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https://www.readbyqxmd.com/read/28526212/3d-deeply-supervised-network-for-automated-segmentation-of-volumetric-medical-images
#1
Qi Dou, Lequan Yu, Hao Chen, Yueming Jin, Xin Yang, Jing Qin, Pheng-Ann Heng
While deep convolutional neural networks (CNNs) have achieved remarkable success in 2D medical image segmentation, it is still a difficult task for CNNs to segment important organs or structures from 3D medical images owing to several mutually affected challenges, including the complicated anatomical environments in volumetric images, optimization difficulties of 3D networks and inadequacy of training samples. In this paper, we present a novel and efficient 3D fully convolutional network equipped with a 3D deep supervision mechanism to comprehensively address these challenges; we call it 3D DSN...
May 8, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28523852/preparing-adolescents-with-heart-problems-for-transition-to-adult-care-2009-2010-national-survey-of-children-with-special-health-care-needs
#2
Karrie F Downing, Matthew E Oster, Sherry L Farr
OBJECTIVE: A substantial percentage of children with congenital heart disease (CHD) fail to transfer to adult care, resulting in increased risk of morbidity and mortality. Transition planning discussions with a provider may increase rates of transfer, yet little is known about frequency and content of these discussions. We assessed prevalence and predictors of transition-related discussions between providers and parents of children with special healthcare needs (CSHCN) and heart problems, including CHD...
May 19, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28520881/sleep-apnea-disability-pension-and-cause-specific-mortality-a-nationwide-register-linkage-study
#3
Naja Hulvej Rod, Linnea Kjeldgård, Torbjörn Åkerstedt, Jane E Ferrie, Paula Salo, Jussi Vahtera, Kristina Alexanderson
Sleep apnea is a common problem affecting daily functioning and health. We evaluated associations between sleep apnea and disability pension and mortality in a prospective study of 74,543 cases of sleep apnea (60,125 outpatient; 14,418 inpatient) from the Swedish Patient Register; 2000-2009 inclusive. Cases were matched to five non-cases (n = 371,592) and followed from diagnosis/inclusion via nationwide registers until Dec 31 2010. During a mean (standard deviation) follow-up of 5.1 (2.7) years, 13% men and 21% women with inpatient sleep apnea were disability pensioned...
May 18, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28518119/analysis-of-cell-suspensions-isolated-from-solid-tissues-by-spectral-flow-cytometry
#4
Sandrine Schmutz, Mariana Valente, Ana Cumano, Sophie Novault
Flow cytometry has been used for the past 40 years to define and analyze the phenotype of lymphoid and other hematopoietic cells. Initially restricted to the analysis of a few fluorochromes, currently there are dozens of different fluorescent dyes, and up to 14-18 different dyes can be combined at a time. However, several limitations still impair the analytical capabilities. Because of the multiplicity of fluorescent probes, data analysis has become increasingly complex due to the need of large, multi-parametric compensation matrices...
May 5, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28515946/the-responses-of-subjective-feeling-task-performance-ability-cortisol-and-hrv-for-the-various-types-of-floor-impact-sound-a-pilot-study
#5
Seok Hyeon Yun, Sang Jin Park, Chang Sun Sim, Joo Hyun Sung, Ahra Kim, Jang Myeong Lee, Sang Hyun Lee, Jiho Lee
BACKGROUND: Recently, noise coming from the neighborhood via floor wall has become a great social problem. The noise between the floors can be a cause of physical and psychological problems, and the different types of floor impact sound (FIS) may have the different effects on the human's body and mind. The purpose of this study is to assess the responses of subjective feeling, task performance ability, cortisol and HRV for the various types of floor impact. METHODS: Ten men and 5 women were enrolled in our study, and the English listening test was performed under the twelve different types of FIS, which were made by the combinations of bang machine (B), tapping machine (T), impact ball (I) and sound-proof mattress (M)...
