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https://www.readbyqxmd.com/read/28440017/a-study-of-the-vasera-arterial-stiffness-device-in-us-patients
#1
George Maliha, Raymond R Townsend
The cardio-ankle vascular index (CAVI) represents a promising index of arterial stiffness. However, neither the CAVI measure nor its measurement device, the VaSera, have undergone general testing in a North American clinical setting. To begin the process of collecting normal values in the United States, we studied 20 male and 28 female volunteers without reported cardiovascular or renal disease and no history of smoking. Their CAVIs, ankle-brachial indices (ABIs), and four-limb blood pressures were measured in three positions: supine, 7° Trendelenburg, and 7° reverse Trendelenburg...
April 25, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28436534/a-novel-trpa1-variant-is-associated-with-carbamazepine-responsive-cramp-fasciculation-syndrome
#2
M J Nirenberg, R Chaouni, T M Biller, R M Gilbert, C Paisán-Ruiz
Cramp-fasciculation syndrome (CFS) is a rare muscle hyperexcitability syndrome that presents with muscle cramps, fasciculations, and stiffness, as well as pain, fatigue, anxiety, hyperreflexia, and paresthesias. Although familial cases have been reported, a genetic etiology has not yet been identified. We performed whole-exome sequencing followed by validation and cosegregation analyses on a father-son pair with CFS. Both subjects manifested other hypersensitivity-hyperexcitability symptoms, including asthma, gastroesophageal reflux, migraine, restless legs syndrome, tremor, cold hyperalgesia, and cardiac conduction defects...
April 24, 2017: Clinical Genetics
https://www.readbyqxmd.com/read/28428826/the-reliability-of-shear-elastic-modulus-measurement-of-the-ankle-plantar-flexion-muscles-is-higher-at-dorsiflexed-position-of-the-ankle
#3
Junya Saeki, Tome Ikezoe, Masatoshi Nakamura, Satoru Nishishita, Noriaki Ichihashi
BACKGROUND: Excessive stiffness of lower limb muscles is associated with sports injuries. Therefore, the identification of a reliable measurement of the shear elastic modulus of various ankle plantar flexion muscles is required to evaluate lower leg sports injuries. This study investigated the reliable measurement of the shear elastic modulus of the ankle plantar flexion muscles at different ankle positions. METHODS: Twenty-three healthy young men (25.3 ± 3...
2017: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/28422623/knee-stiffness-and-viscosity-new-implementation-and-perspectives-in-prosthesis-development
#4
Klemen Bohinc, Nejc Vantur, Drago Torkar, Tomaž Lampe, Marija Hribernik, Miroljub Jakovljević
The pendulum test is a method applied to measure passive resistance of the knee. A new and simple pendulum test with instrumentation based on infrared camera was used to evaluate knee stiffness and viscosity on a female human cadaver. The stiffness and viscosity were calculated based on the kinetic data. During the measurements, the periarticular and intraarticular soft tissue of the knee was gradually removed to determine the stiffness and viscosity as a function of the tissue removal rate. The measurements showed that the removal of tissue around the joint reduces the damping of leg oscillation, and therefore decreases the stiffness and viscosity...
April 19, 2017: Bosnian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28412025/the-influence-of-chronic-il-6-exposure-in-vivo-on-rat-achilles-tendon-extracellular-matrix
#5
Mark S Katsma, Shivam H Patel, Erica Eldon, Kathryn A Corbell, Kevin L Shimkus, James D Fluckey, Chad C Carroll
When compared to placebo, acetaminophen (APAP) reduces tendon stiffness and collagen cross-linking. APAP also enhances the exercise-induced increase in peritendinous levels of IL-6. Elevated levels of IL-6 are associated with tendinopathy, thus we hypothesized that chronic, elevated peritendinous IL-6 would alter tendon extracellular matrix (ECM). IL-6 (∼3000pgml(-1)) was injected (3dwk(-1) for 8-wks) into the Achilles peritendinous region of male Wistar rats (n=16) with the opposite leg serving as a sham...
April 13, 2017: Cytokine
https://www.readbyqxmd.com/read/28397006/acute-effect-of-stretching-one-leg-on-regional-arterial-stiffness-in-young-men
#6
Yosuke Yamato, Natsuki Hasegawa, Shumpei Fujie, Shigehiko Ogoh, Motoyuki Iemitsu
PURPOSE: Our previous study demonstrated that a single bout of stretching exercises acutely reduced arterial stiffness. We hypothesized that this acute vascular response is due to regional mechanical stimulation of the peripheral arteries. To test this hypothesis, we examined the effect of a single bout of passive one leg stretching on arterial stiffness, comparing the stretched and the non-stretched leg in the same subject. METHODS: Twenty-five healthy young men (20...
