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https://www.readbyqxmd.com/read/28818476/complex-anatomic-abnormalities-of-the-lower-leg-muscles-and-tendons-associated-with-phocomelia-a-case-report
#1
Thomas Hodo, Mark Hamrick, Yulia Melenevsky
Musculoskeletal anatomy is widely known to have components that stray from the norm in the form of variant muscle and tendon presence, absence, origin, insertion, and bifurcation. Although these variant muscles and tendons might be deemed incidental and insignificant findings by most, they can be important contributors to pathologic physiology or, more importantly, an option for effective treatment. In the present case report, we describe a patient with phocomelia and Müllerian abnormalities secondary to in utero thalidomide exposure...
August 14, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28814014/bio-inspired-control-of-joint-torque-and-knee-stiffness-in-a-robotic-lower-limb-exoskeleton-using-a-central-pattern-generator
#2
Stefan O Sobrade, Yannik Nager, Amy R Wu, Roger Gassert, Auke Ijspeert
Robotic lower limb exoskeletons are becoming increasingly popular in therapy and recreational use. However, most exoskeletons are still rather limited in their locomotion speed and the activities of daily live they can perform. Furthermore, they typically do not allow for a dynamic adaptation to the environment, as they are often controlled with predefined reference trajectories. Inspired by human leg stiffness modulation during walking, variable stiffness actuators increase flexibility without the need for more complex controllers...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813862/on-the-stiffness-analysis-of-a-cable-driven-leg-exoskeleton
#3
N S S Sanjeevi, Vineet Vashista
Robotic systems are being used for gait rehabilitation of patients with neurological disorder. These devices are externally powered to apply external forces on human limbs to assist the leg motion. Patients while walking with these devices adapt their walking pattern in response to the applied forces. The efficacy of a rehabilitation paradigm thus depends on the human-robot interaction. A cable driven leg exoskeleton (CDLE) use actuated cables to apply external joint torques on human leg. Cables are lightweight and flexible but can only be pulled, thus a CDLE requires redundant cables...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28806708/predictive-simulation-of-diabetic-gait-individual-contribution-of-ankle-stiffness-and-muscle-weakening
#4
Gilmar F Santos, Aline A Gomes, Isabel C N Sacco, Marko Ackermann
Diabetic neuropathic individuals present massive muscle strength reduction at the ankle plantar- and dorsiflexors and increased joint stiffness. Our aim is to investigate the adaptation strategies to these musculoskeletal alterations during walking by means of predictive simulations. We used a seven segment planar musculoskeletal model actuated by eight Hill-type muscles in each leg. The effect of all passive tissue in muscles and other joint structures was modeled by net passive joint moment curves. The predictive simulations were generated by solving an optimal control problem that minimized a cost function, including effort and tracking terms, using direct collocation and a commercial optimal control package...
August 1, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28801956/evidence-of-er-stress-and-upr-activation-in-patients-with-brody-disease-and-brody-syndrome
#5
V Guglielmi, N C Voermans, A Oosterhof, D Nowis, B G van Engelen, G Tomelleri, G Vattemi
Brody disease (BD, OMIM #601003) is an inherited skeletal muscle disease clinically characterized by exercise-induced impairment of muscle relaxation and stiffness due to the delay in the Ca(2+) re-uptake in the sarcoplasmic reticulum (SR)[1, 2]. The delayed muscle relaxation mainly affects legs, harms, hands and eyelids and usually improves after a few minutes rest [1-3]. Patients frequently report myalgia, painless or mildly painful cramps whereas recurrent rhabdomyolysis have been described in a few cases [2, 3]...
August 12, 2017: Neuropathology and Applied Neurobiology
https://www.readbyqxmd.com/read/28746246/acute-effects-of-constant-angle-and-constant-torque-static-stretching-on-passive-stiffness-of-the-posterior-hip-and-thigh-muscles-in-healthy-young-and-old-men
#6
Ty B Palmer
The purpose of this study was to examine the acute effects of constant-angle (CA) and constant-torque (CT) static stretching on passive stiffness of the posterior hip and thigh muscles in healthy, young and old men. Fifteen young (25±3 years) and 15 old (71±4 years) men underwent 2 passive straight-leg raise (SLR) assessments before and after 8 min of CA and CT stretching using an isokinetic dynamometer. Passive stiffness was calculated during each SLR as the slope of the final 10% of the angle-torque curve...
