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https://www.readbyqxmd.com/read/29767625/correction-quantifying-the-contribution-of-plasmodium-falciparum-malaria-to-febrile-illness-amongst-african-children
#1
Ursula Dalrymple, Ewan Cameron, Samir Bhatt, Daniel J Weiss, Sunetra Gupta, Peter W Gething
No abstract text is available yet for this article.
May 16, 2018: ELife
https://www.readbyqxmd.com/read/29686725/prospective-observational-study-on-acute-appendicitis-worldwide-posaw
#2
Massimo Sartelli, Gian L Baiocchi, Salomone Di Saverio, Francesco Ferrara, Francesco M Labricciosa, Luca Ansaloni, Federico Coccolini, Deepak Vijayan, Ashraf Abbas, Hariscine K Abongwa, John Agboola, Adamu Ahmed, Lali Akhmeteli, Nezih Akkapulu, Seckin Akkucuk, Fatih Altintoprak, Aurelia L Andreiev, Dimitrios Anyfantakis, Boiko Atanasov, Miklosh Bala, Dimitrios Balalis, Oussama Baraket, Giovanni Bellanova, Marcelo Beltran, Renato Bessa Melo, Roberto Bini, Konstantinos Bouliaris, Daniele Brunelli, Adrian Castillo, Marco Catani, Asri Che Jusoh, Alain Chichom-Mefire, Gianfranco Cocorullo, Raul Coimbra, Elif Colak, Silvia Costa, Koray Das, Samir Delibegovic, Zaza Demetrashvili, Isidoro Di Carlo, Nadezda Kiseleva, Tamer El Zalabany, Mario Faro, Margarida Ferreira, Gustavo P Fraga, Mahir Gachabayov, Wagih M Ghnnam, Teresa Giménez Maurel, Georgios Gkiokas, Carlos A Gomes, Ewen Griffiths, Ali Guner, Sanjay Gupta, Andreas Hecker, Elcio S Hirano, Adrien Hodonou, Martin Hutan, Orestis Ioannidis, Arda Isik, Georgy Ivakhov, Sumita Jain, Mantas Jokubauskas, Aleksandar Karamarkovic, Saila Kauhanen, Robin Kaushik, Alfie Kavalakat, Jakub Kenig, Vladimir Khokha, Desmond Khor, Dennis Kim, Jae I Kim, Victor Kong, Konstantinos Lasithiotakis, Pedro Leão, Miguel Leon, Andrey Litvin, Varut Lohsiriwat, Eudaldo López-Tomassetti Fernandez, Eftychios Lostoridis, James Maciel, Piotr Major, Ana Dimova, Dimitrios Manatakis, Athanasio Marinis, Aleix Martinez-Perez, Sanjay Marwah, Michael McFarlane, Cristian Mesina, Michał Pędziwiatr, Nickos Michalopoulos, Evangelos Misiakos, Ali Mohamedahmed, Radu Moldovanu, Giulia Montori, Raghuveer Mysore Narayana, Ionut Negoi, Ioannis Nikolopoulos, Giuseppe Novelli, Viktors Novikovs, Iyiade Olaoye, Abdelkarim Omari, Carlos A Ordoñez, Mouaqit Ouadii, Zeynep Ozkan, Ajay Pal, Gian M Palini, Lars I Partecke, Francesco Pata, Michał Pędziwiatr, Gerson A Pereira Júnior, Tadeja Pintar, Magdalena Pisarska, Cesar F Ploneda-Valencia, Konstantinos Pouggouras, Vinod Prabhu, Padmakumar Ramakrishnapillai, Jean-Marc Regimbeau, Marianne Reitz, Daniel Rios-Cruz, Sten Saar, Boris Sakakushev, Charalampos Seretis, Alexander Sazhin, Vishal Shelat, Matej Skrovina, Dmitry Smirnov, Charalampos Spyropoulos, Marcin Strzałka, Peep Talving, Ricardo A Teixeira Gonsaga, George Theobald, Gia Tomadze, Myftar Torba, Cristian Tranà, Jan Ulrych, Mustafa Y Uzunoğlu, Alin Vasilescu, Savino Occhionorelli, Aurélien Venara, Andras Vereczkei, Nereo Vettoretto, Nutu Vlad, Maciej Walędziak, Tonguç U Yilmaz, Kuo-Ching Yuan, Cui Yunfeng, Justas Zilinskas, Gérard Grelpois, Fausto Catena
Background: Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis. The aim of this study is to describe the worldwide clinical and diagnostic work-up and management of AA in surgical departments. Methods: This prospective multicenter observational study was performed in 116 worldwide surgical departments from 44 countries over a 6-month period (April 1, 2016-September 30, 2016)...
