keyword
MENU ▼
Read by QxMD icon Read
search

Paul Bolton

keyword
https://www.readbyqxmd.com/read/28922778/circulating-folate-vitamin-b6-and-methionine-in-relation-to-lung-cancer-risk-in-the-lung-cancer-cohort-consortium-lc3
#1
Anouar Fanidi, David C Muller, Jian-Min Yuan, Victoria L Stevens, Stephanie J Weinstein, Demetrius Albanes, Ross Prentice, Cynthia A Thomsen, Mary Pettinger, Qiuyin Cai, William J Blot, Jie Wu, Alan A Arslan, Anne Zeleniuch-Jacquotte, Marjorie L McCullough, Loic Le Marchand, Lynne R Wilkens, Christopher A Haiman, Xuehong Zhang, Jiali Han, Meir J Stampfer, Stephanie A Smith-Warner, Edward Giovannucci, Graham G Giles, Allison M Hodge, Gianluca Severi, Mikael Johansson, Kjell Grankvist, Arnulf Langhammer, Steinar Krokstad, Marit Næss, Renwei Wang, Yu-Tang Gao, Lesley M Butler, Woon-Puay Koh, Xiao-Ou Shu, Yong-Bing Xiang, Honglan Li, Wei Zheng, Qing Lan, Kala Visvanathan, Judith Hoffman Bolton, Per Magne Ueland, Øivind Midttun, Arve Ulvik, Neil E Caporaso, Mark Purdue, Regina G Ziegler, Neal D Freedman, Julie E Buring, I-Min Lee, Howard D Sesso, J Michael Gaziano, Jonas Manjer, Ulrika Ericson, Caroline Relton, Paul Brennan, Mattias Johansson
Background: Circulating concentrations of B vitamins and factors related to one-carbon metabolism have been found to be strongly inversely associated with lung cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. The extent to which these associations are present in other study populations is unknown. Methods: Within 20 prospective cohorts from the National Cancer Institute Cohort Consortium, a nested case-control study was designed including 5364 incident lung cancer case patients and 5364 control subjects who were individually matched to case patients by age, sex, cohort, and smoking status...
January 1, 2018: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/28805679/controlling-blown-pack-spoilage-using-anti-microbial-packaging
#2
Rachael Reid, Declan Bolton, Andrey A Tiuftin, Joe P Kerry, Séamus Fanning, Paul Whyte
Active (anti-microbial) packaging was prepared using three different formulations; Auranta FV; Inbac-MDA and sodium octanoate at two concentrations (2.5 and 3.5 times their minimum inhibitory concentration (MIC, the lowest concentration that will inhibit the visible growth of the organisms) against Clostridium estertheticum, DSMZ 8809). Inoculated beef samples were packaged using the active packaging and monitored for 100 days storage at 2 °C for blown pack spoilage. The time to the onset of blown pack spoilage was significantly (p < 0...
August 12, 2017: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28800816/an-investigation-of-vtx2-bacteriophage-transduction-to-different-escherichia-coli-patho-groups-in-food-matrices-and-nutrient-broth
#3
Sepo Nyambe, Catherine Burgess, Paul Whyte, Declan Bolton
This study investigated bacteriophage (phage) mediated transfer of the vtx2 gene from a donor Escherichia coli (C600φ3538(Δvtx2::cat)) to enteropathogenic (EPEC), enterotoxigenic (ETEC), enteroaggregative (EAEC), enteroinvasive (EIEC) and diffusely adherent (DAEC) E. coli strains in LB broth, milk, ground beef and lettuce. Two bacterial concentrations for both the E. coli donor and recipient strains, 3 and 5 log10 CFU/ml (LB broth and milk)/g (beef) or/cm(2) (lettuce), were used. When transductants were obtained, the location of insertion of the phage (insertion sites wrbA, yehA, sbcB, yecE and/or Z2577) in the E...
