Moninder Kaur, Levon Utidjian, Nicholas S Abend, Kimberley Dickinson, Robert Roebling, Jill McDonald, Mitchell G Maltenfort, Nadia Foskett, Sami Elmoufti, Rejean M Guerriero, Badal G Jain, Nathan M Pajor, Suchitra Rao, Renée A Shellhaas, Laurel Slaughter, Christopher B Forrest
BACKGROUND: There is growing evidence supporting the safety and effectiveness of lacosamide in older children. However, minimal data are available for neonates. We aimed to determine the incidence of adverse events associated with lacosamide use and explore the electroencephalographic seizure response to lacosamide in neonates. METHODS: A retrospective cohort study was conducted using data from seven pediatric hospitals from January 2009 to February 2020. For safety outcomes, neonates were followed for ≤30 days from index date...
March 13, 2024: Pediatric Neurology