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https://www.readbyqxmd.com/read/27774805/-fructose-and-fructose-intolerance
#1
György Miklós Buzás
Although fructose was discovered in 1794, it was realised in recent decades only that its malabsorption can lead to intestinal symptoms while its excessive consumption induces metabolic disturbances. Fructose is a monosaccharide found naturally in most fruits and vegetables. Dietary intake of fructose has gradually increased in the past decades, especially because of the consumption of high fructose corn syrup. With its 16.4 kg/year consumption, Hungary ranks secondly after the United States. Fructose is absorbed in the small intestine by facilitated transport mediated by glucose transporter proteins-2 and -5, and arrives in the liver cells...
October 2016: Orvosi Hetilap
https://www.readbyqxmd.com/read/27752370/barrett-s-oesophagus-in-an-achalasia-patient-immunological-analysis-and-comparison-with-a-group-of-achalasia-patients
#2
Samuel Torres-Landa, Janette Furuzawa-Carballeda, Enrique Coss-Adame, Miguel A Valdovinos, Edgar Alejandro-Medrano, Bárbara Ramos-Ávalos, Braulio Martínez-Benítez, Gonzalo Torres-Villalobos
The aim of the study was to characterize the presence of diverse CD4 and CD8 T cell subsets and regulatory cells in peripheral blood and lower oesophageal sphincter (LES) from a young patient with BE/achalasia without treatment versus achalasia group. In order to characterize the circulating cells in this patient, a cytometric analysis was performed. LES tissue was evaluated by double-immunostaining procedure. Five healthy blood donors, 5 type achalasia patients, and 5 oesophagus tissue samples (gastrooesophageal junction) from transplant donors were included as control groups...
2016: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/27727676/gastrooesophageal-reflux-and-laryngopharyngeal-reflux-and-its-association-with-bronchial-asthma
#3
Pankaj Kumar Singh
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27254026/effects-of-neoadjuvant-chemo-or-chemoradiotherapy-for-oesophageal-cancer-on-perioperative-haemodynamics-a-prospective-cohort-study-within-a-randomised-clinical-trial
#4
Mikael Lund, Jon A Tsai, Magnus Nilsson, Reidar Winter, Lars Lundell, Sigridur Kalman
BACKGROUND: Neoadjuvant chemoradiotherapy might improve oncological outcome compared with chemotherapy after surgery for oesophagus or gastrooesophageal junction cancer. However, radiotherapy may induce cardiovascular side-effects that could increase the risk of perioperative adverse effects and postoperative morbidity. OBJECTIVES: The aim of this study was to compare the perioperative haemodynamics in patients undergoing oesophagectomy following neoadjuvant chemotherapy or chemoradiotherapy for cancer...
September 2016: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/26885979/clinical-impact-of-a-novel-microrna-chemo-sensitivity-predictor-in-gastrooesophageal-cancer
#5
Mette Winther, Steen Knudsen, Jesper Dahlgaard, Thomas Jensen, Anker Hansen, Peter Buhl Jensen, Trine Tramm, Jan Alsner, Marianne Nordsmark
BACKGROUND: miRNAs might be potentially useful biomarkers for prediction of response to chemotherapeutic agents, radiotherapy and survival. The aim of this retrospective study was to validate miRNA response predictors in a cohort of patients with gastrooesophageal cancer in order to predict overall survival (OS) and disease-specific survival (DSS). MATERIAL AND METHODS: The study population encompassed 53 patients treated with curative intend for loco-regional gastrooesophageal cancer...
2016: PloS One
https://www.readbyqxmd.com/read/26835909/morphological-and-functional-assessment-of-oesophageal-mucosa-integrity-in-children-with-cystic-fibrosis
#6
Jernej Brecelj, Nina Zidar, Jera Jeruc, Rok Orel
OBJECTIVES: The aim of the study was to investigate morphological and functional characteristics of oesophageal epithelial barrier in children with cystic fibrosis (CF) with or without gastro-oesophageal reflux disease (GORD) in comparison to healthy controls. METHODS: Oesophagogastroduodenoscopy with oesophageal biopsies and combined oesophageal multichannel intraluminal impedance-pH monitoring was performed in 17 children with CF (CFtot) with (CFgord) or without GORD (CFnorm)...