2018: World Journal of Emergency Surgery: WJES
https://www.readbyqxmd.com/read/29667359/predicting-responses-to-mechanical-ventilation-for-preterm-infants-with-acute-respiratory-illness-using-artificial-neural-networks
#3
Katharine Brigham, Samir Gupta, John C Brigham
Infants born prematurely are particularly susceptible to respiratory illness due to underdeveloped lungs, which can often result in fatality. Preterm infants in acute stages of respiratory illness typically require mechanical ventilation assistance, and the efficacy of the type of mechanical ventilation and its delivery has been the subject of a number clinical studies. With recent advances in machine learning approaches, particularly deep learning, it may be possible to estimate future responses to mechanical ventilation in real-time, based on ventilation monitoring up to the point of analysis...
April 17, 2018: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/29602579/continued-uncertainty-regarding-treatment-of-patent-ductus-arteriosus-in-premature-infants-and-the-role-of-clinical-trials
#4
REVIEW
Edmund Juszczak, Samir Gupta
Despite several decades of research into treatments for patent ductus arteriosus (PDA), there is continued uncertainty regarding whether, when, and how best to treat PDA and the long-term consequences. There are almost 5000 babies enrolled into clinical trials, but the questions remain largely unanswered. Many of the trials performed over the period were well designed and addressed important clinical questions, but the results are not necessarily directly applicable to the clinical management dilemmas of today since perinatal care has improved over time per se, the patient population is typically more premature, and there have been technological advances in diagnosis...
March 7, 2018: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29571706/prophylactic-and-early-targeted-treatment-of-patent-ductus-arteriosus
#5
REVIEW
Jonathan P Wyllie, Samir Gupta
Treatment of a haemodynamically significant patent ductus arteriosus (PDA) in the very preterm infant has been an accepted approach for several decades. However, the rationale for closure of PDA has recently been challenged due to reports of success with conservative approaches and the lack of evidence for longer-term benefits from treatment. In this article, we address an approach to assess treatment of those babies most likely to benefit.
March 7, 2018: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29561293/long-term-kidney-function-proteinuria-and-associated-risks-among-hiv-infected-and-uninfected-men
#6
Frank Palella, Xiuhong Li, Samir K Gupta, Michelle M Estrella, John P Phair, Joseph B Margolick, Roger Detels, Lawrence Kingsley, Lisa P Jacobson
BACKGROUND: Factors affecting kidney function and proteinuria among HIV+ and HIV- persons need better characterization. METHODS: We evaluated estimated glomerular filtration rate (eGFR, mL/min per 1.73 m) changes, proteinuria prevalence (a urine protein-to-creatinine ratio [UPCr] of ≥0.2 at two consecutive visits) and associated factors among HIV+ and HIV- men. RESULTS: There were 917 HIV+ men receiving HAART, 159 HIV+ men not receiving HAART, and 1305 HIV- men seen from 10/2003 to 9/2014...
March 20, 2018: AIDS
https://www.readbyqxmd.com/read/29535472/clinical-practice-guideline-on-management-of-sleep-disorders-in-the-elderly
#7
Samir Kumar Praharaj, Ravi Gupta, Navendu Gaur
No abstract text is available yet for this article.
