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https://www.readbyqxmd.com/read/28934951/communicating-projected-survival-with-treatments-for-chronic-kidney-disease-patient-comprehension-and-perspectives-on-visual-aids
#1
Frances Dowen, Karishma Sidhu, Elizabeth Broadbent, Helen Pilmore
BACKGROUND: Mortality in end stage renal disease (ESRD) is higher than many malignancies. There is no data about the optimal way to present information about projected survival to patients with ESRD. In other areas, graphs have been shown to be more easily understood than narrative. We examined patient comprehension and perspectives on graphs in communicating projected survival in chronic kidney disease (CKD). METHODS: One hundred seventy-seven patients with CKD were shown 4 different graphs presenting post transplantation survival data...
September 21, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28934277/double-edged-sword-of-interdisciplinary-knowledge-flow-from-hard-sciences-to-humanities-and-social-sciences-evidence-from-china
#2
Meijun Liu, Dongbo Shi, Jiang Li
Humanities and Social Sciences (HSS) increasingly absorb knowledge from Hard Sciences, i.e., Science, Technology, Agriculture and Medicine (STAM), as testified by a growing number of citations. However, whether citing more Hard Sciences brings more citations to HSS remains to be investigated. Based on China's HSS articles indexed by the Web of Science during 1998-2014, this paper estimated two-way fixed effects negative binomial models, with journal effects and year effects. Findings include: (1) An inverse U-shaped curve was observed between the percentage of STAM references to the HSS articles and the number of citations they received; (2) STAM contributed increasing knowledge to China's HSS, while Science and Technology knowledge contributed more citations to HSS articles...
2017: PloS One
https://www.readbyqxmd.com/read/28933778/synthesis-of-a-hycosul-peptide-substrate-library-to-dissect-protease-substrate-specificity
#3
Marcin Poreba, Guy S Salvesen, Marcin Drag
Many biologically and chemically based approaches have been developed to design highly active and selective protease substrates and probes. It is, however, difficult to find substrate sequences that are truly selective for any given protease, as different proteases can demonstrate a great deal of overlap in substrate specificities. In some cases, better enzyme selectivity can be achieved using peptide libraries containing unnatural amino acids such as the hybrid combinatorial substrate library (HyCoSuL), which uses both natural and unnatural amino acids...
October 2017: Nature Protocols
https://www.readbyqxmd.com/read/28925989/development-of-a-symptom-focused-patient-reported-outcome-measure-for-functional-dyspepsia-the-functional-dyspepsia-symptom-diary-fdsd
#4
Fiona Taylor, Sophie Higgins, Robyn T Carson, Sonya Eremenco, Catherine Foley, Brian E Lacy, Henry P Parkman, David S Reasner, Alan L Shields, Jan Tack, Nicholas J Talley
OBJECTIVES: The Functional Dyspepsia Symptom Diary (FDSD) was developed to address the lack of symptom-focused, patient-reported outcome (PRO) measures designed for use in functional dyspepsia (FD) patients and meeting Food and Drug Administration recommendations for PRO instrument development. METHODS: Concept elicitation interviews were conducted with FD participants to identify symptoms important and relevant to FD patients. A preliminary version of the FDSD was constructed, then completed by FD participants on an electronic device in cognitive interviews to evaluate the readability, comprehensibility, relevance, and comprehensiveness of the FDSD, and to preliminarily evaluate its measurement properties...
September 19, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28923491/readability-of-online-allergy-and-immunology-educational-resources-for-patients-implications-for-physicians
#5
Tudor Crihalmeanu, Arpan V Prabhu, David R Hansberry, Nitin Agarwal, Michael J Fine
No abstract text is available yet for this article.
September 8, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28905177/readability-assessment-of-online-patient-education-materials-provided-by-the-european-association-of-urology
#6
Patrick Betschart, Valentin Zumstein, Maico Bentivoglio, Daniel Engeler, Hans-Peter Schmid, Dominik Abt
PURPOSE: To assess the readability of the web-based patient education material provided by the European Association of Urology. MATERIALS AND METHODS: English patient education materials (PEM) as available in May 2017 were obtained from the EAU website. Each topic was analyzed separately using six well-established readability assessment tools, including Flesch-Kincaid Grade Level (FKGL), SMOG Grade Level (SMOG), Coleman-Liau Index (CLI), Gunning Fog Index (GFI), Flesch Reading Ease Formula (FRE) and Fry Readability Graph (FRG)...
September 13, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28899713/interrater-reliability-of-the-patient-education-materials-assessment-tool-pemat
#7
Julia Vishnevetsky, Chasity Burrows Walters, Kay See Tan
OBJECTIVE: To assess the interrater reliability (IRR) and usability of the Patient Education Materials Assessment Tool (PEMAT) and the relationship between PEMAT scores and readability levels. METHODS: One hundred ten materials (80 print, 30 audiovisual) were evaluated, each by two raters, using the PEMAT. IRR was calculated using Gwet's AC1 and summarized across items in each PEMAT domain (understandability and actionability) and by material type. A survey was conducted to solicit raters' experience using the PEMAT...