July 24, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28740756/sonographic-evaluation-of-the-immediate-effects-of-eccentric-heel-drop-exercise-on-achilles-tendon-and-gastrocnemius-muscle-stiffness-using-shear-wave-elastography
#7
Wilson K C Leung, K L Chu, Christopher Lai
BACKGROUND: Mechanical loading is crucial for muscle and tendon tissue remodeling. Eccentric heel drop exercise has been proven to be effective in the management of Achilles tendinopathy, yet its induced change in the mechanical property (i.e., stiffness) of the Achilles tendon (AT), medial and lateral gastrocnemius muscles (MG and LG) was unknown. Given that shear wave elastography has emerged as a powerful tool in assessing soft tissue stiffness with promising intra- and inter-operator reliability, the objective of this study was hence to characterize the stiffness of the AT, MG and LG in response to an acute bout of eccentric heel drop exercise...
2017: PeerJ
https://www.readbyqxmd.com/read/28728959/mechanisms-contributing-to-gait-speed-and-metabolic-cost-in-children-with-unilateral-cerebral-palsy
#8
Tatiana Pessoa Silva Pinto, Sérgio Teixeira Fonseca, Rejane Vale Gonçalves, Thales Rezende Souza, Daniela Virgínia Vaz, Paula Lanna Pereira Silva, Marisa Cotta Mancini
BACKGROUND: Gait speed and metabolic cost are indicators of functional capacity in children with cerebral palsy. Uncovering their mechanisms helps guide therapeutic actions. OBJECTIVES: To investigate the contributions of energy-generating and energy-conserving mechanisms to gait speed and metabolic cost of children with unilateral cerebral palsy. METHODS: Data on eccentric and concentric muscle work, co-contraction, elastic torque and vertical stiffness of the affected-limb, forcing torque of the non-affected limb, gait speed and metabolic cost were collected from 14 children with unilateral cerebral palsy, aged 6-12 years...
July 5, 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28723822/biomechanical-differences-in-female-basketball-and-soccer-players-during-multi-directional-jump-landings
#9
Jeffrey B Taylor, Kevin R Ford, Randy J Schmitz, Scott E Ross, Terry A Ackerman, Sandra J Shultz
Anterior cruciate ligament injury prevention programs are less successful in basketball than soccer and may be due to distinct movement strategies that these athletes develop from sport-specific training. The purpose of this study was to identify biomechanical differences between female basketball and soccer players during multi-directional jump landings. Lower extremity biomechanics of eighty-nine female athletes who played competitive basketball (n=40) or soccer (n=49) at the middle- or high-school level were analyzed with three-dimensional motion analysis during a drop vertical jump (DVJ), double- (SAG-DL) and single-leg forward jump (SAG-SL), and double- (FRONT-DL) and single-leg (FRONT-SL) lateral jump...
July 14, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28715304/influence-of-stretching-velocity-on-musculotendinous-stiffness-of-the-hamstrings-during-passive-straight-leg-raise-assessments
#10
Ty B Palmer, Nathaniel D M Jenkins, Brennan J Thompson, Joel T Cramer
BACKGROUND: Recently, passive musculotendinous stiffness (MTS) has been assessed manually in the field; however, when conducting these types of assessments, the stretching velocity must be controlled to avoid eliciting the stretch reflex, which can be observed by increased electromyographic (EMG) amplitude of the stretched muscles and greater resistive torque (indicating the assessment is no longer passive). OBJECTIVE: To examine the effects of slow, medium, and fast stretching velocities during manually-applied passive straight-leg raise (SLR) assessments on hamstrings MTS and EMG amplitude characteristics...
August 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/28709154/contributions-to-leg-stiffness-in-high-compared-with-low-arched-athletes
#11
Douglas W Powell, Max R Paquette, D S Blaise Williams
PURPOSE: High-arched (HA) athletes exhibit greater lower extremity stiffness during functional tasks than low-arched (LA) athletes. The contributions of skeletal and muscular structures to stiffness may underlie the distinct injury patterns observed in these athletes. The purpose of this study was to compare skeletal and muscular contributions to leg stiffness in HA and LA athletes during running and landing tasks. METHODS: Ten HA and 10 LA female athletes performed five overground running trials at a self-selected pace and five step off bilateral landing trials from a height of 30 cm...
