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https://www.readbyqxmd.com/read/28225488/association-between-beat-to-beat-blood-pressure-variability-and-vascular-elasticity-in-normal-young-adults-during-the-cold-pressor-test
#1
Yufa Xia, Dan Wu, Zhifan Gao, Xin Liu, Qian Chen, Lijie Ren, Wanqing Wu
The beat-to-beat blood pressure (BP) monitoring parameters, such as average beat-to-beat BP, BP variability (BPV), could have an influence on the vascular elasticity. This study hypothesized that the elevated beat-to-beat BPV could evoke the reduction of the vascular elasticity independent of BP levels. We measured the beat-to-beat BP recordings and total arterial compliance (TAC), which was used to assess the vascular elasticity, in 80 young healthy adults during the cold pressor test (CPT). The CPT included 3 phases: baseline phase, cold stimulus phase, recovery phase...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28223469/maternal-gestational-hypertension-induced-sensitization-of-angiotensin-ii-hypertension-is-reversed-by-renal-denervation-or-angiotensin-converting-enzyme-inhibition-in-rat-offspring
#2
Baojian Xue, Haifeng Yin, Fang Guo, Terry G Beltz, Robert L Thunhorst, Alan Kim Johnson
Numerous findings demonstrate that there is a strong association between maternal health during pregnancy and cardiovascular disease in adult offspring. The purpose of the present study was to test whether maternal gestational hypertension modulates brain renin-angiotensin-aldosterone system (RAAS) and proinflammatory cytokines that sensitizes angiotensin II-elicited hypertensive response in adult offspring. In addition, the role of renal nerves and the RAAS in the sensitization process was investigated. Reverse transcription polymerase chain reaction analyses of structures of the lamina terminalis and paraventricular nucleus indicated upregulation of mRNA expression of several RAAS components and proinflammatory cytokines in 10-week-old male offspring of hypertensive dams...
February 21, 2017: Hypertension
https://www.readbyqxmd.com/read/28222830/impact-of-early-vasopressor-administration-on-neurological-outcomes-after-prolonged-out-of-hospital-cardiac-arrest
#3
Michael W Hubble, Clark Tyson
: Introduction Vasopressors are associated with return of spontaneous circulation (ROSC), but no long-term benefit has been demonstrated in randomized trials. However, these trials did not control for the timing of vasopressor administration which may influence outcomes. Consequently, the objective of this study was to develop a model describing the likelihood of favorable neurological outcome (cerebral performance category [CPC] 1 or 2) as a function of the public safety answering point call receipt (PSAP)-to-pressor-interval (PPI) in prolonged out-of-hospital cardiac arrest...
February 22, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28219980/activation-of-neuronal-endothelin-b-receptors-mediates-pressor-response-through-alpha-1-adrenergic-receptors
#4
Bryan K Becker, Joshua S Speed, Mackenzie Powell, David M Pollock
Abnormalities in activity of the endothelin (ET) system have been widely reported in a number of cardiovascular disease states such as hypertension and heart failure. Although the vascular responses to ET are well established, the interaction between ET and other important modulators of blood pressure, such as the sympathetic nervous system, are less understood. Previous reports implicate ET signaling through ET type B (ETB) receptors in increasing neuronal activity. Therefore, we hypothesized that activation of ETB receptors on sympathetic nerves would increase blood pressure through an adrenergic-mediated mechanism...
February 2017: Physiological Reports
https://www.readbyqxmd.com/read/28207868/acetylcholine-versus-cold-pressor-testing-for-evaluation-of-coronary-endothelial-function
#5
Ahmed AlBadri, Janet Wei, Puja K Mehta, Sofy Landes, John W Petersen, R David Anderson, Bruce Samuels, Babak Azarbal, Eileen M Handberg, Quanlin Li, Margo Minissian, Chrisandra Shufelt, Carl J Pepine, C Noel Bairey Merz
BACKGROUND: Assessment of coronary endothelial function with intracoronary acetylcholine (IC-Ach) provides diagnostic and prognostic data in patients with suspected coronary microvascular dysfunction (CMD), but is often not feasible due in part to the time and expertise needed for pharmacologic mixing. Cold pressor testing (CPT) is a simple and safe stimulus useful for either invasive or non-invasive endothelial function testing and myocardial perfusion imaging but has not been specifically evaluated among symptomatic women with signs of ischemic heart disease (IHD) who have no obstructive coronary artery disease (CAD)...