April 10, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28391391/the-acute-benefits-and-risks-of-passive-stretching-to-the-point-of-pain
#7
Pornpimol Muanjai, David A Jones, Mantas Mickevicius, Danguole Satkunskiene, Audrius Snieckus, Albertas Skurvydas, Sigitas Kamandulis
PURPOSE: This study evaluated the acute effects of two different stretch intensities on muscle damage and extensibility. METHODS: Twenty-two physically active women (age 20 ± 1.0 years) were divided into two matched groups and undertook eight sets of 30-s passive hamstring stretching. One group stretched to the point of discomfort (POD) and the other to the point of pain (POP). Hamstring passive torque, sit and reach (S&R), straight leg raise (SLR), and markers of muscle damage were measured before, immediately after stretching and 24 h later...
April 8, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28389837/use-of-internal-lengthening-nails-in-post-traumatic-sequelae
#8
REVIEW
Hamza M Alrabai, Martin G Gesheff, Janet D Conway
External fixators are a well-established modality for treating fractures with bone defects, leg-length discrepancy, malunion, nonunion and other post-traumatic consequences. However, use of internal lengthening rods has remarkably increased recently for post-traumatic conditions. The main advantage of internal lengthening rods is eliminating pin-site complications. Internal lengthening rods are also associated with less pain. Motorised internal lengthening rods show promising performance in post-traumatic cases...
April 7, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28371740/the-high-cost-of-swing-leg-circumduction-during-human-walking
#9
K Alex Shorter, Amy Wu, Arthur D Kuo
Humans tend to walk economically, with preferred step width and length corresponding to an energetic optimum. In the case of step width, it is costlier to walk with either wider or narrower steps than normally preferred. Wider steps require more mechanical work to redirect the body's motion laterally with each step, but the cost for narrower steps remains unexplained. Here we show that narrow steps are costly because they require the swing leg to be circumducted around the stance leg. Healthy adults (N=8) were tested walking with varying levels of circumduction, induced through lightweight, physical obstructions ("Fins") attached medially to the lower legs, during treadmill walking at fixed speed (1...
March 23, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28368956/the-effect-of-varying-plyometric-volume-on-stretch-shortening-cycle-capability-in-collegiate-male-rugby-players
#10
Mark Jeffreys, Mark De Ste Croix, Rhodri S Lloyd, Jon L Oliver, Jonathan Hughes
The purpose of this study was to identify the effectiveness of low and high volume plyometric loads on developing stretch shortening cycle capability in collegiate rugby players. A between- group repeated measures design was used. Thirty six subjects (age 20.3 ±1.6 yrs, mass 91.63 ±10.36kg, stature 182.03 ±5.24cm) were randomly assigned to one of three groups, a control group (CG), a low volume plyometric group (LPG) or a high volume plyometric group (HPG). Data were collected from a force plate, and measures of reactive strength index (RSI) and leg stiffness were calculated from jump height, contact time and flight time...
March 25, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28360121/prosthetic-model-but-not-stiffness-or-height-affects-the-metabolic-cost-of-running-for-athletes-with-unilateral-transtibial-amputations
#11
Owen N Beck, Paolo Taboga, Alena Marie Grabowski
Running-specific prostheses enable athletes with lower limb amputations to run by emulating the spring-like function of biological legs. Current prosthetic stiffness and height recommendations aim to mitigate kinematic asymmetries for athletes with unilateral transtibial amputations. However, it's unclear how different prosthetic configurations influence the biomechanics and metabolic costs of running. Consequently, we investigated how prosthetic model, stiffness, and height affect the biomechanics and metabolic costs of running...
March 30, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28356622/evaluation-of-the-relationship-between-the-static-measurement-of-transverse-arch-flexibility-of-the-forefoot-and-gait-parameters-in-healthy-subjects
#12
Takashi Kondo, Takeshi Muneta, Tsutomu Fukui
[Purpose] To investigate the relationship between the static measurement of the transverse arch of the forefoot, using a 3-dimensional (3D) foot scanner, and kinetics and kinematics of gait parameters in the sagittal plane. [Subjects and Methods] Twenty healthy subjects participated in this study. The transverse arch of the forefoot was measured under three conditions as follows: condition 1, sitting; condition 2, standing; and condition 3, foot forward and lower leg tilting anteriorly to the maximum position with heel contact...
March 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28353683/model-based-estimation-of-ankle-joint-stiffness
#13
Berno J E Misgeld, Tony Zhang, Markus J Lüken, Steffen Leonhardt
We address the estimation of biomechanical parameters with wearable measurement technologies. In particular, we focus on the estimation of sagittal plane ankle joint stiffness in dorsiflexion/plantar flexion. For this estimation, a novel nonlinear biomechanical model of the lower leg was formulated that is driven by electromyographic signals. The model incorporates a two-dimensional kinematic description in the sagittal plane for the calculation of muscle lever arms and torques. To reduce estimation errors due to model uncertainties, a filtering algorithm is necessary that employs segmental orientation sensor measurements...