2017: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28515747/revascularization-in-ischemic-heart-failure-with-reduced-left-ventricular-ejection-fraction-the-impact-of-complete-revascularization
#6
Łukasz Pyka, Michał Hawranek, Mariusz Gąsior
Heart failure is a growing problem worldwide, with coronary artery disease being the underlying cause of over two-thirds of cases. Revascularization in this group of patients may potentially inhibit the progressive damage to the myocardium and lead to improved outcomes, but data in this area are scarce. This article emphasizes the role of qualification for revascularization and selection of method (percutaneous coronary intervention vs. coronary artery bypass grafting) and subsequently focuses on the issue of completeness of revascularization in this group of patients...
March 2017: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/28512434/evaluation-of-a-rapid-anisotropic-model-for-ecg-simulation
#7
Simone Pezzuto, Peter Kal'avský, Mark Potse, Frits W Prinzen, Angelo Auricchio, Rolf Krause
State-of-the-art cardiac electrophysiology models that are able to deliver physiologically motivated activation maps and electrocardiograms (ECGs) can only be solved on high-performance computing architectures. This makes it nearly impossible to adopt such models in clinical practice. ECG imaging tools typically rely on simplified models, but these neglect the anisotropic electric conductivity of the tissue in the forward problem. Moreover, their results are often confined to the heart-torso interface. We propose a forward model that fully accounts for the anisotropic tissue conductivity and produces the standard 12-lead ECG in a few seconds...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28511453/pregnancy-outcome-of-abnormal-nuchal-translucency-a-systematic-review
#8
Nasibeh Roozbeh, Maryam Azizi, Leili Darvish
INTRODUCTION: Nuchal Translucency (NT) is the sonographic form of subcutaneous gathering of liquid behind the foetal neck in the first trimester of pregnancy. There is association of increased NT with chromosomal and non-chromosomal abnormalities. AIM: The purpose of this systemic review was to review the pregnancy outcome of abnormal nuchal translucency. MATERIALS AND METHODS: The present systematic review was conducted by searching English language articles from sources such as International Medical Sciences, Medline, Web of science, Scopus, Google Scholar, PubMed, Index Copernicus, DOAJ, EBSCO-CINAHL...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28508958/modeling-the-critical-care-pathway-for-cardiothoracic-surgery
#9
Nicolas Bahou, Claire Fenwick, Gillian Anderson, Robert van der Meer, Tony Vassalos
The west of Scotland heart and lung center based at the Golden Jubilee National Hospital houses all adult cardiothoracic surgery for the region. Increased demand for scheduled patients and fluctuations in emergency referrals resulted in increasing waiting times and patient cancellations. The main issue was limited resources, which was aggravated by the stochastic nature of the length of stay (LOS) and arrival of patients. Discrete event simulation (DES) was used to assess if an enhanced schedule was sufficient, or more radical changes, such as capacity or other resource reallocations should be considered in order to solve the problem...
May 16, 2017: Health Care Management Science
https://www.readbyqxmd.com/read/28507239/pulsatile-flow-in-ventricular-catheters-for-hydrocephalus
#10
Á Giménez, M Galarza, U Thomale, M U Schuhmann, J Valero, J M Amigó
The obstruction of ventricular catheters (VCs) is a major problem in the standard treatment of hydrocephalus, the flow pattern of the cerebrospinal fluid (CSF) being one important factor thereof. As a first approach to this problem, some of the authors studied previously the CSF flow through VCs under time-independent boundary conditions by means of computational fluid dynamics in three-dimensional models. This allowed us to derive a few basic principles which led to designs with improved flow patterns regarding the obstruction problem...
June 28, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/28507167/early-activation-of-deleterious-molecular-pathways-in-the-kidney-in-experimental-heart-failure-with-atrial-remodeling
#11
Tomoko Ichiki, Brenda K Huntley, Gail J Harty, S Jeson Sangaralingham, John C Burnett
Heart failure (HF) is a major health problem with worsening outcomes when renal impairment is present. Therapeutics for early phase HF may be effective for cardiorenal protection, however the detailed characteristics of the kidney in early-stage HF (ES-HF), and therefore treatment for potential renal protection, are poorly defined. We sought to determine the gene and protein expression profiles of specific maladaptive pathways of ES-HF in the kidney and heart. Experimental canine ES-HF, characterized by de-novo HF with atrial remodeling but not ventricular fibrosis, was induced by right ventricular pacing for 10 days...