2017: PloS One
https://www.readbyqxmd.com/read/28190958/the-development-and-psychometric-validation-of-an-arabic-language-version-of-the-pain-catastrophizing-scale
#6
Huda Abu-Saad Huijer, Souha Fares, Douglas J French
Context. The Pain Catastrophizing Scale (PCS) is the most widely used measure of pain-specific catastrophizing. Objectives. The purpose of the present study was to develop and psychometrically evaluate an Arabic-language version of the PCS. Methods. In Study 1, 150 adult chronic nonmalignant pain patients seeking treatment at a hospital setting completed the PCS-A and a number of self-report measures assessing clinical parameters of pain, symptoms of depression, and quality of life. Study 2 employed a cold pressor pain task to examine the PCS-A in a sample of 44 healthy university students...
2017: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/28183818/normalization-of-hemoglobin-based-oxygen-carrier-201-induced-vasoconstriction-roles-of-nitric-oxide-scavenging-and-endothelin
#7
Yannick J Taverne, Daphne P M de Wijs-Meijler, Maaike Te Lintel Hekkert, Paula F Moon-Massat, Greg P Dubé, Dirk Jan Duncker, Daphne Merkus
BACKGROUND: Hemoglobin-based oxygen carrier (HBOC)-201 is a cell-free modified hemoglobin solution potentially facilitating oxygen uptake and delivery in cardiovascular disorders and hemorrhagic shock. Clinical use has been hampered by vasoconstriction in the systemic and pulmonary beds. Therefore we aimed to 1) determine the possibility of counteracting HBOC-201-induced pressor effects with adenosine (ADO), 2) assess the potential roles of nitric oxide (NO) scavenging, reactive oxygen species (ROS) and endothelin (ET) in mediating the observed vasoconstriction and 3) compare these effects in resting and exercising swine...
February 9, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28179624/analysis-of-beat-to-beat-blood-pressure-variability-response-to-the-cold-pressor-test-in-the-offspring-of-hypertensive-and-normotensive-parents
#8
Dan Wu, Lin Xu, Derek Abbott, William Kongto Hau, Lijie Ren, Heye Zhang, Kelvin K L Wong
Abnormal autonomic nervous regulation has an important role in the development of hypertension. As to whether blood pressure (BP) or BP variability represents the proper characteristics for predisposition to hypertension in Chinese young adults remains controversial. We studied the properties of the indices extracted from beat-to-beat BP during a 13 min cold pressor test (CPT). In this study, 69 Chinese young adults including 34 offspring of hypertensive parents (OHPs; 25.6±2.5 years) and 35 offspring of normotensive parents (ONPs; 25...
February 9, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28174437/the-effects-of-a-pelvic-belt-on-trunk-and-lower-extremity-muscles-in-the-bridge-position
#9
Hyun-Gyu Cha, Yan-Ting Wu, Myoung-Kwon Kim
[Purpose] The purpose of this study was to investigate the effects of a pelvic belt on the activities of trunk and lower extremity muscles in normal adults. [Subjects and Methods] The subjects were 20 normal individuals without a history of orthopedic problems. The pelvic compression belt (The Com-Pressor, OPTP, Minneapolis, MN, USA) was an adjustable body belt with four elastic compression bands that provide stabilizing pressure and was designed to adjust the amount of force applied and to alter sites of compression...
December 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28168774/when-i-get-like-that-put-a-gun-to-my-head
#10
Nancy Lutwak, Curt Dill
Yesterday a 95 year old man with prostate carcinoma and widespread bone metastases was brought to the emergency department because of blood in his urine after he pulled on his foley. At triage he was febrile and hypotensive, moaning incoherently which was not a change in mental status. Despite IV fluid hydration and pressors his blood pressure remained low. This article is protected by copyright. All rights reserved.
