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https://www.readbyqxmd.com/read/28430675/identifying-risk-factors-leading-to-unanticipated-postoperative-readmission
#1
Peter A Felice, David T Kerekes, Bruce A Mast
INTRODUCTION: Unanticipated postoperative readmissions are a grading metric directly linked to both the quality of patient care and physician reimbursement. However, little data exist to define factors responsible for these readmissions in the plastic surgery patient population. This study aims to identify patient risk factors contributing to unanticipated postoperative readmissions to optimize perioperative patient care and mitigate negative financial impact upon providers. METHODS: We present an institutional review board-approved study retrospective review of 819 plastic surgery patients undergoing operative procedures performed at our institution between January 1, 2013, and December 31, 2014...
April 20, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28428717/minimally-invasive-surgery-for-gastric-cancer-a-comparison-between-robotic-laparoscopic-and-open-surgery
#2
Amilcare Parisi, Daniel Reim, Felice Borghi, Ninh T Nguyen, Feng Qi, Andrea Coratti, Fabio Cianchi, Maurizio Cesari, Francesca Bazzocchi, Orhan Alimoglu, Johan Gagnière, Graziano Pernazza, Simone D'Imporzano, Yan-Bing Zhou, Juan-Santiago Azagra, Olivier Facy, Steven T Brower, Zhi-Wei Jiang, Lu Zang, Arda Isik, Alessandro Gemini, Stefano Trastulli, Alexander Novotny, Alessandra Marano, Tong Liu, Mario Annecchiarico, Benedetta Badii, Giacomo Arcuri, Andrea Avanzolini, Metin Leblebici, Denis Pezet, Shou-Gen Cao, Martine Goergen, Shu Zhang, Giorgio Palazzini, Vito D'Andrea, Jacopo Desiderio
AIM: To investigate the role of minimally invasive surgery for gastric cancer and determine surgical, clinical, and oncological outcomes. METHODS: This is a propensity score-matched case-control study, comparing three treatment arms: robotic gastrectomy (RG), laparoscopic gastrectomy (LG), open gastrectomy (OG). Data collection started after sharing a specific study protocol. Data were recorded through a tailored and protected web-based system. Primary outcomes: harvested lymph nodes, estimated blood loss, hospital stay, complications rate...
April 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28428679/mini-asymmetric-radial-keratotomy-and-corneal-cross-linking-for-the-treatment-of-a-bilateral-stage-iv-keratoconus-in-a-14-year-old-child
#3
Marco Abbondanza, Gabriele Abbondanza, Valentina De Felice
AIM: To present the case of a 14-year-old boy with bilateral stage IV keratoconus, treated with a combined MARK + CXL intervention, without the need for a corneal transplantation. RESULTS: The left eye displays considerable improvements, with a follow-up of 13.5 years: Kmax is decreased by 5.53 D, Kmed is decreased by 1.95 D and thinnest pachymetry is increased by 106 µm. The right eye shows equally remarkable parameters, with a follow-up of 9.5 years: Kmax is decreased by 8...
February 2017: Medical Archives
https://www.readbyqxmd.com/read/28427504/follow-up-program-in-head-and-neck-cancer
#4
REVIEW
Francesca De Felice, Marco de Vincentiis, Valentino Valentini, Daniela Musio, Silvia Mezi, Luigi Lo Mele, Valentina Terenzi, Vittorio D'Aguanno, Andrea Cassoni, Martina Di Brino, Gianluca Tenore, Nadia Bulzonetti, Andrea Battisti, Antonio Greco, Giorgio Pompa, Antonio Minni, Umberto Romeo, Enrico Cortesi, Antonella Polimeni, Vincenzo Tombolini
Follow-up program in head and neck cancer (HNC) is an important issue in patients management. It represents the major dilemma in daily practice clinic. Many guidelines have been published in order to better define the best clinical protocol, but a consensus has not been attained yet. We constructed a follow-up program based on specific primary subsite, to standardize patients surveillance after treatment of HNC.
May 2017: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/28424045/a-modified-mediterranean-dietary-intervention-for-adults-with-major-depression-dietary-protocol-and-feasibility-data-from-the-smiles-trial
#5
Rachelle S Opie, Adrienne O'Neil, Felice N Jacka, Josephine Pizzinga, Catherine Itsiopoulos
BACKGROUND: The SMILES trial was the first randomized controlled trial (RCT) explicitly designed to evaluate a dietary intervention, conducted by qualified dietitians, for reducing depressive symptomatology in adults with clinical depression. OBJECTIVES: Here we detail the development of the prescribed diet (modified Mediterranean diet (ModiMedDiet)) for individuals with major depressive disorders (MDDs) that was designed specifically for the SMILES trial. We also present data demonstrating the extent to which this intervention achieved improvements in diet quality...