December 2017: Food Microbiology
https://www.readbyqxmd.com/read/28728762/technology-to-support-motivational-interviewing
#4
Bonnie Gance-Cleveland, Loretta C Ford, Heather Aldrich, Keri Bolton Oetzel, Paul Cook, Sarah Schmiege, Mary Wold
PURPOSE: This paper reports the findings of motivational interviewing (MI) training with and without technology support on school-based health center (SBHC) providers' satisfaction with MI training, providers' self-report of behavioral counseling related to childhood overweight/obesity, and parents' perception of care after training. DESIGN AND METHODS: The effects of training and technology on MI is part of a larger comparative effectiveness, cluster randomized trial...
July 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28698032/beyond-infection-maternal-immune-activation-by-environmental-factors-microglial-development-and-relevance-for-autism-spectrum-disorders
#5
REVIEW
Staci D Bilbo, Carina L Block, Jessica L Bolton, Richa Hanamsagar, Phuong K Tran
Immune molecules such as cytokines and chemokines and the cells that produce them within the brain, notably microglia, are critical for normal brain development. This recognition has in recent years led to the working hypothesis that inflammatory events during pregnancy, e.g. in response to infection, may disrupt the normal expression of immune molecules during critical stages of neural development and thereby contribute to the risk for neurodevelopmental disorders such as autism spectrum disorder (ASD). This hypothesis has in large part been shepherded by the work of Dr...
July 8, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/28641137/real-time-pcr-methods-for-the-detection-of-blown-pack-spoilage-causing-clostridium-species-c-estertheticum-c-gasigenes-and-c-ruminantium
#6
Rachael Reid, Catherine M Burgess, Evonne McCabe, Séamus Fanning, Paul Whyte, Joe Kerry, Declan Bolton
A set of real-time PCR methods for the detection of C. estertheticum, C. gasigenes and C. ruminantium, the causative agents of blown pack spoilage (BPS) in vacuum packaged beef, was developed. Robust validation of the sensitivity and specificity was carried out in the three matrices (beef meat drip, wet environmental swabs and dry environmental swabs) as encountered in our testing laboratory and against Clostridium strains (n=76) and non-Clostridium strains (n=36). It was possible to detect 4-5 spores per ml for C...
June 3, 2017: Meat Science
https://www.readbyqxmd.com/read/28402869/the-use-of-composite-pulses-for-improving-deer-signal-at-94ghz
#7
Claire L Motion, Scott L Cassidy, Paul A S Cruickshank, Robert I Hunter, David R Bolton, Hassane El Mkami, Sabine Van Doorslaer, Janet E Lovett, Graham M Smith
The sensitivity of pulsed electron paramagnetic resonance (EPR) measurements on broad-line paramagnetic centers is often limited by the available excitation bandwidth. One way to increase excitation bandwidth is through the use of chirp or composite pulses. However, performance can be limited by cavity or detection bandwidth, which in commercial systems is typically 100-200MHz. Here we demonstrate in a 94GHz spectrometer, with >800MHz system bandwidth, an increase in signal and modulation depth in a 4-pulse DEER experiment through use of composite rather than rectangular π pulses...
May 2017: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/28334554/rapid-establishment-of-the-european-bank-for-induced-pluripotent-stem-cells-ebisc-the-hot-start-experience
#8
Paul A De Sousa, Rachel Steeg, Elisabeth Wachter, Kevin Bruce, Jason King, Marieke Hoeve, Shalinee Khadun, George McConnachie, Julie Holder, Andreas Kurtz, Stefanie Seltmann, Johannes Dewender, Sascha Reimann, Glyn Stacey, Orla O'Shea, Charlotte Chapman, Lyn Healy, Heiko Zimmermann, Bryan Bolton, Trisha Rawat, Isobel Atkin, Anna Veiga, Bernd Kuebler, Blanca Miranda Serano, Tomo Saric, Jürgen Hescheler, Oliver Brüstle, Michael Peitz, Cornelia Thiele, Niels Geijsen, Bjørn Holst, Christian Clausen, Majlinda Lako, Lyle Armstrong, Shailesh K Gupta, Alexander J Kvist, Ryan Hicks, Anna Jonebring, Gabriella Brolén, Andreas Ebneth, Alfredo Cabrera-Socorro, Patrik Foerch, Martine Geraerts, Tina C Stummann, Shawn Harmon, Carol George, Ian Streeter, Laura Clarke, Helen Parkinson, Peter W Harrison, Adam Faulconbridge, Luca Cherubin, Tony Burdett, Cesar Trigueros, Minal J Patel, Christa Lucas, Barry Hardy, Rok Predan, Joh Dokler, Maja Brajnik, Oliver Keminer, Ole Pless, Philip Gribbon, Carsten Claussen, Annette Ringwald, Beate Kreisel, Aidan Courtney, Timothy E Allsopp
A fast track "Hot Start" process was implemented to launch the European Bank for Induced Pluripotent Stem Cells (EBiSC) to provide early release of a range of established control and disease linked human induced pluripotent stem cell (hiPSC) lines. Established practice amongst consortium members was surveyed to arrive at harmonised and publically accessible Standard Operations Procedures (SOPs) for tissue procurement, bio-sample tracking, iPSC expansion, cryopreservation, qualification and distribution to the research community...