May 2017: Physiological Reports
https://www.readbyqxmd.com/read/28506147/long-term-outcome-after-survival-of-a-cardiac-arrest-a-prospective-longitudinal-cohort-study
#12
Véronique R M Moulaert, Caroline M van Heugten, Ton P M Gorgels, Derick T Wade, Jeanine A Verbunt
BACKGROUND: A cardiac arrest can lead to hypoxic brain injury, which can affect all levels of functioning. OBJECTIVE: To investigate 1-year outcome and the pattern of recovery after surviving a cardiac arrest. METHODS: This was a multicenter, prospective longitudinal cohort study with 1 year of follow-up (measurements 2 weeks, 3 months, 1 year). On function level, physical/cardiac function (New York Heart Association Classification), cognition (Cognitive Log [Cog-log], Cognitive Failures Questionnaire), emotional functioning (Hospital Anxiety and Depression Scale, Impact of Event Scale), and fatigue (Fatigue Severity Scale) were assessed...
June 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28505087/the-effect-of-diet-on-the-survival-of-patients-with-chronic-kidney-disease
#13
REVIEW
Jacek Rysz, Beata Franczyk, Aleksandra Ciałkowska-Rysz, Anna Gluba-Brzózka
The prevalence of chronic kidney disease (CKD) is high and it is gradually increasing. Individuals with CKD should introduce appropriate measures to hamper the progression of kidney function deterioration as well as prevent the development or progression of CKD-related diseases. A kidney-friendly diet may help to protect kidneys from further damage. Patients with kidney damage should limit the intake of certain foods to reduce the accumulation of unexcreted metabolic products and also to protect against hypertension, proteinuria and other heart and bone health problems...
May 13, 2017: Nutrients
https://www.readbyqxmd.com/read/28504921/plasminogen-activator-inhibitor-1-and-pericardial-fat-in-individuals-with-type-2-diabetes-mellitus
#14
Omar Bayomy, Ajay D Rao, Rajesh Garg, Anand Vaidya, Alyssa R Kotin, Beata Reiber, Stephanie Nijmeijer, Marcelo F Di Carli, Michael Jerosch-Herold, Raymond Y Kwong, Gail K Adler
BACKGROUND: Plasminogen activator inhibitor-1 (PAI-1) is implicated in the pathophysiology of cardiovascular disease (CVD) and increased in individuals with type 2 diabetes mellitus (T2DM). Adipose tissue produces PAI-1, and pericardial fat is a CVD risk factor. We sought to determine the relationship between PAI-1 and pericardial fat in males and females with well-controlled T2DM. METHODS: The study population consisted of 32 males and 19 females, aged 35-70 years with T2DM, without clinical evidence of CVD or other active medical problems except for hypertension...
May 15, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/28503975/body-image-after-heart-transplantation-compared-to-mechanical-aortic-valve-insertion
#15
Armin Hartmann, Claudia Heilmann, Josefine Kaps, Friedhelm Beyersdorf, Wolfgang Zeh, Wolfgang Albert, Michael Wirsching, Kurt Fritzsche, Andreas Joos
OBJECTIVE: Heart transplantation (HT) obviously affects body image and integrity. However, there are very few empirical data post-transplant. METHODS: In a cross-sectional study, 57 HT patients were compared with 47 subjects with mechanical aortic valve replacement (AVR) using the Dresden-Body-Image questionnaire (DKB) and specific questions regarding integration of the organ/device. In addition, affective symptoms and quality of life (QoL) were assessed (12-Item Short-Form Health Survey and Hospital Anxiety and Depression Scale, HADS)...
