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https://www.readbyqxmd.com/read/28086747/microrna-based-pan-cancer-diagnosis-and-treatment-recommendation
#1
Nikhil Cheerla, Olivier Gevaert
BACKGROUND: The current state-of-the-art in cancer diagnosis and treatment is not ideal; diagnostic tests are accurate but invasive, and treatments are "one-size fits-all" instead of being personalized. Recently, miRNA's have garnered significant attention as cancer biomarkers, owing to their ease of access (circulating miRNA in the blood) and stability. There have been many studies showing the effectiveness of miRNA data in diagnosing specific cancer types, but few studies explore the role of miRNA in predicting treatment outcome...
January 13, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28070842/diagnostic-imaging-and-spending-review-extreme-problems-call-for-extreme-measures
#2
Anna Micaela Ciarrapico, Rossana Ugenti, Lidia Di Minco, Elisabetta Santori, Simone Altobelli, Irene Coco, Silvia D'Onofrio, Giovanni Simonetti
The number of diagnostic imaging tests has increased dramatically over the past decade and about 5 billion diagnostic examinations are performed worldwide each year. According to Health Ministry, Italy, is in second place for the number of CT and MR tests per thousand inhabitants in 2014 with a score of 83.3 (only Germany has a higher score, 95.2) that is a long way off from the European average of 46.5. It has also the highest ratio of magnetic resonances per person with 24,6 machines per million inhabitants, followed only by Greece and Finland...
January 9, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28068172/access-to-accredited-cancer-hospitals-within-federal-exchange-plans-under-the-affordable-care-act
#3
Kenneth L Kehl, Kai-Ping Liao, Trudy M Krause, Sharon H Giordano
Purpose The Affordable Care Act expanded access to health insurance in the United States, but concerns have arisen about access to specialized cancer care within narrow provider networks. To characterize the scope and potential impact of this problem, we assessed rates of inclusion of Commission on Cancer (CoC) -accredited hospitals and National Cancer Institute (NCI) -designated cancer centers within federal exchange networks. Methods We downloaded publicly available machine-readable network data and public use files for individual federal exchange plans from the Centers for Medicare and Medicaid Services for the 2016 enrollment year...
January 9, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28062390/the-readability-of-electronic-cigarette-health-information-and-advice-a-quantitative-analysis-of-web-based-information
#4
Albert Park, Shu-Hong Zhu, Mike Conway
BACKGROUND: The popularity and use of electronic cigarettes (e-cigarettes) has increased across all demographic groups in recent years. However, little is currently known about the readability of health information and advice aimed at the general public regarding the use of e-cigarettes. OBJECTIVE: The objective of our study was to examine the readability of publicly available health information as well as advice on e-cigarettes. We compared information and advice available from US government agencies, nongovernment organizations, English speaking government agencies outside the United States, and for-profit entities...
January 6, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/28051899/serious-games-for-health-the-potential-of-metadata
#5
Stefan Göbel, Ralph Maddison
OBJECTIVE: Numerous serious games and health games exist, either as commercial products (typically with a focus on entertaining a broad user group) or smaller games and game prototypes, often resulting from research projects (typically tailored to a smaller user group with a specific health characteristic). A major drawback of existing health games is that they are not very well described and attributed with (machine-readable, quantitative, and qualitative) metadata such as the characterizing goal of the game, the target user group, or expected health effects well proven in scientific studies...
January 4, 2017: Games for Health
https://www.readbyqxmd.com/read/28045633/readability-trends-of-online-information-by-the-american-academy-of-otolaryngology-head-and-neck-surgery-foundation
#6
Kevin Wong, Jessica R Levi
Objective Previous studies have shown that patient education materials published by the American Academy of Otolaryngology-Head and Neck Surgery Foundation may be too difficult for the average reader to understand. The purpose of this study was to determine if current educational materials show improvements in readability. Study Design Cross-sectional analysis. Setting The Patient Health Information section of the American Academy of Otolaryngology-Head and Neck Surgery Foundation website. Subjects and Methods All patient education articles were extracted in plain text...
January 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28038475/readability-of-online-sources-regarding-meniscal-tears
#7
Jonathan D Hodax, Grayson L Baird, Trevor McBride, Brett D Owens
Meniscal injuries are extremely common, with an incidence of 8.3 per 1,000 person/years in young, active individuals. Patients often turn to the internet to glean information about their injuries, and even to guide decision making about treatment. Much research has been done demonstrating that a reading level of eighth grade or lower is appropriate for accurately communicating written information to patients, yet medical practitioners often fail to meet this requirement. To better examine the information patients receive about meniscal injuries, we set out to evaluate the reading level and content of three commonly used search terms on the three search engines with the largest market share...