April 2017: Stem Cell Research
https://www.readbyqxmd.com/read/28245080/the-fate-of-verocytotoxigenic-escherichia-coli-c600%C3%AF-3538-%C3%AE-vtx2-cat-and-its-vtx2-prophage-during-grass-silage-preparation
#9
S Nyambe, C Burgess, P Whyte, P O'Kiely, D Bolton
AIMS: Silage is grass, preserved by fermentation and used as winter feed for cattle. The impact of a range of current grass silage preparation practices on the survival of Escherichia coli C600φ3538(Δvtx2 ::cat) and on the induction, release and infectivity of free phage were investigated. METHODS AND RESULTS: Wilted and fresh grass samples, from plots with and without slurry application, were ensiled with or without formic acid. Each treatment combination was inoculated with approximately 6 log10 CFU per g E...
May 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28163196/extraction-of-left-ventricular-ejection-fraction-information-from-various-types-of-clinical-reports
#10
Youngjun Kim, Jennifer H Garvin, Mary K Goldstein, Tammy S Hwang, Andrew Redd, Dan Bolton, Paul A Heidenreich, Stéphane M Meystre
Efforts to improve the treatment of congestive heart failure, a common and serious medical condition, include the use of quality measures to assess guideline-concordant care. The goal of this study is to identify left ventricular ejection fraction (LVEF) information from various types of clinical notes, and to then use this information for heart failure quality measurement. We analyzed the annotation differences between a new corpus of clinical notes from the Echocardiography, Radiology, and Text Integrated Utility package and other corpora annotated for natural language processing (NLP) research in the Department of Veterans Affairs...
March 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28077613/socioeconomic-deprivation-and-the-outcome-of-pulmonary-rehabilitation-in-england-and-wales
#11
Michael C Steiner, Derek Lowe, Katy Beckford, John Blakey, Charlotte E Bolton, Sarah Elkin, William D-C Man, C Michael Roberts, Louise Sewell, Paul Walker, Sally J Singh
BACKGROUND: Pulmonary rehabilitation (PR) improves exercise capacity and health status in patients with COPD, but many patients assessed for PR do not complete therapy. It is unknown whether socioeconomic deprivation associates with rates of completion of PR or the magnitude of clinical benefits bequeathed by PR. METHODS: PR services across England and Wales enrolled patients to the National PR audit in 2015. Deprivation was assessed using Index of Multiple Deprivation (IMD) derived from postcodes...
June 2017: Thorax
https://www.readbyqxmd.com/read/28075157/visual-occlusion-during-minimally-invasive-surgery-a-contemporary-review-of-methods-to-reduce-laparoscopic-and-robotic-lens-fogging-and-other-sources-of-optical-loss
#12
REVIEW
Todd G Manning, Marlon Perera, Daniel Christidis, Ned Kinnear, Shannon McGrath, Richard O'Beirne, Paul Zotov, Damien Bolton, Nathan Lawrentschuk
BACKGROUND: Maintenance of optimal vision during minimally invasive surgery is crucial to maintaining operative awareness, efficiency, and safety. Hampered vision is commonly caused by laparoscopic lens fogging (LLF), which has prompted the development of various antifogging fluids and warming devices. However, limited comparative evidence exists in contemporary literature. Despite technologic advancements there remains no consensus as to superior methods to prevent LLF or restore visual acuity once LLF has occurred...