September 6, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28898465/polar-electrode-bridged-electroluminescent-displays-2d-sensors-remotely-communicating-optically
#8
Xiuru Xu, Dan Hu, Lijia Yan, Shaoli Fang, Clifton Shen, Yueh-Lin Loo, Yuan Lin, Carter S Haines, Na Li, Anvar A Zakhidov, Hong Meng, Ray H Baughman, Wei Huang
A novel geometry for electroluminescent devices, which does not require transparent electrodes for electrical input, is demonstrated, theoretically analyzed, and experimentally characterized. Instead of emitting light through a conventional electrode, light emission occurs through a polar liquid or solid and input electrical electrodes are coplanar, rather than stacked in a sandwich configuration. This new device concept is scalable and easily deployed for a range of modular alternating-current-powered electroluminescent light sources and light-emitting sensing devices...
September 12, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28892821/readability-level-of-spanish-language-patient-reported-outcome-measures-in-audiology-and-otolaryngology
#9
Laura Coco, Sonia Colina, Samuel R Atcherson, Nicole Marrone
Purpose: The purpose of this study was to examine the readability level of the Spanish versions of several audiology- and otolaryngology-related patient-reported outcome measures (PROMs) and include a readability analysis of 2 translation approaches when available-the published version and a "functionalist" version-using a team-based collaborative approach including community members. Method: Readability levels were calculated using the Fry Graph adapted for Spanish, as well as the Fernandez-Huerta and the Spaulding formulae for several commonly used audiology- and otolaryngology-related PROMs...
September 18, 2017: American Journal of Audiology
https://www.readbyqxmd.com/read/28885483/assessing-readability-and-reliability-of-online-patient-information-regarding-vestibular-schwannoma
#10
Harry Spiers, Nikul Amin, Raj Lakhani, Andrew J Martin, Parag M Patel
HYPOTHESIS: The aim of this study is to objectively assess the quality and readability of websites related to vestibular schwannomas. BACKGROUND: Patients are increasingly seeking information on confirmed or suspected diagnoses through the Internet. Clinicians are often concerned regarding the accuracy, quality, and readability of web-based sites. METHODS: Online information relating to vestibular schwannoma was searched using the three most popular search engines...
September 6, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28882320/judges-delivery-of-ground-rules-to-child-witnesses-in-australian-courts
#11
Becky Earhart, Sonja P Brubacher, Martine B Powell, Nina J Westera, Jane Goodman-Delahunty
Ground rules directions are given to children in forensic interviews to explain what is expected of them, and to reduce their tendency to acquiesce to erroneous or incomprehensible questions. Ground rules may also be necessary when children provide testimony in court. Drawing on research conducted for the Australian Royal Commission into Institutional Responses to Child Sexual Abuse, the present study examined the use of ground rules directions delivered in court in 52 trials by 24 presiding judges in three jurisdictions to 57 child complainants (aged 7-17...
September 4, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28873054/the-readability-of-scientific-texts-is-decreasing-over-time
#12
Pontus Plavén-Sigray, Granville James Matheson, Björn Christian Schiffler, William Hedley Thompson
Clarity and accuracy of reporting are fundamental to the scientific process. Readability formulas can estimate how difficult a text is to read. Here, in a corpus consisting of 709,577 abstracts published between 1881 and 2015 from 123 scientific journals, we show that the readability of science is steadily decreasing. Our analyses show that this trend is indicative of a growing use of general scientific jargon. These results are concerning for scientists and for the wider public, as they impact both the reproducibility and accessibility of research findings...
September 5, 2017: ELife
https://www.readbyqxmd.com/read/28872744/combining-orthogonal-chain-end-deprotections-and-thiol-maleimide-michael-coupling-engineering-discrete-oligomers-through-iterative-growth-strategy
#13
Zhihao Huang, Junfei Zhao, Zimu Wang, Fanying Meng, Kunshan Ding, Xiangqiang Pan, Nianchen Zhou, Xiaopeng Li, Zhengbiao Zhang, Xiulin Zhu
For the first time, we combined orthogonal maleimide and thiol deprotections together with thiol-maleimide coupling to synthesize discrete oligomers/macromolecules on gram scale with molecular weight up to 27.4 kDa (128mer, 7.9 g) via iterative exponential growth strategy with degree of polymerization (DP) at 2^n-1. By using the same chemistry, a "readable" sequence-defined oligomer and a discrete cyclic topology were also created. Furthermore, uniform dendrons were fabricated via either sequential growth (DP =〖 2〗^n-1) or double exponential dendrimer growth approach (DP =2^(2^n )-1) with significantly accelerated growth rate...
