keyword
MENU ▼
Read by QxMD icon Read
search

Review pediatric

keyword
https://www.readbyqxmd.com/read/29058370/proton-therapy-for-pediatric-head-and-neck-malignancies
#1
Jennifer Vogel, Stefan Both, Maura Kirk, Hann-Hsiang Chao, Rochelle Bagatell, Yimei Li, Richard Womer, Naomi Balamuth, Anne Reilly, Goldie Kurtz, Robert Lustig, Zelig Tochner, Christine Hill-Kayser
PURPOSE: Pediatric head and neck malignancies are managed with intensive multimodality therapy. Proton beam therapy (PBT) may reduce toxicity by limiting exposure of normal tissue to radiation. In this study, we report acute toxicities and early outcomes following PBT for pediatric head and neck malignancies. MATERIALS AND METHODS: Between 2010 and 2016, pediatric patients with nonhematologic malignancies of the head and neck were treated with PBT. Clinical and dosimetric data were abstracted from the medical record and treatment planning system with institutional review board approval...
October 23, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29058300/trisomy-21-with-t-5-11-chromosomal-translocation-as-new-unfavorable-cytogenetic-abnormalities-in-pediatric-acute-myeloid-leukemia-type-m2-one-case-report-of-nine-year-follow-up-and-literature-review
#2
Lin Wang, Xiao-Yan Wu, Run-Ming Jin, Bing-Yu Zhang, Yi-Ning Qiu
We report one case of pediatric acute myeloid leukemia type 2 (AML-M2) who presented with karyotypic aberration of trisomy 21 with the t(5;11) chromosomal translocation. The patient achieved complete remission after two cycles of chemotherapy of daunorubicin, cytarabine and etoposide. Then, follow-up cytogenetic analysis from bone marrow cell cultures demonstrated a normal karyotype of 46, XY. After 9 years, the patient relapsed and the karyotypic abnormalities of trisomy 21 with t(5;11) reappeared. It was concluded that trisomy 21 with t(5; 11) is a new unfavorable cytogenetic aberration in AML-M2...
October 2017: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/29058268/early-diagnosed-cerebrotendinous-xanthomatosis-patients-clinical-neuroradiological-characteristics-and-therapy-results-of-a-single-center-from-turkey
#3
Tanyel Zubarioglu, Ertugrul Kiykim, Gozde Yesil, Duhan Demircioglu, Mehmet Serif Cansever, Cengiz Yalcinkaya, Cigdem Aktuglu-Zeybek
Cerebrotendinous xanthomatosis (CTX) is a lipid storage disorder caused by defective sterol 27-hydroxylase activity. In spite of subtle clinical signs beginning from childhood, CTX is generally diagnosed lately. The aim of this study is to evaluate clinical, neuroradiological findings and therapy responses of pediatric CTX patients and raise awareness to early features of disease. Patients who were molecularly diagnosed as CTX before 18 years of age were included in study. Clinical, epidemiological, radiological and genotypic features of patients and chenodeoxycholic acid (CDCA) therapy responses were reviewed retrospectively...
October 22, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/29058250/trends-of-childhood-diabetes-in-southern-thailand-20-year-experience-in-a-tertiary-medical-center
#4
Somchit Jaruratanasirikul, Sudarat Thammaratchuchai, Hutcha Sriplung
BACKGROUND: The incidence and/or prevalence of both childhood diabetes and the percent of type 2 diabetes mellitus (T2DM) cases in children and young adolescents have been increasing worldwide. This study aimed to examine the 20-year trends of childhood diabetes in a single tertiary medical center in Southern Thailand. METHODS: The medical records of pediatric diabetic patients, aged 0-15 years, diagnosed at Songklanagarind Hospital from 1995 to 2014 were retrospectively reviewed...