March 29, 2017: Sensors
https://www.readbyqxmd.com/read/28353085/alterations-in-mechanical-properties-of-the-patellar-tendon-is-associated-with-pain-in-athletes-with-patellar-tendinopathy
#14
W C Lee, Z J Zhang, L Masci, G Y F Ng, Siu Ngor Fu
PURPOSE: To compare tendon strain and stiffness between athletes with patellar tendinopathy and healthy controls, and explore whether the intensity of pain and dysfunction were related to the mechanical properties of the tendon. METHODS: Thirty-four male athletes with patellar tendinopathy and 13 healthy controls matched by age and activity levels were recruited. The in vivo mechanical properties of the patellar tendon were examined by ultrasonography and dynamometry...
March 28, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28318604/comparison-of-whole-body-vertical-stiffness-and-leg-stiffness-during-single-leg-hopping-in-place-in-children-and-adults
#15
Matthew Beerse, Jianhua Wu
In the hopping literature, whole-body vertical stiffness and leg stiffness are used interchangeably, due to most of the movement occurring in the vertical direction. However, there is some anterior/posterior movement of the center of mass and displacements of the foot during hopping in place in both children and adults. Further it is not understood if leg stiffness show a similar pattern as whole-body vertical stiffness when increasing hopping frequency. The purpose of this study was to test if whole-body vertical stiffness and leg stiffness are different during single-leg hopping in-place in children and adults, across a range of frequencies...
March 9, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28299388/the-combination-of-tibial-anterior-translation-and-axial-rotation-into-a-single-biomechanical-factor-improves-the-prediction-of-patient-satisfaction-over-each-factor-alone-in-patients-with-acl-reconstructed-knees
#16
Thomas P Branch, Shaun K Stinton, William C Hutton, Philippe Neyret
PURPOSE: The purpose of this study was to identify biomechanical factors, in both reconstructed and healthy knees, that correlate with patient satisfaction after ACL reconstruction. METHODS: Seventeen patients who had undergone unilateral ACL reconstruction were reviewed 9 years post-op. Patients completed subjective questionnaires and underwent manual knee laxity testing (Lachman-Trillat, KT-1000, and pivot shift) and automated laxity testing. During automated testing, both legs were rotated into external rotation and then internal rotation until peak rotational torque reached 5...
March 15, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28296926/relationship-between-decreased-lower-extremity-muscle-mass-and-knee-pain-severity-in-both-the-general-population-and-patients-with-knee-osteoarthritis-findings-from-the-knhanes-v-1-2
#17
Yun-Hong Cheon, Hyun-Ok Kim, Young Sun Suh, Min Gyo Kim, Wan-Hee Yoo, Rock Bum Kim, Hyun-Su Yang, Sang-Il Lee, Ki-Soo Park
OBJECTIVE: To identify the prevalence of and risk factors for knee pain and radiographic knee osteoarthritis (RKOA) and to investigate the relationship between decreased lower extremity muscle mass (DLEM) and knee pain severity. METHODS: Using data from the Korea National Health and Nutrition Examination Survey, 3,278 participants who were ≥50 years old and who underwent dual x-ray absorptiometry, plain knee radiographs and completed a knee pain questionnaire were enrolled...
2017: PloS One
https://www.readbyqxmd.com/read/28290718/assessments-of-mechanical-stiffness-and-relationships-to-performance-determinants-in-middle-distance-runners
#18
Simon A Rogers, Chris S Whatman, Simon N Pearson, Andrew E Kilding
PURPOSE: This study aimed to examine relationships between methods of lower-limb stiffness and their associations with running economy (RE) and maximal velocity (vmax) in middle-distance (MD) runners. METHODS: Eleven highly-trained male MD runners performed a series of mechanical and physiological tests to determine maximal overground sprint speed, RE and V̇O2peak. Achilles tendon stiffness (kT) was estimated using ultrasonography during maximal isometric ankle plantarflexion...
March 14, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28269317/sudden-changes-in-walking-surface-compliance-evoke-contralateral-emg-in-a-hemiparetic-walker-a-case-study-of-inter-leg-coordination-after-neurological-injury
#19
Jeffrey Skidmore, Panagiotis Artemiadis
Gait impairment due to neurological disorders is a significant problem around the world. Despite the growing interest in using robotic devices for gait rehabilitation, their widespread use remains limited as there is no clear evidence that robot-assisted gait therapy is superior to traditional treadmill-based therapy. This work is a case study that focuses on investigating the existence of mechanisms of inter-leg coordination after neurological injury, and based on that, proposing novel methods for gait rehabilitation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268771/knee-orthosis-with-variable-stiffness-and-damping-that-simulates-hemiparetic-gait
#20
Christina-Anne Lahiff, Tyagi Ramakrishnan, Seok Hun Kim, Kyle Reed
Individuals with unilateral stroke have neuromuscular weakness or paralysis on one side of the body caused by some muscles disengaging and others overexciting. Hyperextension of the knee joint and complete lack of plantar flexion of the ankle joint are common symptoms of stroke. This paper focuses on the creation and implementation of a small, lightweight, and adjustable orthotic device to be positioned around the knee of an able-bodied person to simulate hemiparetic gait. Force and range of motion data from able-bodied subjects fitted with the orthosis, inducing hemiparetic gait, was collected using the Computer Assisted Rehabilitation ENvironment (CAREN) system...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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