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Inger Agger

Inger Agger
After catastrophic events in which people's survival has been threatened, as happened during the Khmer Rouge regime in Cambodia 1975-1979, some continue to suffer from painful mental symptoms. Surveys carried out in Cambodia based on Western diagnostic categories have found a high prevalence of posttraumatic stress disorder (PTSD), depression, and anxiety symptoms in the population. This study explored Cambodian approaches to healing trauma, examining the ways in which Cambodians appeal to elements of Buddhism in their efforts to calm their minds, situating this mode of coping in the context of broader Khmer Buddhist practice and understandings...
August 2015: Transcultural Psychiatry
Soren T Hoff, Ahmed M Salman, Morten Ruhwald, Pernille Ravn, Inger Brock, Nabila Elsheikh, Peter Andersen, Else Marie Agger
BACKGROUND: The role of B cells in human host response to Mycobacterium tuberculosis (Mtb) infection is still controversial, but recent evidence suggest that B cell follicle like structures within the lung may influence host responses through regulation of the local cytokine environment. A candidate for such regulation could be the chemokine CXCL10. CXCL10 is mainly produced by human monocytes, but a few reports have also found CXCL10 production by human B cells. The objective of this study was to investigate CXCL10 production by human B cells in response to in vitro stimulation with Mtb antigens...
January 2015: Tuberculosis
Inger Agger, Victor Igreja, Rachel Kiehle, Peter Polatin
This study explores the therapeutic implications of including culturally adapted spiritual ceremonies in the process of testimonial therapy for torture survivors in India, Sri Lanka, Cambodia, and the Philippines. Data were collected through an action research process with Asian mental health and human rights organizations, during which the testimonial method was reconceptualized and modified to include four sessions. In the first two sessions, community workers assist survivors in the writing of their testimony, which is their narrative about the human rights violations they have suffered...
July 2012: Transcultural Psychiatry
Inger Agger, Lenin Raghuvanshi, Shirin Shabana, Peter Polatin, Laila K Laursen
INTRODUCTION: In developing countries where torture is perpetrated, there are few resources for the provision of therapeutic assistance to the survivors. The testimonial method represents a brief cross-cultural psychosocial approach to trauma, which is relatively easy to master. The method was first described in Chile in 1983 and has since been used in many variations in different cultural contexts. In this project the method has been supplemented by culture-specific coping strategies (meditation and a delivery ceremony)...
2009: Torture: Quarterly Journal on Rehabilitation of Torture Victims and Prevention of Torture
Morten Kobaek-Larsen, Axel Diederichsen, Ralf Agger, Inger Nissen, Marianne Hokland, Jesper Zeuthen, Jelmera Ritskes-Hoitinga
The aim of the present study was to characterise the local immune response in a chemically induced colon tumour model in the rat. Elucidating the character of the immune reaction may contribute to optimizing immunotherapeutic regimens for colon carcinoma in this model. Colon cancer was induced by four weekly subcutaneous azoxymethane injections in inbred rats of the BDIX/OrlIco strain in two separate studies. Azoxymethane-induced tumours show many similarities to spontaneously occurring human colon carcinomas with respect to histopathological appearance...
October 2004: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
Else Marie Agger, Inger Brock, Limei Meng Okkels, Sandra M Arend, Claus S Aagaard, Karin N Weldingh, Peter Andersen
In recent years, there has been considerable focus on the discovery and characterization of proteins derived from Mycobacterium tuberculosis leading to the identification of a number of candidate antigens for use in vaccine development or for diagnostic purposes. Previous experiments have demonstrated an important immunological role for proteins encoded by the RD1 region, which is absent from all strains of bacillus Calmette-Guérin (BCG) but present in the genomes of virulent M. bovis and M. tuberculosis. Herein, we have studied human T-cell responses to the antigen encoded by the putative open reading frame (rv3878) of the RD1 region...
December 2003: Immunology
Limei Meng Okkels, Inger Brock, Frank Follmann, Else Marie Agger, Sandra M Arend, Tom H M Ottenhoff, Fredrik Oftung, Ida Rosenkrands, Peter Andersen
Proteins encoded by DNA segment RD1 of Mycobacterium tuberculosis have recently been demonstrated to play important roles in bacterial virulence, vaccine development, and diagnostic reagent design. Previously, we characterized two immunodominant T-cell antigens, the early secreted antigen target (ESAT-6) and the 10-kDa culture filtrate protein (CFP10), which are encoded by the esx-lhp operon in this region. In the present study we characterized a third putative open reading frame in this region, rv3873, which encodes a PPE protein...
November 2003: Infection and Immunity
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