February 2018: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/29518628/aml-refractory-to-primary-induction-with-ida-flag-has-a-poor-clinical-outcome
#8
Simon Kavanagh, Emily Heath, Rose Hurren, Marcela Gronda, Samir H Barghout, Sanduni U Liyanage, Thirushi P Siriwardena, Jaime Claudio, Tong Zhang, Mahadeo Sukhai, Tracy L Stockley, Suzanne Kamel-Reid, Amr Rostom, Andrzej Lutynski, Dina Khalaf, Anna Rydlewski, Steven M Chan, Vikas Gupta, Dawn Maze, Hassan Sibai, Andre C Schuh, Karen Yee, Mark D Minden, Aaron D Schimmer
We evaluated outcomes of 100 patients with high risk AML treated with Ida-FLAG induction as first-line therapy. 72 achieved remission with one cycle; 19 did not. High risk cytogenetics and TP53 mutations were associated with failure to achieve remission. In those reaching remission, allogeneic bone marrow transplantation was associated with better relapse-free and overall survival. Those not achieving remission with induction therapy were extremely unlikely to reach remission with further therapy and had a dismal prognosis...
May 2018: Leukemia Research
https://www.readbyqxmd.com/read/29510135/overall-mortality-and-pancreatic-cancer-mortality-among-patients-with-pancreatic-cystic-neoplasms
#9
Gobind Anand, Fady Youssef, Samir Gupta
No abstract text is available yet for this article.
April 2018: Gastroenterology
https://www.readbyqxmd.com/read/29493547/divergent-effects-of-glucose-and-fructose-on-hepatic-lipogenesis-and-insulin-signaling
#10
Samir Softic, Manoj K Gupta, Guo-Xiao Wang, Shiho Fujisaka, Brian T O'Neill, Tata Nageswara Rao, Jennifer Willoughby, Carole Harbison, Kevin Fitzgerald, Olga Ilkayeva, Christopher B Newgard, David E Cohen, C Ronald Kahn
No abstract text is available yet for this article.
March 1, 2018: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/29483331/hepatopulmonary-syndrome
#11
Samir Gupta, Michael J Krowka
No abstract text is available yet for this article.
February 26, 2018: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/29477302/adherence-to-colorectal-cancer-screening-measured-as-the-proportion-of-time-covered
#12
Caitlin C Murphy, Bianca M Sigel, Edward Yang, Celette Sugg Skinner, Ethan A Halm, Samir Gupta, Joanne M Sanders, Katharine McCallister, Amit G Singal
BACKGROUND AND AIMS: Colorectal cancer (CRC) screening can reduce CRC incidence and mortality, but measuring screening adherence over time is challenging. We examined adherence using a novel measure characterizing the proportion of time covered (PTC) by screening tests. METHODS: Eligible patients were age 50 to 60 years and followed at a large, safety-net health care system between January 2010 and September 2014. We estimated PTC as the number of days up to date with screening divided by the number of days from cohort entry until study end, CRC diagnosis, or death...
February 23, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29463834/family-history-of-colorectal-cancer-in-first-degree-relatives-and-metachronous-colorectal-adenoma
#13
Elizabeth T Jacobs, Samir Gupta, John A Baron, Amanda J Cross, David A Lieberman, Gwen Murphy, María Elena Martínez
OBJECTIVES: Little is known about the relationship between having a first-degree relative (FDR) with colorectal cancer (CRC) and risk for metachronous colorectal adenoma (CRA) following polypectomy. METHODS: We pooled data from seven prospective studies of 7697 patients with previously resected CRAs to quantify the relationship between having a FDR with CRC and risk for metachronous adenoma. RESULTS: Compared with having no family history of CRC, a positive family history in any FDR was significantly associated with increased odds of developing any metachronous CRA (OR = 1...
February 20, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29323120/solving-the-mystery-of-the-yellow-zone-of-the-asthma-action-plan
#14
Samir Gupta, Alan Kaplan
No abstract text is available yet for this article.
January 11, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29223984/nccn-guidelines-insights-genetic-familial-high-risk-assessment-colorectal-version-3-2017
#15
Samir Gupta, Dawn Provenzale, Scott E Regenbogen, Heather Hampel, Thomas P Slavin, Michael J Hall, Xavier Llor, Daniel C Chung, Dennis J Ahnen, Travis Bray, Gregory Cooper, Dayna S Early, James M Ford, Francis M Giardiello, William Grady, Amy L Halverson, Stanley R Hamilton, Jason B Klapman, David W Larson, Audrey J Lazenby, Patrick M Lynch, Arnold J Markowitz, Robert J Mayer, Reid M Ness, Niloy Jewel Samadder, Moshe Shike, Shajanpeter Sugandha, Jennifer M Weiss, Mary A Dwyer, Ndiya Ogba
The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations for the management of patients with high-risk syndromes associated with an increased risk of colorectal cancer (CRC). The NCCN Panel for Genetic/Familial High-Risk Assessment: Colorectal meets at least annually to assess comments from reviewers within their institutions, examine relevant data, and reevaluate and update their recommendations. These NCCN Guidelines Insights focus on genes newly associated with CRC risk on multigene panels, the associated evidence, and currently recommended management strategies...