April 19, 2017: Nutritional Neuroscience
https://www.readbyqxmd.com/read/28421052/whole-genome-based-amplified-fragment-length-polymorphism-analysis-reveals-genetic-diversity-in-candida-africana
#6
Anuradha Chowdhary, Ferry Hagen, Cheshta Sharma, Abdullah M S Al-Hatmi, Letterio Giuffrè, Domenico Giosa, Shangrong Fan, Hamid Badali, Maria Rosa Felice, Sybren de Hoog, Jacques F Meis, Orazio Romeo
This study aimed at investigating the genetic diversity of a panel of Candida africana strains recovered from vaginal samples in different countries. All fungal strains were heterozygous at the mating-type-like locus and belonged to the genotype A of Candida albicans. Moreover, all examined C. africana strains lack N-acetylglucosamine assimilation and sequence analysis of the HXK1 gene showed a distinctive polymorphism that impair the utilization of this amino sugar in this yeast. Multi-locus sequencing of seven housekeeping genes revealed a substantial genetic homogeneity among the strains, except for the CaMPIb, SYA1 and VPS13 loci which contributed significantly to the classification of our set of C...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28419212/pleurectomy-decortication-in-malignant-pleural-mesothelioma-are-different-surgical-techniques-associated-with-different-outcomes-results-from-a-multicentre-study%C3%A2
#7
Giuseppe Marulli, Cristiano Breda, Paolo Fontana, Giovanni Battista Ratto, Giacomo Leoncini, Marco Alloisio, Maurizio Infante, Luca Luzzi, Piero Paladini, Alberto Oliaro, Enrico Ruffini, Mauro Roberto Benvenuti, Gianluca Pariscenti, Lorenzo Spaggiari, Monica Casiraghi, Michele Rusca, Paolo Carbognani, Luca Ampollini, Francesco Facciolo, Giovanni Leuzzi, Felice Mucilli, Pierpaolo Camplese, Paola Romanello, Egle Perissinotto, Federico Rea
OBJECTIVES: The potential benefit of surgery for malignant pleural mesothelioma (MPM), especially concerning pleurectomy/decortication (P/D), is unclear from the literature. The aim of this study was to evaluate the outcome after multimodality treatment of MPM involving different types of P/D and to analyse the prognostic factors. METHODS: We reviewed 314 patients affected by MPM who were operated on in 11 Italian centres from 1 January 2007 to 11 October 2014. RESULTS: The characteristics of the population were male/female ratio: 3...
April 12, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28416513/what-is-broad-range-16s-rdna-pcr
#8
Amani Patel, Kathryn A Harris, Felicity Fitzgerald
No abstract text is available yet for this article.
April 17, 2017: Archives of Disease in Childhood. Education and Practice Edition
https://www.readbyqxmd.com/read/28416011/which-learning-activities-enhance-physiotherapy-practice-a-systematic-review-protocol-of-quantitative-and-qualitative-studies
#9
Edmund Leahy, Lucy Chipchase, Felicity Blackstock
BACKGROUND: Learning activities are fundamental for the development of expertise in physiotherapy practice. Continuing professional development (CPD) encompasses formal and informal learning activities undertaken by physiotherapists. Identifying the most efficient and effective learning activities is essential to enable the profession to assimilate research findings and improve clinical skills to ensure the most efficacious care for clients. To date, systematic reviews on the effectiveness of CPD provide limited guidance on the most efficacious models of professional development for physiotherapists...
April 17, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28414866/characterizing-the-outcomes-of-metastatic-papillary-renal-cell-carcinoma
#10
John Connor Wells, Frede Donskov, Anna P Fraccon, Felice Pasini, Georg A Bjarnason, Benoit Beuselinck, Jennifer J Knox, Sun Young Rha, Neeraj Agarwal, Isaac Alex Bowman, Jae-Lyun Lee, Sumanta K Pal, Sandy Srinivas, Douglas Scott Ernst, Ulka N Vaishampayan, Lori A Wood, Robin Simpson, Guillermo De Velasco, Toni K Choueiri, Daniel Y C Heng
Outcomes of metastatic papillary renal cell carcinoma (pRCC) patients are poorly characterized in the era of targeted therapy. A total of 5474 patients with metastatic renal cell carcinoma (mRCC) in the International mRCC Database Consortium (IMDC) were retrospectively analyzed. Outcomes were compared between clear cell (ccRCC; n = 5008) and papillary patients (n = 466), and recorded type I and type II papillary patients (n = 30 and n = 165, respectively). Overall survival (OS), progression-free survival (PFS), and overall response rate (ORR) favored ccRCC over pRCC...