December 30, 2016: Journal of Knee Surgery
https://www.readbyqxmd.com/read/28010914/reconstructions-using-rif-in-motion-mapping-technique-have-substantially-less-arrhythmogenic-artifacts-in-dual-source-coronary-cta
#8
Sebastian Daniel Reinartz, Markus Winkler, Sascha B Diefenbach, Thomas Allmendinger, Tobias Penzkofer, Christiane K Kuhl, Andreas H Mahnken
RATIONALE AND OBJECTIVES: Particularly for patients with heart arrhythmias, conventional BestSystole (BS) and BestDiastole (BD) reconstruction techniques in computed tomography (CT) frequently show artifacts that hinder the readability of the coronary tree. To address this problem, this paper presents an alternative reconstruction method that combines the technique "reconstructions with identical filling" (RIF) with motion mapping: This new technique is called "RIF in motion mapping" (RIMM)...
December 20, 2016: Academic Radiology
https://www.readbyqxmd.com/read/27992157/medicare-and-state-health-care-programs-fraud-and-abuse-revisions-to-the-office-of-inspector-general-s-civil-monetary-penalty-rules-final-rule
#9
(no author information available yet)
This final rule amends the civil monetary penalty (CMP or penalty) rules of the Office of Inspector General to incorporate new CMP authorities, clarify existing authorities, and reorganize regulations on civil money penalties, assessments, and exclusions to improve readability and clarity.
7, 2016: Federal Register
https://www.readbyqxmd.com/read/27990265/building-pathway-graphs-from-biopax-data-in-r
#10
Nirupama Benis, Dirkjan Schokker, Frank Kramer, Mari A Smits, Maria Suarez-Diez
Biological pathways are increasingly available in the BioPAX format which uses an RDF model for data storage. We can retrieve the information in this data model in the scripting language R using the package rBiopaxParser, which converts the BioPAX format to one readable in R. It also has a function to build a regulatory network from the pathway information, here we describe an extension of this function. The new function will also include non-regulatory interactions in the pathway and thus allow extraction of maximum information...
2016: F1000Research
https://www.readbyqxmd.com/read/27969464/mini01-16-not-so-easy-readability-assessment-of%C3%A2-patient-education-material-on-non-small-cell-lung-cancer-immunotherapy-topic-medical-oncology
#11
Supreet Kaur, Abhishek Kumar, Dhruv Mehta, Rashika Bansal, Anubha Arora, Michael Maroules
No abstract text is available yet for this article.
November 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27936670/simulation-based-algorithm-for-two-dimensional-chemical-structure-diagram-generation-of-complex-molecules-and-ligand-protein-interactions
#12
Tomasz Frączek
Computer programs for structure diagram generation (SDG) are indispensable cheminformatic tools that translate one- or three-dimensional (1D or 3D) chemical structure data stored in electronic formats to human-readable 2D depictions. Although many such programs are known, only a moderate part of chemical space can be handled by existing algorithms. For many classes of natural and synthetic compounds the results obtained with current SDG methods are illegible. A new algorithm based solely on a physical simulation of a molecule has been developed...
December 27, 2016: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/27932524/partial-tonsillectomy-content-and-readability-of-online-health-information
#13
Kevin Wong, Jessica R Levi
OBJECTIVES: Evaluate the content and readability of health information regarding partial tonsillectomy. METHODS: A web search was performed using the term partial tonsillectomy in Google, Yahoo!, and Bing. The first 50 websites from each search were evaluated using HONcode standards for quality and content. Readability was assessed using the Flesch-Kincaid Grade Level (FKGL), Flesch Reading Ease, Gunning-Fog Index, Coleman-Liau Index, Automated Readability Index, and SMOG score...
December 7, 2016: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/27931249/tailored-approach-to-sleep-health-education-tashe-study-protocol-for-a-web-based-randomized-controlled-trial
#14
Natasha J Williams, Rebecca Robbins, David Rapoport, John P Allegrante, Alwyn Cohall, Gbenga Ogedgebe, Girardin Jean-Louis
BACKGROUND: Obstructive sleep apnea (OSA) is a sleep disorder that disproportionately affects African Americans (hereafter referred to as blacks). Moreover, blacks may underutilize sleep services including overnight polysomnography. Thus, OSA among blacks may go undiagnosed and untreated, which has significant health consequences, including hypertension, diabetes, cognitive impairment, and daytime sleepiness. DESIGN AND METHODS: This two-arm randomized controlled trial will assign 200 participants to a culturally and linguistically tailored web-based sleep educational platform...