September 5, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28870259/rdfio-extending-semantic-mediawiki-for-interoperable-biomedical-data-management
#14
Samuel Lampa, Egon Willighagen, Pekka Kohonen, Ali King, Denny Vrandečić, Roland Grafström, Ola Spjuth
BACKGROUND: Biological sciences are characterised not only by an increasing amount but also the extreme complexity of its data. This stresses the need for efficient ways of integrating these data in a coherent description of biological systems. In many cases, biological data needs organization before integration. This is not seldom a collaborative effort, and it is thus important that tools for data integration support a collaborative way of working. Wiki systems with support for structured semantic data authoring, such as Semantic MediaWiki, provide a powerful solution for collaborative editing of data combined with machine-readability, so that data can be handled in an automated fashion in any downstream analyses...
September 4, 2017: Journal of Biomedical Semantics
https://www.readbyqxmd.com/read/28866954/are-patients-comprehending-a-critical-assessment-of-online-patient-educational-materials
#15
Thanh-Lan Bui, Catalina Silva-Hirschberg, Josefina Torres, April W Armstrong
PURPOSE: The primary aim of this study was to evaluate the readability, understandability, suitability, and actionability of online psoriasis patient educational materials. A secondary aim was to identify areas for improvement. MATERIALS AND METHODS: We conducted an evaluation study to assess online psoriasis patient educational materials from the American Academy of Dermatology and National Psoriasis Foundation available in July 2017. We used two validated assessment tools specific to online healthcare materials...
September 4, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28864099/dr-google-the-readability-and-accuracy-of-patient-education-websites-for-graves-disease-treatment
#16
Amanda C Purdy, Almoatazbellah Idriss, Susan Ahern, Elizabeth Lin, Dawn M Elfenbein
BACKGROUND: National guidelines emphasize the importance of incorporating patient preferences into the recommendations for the treatment of Graves' disease. Many patients use the Internet to obtain health information, and search results can affect their treatment decisions. This study compares the readability and accuracy of patient-oriented online resources for the treatment of Graves' disease by website affiliation and treatment modality. METHODS: A systematic Internet search was used to identify the top websites discussing the treatment of Graves' disease...
August 29, 2017: Surgery
https://www.readbyqxmd.com/read/28861021/reading-traits-for-dynamically-presented-texts-comparison-of-the-optimum-reading-rates-of-dynamic-text-presentation-and-the-reading-rates-of-static-text-presentation
#17
Miki Uetsuki, Junji Watanabe, Hideyuki Ando, Kazushi Maruya
With the growth in digital display technologies, dynamic text presentation is used widely in every day life, such as in electric advertisements and tickers on TV programs. Unlike static text reading, little is known about the basic characteristics underlying reading dynamically presented texts. Two experiments were performed to investigate this. Experiment 1 examined the optimum rate of dynamic text presentation in terms of a readability and favorability. This experiment demonstrated that, when the rate of text presentation was changed, there was an optimum presentation rate (around 6 letters/s in our condition) regardless of difficulty level...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28858881/online-patient-resources-for-gender-affirmation-surgery-an-analysis-of-readability
#18
Elizabeth Kiwanuka, Raman Mehrzad, Adnan Prsic, Daniel Kwan
BACKGROUND: Gender affirmation surgery is an important treatment for patient with gender dysphoria. It consists of a series of complex procedures, and well-informed patients have been shown to have better outcomes. However, there are no published data regarding the readability of currently available online patient recourses for gender affirmation surgery. This study aims at identifying the most popular online resources and evaluating the readability of these documents in the context of average literacy within the United States...
October 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28857969/assessing-online-patient-education-readability-for-spine-surgery-procedures
#19
William W Long, Krishna D Modi, Brittany E Haws, Benjamin Khechen, Dustin H Massel, Benjamin C Mayo, Kern Singh
BACKGROUND CONTEXT: Increased patient reliance on Internet-based health information has amplified the need for comprehensible online patient education articles. As suggested by the American Medical Association and National Institute of Health, spine fusion articles should be written for a 4th-6th-grade reading level to increase patient comprehension, which may improve postoperative outcomes. PURPOSE: The purpose of this study is to determine the readability of online health care education information relating to anterior cervical discectomy and fusion (ACDF) and lumbar fusion procedures...
August 28, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28856579/readability-of-informed-consent-forms-for-whole-exome-and-whole-genome-sequencing
#20
Emilia Niemiec, Danya F Vears, Pascal Borry, Heidi Carmen Howard
Whole-exome and whole-genome sequencing (WES, WGS) can generate an unprecedented amount of complex information, making the informed consent (IC) process challenging. The aim of our study was to assess the readability of English IC forms for clinical whole-exome and whole-genome sequencing using the SMOG and Flesch-Kincaid formulas. We analysed 36 forms, most of which were from US providers. The median readability grade levels were 14.75 (the SMOG formula) and 12.2 (the Flesch-Kincaid formula); these values indicate the years of education after which a person would be able to understand a text studied...
August 31, 2017: Journal of Community Genetics
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