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Wilma Barcellini, Elisa Scola, Silvia Lanfranconi, Marika Grottaroli, Francesca Binda, Bruno Fattizzo, Anna Zaninoni, Gloria Valcamonica, Claudia Maria Cinnante, Carla Boschetti, Massimiliano Buoli, Carlo Alfredo Altamura, Nereo Bresolin, Fabio Triulzi, Alberto Zanella, Agostino Cortelezzi
This study investigated for the first time brain ischemic involvement in 19 consecutive neurologically asymptomatic PNH patients by non-enhanced cerebral MRI, and by intracranial arterial and venous angio-MRI. Eleven cases (58%, 7 aged <65) showed pathological findings: 9 white matter (WM) abnormalities related to chronic ischemic small vessel disease, 2 a focal abnormality >5 mm, and 5 cases a score >4 by the age-related white matter changes (ARWMC) scale. Compared with age and sex-matched controls (1:2 ratio), patients showed an increased frequency of periventricular WM vascular degeneration (32% versus 5...
January 11, 2018: Scientific Reports
Fengping Liu, Zongxin Ling, Yonghong Xiao, Qing Yang, Li Zheng, Ping Jiang, Lanjuan Li, Wei Wang
Evidence shows that urine has complex bacterial profiles with considerable variation between individuals. Aging and age-related conditions can lead to the changes to the composition of urine, which means that the available nutrition for bacteria in the bladder changes with age. We explored the characteristics of the urinary microbiota of elderly women and whether these are associated with age-related conditions such as diabetes and urinary tract infections. An elderly and a non-elderly cohort of women were included...
November 21, 2017: Oncotarget
Alessandro Delaude, Sabrina Rodriguez-Campos, Anou Dreyfus, Michel Jacques Counotte, Thierry Francey, Ariane Schweighauser, Sophie Lettry, Simone Schuller
Leptospirosis is an important worldwide zoonosis. While human leptospirosis remains rare in Switzerland, the incidence of canine leptospirosis is unusually high compared to other European countries. The aims of this cross-sectional study were to determine the exposure of asymtomatic dogs to pathogenic Leptospira in Switzerland, to characterise risk factors associated with seropositivity and to determine the prevalence of urinary shedding. Sampling was stratified to cover the whole of Switzerland. Sera were tested by microscopic agglutination test for antibodies against a panel of 12 serovars...
June 1, 2017: Preventive Veterinary Medicine
Tim Cundy
No abstract text is available yet for this article.
June 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
Magnus Jonsson, David Lindström, Peter Gillgren, Anders Wanhainen, Jonas Malmstedt
BACKGROUND AND PURPOSE: Long-term outcome after carotid artery stenting (CAS), a less invasive technique than carotid endarterectomy (CEA), for prevention of stroke, is unclear. The aim was to assess long-term outcomes after CAS, compared with CEA, in a nationwide cohort study. METHODS: All patients registered in the national Swedish Vascular Registry (Swedvasc) treated with primary CAS between 2005 and 2012 were identified. For every CAS, 2 CEA controls, matched for sex, age, procedure year, and indication (symtomatic/asymtomatic), were chosen...
August 2016: Stroke; a Journal of Cerebral Circulation
Ulrich Dobrindt, Björn Wullt, Catharina Svanborg
During asymptomatic bacteriuria (ABU), bacteria colonize the urinary tract for extended periods of time without causing symptoms of urinary tract infection. Previous studies indicate that many Escherichia coli (E. coli) strains that cause ABU have evolved from uropathogenic E. coli (UPEC) by reductive evolution and loss of the ability to express functional virulence factors. For instance, the prototype ABU strain 83972 has a smaller genome than UPEC strains with deletions or point mutations in several virulence genes...
2016: Pathogens
G Díaz-Soto, E Romero, J L P Castrillón, O I Jauregui, D de Luis Román
Normocalcemic and asymptomatic hyperparathyroidism diagnosis are becoming more common. However, their pathophysiology is incompletely known. The aim of the present study was to evaluate the clinical effect of calcium-sensing receptor polymorphism (A986S) in normocalcemic and asymtomatic HPT. Prospective study conducted with 61 consecutive normocalcemic and asymptomatic HPT patients was followed up during a minimum period of 1 year. Secondary causes of hyperparathyroidism were ruled out. Calcium and phosphorus metabolism parameters were evaluated in at least 2 determinations during follow-up to classify as normocalcemic or asymptomatic hyperparathyroidism...
March 2016: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
M Llamas-Velasco, N Hilty, W Kempf
BACKGROUND: Porokeratotic adnexal ostial nevus (PAON) is a term that encompass porokeratotic eccrine ostial and dermal duct naevus and porokeratotic eccrine and hair follicle naevus. PAON is a rare adnexal hamartoma characterized by the presence of a cornoid lamella exclusively overlying eccrine acrosyringia or over both, eccrine acrosyringia and hair follicles. OBJECTIVES: Most of the articles on PAON report its clinical or histopathological characteristics but literature review offer scarce data on the evolution or treatment...
October 2015: Journal of the European Academy of Dermatology and Venereology: JEADV
Yeon-Ji Kim, Woo Chul Chung
No abstract text is available yet for this article.
July 2014: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
B Shrestha, R Marhatha, S Kayastha, S Jaishi
Utero-vaginal prolapse is one of the commonest cause for vaginal operations in our country. The expense of this operation can be reduced by reducing duration of catheterization and thereby reducing hospital stay. A prospective, comparative hospital based study was used to assess whether removal of an in-dwelling catheter after 24 hours of vaginal operations with anterior colporrhaphy affects the rate of recatheterization, asymptomatic urinary tract infections, and hospital stay in comparison to 72 hours catheterization...