April 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28067867/germline-brca2-mutations-drive-prostate-cancers-with-distinct-evolutionary-trajectories
#13
Renea A Taylor, Michael Fraser, Julie Livingstone, Shadrielle Melijah G Espiritu, Heather Thorne, Vincent Huang, Winnie Lo, Yu-Jia Shiah, Takafumi N Yamaguchi, Ania Sliwinski, Sheri Horsburgh, Alice Meng, Lawrence E Heisler, Nancy Yu, Fouad Yousif, Melissa Papargiris, Mitchell G Lawrence, Lee Timms, Declan G Murphy, Mark Frydenberg, Julia F Hopkins, Damien Bolton, David Clouston, John D McPherson, Theodorus van der Kwast, Paul C Boutros, Gail P Risbridger, Robert G Bristow
Germline mutations in the BRCA2 tumour suppressor are associated with both an increased lifetime risk of developing prostate cancer (PCa) and increased risk of aggressive disease. To understand this aggression, here we profile the genomes and methylomes of localized PCa from 14 carriers of deleterious germline BRCA2 mutations (BRCA2-mutant PCa). We show that BRCA2-mutant PCa harbour increased genomic instability and a mutational profile that more closely resembles metastastic than localized disease. BRCA2-mutant PCa shows genomic and epigenomic dysregulation of the MED12L/MED12 axis, which is frequently dysregulated in metastatic castration-resistant prostate cancer (mCRPC)...
January 9, 2017: Nature Communications
https://www.readbyqxmd.com/read/28038402/the-fate-of-salmonella-typhimurium-and-escherichia-coli-o157-on-hot-boned-versus-conventionally-chilled-beef
#14
Rachael Reid, Séamus Fanning, Paul Whyte, Joe Kerry, Declan Bolton
This study investigated the fate of Salmonella Typhimurium and Escherichia coli O157 on hot boned versus conventionally chilled beef. Beef samples were individually inoculated with S. Typhimurium ATCC 14028, S. Typhimurium 844, E. coli O157 EDL 933 or E. coli T13. Half the samples were subject to the same time-temperature chilling profile used for conventionally chilling beef carcasses while the other half was subject to hot boned conditions. The surface pH (5.5) and aw (0.95 to 0.97) were stable. S. Typhimurium and E...
April 2017: Meat Science
https://www.readbyqxmd.com/read/27981595/an-investigation-of-the-effect-of-rapid-slurry-chilling-on-blown-pack-spoilage-of-vacuum-packaged-beef-primals
#15
R Reid, S Fanning, P Whyte, J Kerry, D Bolton
The aim of this study was to investigate if rapid slurry chilling would retard or prevent blown pack spoilage (BPS) of vacuum-packaged beef primals. Beef primals were inoculated with Clostridium estertheticum subspp. estertheticum (DSMZ 8809), C. estertheticum subspp. laramenise (DSMZ 14864) and C. gasigenes (DSMZ 12272), and vacuum-packaged with and without heat shrinkage (90°C for 3 s). These packs were then subjected to immediate chilling in an ice slurry or using conventional blast chilling systems and stored at 2°C for up to 100 days...
February 2017: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/27886641/comparison-of-hot-versus-cold-boning-of-beef-carcasses-on-bacterial-growth-and-the-risk-of-blown-pack-spoilage
#16
COMPARATIVE STUDY
Rachael Reid, Séamus Fanning, Paul Whyte, Joe Kerry, Declan Bolton
Primals were prepared from beef Longissimus thoracis et lumborum (LTL), psoas major (PM), quadriceps femoris (QF) and semitendinosus (S) muscles from cold and hot boned carcasses, vacuum-packaged and stored for 42 or 100days at 2°C and 7°C. Storage temperature, carcass or primal surface temperature, pH and aw were monitored. Samples were taken periodically and tested for total viable count mesophilic (TVCm), TVC psychrophilic (TVCp), total Enterobacteriaceae count (TEC), presumptive Pseudomonas spp., lactic acid bacteria (LAB), Clostridium spp...