February 7, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28162323/-519-the-effect-of-prior-experience-with-cold-pain-on-pain-tolerance-in-the-cold-pressor-task-the-mediating-effect-of-situational-catastrophizing
#11
R Gibler, E Beckmann, C King, K Jastrowski Mano
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28161474/the-impact-of-parental-modeling-on-child-pain-responses-the-role-of-parent-and-child-sex
#12
Katelynn E Boerner, Christine T Chambers, Patrick J McGrath, Vincent LoLordo, Rudolf Uher
: Social modeling is a process by which pain behaviours are learned, and research has found parents act as models for their children's behaviour. Despite social learning theory predicting that same-sex models have greater impact, no experimental investigation to date has examined the role of sex of the model or observer in social learning of pediatric pain. The present study recruited 168 parent-child dyads (equal father-son, father-daughter, mother-son, and mother-daughter dyads) where children were generally healthy 6- to 8-year-olds...
February 1, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28150139/acute-effects-of-moderate-continuous-training-on-stress-test-related-pulse-pressure-and-wave-reflection-in-healthy-men
#13
Florian Milatz, Sascha Ketelhut, Reinhard G Ketelhut
INTRODUCTION: Arterial dysfunction develops early in life even in individuals with modest cardiovascular risk. Stress is associated with increased risk in cardiovascular morbidity and mortality. AIM: The main objectives of this study were to investigate the acute effects of moderate continuous training (MCT) on established markers of arterial stiffness and cardiovascular risk during standardized cold pressor stress testing (CPT). METHODS: 29 young healthy male subjects (33...
February 2, 2017: High Blood Pressure & Cardiovascular Prevention: the Official Journal of the Italian Society of Hypertension
https://www.readbyqxmd.com/read/28141635/observer-influences-on-pain-an-experimental-series-examining-same-sex-and-opposite-sex-friends-strangers-and-romantic-partners
#14
Rhiannon Edwards, Christopher Eccleston, Edmund Keogh
Despite well documented sex and gender differences, little is known about the relative impact of male-female social interactions on pain. Three experiments were conducted to investigate whether the type of interpersonal relationship men and women have with an observer affects how they respond to experimental pain. Study 1 recruited friends and strangers, Study 2 examined the effects of same and opposite-sex friends, whereas Study 3 investigated the differences between opposite-sex friends and opposite-sex romantic partners...
January 10, 2017: Pain
https://www.readbyqxmd.com/read/28137984/alkaline-phosphatase-inhibitors-attenuate-renovascular-responses-to-norepinephrine
#15
Edwin K Jackson, Yumeng Zhang, Dongmei Cheng
Tissue nonspecific alkaline phosphatase (TNAP) contributes to the production of adenosine by the kidney, and A1-receptor activation enhances renovascular responses to norepinephrine. Therefore, we hypothesized that TNAP regulates renovascular responsiveness to norepinephrine. In isolated, perfused rat kidneys, the TNAP inhibitor l-p-bromotetramisole (0.1 mmol/L) decreased renal venous levels of 5'-AMP (adenosine precursor) and adenosine by 61% (P<0.0384) and 62% (P=0.0013), respectively, at 1 hour into treatment and caused a 10-fold rightward shift of the concentration-response relationship to exogenous norepinephrine (P<0...
March 2017: Hypertension
https://www.readbyqxmd.com/read/28135808/behavioral-assessment-of-the-negative-emotion-aspect-of-distress-tolerance
#16
Jennifer C Veilleux, Garrett A Pollert, Melissa J Zielinski, Jennifer A Shaver, Morgan A Hill
The current behavioral tasks assessing distress tolerance measure tolerance to frustration and tolerance to physical discomfort, but do not explicitly assess tolerance to negative emotion. We closely evaluated the conceptual distinctions between current behavioral tasks and self-report tasks assessing distress tolerance, and then developed a new behavioral distress tolerance task called the Emotional Image Tolerance (EIT) task. The EIT task retains elements of existing behavioral tasks (e.g., indices of persistence) while augmenting the reliability and content sufficiency of existing measures by including multiple trials, including a variety of negative affect stimuli, and separating overall task persistence from task persistence after onset of distress...