December 2017: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/29058244/long-term-outcomes-of-ahmed-tube-implantation-in-pediatric-glaucoma-after-multiple-surgeries
#5
Christiane Al-Haddad, Khalil Al-Salem, Karine Ismail, Baha' Noureddin
PURPOSE: To report success of Ahmed glaucoma valve (AGV) implantation in eyes with pediatric glaucoma and subconjunctival scarring from previous surgeries. METHODS: A retrospective review of pediatric glaucoma patients who underwent AGV implantation after ≥ 2 previous surgeries with conjunctival scarring. Preoperative and postoperative parameters were recorded to study success, defined as intraocular pressure (IOP) < 22 mmHg with or without medications and without serious complications...
October 20, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/29058039/agreement-between-manual-relaxometry-and-semi-automated-scanner-based-multi-echo-dixon-technique-for-measuring-liver-t2-in-a-pediatric-and-young-adult-population
#6
Suraj D Serai, Ethan A Smith, Andrew T Trout, Jonathan R Dillman
BACKGROUND: Commercially available 3D multi-echo Dixon (mDixon) sequences provide parametric maps of liver T2*, obviating manual curve fitting that is often required with conventional gradient recalled echo (GRE)-based multi-echo relaxometry, potentially simplifying clinical work flow. OBJECTIVE: The purpose of our study was to compare T2* values generated by a 3D mDixon sequence to values generated by GRE-based T2* relaxometry with manual curve fitting in a pediatric and young adult population...
October 23, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/29057682/improving-diagnosis-of-childhood-stroke-arterial-ischemic-stroke
#7
Mark T Mackay, Paul Monagle, Franz E Babl
At least half of childhood stroke survivors suffer long-term impairments. Rapid identification of stroke is essential to minimize the extent of injury by restoring perfusion to viable brain. Improving diagnosis of childhood stroke requires correct identification of stroke by prehospital and emergency physicians, rapid performance of appropriate neuroimaging to confirm infarction, and targeted investigations to determine underlying causes, which guide treatment decisions to reduce recurrence risk. Areas covered: This review will summarize the barriers to rapid stroke diagnosis in pre-hospital and emergency department settings, describe recent progress in understanding of the spectrum, presenting clinical features and differential diagnosis of childhood stroke, discuss clinical stroke recognition tools which improve diagnostic accuracy, and their application to children...
October 23, 2017: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/29057670/do-parents-and-children-agree-on-rating-a-child-s-hrqol-a-systematic-review-and-meta-analysis-of-comparisons-between-children-with-attention-deficit-hyperactivity-disorder-and-children-with-typical-development-using-the-pedsql-tm
#8
Yi-Chen Lee, Hao-Jan Yang, Wan-Ting Lee, Ming-Jen Teng
PURPOSE: This meta-analysis was conducted to assess differences in a child's health-related quality of life (HRQOL) as reported by the child and their parents using the Pediatric Quality of Life Inventory(TM), and the effects in both children with attention deficit hyperactivity disorder (ADHD) and those with typical development. METHODS: Eight studies encompassing 16 independent groups met the inclusion criteria and were combined and compared in this meta-analysis...
October 23, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29057347/indirect-pars-repair-for-pediatric-isthmic-spondylolysis-a-case-series
#9
Brandon L Raudenbush, Reid C Chambers, Michael P Silverstein, Ryan C Goodwin
BACKGROUND: Isthmic spondylolysis (ISY) is a common cause of back pain in the pediatric population. Historically, non-operative treatments have had a very high success rate. The purpose of this study was to review the mid-term results of an indirect pars repair technique on reducing the visual analog score for pain (VAS), spondylolysis defect healing, complication rates and rates of return to pre-surgery activity level in pediatric patients who failed conservative care for ISY. METHODS: A retrospective review of all pediatric patients (<18 years old) treated surgically by one surgeon over a 5-year period was performed...
September 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29057163/characterization-of-long-working-distance-optical-coherence-tomography-for-imaging-of-pediatric-retinal-pathology
#10
Ruobing Qian, Oscar M Carrasco-Zevallos, Shwetha Mangalesh, Neeru Sarin, Lejla Vajzovic, Sina Farsiu, Joseph A Izatt, Cynthia A Toth
PURPOSE: We determined the feasibility of fovea and optic nerve head imaging with a long working distance (LWD) swept source optical coherence tomography (OCT) prototype in adults, teenagers, and young children. METHODS: A prototype swept source OCT system with a LWD (defined as distance from the last optical element of the imaging system to the eye) of 350 mm with custom fixation targets was developed to facilitate imaging of children. Imaging was performed in 49 participants from three age groups: 26 adults, 16 children 13 to 18 years old (teenagers), and seven children under 6 years old (young children) under an approved institutional review board protocol...
