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https://www.readbyqxmd.com/read/27915329/acute-kidney-injury-risk-assessment-and-the-nephrology-rapid-response-team
#1
Lilia Maria Rizo-Topete, Mitchell H Rosner, Claudio Ronco
Acute kidney Injury (AKI) is a serious medical condition affecting more than 10 million people around the world annually and resulting in poor outcomes. It has been suggested that late recognition of the syndrome may lead to delayed interventions with increased morbidity and mortality. Early diagnosis and timely therapeutic strategies may be the cornerstone of future improvement in outcomes. The purpose of this article is to provide a practical model to identify patients at high risk for AKI in different environments, with the goal to prevent AKI...
December 3, 2016: Blood Purification
https://www.readbyqxmd.com/read/27913561/hospitals-and-patients-working-in-unity-how-r-u-protocol-for-a-prospective-feasibility-study-of-telephone-peer-support-to-improve-older-patients-quality-of-life-after-emergency-department-discharge
#2
Judy A Lowthian, Alyse Lennox, Andrea Curtis, Jeremy Dale, Colette Browning, De Villiers Smit, Gillian Wilson, Debra O'Brien, Cate Rosewarne, Lee Boyd, Cath Garner, Peter Cameron
INTRODUCTION: Older people presenting to an emergency department (ED) have a higher likelihood of social isolation, loneliness and depression; which are all associated with negative health outcomes and increased health service use, including higher rates of ED attendance. The HOW R U? study aims to ascertain the feasibility and acceptability of a postdischarge telephone support programme for older ED patients following discharge. The intervention, which aims to improve quality of life, will be delivered by hospital-based volunteers...
December 2, 2016: BMJ Open
https://www.readbyqxmd.com/read/27913137/time-lapse-microscopy-patent-upheld-in-europe-response-to-pearce
#3
Sigrid Sterckx, Julian Cockbain, Guido Pennings
In this piece, we comment on the article by Pearce earlier in this journal. As Pearce correctly points out, what is fundamentally at issue in ESHRE et al's opposition to Stanford University's European patent on time-lapse microscopy is whether an exclusion from patentability, here of methods of medical diagnosis, should be interpreted narrowly or not. In the present case, the dominant piece of case law from the European Patent Office (EPO) gives a narrow interpretation of what a method of diagnosis must be in order not to be patentable...
November 16, 2016: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/27911062/-more-on-language-in-medical-journals
#4
EDITORIAL
C Jiménez Álvarez
No abstract text is available yet for this article.
January 25, 2016: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/27910291/acknowledging-the-peer-reviewers-of-journal-of-medical-radiation-sciences-october-2015-september-2016
#5
(no author information available yet)
No abstract text is available yet for this article.
December 2016: Journal of Medical Radiation Sciences
https://www.readbyqxmd.com/read/27909632/a-framework-for-navigating-institutional-review-board-irb-oversight-in-the-complicated-zone-of-research
#6
Gretchen E Parker
The treatment therapies and technologies currently emerging from the rapidly evolving health care industry must undergo full examination in a clinical setting if they are to be marketed to the public. All elements of clinical studies involving human subjects must undergo thorough IRB review before study activities can commence. Regulations regarding IRB oversight apply to all clinical studies-including retrospective examinations of private medical data and identifiable biological samples. It is not uncommon for researchers to be unsure whether, or on what level, IRB review and oversight are required for a particular project...
October 25, 2016: Curēus
https://www.readbyqxmd.com/read/27909034/advance-care-planning-in-patients-with-incurable-cancer-study-protocol-for-a-randomised-controlled-trial
#7
Stephanie Johnson, Josephine Clayton, Phyllis N Butow, William Silvester, Karen Detering, Jane Hall, Belinda E Kiely, Jonathon Cebon, Stephen Clarke, Melanie L Bell, Martin Stockler, Phillip Beale, Martin H N Tattersall
INTRODUCTION: There is limited evidence documenting the effectiveness of Advance Care Planning (ACP) in cancer care. The present randomised trial is designed to evaluate whether the administration of formal ACP improves compliance with patients' end-of-life (EOL) wishes and patient and family satisfaction with care. METHODS AND ANALYSIS: A randomised control trial in eight oncology centres across New South Wales and Victoria, Australia, is designed to assess the efficacy of a formal ACP intervention for patients with cancer...