March 2017: Meat Science
https://www.readbyqxmd.com/read/27857003/mental-health-interventions-and-priorities-for-research-for-adult-survivors-of-torture-and-systematic-violence-a-review-of-the-literature
#17
REVIEW
William M Weiss, Ana M Ugueto, Zayan Mahmooth, Laura K Murray, Brian J Hall, Maya Nadison, Andrew Rasmussen, Jennifer S Lee, Andrea Vazzano, Judy Bass, Paul Bolton
This research describes the development and findings of a literature review and analysis meant to inform the international torture and trauma treatment community. The review focuses on interventions that have been used among populations affected by torture, based on a review of journals indexed in commonly used search engines. Work on the review began in September 2008 and continued to be updated until March 2014. In total, 88 studies of interventions for torture victims were identified. Studies ranged from randomized controlled trials utilizing evidence-based treatments to case studies employing non-structured, supportive therapies...
2016: Torture: Quarterly Journal on Rehabilitation of Torture Victims and Prevention of Torture
https://www.readbyqxmd.com/read/27697169/the-microbiology-of-beef-carcasses-and-primals-during-chilling-and-commercial-storage
#18
Rachael Reid, Séamus Fanning, Paul Whyte, Joe Kerry, Roland Lindqvist, Zhongyi Yu, Declan Bolton
The primary objective of this study was to characterise (microbiology and physical parameters) beef carcasses and primals during chilled storage. A minor aim was to compare observed growth of key spoilage bacteria on carcasses with that predicted by ComBase and the Food Safety Spoilage Predictor (FSSP). Total viable count (TVC), total Enterobacteriacae count (TEC), Pseudomonas spp., lactic acid bacteria (LAB), Brochothrix thermosphacta and Clostridium spp. were monitored on beef carcasses (n = 30) and primals (n = 105) during chilled storage using EC Decision 2001/471/EC and ISO sampling/laboratory procedures...
February 2017: Food Microbiology
https://www.readbyqxmd.com/read/27670638/quantifying-full-phenological-event-distributions-reveals-simultaneous-advances-temporal-stability-and-delays-in-spring-and-autumn-migration-timing-in-long-distance-migratory-birds
#19
Will T S Miles, Mark Bolton, Peter Davis, Roy Dennis, Roger Broad, Iain Robertson, Nick J Riddiford, Paul V Harvey, Roger Riddington, Deryk N Shaw, David Parnaby, Jane M Reid
Phenological changes in key seasonally expressed life-history traits occurring across periods of climatic and environmental change can cause temporal mismatches between interacting species, and thereby impact population and community dynamics. However, studies quantifying long-term phenological changes have commonly only measured variation occurring in spring, measured as the first or mean dates on which focal traits or events were observed. Few studies have considered seasonally paired events spanning spring and autumn or tested the key assumption that single convenient metrics accurately capture entire event distributions...
September 27, 2016: Global Change Biology
https://www.readbyqxmd.com/read/27647052/moderators-of-treatment-response-to-trauma-focused-cognitive-behavioral-therapy-among-youth-in-zambia
#20
Jeremy C Kane, Laura K Murray, Judith Cohen, Shannon Dorsey, Stephanie Skavenski van Wyk, Jennica Galloway Henderson, Mwiya Imasiku, John Mayeya, Paul Bolton
BACKGROUND: The effectiveness of mental health interventions such as trauma-focused cognitive behavioral therapy (TF-CBT) may vary by client, caregiver, and intervention-level variables, but few randomized trials in low- and middle-income countries (LMIC) have conducted moderation analyses to investigate these characteristics. This study explores moderating factors to TF-CBT treatment response among a sample of orphans and vulnerable children (OVC) in Zambia. METHODS: Data were obtained from a completed randomized trial of TF-CBT among 257 OVC in Zambia...
October 2016: Journal of Child Psychology and Psychiatry, and Allied Disciplines
keyword
keyword
70615
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"