October 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/29056870/an-update-on-childhood-lead-poisoning
#11
Marissa Hauptman, Rebecca Bruccoleri, Alan D Woolf
Childhood lead poisoning is a multi-faceted, complex condition, which affects not only the child's health and well-being, but also the family's housing security, economic status, job security, and stress level. This review updates the emergency department clinician on the management of childhood lead poisoning. Infants and children are at higher risk than adults for lead exposure due to their smaller size and proportionately larger dose of ingested toxins, their proximity to ground dirt and indoor dust, their energy and curiosity, their oral exploratory and pica behaviors, their proportionately larger daily water and milk intake, and dietary preferences that differ markedly from those of adults...
September 2017: Clinical Pediatric Emergency Medicine
https://www.readbyqxmd.com/read/29056166/long-term-adverse-events-associated-with-acute-kidney-injury
#12
Manisha Singh, Nithin Karakala, Sudhir V Shah
Acute kidney injury (AKI) occurs in approximately 10% to 15% of hospital-admitted patients and is associated with in-hospital mortality of 50% in patients requiring renal replacement therapy. Recently, multiple observational studies have demonstrated that patients who survive AKI have significant long-term consequences including cardiovascular events, progression to advanced-stage chronic kidney disease (CKD), and mortality. A direct link between AKI and CKD is provided by studies that demonstrate that some patients with normal renal function who develop AKI requiring dialysis never recover...
November 2017: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/29055868/rescue-medications-in-epilepsy-patients-a-family-perspective
#13
Marina Gaínza-Lein, Robert Benjamin, Coral Stredny, Marlee McGurl, Kush Kapur, Tobias Loddenkemper
PURPOSE: The aim of this study was to analyze pre-hospital seizure rescue medication (RM) use in a pediatric epilepsy population, caregiver knowledge and comfort, and prescription patterns. METHOD: Cross-sectional observational study based on surveys to families of pediatric patients with epilepsy and based on medical chart review. RESULTS: One hundred (92.6%) out of 114 families answered the questionnaire. Fifty-five patients were females (55%), with a median (IQR) age of 11 (6-14) years...
October 13, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29055602/late-graft-dysfunction-after-pediatric-heart-transplantation-is-associated-with-fibrosis-and-microvasculopathy-by-automated-digital-whole-slide-analysis
#14
Brian Feingold, Jennifer Picarsic, Andrew Lesniak, Benjamin A Popp, Michelle A Wood-Trageser, Anthony J Demetris
BACKGROUND: Histopathologic features of late graft dysfunction (LGD) in endomyocardial biopsies (EMBs) after pediatric heart transplantation (HT) have been incompletely described and rarely quantified. We employed automated, morphometric analysis of whole-slide EMB images to objectively quantify fibrosis and microvasculopathy after pediatric HT. METHODS: Nine recipients with clinical LGD were matched with controls on age, listing diagnosis, crossmatch and time since HT...
September 29, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29055500/long-term-systemic-corticosteroid-exposure-a-systematic-literature-review
#15
REVIEW
J Bradford Rice, Alan G White, Lauren M Scarpati, George Wan, Winnie W Nelson
PURPOSE: While corticosteroids are relatively inexpensive and commonly used as treatment for a variety of conditions, long-term use is known to be associated with certain toxicities. Prior systematic reviews have revealed an increased risk for costly adverse events (AEs), including bone fracture, infection, and gastrointestinal bleeding. The objective of this study was to conduct a systematic literature review of recent publications on the burden of long-term corticosteroid exposure, specifically, to summarize the AEs and economic impact of long-term corticosteroid use and to reveal data gaps for additional research...
