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https://www.readbyqxmd.com/read/29913026/long-term-outcomes-after-same-amount-of-bilateral-rectus-muscle-recession-for-intermittent-exotropia-with-the-same-angle-of-deviation
#1
Haeng-Jin Lee, Seong-Joon Kim, Young Suk Yu
PURPOSE: To evaluate long-term outcomes of homogenous bilateral rectus recession in patients with the same preoperative angle of deviation in intermittent exotropia and investigate factors associated with surgical outcomes. METHODS: In this retrospective review, patients with the same preoperative angle of deviation who underwent bilateral 6-mm lateral rectus recession between January 2008 and January 2014 were observed for 2 or more years. Patients were classified into two groups based on deviation angle: success (orthophoria or exodeviation < 10 prism diopters [PD]) or recurrence (exodeviation ≥ 10 PD)...
June 18, 2018: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29913025/one-muscle-strabismus-surgery-a-review
#2
Jake Gurland, Aldo Vagge, Leonard B Nelson
Proper management of a patient with small to moderate horizontal deviations continues to be challenging for the strabismus surgeon. The use of one-muscle surgery for comitant strabismus has been controversial because of concerns that it may result in a significant number of undercorrections and/or ocular incomitance. Recent literature on unilateral rectus muscle surgery has shown that this surgery is a safe and effective procedure for small and moderate angle horizontal deviations. It has the advantage of limiting surgery to one eye, reducing operative time and possible cost to the family, and leaving other muscles untouched in case repeat surgery is necessary...
June 18, 2018: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29913023/immediate-postoperative-alignment-following-bimedial-rectus-recession-for-esotropia-in-children-compared-to-adults
#3
Mohamed B Hassan, Nancy N Diehl, Brian G Mohney
PURPOSE: To determine whether the immediate postoperative alignment among patients undergoing successful bilateral weakening surgery for esotropia is different in children compared to adults. METHODS: The medical records of all patients undergoing surgery for esotropia by a single surgeon at a major academic referral center between January 1, 2002, and July 1, 2014 (n = 544), were retrospectively reviewed. Exclusion criteria included those with prior strabismus surgery, unilateral surgery, strengthening procedures, vertical or superior oblique surgery, and those wearing hyperopic spectacles for accommodative esotropia...
June 18, 2018: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29912838/baha-skin-complications-in-the-pediatric-population-systematic-review-with-meta-analysis
#4
Scott Shapiro, Jad Ramadan, Adam Cassis
OBJECTIVE: Compare the incidence of skin and surgical site complications for children undergoing percutaneous and transcutaneous bone conduction implant (pBCI and tBCI) surgery via systematic review and meta-analysis of the available data. DATA SOURCES: 1) Search of PubMed, Web of Science, and EBSCOhost databases from January 2012 to April 2017. 2) References of studies meeting initial criteria. STUDY SELECTION: Inclusion criteria were studies that involved patients less than 18 years old undergoing tBCI or pBCI surgery with a BI300 implant and reported skin complications, implant loss, and need for revision surgery...
June 15, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29912823/individualized-learning-plan-ilp-is-an-effective-tool-in-assessing-achievement-of-otology-related-subcompetency-milestones
#5
Maja Svrakic, John P Bent
OBJECTIVE: To investigate the individualized learning plan (ILP) as a tool in assessment of residents' milestone achievements as they pertain to Otology subcompetencies: Chronic Ear Disease, Pediatric Otitis Media, and Hearing Loss. STUDY DESIGN: Prospective study. METHODS: Twenty otolaryngology residents were instructed to use an ILP and identify six milestones from three otology-related subcompetencies to focus on during the course of a 3-month rotation...
June 15, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29912812/multicenter-review-of-current-practices-associated-with-venous-thromboembolism-prophylaxis-in-pediatric-patients-after-trauma
#6
Amee M Bigelow, Katherine T Flynn-O'Brien, Pippa M Simpson, Mahua Dasgupta, Sheila J Hanson
OBJECTIVES: Frequency of venous thromboembolism in pediatric trauma patients admitted to PICUs is not insignificant, ranging up to 6%. Risk factors have been identified in this population. However, there is little consensus of actual venous thromboembolism prophylaxis practice. We examined factors associated with venous thromboembolism prophylaxis in PICUs. DESIGN: A retrospective study evaluating associations with mechanical venous thromboembolism prophylaxis, pharmacologic venous thromboembolism prophylaxis, or dual therapy (DUAL) prophylaxis compared with no venous thromboembolism prophylaxis...
