical-treatment-for-refractory-epilepsy
#16
Johannes Herta, Christian Dorfer
The goal of any epilepsy surgery is to improve patient ́s quality of life by achieving seizure freedom or by reducing the frequency of severely debilitating seizures. To achieve this goal, non-invasive and invasive diagnostic methods must precisely delineate the epileptogenic zone (EZ), which is defined as the area that needs to be resected to obtain seizure freedom. At the same time, the correct identification of eloquent brain areas is inevitable to avoid new neurological deficits from surgery. In recent years, the technical advances in diagnostics have enabled us to achieve these goals in an increasing number of cases...
April 18, 2018: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/29671100/pediatric-type-2-diabetes-in-japan-similarities-and-differences-from-type-2-diabetes-in-other-pediatric-populations
#17
REVIEW
Tatsuhiko Urakami
PURPOSE OF REVIEW: To review clinical characteristics of pediatric type 2 diabetes in Japan. RECENT FINDINGS: It is well recognized that Asian populations, particularly the Japanese, have a higher incidence of childhood type 2 diabetes. Of note, most Asian populations show a higher incidence of pediatric type 2 diabetes than that of type 1 diabetes. However, a current report in the USA demonstrated a dramatic increase in the incidence of young people with type 2 diabetes in recent years...
April 18, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29671081/type-2-diabetes-mellitus-the-metabolic-syndrome-and-its-components-in-adult-survivors-of-acute-lymphoblastic-leukemia-and-hematopoietic-stem-cell-transplantations
#18
REVIEW
Bella Bielorai, Orit Pinhas-Hamiel
PURPOSE OF REVIEW: A growing number of pediatric acute lymphoblastic leukemia (ALL) and hematopoietic stem cell transplantation (HSCT) survivors reach adulthood and face long-term health-related problems. We review risk factors and the prevalence of the metabolic syndrome (MetS), a cluster of obesity-related comorbidities, including abdominal obesity, atherogenic dyslipidemia, elevated blood pressure, impaired glucose metabolism, and type 2 diabetes in ALL and HSCT survivors. RECENT FINDINGS: Components of the MetS are already detected during the first year of ALL maintenance therapy and significantly worsen over time...
April 18, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29671067/vaccinations-in-pediatric-kidney-transplant-recipients
#19
REVIEW
Thomas G Fox, Corina Nailescu
Pediatric kidney transplant (KT) candidates should be fully immunized according to routine childhood schedules using age-appropriate guidelines. Unfortunately, vaccination rates in KT candidates remain suboptimal. With the exception of influenza vaccine, vaccination after transplantation should be delayed 3-6 months to maximize immunogenicity. While most vaccinations in the KT recipient are administered by primary care physicians, there are specific schedule alterations in the cases of influenza, hepatitis B, pneumococcal, and meningococcal vaccinations; consequently, these vaccines are usually administered by transplant physicians...
April 18, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29670869/pathogenetic-and-prognostic-factors-for-neonatal-gastric-perforation-personal-experience-and-systematic-review-of-the-literature
#20
Chiara Iacusso, Alessandro Boscarelli, Fabio Fusaro, Pietro Bagolan, Francesco Morini
Introduction: Neonatal gastric perforation (NGP) is a rare entity. Our aim was to report our experience and review the recent literature to characterize NGP, describe associated factors, and define prognostic factors. Materials and methods: Retrospective review of all consecutive patients with NGP treated between June 2009 and December 2017 in a third level pediatric hospital. In addition, a systematic review of Medline and Scopus database was performed using a defined strategy...
2018: Frontiers in Pediatrics
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