December 8, 2016: Trials
https://www.readbyqxmd.com/read/27925391/academic-poster-design-at-a-national-conference-a-need-for-standardised-guidance
#15
Alan Gopal, Melody Redman, David Cox, David Foreman, Elizabeth Elsey, Simon Fleming
BACKGROUND: Academic posters are a common means of disseminating information at conferences. Presentation at conferences is frequently given weight in postgraduate training programme recruitment. Some conferences provide guidance for visual presentation of posters. For the Association of the Study of Medical Education (ASME) Annual Scientific Meeting (ASM) 2015, poster abstract guidance was provided; however, the guidance on poster design was limited to size and orientation. The aim of this study was to investigate academic poster quality at a national medical education conference to identify where standards could be promoted and improved...
December 7, 2016: Clinical Teacher
https://www.readbyqxmd.com/read/27924368/a-quantitative-readability-analysis-of-patient-education-resources-from-gastroenterology-society-websites
#16
David R Hansberry, Sahil R Patel, Prateek Agarwal, Nitin Agarwal, Elizabeth S John, Ann M John, James C Reynolds
BACKGROUND AND AIMS: The lay public frequently access and rely on online information as a source of their medical knowledge. Many medical societies are unaware of national patient education material guidelines and subsequently fail to meet them. The goal of the present study was to evaluate the readability of patient education materials within the medical field of gastroenterology. METHODS: Two hundred fourteen articles pertaining to patient education materials were evaluated with ten well-established readability scales...
December 6, 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/27924347/preprocessing-structured-clinical-data-for-predictive-modeling-and-decision-support-a-roadmap-to-tackle-the-challenges
#17
José Carlos Ferrão, Mónica Duarte Oliveira, Filipe Janela, Henrique M G Martins
BACKGROUND: EHR systems have high potential to improve healthcare delivery and management. Although structured EHR data generates information in machine-readable formats, their use for decision support still poses technical challenges for researchers due to the need to preprocess and convert data into a matrix format. During our research, we observed that clinical informatics literature does not provide guidance for researchers on how to build this matrix while avoiding potential pitfalls...
December 7, 2016: Applied Clinical Informatics
https://www.readbyqxmd.com/read/27922621/sharing-brain-mapping-statistical-results-with-the-neuroimaging-data-model
#18
Camille Maumet, Tibor Auer, Alexander Bowring, Gang Chen, Samir Das, Guillaume Flandin, Satrajit Ghosh, Tristan Glatard, Krzysztof J Gorgolewski, Karl G Helmer, Mark Jenkinson, David B Keator, B Nolan Nichols, Jean-Baptiste Poline, Richard Reynolds, Vanessa Sochat, Jessica Turner, Thomas E Nichols
Only a tiny fraction of the data and metadata produced by an fMRI study is finally conveyed to the community. This lack of transparency not only hinders the reproducibility of neuroimaging results but also impairs future meta-analyses. In this work we introduce NIDM-Results, a format specification providing a machine-readable description of neuroimaging statistical results along with key image data summarising the experiment. NIDM-Results provides a unified representation of mass univariate analyses including a level of detail consistent with available best practices...
December 6, 2016: Scientific Data
https://www.readbyqxmd.com/read/27916381/readability-analysis-of-online-resources-related-to-lung-cancer
#19
Kathleen D Weiss, Christina R Vargas, Olivia A Ho, Danielle J Chuang, Jonathan Weiss, Bernard T Lee
BACKGROUND: Patients seeking health information commonly use the Internet as the first source for material. Studies show that well-informed patients have increased involvement, satisfaction, and healthcare outcomes. As one-third of Americans have only basic or below basic health literacy, the National Institutes of Health and American Medical Association recommend patient-directed health resources be written at a sixth-grade reading level. This study evaluates the readability of commonly accessed online resources on lung cancer...
November 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27914016/ms-ms-assisted-design-of-sequence-controlled-synthetic-polymers-for-improved-reading-of-encoded-information
#20
Laurence Charles, Gianni Cavallo, Valérie Monnier, Laurence Oswald, Roza Szweda, Jean-François Lutz
In order to improve their MS/MS sequencing, structure of sequence-controlled synthetic polymers can be optimized based on considerations regarding their fragmentation behavior in collision-induced dissociation conditions, as demonstrated here for two digitally encoded polymer families. In poly(triazole amide)s, the main dissociation route proceeded via cleavage of the amide bond in each monomer, hence allowing the chains to be safely sequenced. However, a competitive cleavage of an ether bond in a tri(ethylene glycol) spacer placed between each coding moiety complicated MS/MS spectra while not bringing new structural information...
December 2, 2016: Journal of the American Society for Mass Spectrometry
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