January 1, 2017: Assessment
https://www.readbyqxmd.com/read/28129249/correlation-of-carotid-artery-reactivity-with-cardiovascular-risk-factors-and-coronary-artery-vasodilator-responses-in-asymptomatic-healthy-volunteers
#17
Anke C C M van Mil, Yvonne Hartman, Frederieke van Oorschot, Annemieke Heemels, Nikki Bax, Ellen A Dawson, Nicola Hopkins, Maria T E Hopman, Daniel J Green, David L Oxborough, Dick H J Thijssen
OBJECTIVES: Carotid artery reactivity (CAR%), involving carotid artery diameter responses to a cold pressor test (CPT), is a noninvasive measure of conduit artery function in humans. This study examined the impact of age and cardiovascular risk factors on the CAR% and the relationship between CAR% and coronary artery vasodilator responses to the CPT. METHODS: Ultrasound was used to measure resting and peak carotid artery diameters during the CPT, with CAR% being calculated as the relative change from baseline (%)...
January 27, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28124117/pain-and-executive-functions-a-unique-relationship-between-stroop-task-and-experimentally-induced-pain
#18
Jovana Bjekić, Marko Živanović, Danka Purić, Joukje M Oosterman, Saša R Filipović
There is a growing body of evidence that a higher level of cognitive inhibition is associated with lower experimental pain sensitivity. However, a systematic examination of the association between executive functions, which include not only inhibition but also updating and shifting, and experimental pain sensitivity is lacking. This study aimed to overcome this limitation by exploring the relationship between a range of executive functions and different measures of experimentally induced cold pain in healthy participants...
January 25, 2017: Psychological Research
https://www.readbyqxmd.com/read/28096689/influence-of-exercise-on-visceral-pain-an-explorative-study-in-healthy-volunteers
#19
Laura Jgm van Weerdenburg, Christina Brock, Asbjørn Mohr Drewes, Harry van Goor, Marjan de Vries, Oliver Hg Wilder-Smith
BACKGROUND AND OBJECTIVES: Contradictory results have been found about the effect of different exercise modalities on pain. The aim of this study was to investigate the early effects of aerobic and isometric exercise on different types of experimental pain, including visceral pain, compared to an active control condition. METHODS: Fifteen healthy subjects (6 women, mean [standard deviation] age 25 [6.5] years) completed 3 interventions consisting of 20 minutes of aerobic cycling, 12 minutes of isometric knee extension and a deep breathing procedure as active control...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28096436/angiotensin-ii-induces-differential-insulin-action-in-rat-skeletal-muscle
#20
Juthamard Surapongchai, Mujalin Prasannarong, Tepmanas Bupha-Intr, Vitoon Saengsirisuwan
Angiotensin II (ANGII) is reportedly involved in the development of skeletal muscle insulin resistance. The present investigation evaluated the effects of two ANGII doses on the phenotypic characteristics of insulin resistance syndrome and insulin action and signaling in rat skeletal muscle. Male Sprague-Dawley rats were infused with either saline (SHAM) or ANGII at a commonly used pressor dose (100 ng/kg/min; ANGII-100) or a higher pressor dose (500 ng/kg/min; ANGII-500) via osmotic minipumps for 14 days. We demonstrated that ANGII-100-infused rats exhibited the phenotypic features of non-obese insulin resistance syndrome, including hypertension, impaired glucose tolerance and insulin resistance of glucose uptake in the soleus muscle, whereas ANGII-500-treated rats exhibited diabetes-like symptoms, such as post-prandial hyperglycemia, impaired insulin secretion and hypertriglyceridemia...
January 17, 2017: Journal of Endocrinology
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