August 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28704303/gain-of-length-loss-of-strength-alteration-in-muscle-strength-after-femoral-leg-lengthening-in-young-patients-a-prospective-longitudinal-observational-study
#12
Andreas H Krieg, Sebastian Gehmert, Olivia L Neeser, Xaver Kaelin, Bernhard M Speth
This study aimed to determine the alteration in maximum isokinetic torque in patients after intramedullary femoral leg lengthening. Thirty patients with a median leg-length discrepancy of 3.0 cm underwent femoral limb lengthening with an intramedullary motorized device. Maximum isokinetic, concentric torque of the extensors, and flexors of the knee was measured before (n=30) and 2 years after surgery (n=21). Postoperatively, a significant difference remained for the maximum isokinetic torque of the extensors (22%) between the lengthened and the normal leg, which might have been caused by muscle response to the distraction procedure itself in the form of higher stiffness, less immediate displacement, and inconsistent force relaxation properties...
July 12, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28689459/biomechanical-comparison-of-supraacetabular-external-fixation-and-anterior-pelvic-bridge-plating
#13
Ali Turgay Çavuşoğlu, Fatma Kübra Erbay, Mehmet Hakan Özsoy, Teyfik Demir
Unstable pelvic ring injuries are complex and risky injuries due to high morbidity and mortality. Although anterior pelvic external fixator is a suitable method for rapid stabilization of an injured pelvic ring, due to some disadvantages such as high complication rate, nerve damage, and difficulties of patient's mobility and comfort, there has recently been increased searching for alternative methods for stabilization of the pelvic ring. Pubic symphysis zone freely moves in pelvic models. This study aims to evaluate the biomechanical stability of anterior pelvic bridge plating and compare it with supraacetabular external fixators in an untreated unstable pelvic fracture model...
July 1, 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28686853/wdr26-haploinsufficiency-causes-a-recognizable-syndrome-of-intellectual-disability-seizures-abnormal-gait-and-distinctive-facial-features
#14
Cara M Skraban, Constance F Wells, Preetha Markose, Megan T Cho, Addie I Nesbitt, P Y Billie Au, Amber Begtrup, John A Bernat, Lynne M Bird, Kajia Cao, Arjan P M de Brouwer, Elizabeth H Denenberg, Ganka Douglas, Kristin M Gibson, Katheryn Grand, Alice Goldenberg, A Micheil Innes, Jane Juusola, Marlies Kempers, Esther Kinning, David M Markie, Martina M Owens, Katelyn Payne, Richard Person, Rolph Pfundt, Amber Stocco, Claire L S Turner, Nienke E Verbeek, Laurence E Walsh, Taylor C Warner, Patricia G Wheeler, Dagmar Wieczorek, Alisha B Wilkens, Evelien Zonneveld-Huijssoon, Tjitske Kleefstra, Stephen P Robertson, Avni Santani, Koen L I van Gassen, Matthew A Deardorff
We report 15 individuals with de novo pathogenic variants in WDR26. Eleven of the individuals carry loss-of-function mutations, and four harbor missense substitutions. These 15 individuals comprise ten females and five males, and all have intellectual disability with delayed speech, a history of febrile and/or non-febrile seizures, and a wide-based, spastic, and/or stiff-legged gait. These subjects share a set of common facial features that include a prominent maxilla and upper lip that readily reveal the upper gingiva, widely spaced teeth, and a broad nasal tip...
July 6, 2017: American Journal of Human Genetics
https://www.readbyqxmd.com/read/28668735/characteristics-of-patients-with-fibromyalgia
#15
José Manuel Padín Galea, María Jesús Fernández-Aceñero, José Luis Moreno de la Fuente
BACKGROUND: Fibromyalgia is characterised by generalized pain. A search of the available literature found no previous reports describing the specific characteristics of patients with fibromyalgia. OBJECTIVES: To describe characteristics of patients with fibromyalgia. MATERIAL AND METHODS: Case-control study including 50 patients with fibromyalgia and 50 gender and age-matched controls. After obtaining written informed consent for the study, demographic data were collected and pain in the leg, ankle and foot area was measured using a visual analogue scale (VAS)...