April 16, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28414270/human-biallelic-mfn2-mutations-induce-mitochondrial-dysfunction-upper-body-adipose-hyperplasia-and-suppression-of-leptin-expression
#11
Nuno M Rocha, David A Bulger, Andrea Frontini, Hannah Titheradge, Sigrid Bjerge Gribsholt, Rachel Knox, Matthew Page, Julie Harris, Felicity Payne, Claire Adams, Alison Sleigh, John Crawford, Anette Prior Gjesing, Jette Bork-Jensen, Oluf Pedersen, Inês Barroso, Torben Hansen, Helen Cox, Mary Reilly, Alex Rossor, Rebecca J Brown, Simeon I Taylor, Duncan McHale, Martin Armstrong, Elif A Oral, Vladimir Saudek, Stephen I O'Rahilly, Eamonn R Maher, Bjørn Richelsen, David B Savage, Robert K Semple
MFN2 encodes mitofusin 2, a membrane-bound mediator of mitochondrial membrane fusion and inter-organelle communication. MFN2 mutations cause axonal neuropathy, with associated lipodystrophy only occasionally noted, however homozygosity for the p.Arg707Trp mutation was recently associated with upper body adipose overgrowth. We describe similar massive adipose overgrowth with suppressed leptin expression in four further patients with biallelic MFN2 mutations and at least one p.Arg707Trp allele. Overgrown tissue was composed of normal-sized, UCP1-negative unilocular adipocytes, with mitochondrial network fragmentation, disorganised cristae, and increased autophagosomes...
April 17, 2017: ELife
https://www.readbyqxmd.com/read/28412140/chronic-sleep-restriction-promotes-brain-inflammation-and-synapse-loss-and-potentiates-memory-impairment-induced-by-amyloid-%C3%AE-oligomers-in-mice
#12
Grasielle C Kincheski, Isabela S Valentim, Julia R Clarke, Danielle Cozachenco, Morgana T L Castelo-Branco, Angela M Ramos-Lobo, Vivian M B D Rumjanek, José Donato, Fernanda G De Felice, Sergio T Ferreira
It is increasingly recognized that sleep disturbances and Alzheimer's disease (AD) share a bidirectional relationship. AD patients exhibit sleep problems and alterations in the regulation of circadian rhythms; conversely, poor quality of sleep increases the risk of development of AD. The aim of the current study was to determine whether chronic sleep restriction potentiates the brain impact of amyloid-β oligomers (AβOs), toxins that build up in AD brains and are thought to underlie synapse damage and memory impairment...
April 13, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28411869/detection-of-endocrine-disrupting-chemicals-and-evidence-of-their-effects-on-the-hpg-axis-of-the-european-anchovy-engraulis-encrasicolus
#13
Andrea Miccoli, Francesca Maradonna, Andrea De Felice, Vincenzo Caputo Barucchi, Andone Estonba, Michele Genangeli, Sauro Vittori, Iole Leonori, Oliana Carnevali
Natural/synthetic Endocrine Disrupting Chemicals (EDCs) may display estrogenic activity and a lower potency than 17β-estradiol. Nonetheless, their concentrations and additive effects can affect the endocrine system and reproductive processes related to the Hypothalamic-Pituitary-Gonadal (HPG) axis. Because of their persistence in both the environment and biological systems, they ultimately target multi-level predators, including humans. We detected presence and effects of xenobiotics on wild anchovy Engraulis encrasicolus in the Western Adriatic Sea...
April 5, 2017: Marine Environmental Research
https://www.readbyqxmd.com/read/28411167/mast-cells-in-rheumatoid-arthritis-friends-or-foes
#14
REVIEW
Felice Rivellese, Alessandra Nerviani, Francesca Wanda Rossi, Gianni Marone, Marco Matucci-Cerinic, Amato de Paulis, Costantino Pitzalis
Mast cells are tissue-resident cells of the innate immunity, implicated in the pathogenesis of many autoimmune diseases, including rheumatoid arthritis (RA). They are present in synovia and their activation has been linked to the potentiation of inflammation in the course of RA. However, recent investigations questioned the role of mast cells in arthritis. In particular, animal models generated conflicting results, so that many of their pro-inflammatory, i.e. pro-arthritogenic functions, even though supported by robust experimental evidences, have been labelled as redundant...
April 11, 2017: Autoimmunity Reviews
https://www.readbyqxmd.com/read/28410344/preoperative-clostridium-difficile-infection-does-not-affect-pouch-outcomes-in-patients-with-ulcerative-colitis-who-undergo-ileal-pouch-anal-anastomosis
#15
Amy L Lightner, Chung Sang Tse, Kevin Quinn, John R Bergquist, Felicity Enders, Richard Pendegraft, Sahil Khanna, Laura Raffals
BACKGROUND: The operation of choice for patients with chronic ulcerative colitis (CUC) is restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA). Pouchitis is the most common complication after IPAA. The incidence of Clostridium difficile infection (CDI) is higher in CUC patients than the general population and can lead to significant disease flares and higher rates of colectomy. We sought to determine the risk of pouchitis in patients with precolectomy CDI and 90-day postoperative IPAA complications...