December 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/29198624/stereotactic-body-radiation-therapy-versus-surgery-for-early-lung-cancer-among-us-veterans
#16
Alex K Bryant, Robert C Mundt, Ajay P Sandhu, James J Urbanic, Andrew B Sharabi, Samir Gupta, Megan E Daly, James D Murphy
BACKGROUND: Stereotactic body radiation therapy (SBRT) has been proposed as a potential alternative to surgery for early lung cancer, although we lack well-powered prospective randomized data comparing these treatments, and existing studies suffer from incomplete information on confounders that can bias results. Here, we evaluated the comparative effectiveness of surgery and SBRT in lung cancer treatment using a large extensively detailed database from the Veteran's Affairs system. METHODS: We identified veterans with biopsy-proven clinical stage I non-small cell lung cancer diagnosed between 2006 and 2015 from within the Veteran's Affairs Informatics and Computing Infrastructure...
February 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29133258/when-should-patients-undergo-genetic-testing-for-hereditary-colon-cancer-syndromes
#17
Gregory Idos, Samir Gupta
No abstract text is available yet for this article.
February 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29133256/when-should-screening-stop-for-elderly-individuals-at-average-and-increased-risk-for-colorectal-cancer
#18
Folasade P May, Samir Gupta
No abstract text is available yet for this article.
February 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29119638/biphasic-papillary-renal-cell-carcinoma-is-a-rare-morphological-variant-with-frequent-multifocality-a-study-of-28-cases
#19
Kiril Trpkov, Daniel Athanazio, Cristina Magi-Galluzzi, Helene Yilmaz, David Clouston, Abbas Agaimy, Sean R Williamson, Fadi Brimo, Jose I Lopez, Monika Ulamec, Nathalie Rioux-Leclercq, Maysoun Kassem, Nilesh Gupta, Arndt Hartmann, Xavier Leroy, Samir Al Bashir, Asli Yilmaz, Ondřej Hes
AIMS: To further characterise biphasic squamoid renal cell carcinoma (RCC), a recently proposed variant of papillary RCC. METHODS AND RESULTS: We identified 28 tumours from multiple institutions. They typically showed two cell populations-larger cells with eosinophilic cytoplasm and higher-grade nuclei, surrounded by smaller, amphophilic cells with scanty cytoplasm. The dual morphology was variable (median 72.5% of tumour, range 5-100%); emperipolesis was found in all cases...
April 2018: Histopathology
https://www.readbyqxmd.com/read/29102276/effect-of-cd4-count-on-treatment-toxicity-and-tumor-recurrence-in-human-immunodeficiency-virus-positive-patients-with-anal-cancer
#20
Alex K Bryant, Ross Mudgway, Minh-Phuong Huynh-Le, Daniel R Simpson, Loren K Mell, Samir Gupta, Andrew B Sharabi, James D Murphy
PURPOSE: To study the effects of immunosuppression on treatment toxicity, long-term cancer recurrence risk, and survival among human immunodeficiency virus (HIV)-positive anal cancer patients. METHODS AND MATERIALS: From a nationwide retrospective cohort of veterans with anal cancer we identified 142 HIV-positive patients with stage I-III disease, diagnosed between 2000 and 2015 and treated with definitive-intent chemotherapy and radiation. We used regression models to study the impact of pretreatment CD4 counts and longitudinal posttreatment CD4 counts on outcomes including acute toxicity, long-term ostomy rates, cancer recurrence, cancer-specific survival, and overall survival...
February 1, 2018: International Journal of Radiation Oncology, Biology, Physics
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