December 1, 2016: BMJ Open
https://www.readbyqxmd.com/read/27906197/treatment-and-follow-up-of-venous-thrombosis-in-the-neonatal-intensive-care-unit-a-retrospective-study
#8
J C Bohnhoff, S A DiSilvio, R K Aneja, J R Shenk, Y A Domnina, B S Brozanski, M Good
OBJECTIVE: The critically ill, premature patients of neonatal intensive care units are susceptible to venous thrombosis, an adverse event associated with short- and long-term morbidity. Venous thrombosis is frequently treated with low-molecular-weight heparins (LMWHs) such as enoxaparin, but optimal dosing of LMWH must balance the morbidity of venous thrombosis with the potential adverse affects of anticoagulation. The optimal dosing of enoxaparin for premature infants is unclear. The objective of this study was to describe enoxaparin therapy and follow-up in critically ill neonates diagnosed with venous thrombosis...
December 1, 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/27905837/long-term-persistence-of-immunity-after-hepatitis-b-vaccination-a-fact-not-a-fancy
#9
Andrea Trevisan
On the basis of an article previously published in the journal regarding immune persistence after hepatitis B vaccination in infancy, I discuss why this persistence is a fact and not a fancy. Immune memory after a primary vaccination series has been widely demonstrated by prompt response to booster doses and the proliferation of T cells secreting IFNγ. In a large cohort of medical students, 79% of subjects were positive for anti-HBs antibodies, and only 1.9% of the subjects had serological evidence of past hepatitis B infection...
December 1, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27905331/prevalent-practice-patterns-in-glaucoma-poll-of-indian-ophthalmologists-at-a-national-conference
#10
Nikhil Shreeram Choudhari, Vanita Pathak-Ray, Sushmita Kaushik, Prateep Vyas, Ronnie George
PURPOSE: The aim of this study is to explore and compare the prevailing practice patterns in the diagnosis and management of glaucoma among subspecialists and general ophthalmologists in India. MATERIALS AND METHODS: This is an interactive audience response system (ARS) based poll of ophthalmologists attending the annual conference of the Glaucoma Society of India in 2013. RESULTS: The information was obtained from 379 ophthalmologists (146 glaucoma specialists, 54 nonglaucoma subspecialists, and 179 general ophthalmologists)...
October 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27904819/an-overview-of-compassionate-use-programs-in-the-european-union-member-states
#11
REVIEW
Gayathri Balasubramanian, Suman Morampudi, Pankdeep Chhabra, Arun Gowda, Behsad Zomorodi
The past decade witnessed rapid development of novel drugs and therapeutic biological agents. The marketing authorization for novel therapies is often time consuming and distressing for patients. Earlier clinical trials were the only way to access new drugs under development. However, not every patient meets the enrolment criteria, and participation is difficult for patients with life-threatening, long-lasting or seriously debilitating diseases like rare diseases. Early access programs like "Compassionate Use Program (CUP)" have generated alternative channels for such patients...
November 2016: Intractable & Rare Diseases Research
https://www.readbyqxmd.com/read/27904419/reporting-statistical-results-in-medical-journals
#12
EDITORIAL
Wan Nor Arifin, Abdullah Sarimah, Bachok Norsa'adah, Yaacob Najib Majdi, Ab Hamid Siti-Azrin, Musa Kamarul Imran, Abd Aziz Aniza, Lin Naing
Statistical editors of the Malaysian Journal of Medical Sciences (MJMS) must go through many submitted manuscripts, focusing on the statistical aspect of the manuscripts. However, the editors notice myriad styles of reporting the statistical results, which are not standardised among the authors. This could be due to the lack of clear written instructions on reporting statistics in the guidelines for authors. The aim of this editorial is to briefly outline reporting methods for several important and common statistical results...
September 2016: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/27903563/leveraging-ongoing-research-to-evaluate-the-health-impacts-of-south-africa-s-salt-reduction-strategy-a-prospective-nested-cohort-within-the-who-sage-multicountry-longitudinal-study
#13
Karen Charlton, Lisa J Ware, Elias Menyanu, Richard Berko Biritwum, Nirmala Naidoo, Chiné Pieterse, Savathree Lorna Madurai, Jeannine Baumgartner, George A Asare, Elizabeth Thiele, Aletta E Schutte, Paul Kowal
INTRODUCTION: Attempting to curb the rising epidemic of hypertension, South Africa implemented legislation in June 2016 mandating maximum sodium levels in a range of manufactured foods that contribute significantly to population salt intake. This natural experiment, comparing two African countries with and without salt legislation, will provide timely information on the impact of legislative approaches addressing the food supply to improve blood pressure in African populations. This article outlines the design of this ongoing prospective nested cohort study...