June 15, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29912581/posaconazole-in-immunocompromised-pediatric-patients
#7
Edoardo Bruno Vicenzi, Simone Cesaro
INTRODUCTION: Posaconazole is a broad-spectrum triazole widely used to prevent and treat invasive mycoses in adults. Since it received marketing authorization more than a decade ago, many authors have reported on its off-label use in pediatric patients, despite the fact that the pharmacokinetics, safety and efficacy in children have not been extensively investigated. AREAS COVERED: We reviewed pediatric studies published between 2010 and 2017 describing the prophylactic and therapeutic use of posaconazole, with special attention to the correlation between oral dose, plasma levels, safety, and effectiveness...
June 18, 2018: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/29912249/-peritoneal-dialysis-related-infections-in-pediatric-patients-diagnosis-and-treatment-review
#8
M Carolina Rivacoba, M Luisa Ceballos, Paulina Coria
Peritoneal dialysis-related infections are the main complication in pediatric patients undergoing this renal replacement therapy, associating a high rate of morbidity, generating also a decreasing survival of the peritoneal membrane and worsening the patient outcome. We describe the recommended diagnostic and therapeutic modalities to treat dialysis-related in children.
April 2018: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/29912087/ocular-injury-presenting-to-a-level-iii-pediatric-trauma-center
#9
Kari Schneider, Hai Nguyen-Tran, Bradley J Segura, Raymond G Areaux, Dan Nerheim, Jeffrey P Louie
The purpose of this study is to describe pediatric ocular injuries presenting to a level-III pediatric trauma center and emergency department. METHODS: We performed a retrospective study and identified children from January 1, 2011, to January 1, 2016. Charts were reviewed for any subject, age from newborn to younger than 18 years, based on International Classification of Diseases, ninth and tenth revision, codes for any ocular injury. Data abstraction included age, sex, means of arrival, eye involved, mechanism of injury, type of ocular injury, imaging studies obtained, procedures performed, location of definitive repair (in the operating room or emergency department), and subspecialty services involved...
June 14, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29912083/caring-for-pediatric-patients-with-epidermolysis-bullosa-in-the-emergency-department
#10
Helena A Jenkinson, Ashley D Lundgren, Moise L Levy, Lucia Z Diaz
Epidermolysis bullosa (EB) refers to a heterogeneous group of genetic disorders characterized by epithelial fragility. We provide guidelines for management of pediatric patients with EB in the emergency department based on a review of literature, as well as insights from our own experiences caring for patients with EB. The purpose of the guidelines proposed is prevention of avoidable iatrogenic trauma to the skin and mucosa of patients with EB who are presenting to the emergency department for a variety of reasons...
June 14, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29912033/analysis-of-healthcare-institutional-costs-of-pediatric-home-parenteral-nutrition-central-line-infections
#11
Bram P Raphael, Christina Hazenkamp, Mihail Samnaliev, Al Ozonoff
BACKGROUND: While previous literature suggests home parenteral nutrition (HPN) dependent children experience frequent complications like community acquired central line associated bloodstream infections (CLABSI), few studies have characterized the cost. OBJECTIVES: To evaluate institutional cost of community-acquired CLABSI in pediatric HPN patients. METHODS: This is a single center retrospective review of institutional costs for HPN patients with community-acquired CLABSI at a tertiary care children's hospital...
June 13, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29911755/emergencies-in-the-treatment-of-wandering-spleen
#12
Osher Cohen, Arthur Baazov, Inbal Samuk, Michael Schwarz, Dragan Kravarusic, Enrique Freud
BACKGROUND: Wandering spleen is a rare entity that may pose a surgical emergency following torsion of the splenic vessels, mainly because of a delayed diagnosis. Complications after surgery for wandering spleen may necessitate emergency treatment. OBJECTIVES: To describe the clinical course and treatment for children who underwent emergency surgeries for wandering spleen at a tertiary pediatric medical center over a 21 year period and to indicate the pitfalls in diagnosis and treatment as reflected by our experience and in the literature...
June 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29911511/adherence-in-youth-with-multiple-sclerosis-a-qualitative-assessment-of-habit-formation-barriers-and-facilitators
#13
E Ann Yeh, Nicole Chiang, Bindia Darshan, Nadine Nejati, Stephanie A Grover, Carolyn E Schwartz, Ruth Slater, Marcia Finlayson
Rates of medication nonadherence in youth with multiple sclerosis (MS) range from 10% to 60%. Qualitative studies of adherence can provide insight into children's own perspectives about barriers and facilitators to their adherence and inform future interventions. This qualitative longitudinal descriptive study included children with MS ( n = 28) participating in a randomized controlled trial focused on medication adherence ( clinicaltrials.gov : NCT02234713). Following established methods, three independent reviewers coded transcripts of motivational interviewing (MI) sessions (three interviews per subject, performed monthly over a 3-month period) for relevant themes...