May 15, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/28502795/multi-scale-tailor-made-heart-simulation-can-predict-the-effect-of-cardiac-resynchronization-therapy
#16
Jun-Ichi Okada, Takumi Washio, Machiko Nakagawa, Masahiro Watanabe, Yoshimasa Kadooka, Taro Kariya, Hiroshi Yamashita, Yoko Yamada, Shin-Ichi Momomura, Ryozo Nagai, Toshiaki Hisada, Seiryo Sugiura
BACKGROUND: The currently proposed criteria for identifying patients who would benefit from cardiac resynchronization therapy (CRT) still need to be optimized. A multi-scale heart simulation capable of reproducing the electrophysiology and mechanics of a beating heart may help resolve this problem. The objective of this retrospective study was to test the capability of patient-specific simulation models to reproduce the response to CRT by applying the latest multi-scale heart simulation technology...
May 11, 2017: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/28499106/alcohol-and-cigarette-use-from-ages-23-to-55-links-with-health-and-well-being-in-the-long-term-national-child-development-study
#17
Jeremy Staff, Jennifer Maggs
OBJECTIVE: Using longitudinal data from the National Child Development Study, an ongoing study of a nationally representative British cohort born in 1958 (n = 9,137; 51% female), we examined how patterns of alcohol and cigarette use from young adulthood (age 23) to midlife (age 55) are associated with health and well-being. METHOD: We first used a nonparametric multilevel latent class specification to identify eight unique paths of alcohol and cigarette use from ages 23 to 55, and then assessed how these long-term latent paths related to overall health, heart problems, chronic illness, and quality of life at midlife...
May 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/28498910/extra-anatomical-bypass-in-complex-and-recurrent-aortic-coarctation-and-hypoplastic-arch%C3%A2
#18
Eva Maria Delmo Walter, Mariano Francisco Del Maria Javier, Roland Hetzer
OBJECTIVES: Our goal was to report the selection schemes, technical variations and long-term outcome of extra-anatomical bypass to correct complex, recurrent aortic coarctation and hypoplastic aortic arch. METHODS: Between 1989 and 2012, 53 patients (mean age 13.2 ± 4.3, median 11.6, range 9-23 years) with complex aortic coarctation ( n  = 33; long-segment hypoplastic aortic arch in 15), recurrent coarctation ( n  = 20; anastomosic pseudoaneurysm in 10), underwent correction using extra-anatomical bypass, either with ( n  = 18: femoral bypass = 13, left heart bypass = 5) or without ( n  = 35) extracorporeal circulation via a left lateral thoracotomy ( n = 48) and combined median sternotomy and median laparotomy ( n  = 5)...
May 11, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28497544/inducing-unconscious-stress-cardiovascular-activity-in-response-to-subliminal-presentation-of-threatening-and-neutral-words
#19
Melanie M van der Ploeg, Jos F Brosschot, Bart Verkuil, Brandon L Gillie, DeWayne P Williams, Julian Koenig, Michael W Vasey, Julian F Thayer
Stress-related cognitive processes may occur outside of awareness, here referred to as unconscious stress, and affect one's physiological state. Evidence supporting this idea would provide necessary clarification of the relationship between psychological stress and cardiovascular (CV) health problems. We tested the hypothesis that increases in mean arterial pressure (MAP) and total peripheral resistance (TPR) and decreases in heart rate variability (HRV) would be larger when threatening stimuli are presented outside of awareness, or subliminally, compared with neutral stimuli...
May 12, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28497088/pulmonary-hypertension-among-patients-undergoing-hemodialysis
#20
Fatemeh Hayati, Seyed Seifollah Beladi Mousavi, Seyed Majid Mousavi Movahed, Maryam Mofrad Bushehri
Introduction: The epidemiology of pulmonary hypertension (PHT) among long-term hemodialysis patients has been described in relatively small studies in Iran. Objectives: The purpose of this study was to evaluate the prevalence of PHT and its relationship among end-stage renal disease (ESRD) patients undergoing long-term hemodialysis (HD). Patients and Methods: In a cross-sectional study, patients with ESRD treated with HD for at least 3 months in the Imam hospital enrolled for the study. PHT was defined as an estimated systolic pulmonary artery pressure (PAP) equal to or higher than 25 mm Hg using echocardiograms performed by cardiologist...
2017: Journal of Renal Injury Prevention
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