June 2013: Nepal Medical College Journal: NMCJ
Majid Vafaie, Kaveh Jaseb, Majid Ghanavat, Mohamad Pedram, Tooran Rahiminia
Essential thrombocythemia is a rare myeloproliferative disorder in pediatrics. This myeloproliferative disorder is charactherized by thrombocytosis and hyperplasia of megakaryocytes in the bone marrow. Other cell lines are not involved. JAK2V617F mutation has been identified in approximately half the patients with this disorder. We describe a 12-year-old boy with essential throbocythemia. The patient had a persistent thrombocytosis over 600x10(9) /L and the time of diagnosis, his platelet count ranged between 900x10(9)and 2150x10(9)/L...
2013: International Journal of Hematology-oncology and Stem Cell Research
Xiao-ping Qi, Zhen-guang Chen, Hang-yang Jin, Feng Li, Jun Cheng, Rong-biao Ying, Jian-qiang Zhao, Ding-gang Guo, Shi-yun Luo, Gui-ping Chen, Xian-ning Zhang
OBJECTIVE: To explore the clinical patterns and clinical significance for RET screening in adrenal pheochromocytoma (PHEO) associated with multiple endocrine neoplasia type 2A (MEN2A). METHODS: The clinical data of 32 PHEO patients with MEN2A from 13 unrelated MEN2A pedigrees from August 1989 to January 2013 were analyzed. The comprehensive medical data included systemic examinations and germline RET gene screening. RESULTS: Among 68 patients belonging to 13 MEN2A families, 32 (47...
July 23, 2013: Zhonghua Yi Xue za Zhi [Chinese medical journal]
V Golay, M Trivedi, A Abraham, A Roychowdhary, R Pandey
We report the spectrum of biopsy-proven glomerular disease (GD) in a single center in Eastern India. Medical records of 666 patients with biopsy-proven GD over a period of 2 years from July 2010 to July 2012 were retrospectively analyzed. The clinical, laboratory, and histological data were recorded. All biopsy specimens were examined by the same pathologist with light and immunofluorescence microscopy. Electron microscopic analysis was performed only in selected cases. Histologic spectrum of various GDs was studied along with its correlation with the clinical and laboratory parameters...
May 2013: Indian Journal of Nephrology
Gemma Ortega, Beatriz Álvarez, Manuel Quintana, Marc Ribó, Manuel Matas, José Alvarez-Sabin
Impaired cognitive function is often reported in patients with carotid artery stenosis. Revascularization by transcervical carotid artery stenting (CAS) with flow reversal is associated with increased cognition regardless of age, asymtomatic status, previous stroke events, baseline brain parenchyma status, and contralateral carotid artery stenosis. The findings of this preliminary prospective study suggest that transcervical CAS and stenting with flow reversal for cerebral protection is a safe technique that will improve, or at least not worsen, cognitive performance...
2013: Cerebrovascular Diseases
Anka Mitrasinović, Jovo Kolar, Sandra Radak, Dragoslav Nenezić, Ivana Kupresanin, Nikola Aleksić, Srdjan Babić, Slobodan Tanasković, Dejan Mitrasinović, Djordje Radak
BACKGROUND/AIM: Doppler ultrasonography is now a reliable diagnostic tool for noninvasive examination of the morphology and hemodynamic parameters of extracranial segments of blood vessels that participate in the brain vascularisation. This diagnostic modality in recent years become the only diagnostic tool prior to surgery. The aim of the study was to determine hemodynamic status in symptomatic and asymtomatic patients with severe carotid stenosis prior to and after carotid endarterectomy (CEA)...
May 2012: Vojnosanitetski Pregled. Military-medical and Pharmaceutical Review
Yue-Mei Li, Qiang Liu, Xiang-Yang Li
OBJECTIVE: To observe the therapeutic effect and mechanism of new percutaneous absorption herbal patch for asthma of paracmasis, and to optimize the form of the patch. METHODS: One hundred and twenty cases of paracmasis asthma were randomly divided into medicine patch group, medicinal vesiculation group and western medication group with 40 cases for each. The new percutaneous absorption herbal patch was applied on medicine patch group. Traditional medicinal herbs cake of the hospital were applied on medicinal vesiculation group...
May 2012: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Karthikeyan Ananthasubramaniam, Ritesh Dhar, João L Cavalcante
Chronic heart failure (CHF) is a major and growing problem in the western hemisphere, affecting about 5 million patients in the United States. In daily practice patients with left ventricular systolic dysfunction (LVSD) and significant angiographic coronary artery disease (CAD) are felt to have an ischemic cardiomyopathy (ICMP) and those without CAD or mild-moderate CAD out of proportion to the extent of LVSD are felt to have a non-ischemic cardiomyopathy (NICMP). Although invasive coronary angiography is the gold standard for the diagnosis of CAD, recent advances in non-invasive imaging have created multiple options for evaluating ICMP and NICMP...
July 2011: Heart Failure Reviews
Margrét Brands Viktorsdóttir, Eiriku Jónsson, Hildur Einarsdóttir
We describe a case of right seminal vesicle cyst with ipsilateral renal agenesis in a 25 year old male. The cyst caused severe pain syndrome with progressive perineal pain and pain on defecation and ejaculation. The cyst was surgically removed and the patient became asymtomatic.
October 2010: Læknablađiđ
Necip Ermis, Muhammet Bilgi, Hakan Altay, Tansel Erol
Unicuspid aortic valve is a rare pathology among congenital heart diseases that requires cardiac surgery and is often confused with bicuspid valve. Herein, we report a case of a unicommisural form of unicuspid aortic valve concomitant with aortic aneurysm and secundum type atrial septal defect.
July 2010: Clinical Cardiology
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