June 1, 2018: Qualitative Health Research
https://www.readbyqxmd.com/read/29911246/circulating-serum-oncologic-mirna-in-pediatric-juvenile-pilocytic-astrocytoma-patients-predicts-mural-nodule-volume
#14
Markus Bookland, Min Tang-Schomer, Eileen Gillan, Antonina Kolmakova
BACKGROUND: Juvenile pilocytic astrocytomas represent the largest group of pediatric brain tumors. The ideal management for these tumors is early, total surgical resection. To detect and track treatment response, a screening tool is needed to identify patients for surgical evaluation and assess the quality of treatment. The identification of aberrant miRNA profiles in the sera of juvenile pilocytic astrocytoma patients could provide such a screening tool. METHODS: The authors reviewed the serum profiles of 84 oncologically relevant miRNAs in pediatric juvenile pilocytic astrocytoma patients via qPCR screening...
June 18, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29911134/titanium-elastic-nails-versus-spica-cast-in-pediatric-femoral-shaft-fractures-a-systematic-review-and-meta-analysis-of-1012-patients
#15
REVIEW
Mohamed A Imam, Ahmed S Negida, Ahmed Elgebaly, Amr Samy Hussain, Lukas Ernstbrunner, Saqib Javed, Joshua Jacob, Mark Churchill, Paul Trikha, Kevin Newman, David Elliott, Arshad Khaleel
Background: There is a general consensus on the management of femoral fractures in children younger than two years and adolescents older than sixteen years. The best treatment for patients younger than sixteen years of age is still debatable. Titanium Elastic Nails (TEN), is widely used with some evidence, nonetheless, we undertook a systematic meta-analysis to assess the efficacy of TEN compared to Spica cast for the management of femoral shaft fracture in children aged between 2 to 16 years old...
May 2018: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/29910631/clonidine-versus-other-adjuncts-added-to-local-anesthetics-for-pediatric-neuraxial-blocks-a-systematic-review-and-meta-analysis
#16
REVIEW
Yang Yang, Ling-Yu Yu, Wen-Sheng Zhang
Background: Clonidine is a common adjunct to local anesthetics for pediatric neuraxial block; however, the pros and cons between clonidine and other adjuncts remain unclear. Thus, we performed this meta-analysis of randomized controlled trials to assess the efficacy and adverse effects between clonidine and other adjuncts added to local anesthetics. Materials and methods: The systematic search, data extraction, critical appraisal, and pooled analysis were performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29910555/adult-influenza-a-h1n1-related-encephalitis-a-case-report
#17
Devinder Midha, Arun Kumar, Pratibha Vasudev, Zafar Ahmad Iqbal, Amit Kumar Mandal
The year 2009-2010 saw H1N1 influenza outbreaks occurring in almost all countries of the world, causing the WHO to declare it a pandemic of an alert level of 6. In India, H1N1 influenza outbreaks were again reported in late 2014 and early 2015. Since then, sporadic cases of H1N1 influenza have been reported. H1N1 influenza usually presents itself with respiratory tract symptoms. In a minority of patients, abdominal symptoms may occur as well. Acute influenza-associated encephalopathy/encephalitis mostly occurs in the pediatric population, whereas in adults, it is a rare complication...
May 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/29910543/clinicohematological-profile-of-febrile-neutropenia-in-childhood-acute-leukemia-and-utility-of-serum-procalcitonin-levels-in-neutropenic-patients
#18
Rajan Kapoor, Ashish K Simalti, Shuvendu Roy, Pulkit Agarwal
Introduction: This study was planned to explore the clinical and hematological profile of febrile neutropenia (FN) in Indian children with focus on correlation of degree of neutropenia with fever and procalcitonin (PCT) level and the utility of serum PCT levels in cases of FN. Materials and Methods: Children below 12 years, receiving chemotherapy for hematological malignancy having oral temperature more than 100°F and absolute neutrophil count (ANC) below 500/mm3 were included...
May 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/29910527/the-food-and-drug-administration-s-federal-review-of-a-pediatric-muscular-dystrophy-protocol
#19
Donna L Snyder, Robert M Nelson
No abstract text is available yet for this article.
January 2018: IRB
https://www.readbyqxmd.com/read/29910006/toward-a-variable-rbe-for-proton-beam-therapy
#20
REVIEW
Henning Willers, Antino Allen, David Grosshans, Stephen J McMahon, Cläre von Neubeck, Claudia Wiese, Bhadrasain Vikram
In the clinic, proton beam therapy (PBT) is based on the use of a generic relative biological effectiveness (RBE) of 1.1 compared to photons in human cancers and normal tissues. However, the experimental basis for this RBE lacks any significant number of representative tumor models and clinically relevant endpoints for dose-limiting organs at risk. It is now increasingly appreciated that much of the variations of treatment responses in cancers are due to inter-tumoral genomic heterogeneity. Indeed, recently it has been shown that defects in certain DNA repair pathways, which are found in subsets of many cancers, are associated with a RBE increase in vitro...
June 14, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
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