November 30, 2016: BMJ Open
https://www.readbyqxmd.com/read/27903561/keeping-weight-off-study-protocol-of-an-rct-to-investigate-brain-changes-associated-with-mindfulness-based-stress-reduction
#14
Carl Fulwiler, Julia A Siegel, Jeroan Allison, Milagros C Rosal, Judson Brewer, Jean A King
INTRODUCTION: Obesity is a growing epidemic fuelled by unhealthy behaviours and associated with significant comorbidities and financial costs. While behavioural interventions produce clinically meaningful weight loss, weight loss maintenance is challenging. This may partially be due to failure to target stress and emotional reactivity. Mindfulness-based stress reduction (MBSR) reduces stress and emotional reactivity and may be a useful tool for behaviour change maintenance. This study seeks to provide a mechanistic understanding for clinical trials of the benefits of MBSR for weight loss maintenance by examining changes in functional connectivity (FC) and the association of these changes with clinical outcomes...
November 30, 2016: BMJ Open
https://www.readbyqxmd.com/read/27902648/incidence-and-burden-of-pertussis-among-infants-less-than-1-year-of-age
#15
Cristina Masseria, Carolyn K Martin, Girishanthy Krishnarajah, Laura K Becker, Ami Buikema, Tina Q Tan
BACKGROUND: Infant-specific pertussis data, especially among neonates, are limited and variable. This study (NCT01890850) provides overall and age-specific pertussis incidence and associated healthcare utilization and costs among commercially insured infants in the United States. METHODS: Nearly 1.2 million infants born from 2005-2010 with commercial health plan coverage were followed during their first 12 months of life. Pertussis cases were identified from medical claims (ICD-9-CM 033...
November 28, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27902561/improving-retention-in-hiv-care-through-new-york-s-expanded-partner-services-data-to-care-pilot
#16
James M Tesoriero, Britney L Johnson, Rachel Hart-Malloy, Jennifer L Cukrovany, Brenda L Moncur, Kathleen M Bogucki, Bridget J Anderson, Megan C Johnson
CONTEXT: Data to Care (DTC) represents a public health strategy using HIV surveillance data to link persons living with diagnosed HIV infection (PLWDHI) to HIV-related medical care. OBJECTIVE: To investigate the feasibility of the DTC approach applied to a Partner Services program serving a geographically diffuse area of New York State. DESIGN: Disease intervention specialists received training to function as Expanded Partner Services (ExPS) advocates...
November 28, 2016: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/27901591/driving-restrictions-post-stroke-physicians-compliance-with-regulations
#17
Selina Mårdh, Pamela Mårdh, Anna Anund
Objective Suffering a stroke might lead to permanent cognitive and/or physical impairment. It has been shown that these impairments could have an impact on the individual's fitness to drive. In Sweden, as in many other countries, there are regulations on driving cessation post-stroke. The information on driving cessation should be given to all patients and noted in the journal. The present study sought to find out physician's compliance to driving regulations post-stroke as well as follow-up and gender aspects...
November 30, 2016: Traffic Injury Prevention
https://www.readbyqxmd.com/read/27900554/the-michel-benoist-and-robert-mulholland-yearly-european-spine-journal-review-a-survey-of-the-medical-articles-in-the-european-spine-journal-2016
#18
REVIEW
Michel Benoist
No abstract text is available yet for this article.
November 29, 2016: European Spine Journal
https://www.readbyqxmd.com/read/27900175/free-fall-acrobatics-to-reduce-neck-loads-during-parachute-opening-shock-evaluation-of-an-intervention-acropose
#19
Anton Westman, Björn O Äng
INTRODUCTION: Neck pain is a widespread health problem in the skydiver athlete population, epidemiologically linked to repeated exposure to parachute opening shock (POS). During POS, a parachutist is subjected to considerable deceleration forces. This study aims to evaluate the use of preventive free fall acrobatics to reduce the biomechanical load on the neck of parachutists during parachute opening. METHODS AND ANALYSIS: Interventional study with a cross-over, within-subject, repeated measures design...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27899400/study-protocol-a-phase-iii-randomised-double-blind-parallel-arm-stratified-block-randomised-placebo-controlled-trial-investigating-the-clinical-effect-and-cost-effectiveness-of-sertraline-for-the-palliative-relief-of-breathlessness-in-people-with-chronic-breathlessness
#20
Gareth J Watts, Katherine Clark, Meera Agar, Patricia M Davidson, Christine McDonald, Lawrence T Lam, Dimitar Sajkov, Nicola McCaffrey, Matthew Doogue, Amy P Abernethy, David C Currow
INTRODUCTION: Breathlessness remains a highly prevalent and distressing symptom for many patients with progressive life-limiting illnesses. Evidence-based interventions for chronic breathlessness are limited, and there is an ongoing need for high-quality research into developing management strategies for optimal palliation of this complex symptom. Previous studies have suggested that selective serotonin reuptake inhibitors such as sertraline may have a role in reducing breathlessness...
November 29, 2016: BMJ Open
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