April 4, 2017: Foot
https://www.readbyqxmd.com/read/28659414/how-do-prosthetic-stiffness-height-and-running-speed-affect-the-biomechanics-of-athletes-with-bilateral-transtibial-amputations
#16
Owen N Beck, Paolo Taboga, Alena M Grabowski
Limited available information describes how running-specific prostheses and running speed affect the biomechanics of athletes with bilateral transtibial amputations. Accordingly, we quantified the effects of prosthetic stiffness, height and speed on the biomechanics of five athletes with bilateral transtibial amputations during treadmill running. Each athlete performed a set of running trials with 15 different prosthetic model, stiffness and height combinations. Each set of trials began with the athlete running on a force-measuring treadmill at 3 m s(-1), subsequent trials incremented by 1 m s(-1) until they achieved their fastest attainable speed...
June 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28654438/differences-in-athletic-performance-between-sportsmen-with-symptomatic-femoroacetabular-impingement-and-healthy-controls
#17
Karen Mullins, Michael Hanlon, Patrick Carton
OBJECTIVE: Femoroacetabular impingement (FAI) is a commonly recognized condition in athletes characterized by activity-related hip pain and stiffness, which if left untreated can progress to hip osteoarthritis. The aim of the study was to determine the effect of symptomatic FAI on performance in young athletes based on the hypothesis that athletes with FAI would show deficits in performance compared with healthy controls. DESIGN: The functional performance of a cohort of preoperative, competitive sportsmen with symptomatic FAI (FAI group, n = 54), was compared with that of a group of age, sex and activity-level matched controls (n = 66)...
June 22, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28639442/weightbearing-ankle-dorsiflexion-range-of-motion-and-sagittal-plane-kinematics-during-single-leg-drop-jump-landing-in-healthy-male-athletes
#18
Brittany Dowling, April L McPherson, James M Paci
BACKGROUND: Passive ankle dorsiflexion range of motion (DROM) measures have been identified as a risk factor for injury during landings. However, passive measurements might not be indicative of dynamic ankle movement, whereas a weightbearing ROM might be a better tool when evaluating movement. The purpose of this study was to investigate the relationship between weightbearing DROM and sagittal plane landing mechanics in a single leg drop jump task. METHODS: 73 male athletes (22...
June 21, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28630737/mesenchymal-stem-cell-therapy-in-the-treatment-of-hip-osteoarthritis
#19
Rodrigo Mardones, Claudio M Jofré, L Tobar, José J Minguell
This study was performed to investigate the safety and efficacy of the intra-articular infusion of ex vivo expanded autologous bone marrow-derived mesenchymal stem cells (BM-MSC) to a cohort of patients with articular cartilage defects in the hip. The above rationale is sustained by the notion that MSCs express a chondrocyte differential potential and produce extracellular matrix molecules as well as regulatory signals, that may well contribute to cure the function of the damaged hip joint. A cohort of 10 patients with functional and radiological evidences of hip osteoarthritis, either in one or both legs, was included in the study...
July 2017: Journal of Hip Preservation Surgery
https://www.readbyqxmd.com/read/28628370/multiple-joint-exercises-using-elastic-resistance-bands-vs-conventional-resistance-training-equipment-a-cross-over-study
#20
Vegard M Iversen, Paul Jarle Mork, Ottar Vasseljen, Ronny Bergquist, Marius S Fimland
Previous studies indicate that elastic resistance bands (ERB) can be a viable option to conventional resistance-training equipment (CRE) during single-joint resistance exercises, but their efficacy has not been established for several commonly used multiple-joint resistance exercises. Thus, we compared muscular activation levels in four popular multiple-joint exercises performed with ERB (TheraBand(®)) vs. CRE (Olympic barbell or cable pulley machines). In a cross-over design, men and women (n = 29) performed squats, stiff-legged deadlifts, unilateral rows and lateral pulldown using both modalities...
September 2017: European Journal of Sport Science
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