April 13, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28407529/resection-of-colorectal-liver-metastases-after-second-line-chemotherapy-is-it-worthwhile-a-livermetsurvey-analysis-of-6415-patients
#16
René Adam, Bin Yi, Pasquale F Innominato, Eduardo Barroso, Christophe Laurent, Felice Giuliante, Lorenzo Capussotti, Réal Lapointe, Jean-Marc Regimbeau, Santiago Lopez-Ben, Helena Isoniemi, Catherine Hubert, Jen-Kou Lin, Thomas Gruenberger, Dominique Elias, Oleg G Skipenko, Alfredo Guglielmi
PURPOSE: Patient outcome after resection of colorectal liver metastases (CLM) following second-line preoperative chemotherapy (PCT) performed for insufficient response or toxicity of the first-line, is little known and has here been compared to the outcome following first-line. PATIENTS AND METHODS: From January 2005 to June 2013, 5624 and 791 consecutive patients of a prospective international cohort received 1 and 2 PCT lines before CLM resection (group 1 and 2, respectively)...
April 10, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28405634/adolescents-with-idiopathic-scoliosis-and-their-parents-have-a-positive-attitude-towards-the-thermobrace-monitor-results-from-a-survey
#17
Sabrina Donzelli, Fabio Zaina, Gregorio Martinez, Francesca Di Felice, Alberto Negrini, Stefano Negrini
BACKGROUND: A temperature monitor is used to objectively measure brace wear time in adolescent idiopathic scoliosis. The reliability of this device have been demonstrated, and some specialists introduced the use of a compliance monitor as a standard of care in everyday clinical practice, as we did since 2010 with the Thermobrace (TB). The attitude towards these objective monitors has never been investigated. The present study aims to investigate the attitude of parents and patients towards the use of temperature sensors for measuring brace wear compliance...
2017: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/28399148/convergent-evolution-of-sws2-opsin-facilitates-adaptive-radiation-of-threespine-stickleback-into-different-light-environments
#18
David A Marques, John S Taylor, Felicity C Jones, Federica Di Palma, David M Kingsley, Thomas E Reimchen
Repeated adaptation to a new environment often leads to convergent phenotypic changes whose underlying genetic mechanisms are rarely known. Here, we study adaptation of color vision in threespine stickleback during the repeated postglacial colonization of clearwater and blackwater lakes in the Haida Gwaii archipelago. We use whole genomes from 16 clearwater and 12 blackwater populations, and a selection experiment, in which stickleback were transplanted from a blackwater lake into an uninhabited clearwater pond and resampled after 19 y to test for selection on cone opsin genes...
April 2017: PLoS Biology
https://www.readbyqxmd.com/read/28399032/recurrent-ovarian-cancer-the-role-of-radiation-therapy
#19
Francesca De Felice, Claudia Marchetti, Andrea Di Mino, Innocenza Palaia, Ilaria Benevento, Angela Musella, Daniela Musio, Vincenzo Tombolini
OBJECTIVE: The aim of this review was to present the current radiation therapy status in recurrent ovarian cancer (OC) and explore potential solution to improve clinical outcomes in this setting of patients. MATERIALS AND METHODS: PubMed search was performed. An attempt was made to include all relevant studies. Pertinent references cited in selected articles were also considered. RESULTS: The role of radiation therapy in recurrent OC needs to be defined...
April 8, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28398286/a-database-of-marine-phytoplankton-abundance-biomass-and-species-composition-in-australian-waters
#20
Claire H Davies, Alex Coughlan, Gustaaf Hallegraeff, Penelope Ajani, Linda Armbrecht, Natalia Atkins, Prudence Bonham, Steve Brett, Richard Brinkman, Michele Burford, Lesley Clementson, Peter Coad, Frank Coman, Diana Davies, Jocelyn Dela-Cruz, Michelle Devlin, Steven Edgar, Ruth Eriksen, Miles Furnas, Christel Hassler, David Hill, Michael Holmes, Tim Ingleton, Ian Jameson, Sophie C Leterme, Christian Lønborg, James McLaughlin, Felicity McEnnulty, A David McKinnon, Margaret Miller, Shauna Murray, Sasi Nayar, Renee Patten, Sarah A Pausina, Tim Pritchard, Roger Proctor, Diane Purcell-Meyerink, Eric Raes, David Rissik, Jason Ruszczyk, Anita Slotwinski, Kerrie M Swadling, Katherine Tattersall, Peter Thompson, Paul Thomson, Mark Tonks, Thomas W Trull, Julian Uribe-Palomino, Anya M Waite, Rouna Yauwenas, Anthony Zammit, Anthony J Richardson
No abstract text is available yet for this article.
April 11, 2017: Scientific Data
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