October 18, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/29054981/immunoadsorption-in-anti-gbm-glomerulonephritis-case-report-in-a-child-and-literature-review
#16
Guillaume Dorval, Mathilde Lion, Sophie Guérin, Saoussen Krid, Louise Galmiche-Rolland, Rémi Salomon, Olivia Boyer
Antiglomerular basement membrane glomerulonephritis (anti-GBM GN) is a rare autoimmune disease that is characterized by rapidly progressive glomerulonephritis that may be associated with pulmonary hemorrhage. Anti-GBM GN is caused by autoantibodies (classically type G immunoglobulin) directed against the α3 subunit of type IV collagen. Without any appropriate treatment, the disease is generally fulminant, and patient and kidney survival is poor. The current guidelines recommend the use of plasma exchanges and immunosuppressive drugs...
October 20, 2017: Pediatrics
https://www.readbyqxmd.com/read/29054779/prevalence-characteristics-and-long-term-prognosis-of-epilepsy-associated-with-pediatric-brain-tumors
#17
Hadar Weisman, Iris Fried, Tal Gilboa, Odeya Bennett-Back, Dana Ekstein, Moatasem Shweiki, Yigal Shoshan, Mony Benifla
OBJECTIVE: We investigated the prevalence, onset, characteristics and long-term course of epilepsy disease in children who underwent surgical intervention for diagnosed brain tumors. METHODS: We reviewed the medical records of children with diagnosed brain tumors, who underwent surgery during 2004-2014 at the Hadassah Medical Center. All patients with epilepsy were invited to a clinical visit that included a neurological exam. The primary outcome measures were neurological status according to the Glasgow Outcome Scale (GOS) and postoperative seizure outcome according to the Engel system...
October 17, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29053056/intradural-spine-surgery-may-not-carry-an-increased-risk-of-shunt-revision-compared-with-extradural-spine-surgery-in-pediatric-patients-with-myelomeningocele
#18
Elizabeth N Kuhn, Betsy Hopson, Michael J Conklin, Jeffrey P Blount
OBJECTIVE Patients with myelomeningocele are often affected by scoliosis and tethered cord syndrome, and frequently require spine surgery. Intradural spine surgeries may carry an inherently higher risk of inducing shunt malfunction due to entry into the subarachnoid space. In this study, the authors sought to compare rates of shunt malfunction after intradural and extradural spine surgeries among pediatric patients with myelomeningocele. METHODS The authors reviewed records of the National Spina Bifida Program Registry for Children's Hospital of Alabama...
October 20, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29052770/extrapulmonary-involvement-in-pediatric-tuberculosis
#19
REVIEW
Supika Kritsaneepaiboon, Mariaem M Andres, Vincent R Tatco, Cielo Consuelo Q Lim, Nathan David P Concepcion
Tuberculosis in childhood is clinically challenging, but it is a preventable and treatable disease. Risk factors depend on age and immunity status. The most common form of pediatric tuberculosis is pulmonary disease, which comprises more than half of the cases. Other forms make up the extrapulmonary tuberculosis that involves infection of the lymph nodes, central nervous system, gastrointestinal system, hepatobiliary tree, and renal and musculoskeletal systems. Knowledge of the imaging characteristics of pediatric tuberculosis provides clues to diagnosis...
September 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/29052734/diagnostic-performance-of-magnetic-resonance-enterography-for-detection-of-active-inflammation-in-children-and-adolescents-with-inflammatory-bowel-disease-a-systematic-review-and-diagnostic-meta-analysis
#20
Hee Mang Yoon, Chong Hyun Suh, Jeong Rye Kim, Jin Seong Lee, Ah Young Jung, Kyung Mo Kim, Young Ah Cho
Importance: Magnetic resonance (MR) enterography has the advantage over other techniques of being noninvasive, lacking ionizing radiation, and demonstrating excellent soft-tissue contrast to evaluate pediatric patients with inflammatory bowel disease (IBD). Objective: To evaluate the diagnostic performance of MR enterography for detection of active inflammation in children and adolescents with known or suspected IBD. Data Sources: A search of MEDLINE and EMBASE up to January 2, 2017, was performed to identify studies...
October 9, 2017: JAMA Pediatrics
keyword
keyword
70679
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"