May 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/26457390/gord-symptoms-in-lung-transplantation-how-efficient-is-the-reflux-symptom-index-questionnaire-compared-to-the-esophageal-impedance-test
#7
COMPARATIVE STUDY
Simona Soresi, Mohamed Zeriouh, Anton Sabashnikov, Grainne Mc Dermott, Alexander Weymann, Jens Wippermann, Thorsten Wahlers, Anna Reed, Martin Carby, Andre R Simon, Aron-Frederik Popov
OBJECTIVE: As Gastroesophageal reflux disease (GORD) affects long-term survival in lung transplant recipients, the aim of this observational prospective study was to analyze the efficacy of The Reflux Symptom Index Questionnaire (RSI) compared to the esophageal impedance test. METHODS: Both esophageal impedance studies and RSI questionnaire were routinely performed in all patients who had completed rehabilitation following lung transplantation from June 2013 till March 2014...
January 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/25743453/mechanisms-of-barrett-s-oesophagus-clinical-los-dysfunction-hiatal-hernia-peristaltic-defects
#8
REVIEW
Sabine Roman, Peter J Kahrilas
Barrett's oesophagus, with the potential to develop into oesophageal adenocarcinoma (OAC), is a major complication of gastrooesophageal reflux disease (GORD). However, about 50% of patients developing OAC had no known GORD beforehand. Hence, while GORD symptoms, oesophagitis, and Barrett's have a number of common determinants (oesophagogastric junction (OGJ) incompetence, impaired oesophageal clearance mechanisms, hiatus hernia) they also have some independent determinants. Further, although excess oesophageal acid exposure plays a major role in the genesis of long-segment Barrett's oesophagus there is minimal evidence supporting this for short-segment Barrett's...
February 2015: Best Practice & Research. Clinical Gastroenterology
https://www.readbyqxmd.com/read/25638618/simple-fundoplication-versus-additional-vagotomy-and-pyloroplasty-in-neurologically-impaired-children-a-single-centre-experience
#9
J Fraser Horwood, William Calvert, Dhanya Mullassery, Mohammed Bader, Matthew O Jones
BACKGROUND AND AIMS: Gastrooesophageal reflux disease (GERD) is a significant problem in children with neurological impairment (NI) with high failure rates for fundoplication. Fundoplication with vagotomy and pyloroplasty (FVP) can improve the outcome by altering the sensory or motor dysfunction associated with the reflux. We report our comparative outcomes for simple fundoplication (SF) and FVP in NI children. METHODS: Case records of all patients having fundoplication under a single consultant at a tertiary UK paediatric surgical centre between January 1997 and December 2012 were retrospectively assessed for recurrent symptoms and redo surgery...
February 2015: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/25614833/laparoscopic-watson-fundoplication-is-effective-and-durable-in-children-with-gastrooesophageal-reflux
#10
Matthew G Dunckley, Kapil M Rajwani, Anies A Mahomed
Gastroesophageal reflux (GOR) affects 2-8% of children over 3 years of age and is associated with significant morbidity. The disorder is particularly critical in neurologically impaired children, who have a high risk of aspiration. Traditionally, the surgical antireflux procedure of choice has been Nissen's operation. However, this technique has a significant incidence of mechanical complications and has a reoperation rate of approximately 7%, leading to the development of alternative approaches. Watson's technique of partial anterior fundoplication has been shown to achieve long-lasting reflux control in adults with few mechanical complications, but there is limited data in the paediatric population...
2014: Minimally Invasive Surgery
https://www.readbyqxmd.com/read/25516655/oesophageal-flap-valvuloplasty-and-wrapping-suturing-prevent-gastrooesophageal-reflux-disease-in-dogs-after-oesophageal-anastomosis
#11
Ji-Gang Dai, Quan-Xing Liu, Xu-Feng Den, Jia-Xin Min
AIM: To examine the efficiency of oesophageal flap valvuloplasty and wrapping suturing technique in decreasing the rate of postoperative gastrooesophageal reflux disease in a dog model. METHODS: We operated on 10 dogs in this study. First, we resected a 5-cm portion of the distal oesophagus and then restored the continuity of the oesophageal and gastric walls by end-to-end anastomosis. A group of five dogs was subjected to the oesophageal flap valvuloplasty and wrapping suturing technique, whereas another group (control) of five dogs was subjected to the stapling technique after oesophagectomy...
December 14, 2014: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/25377517/-the-influence-of-laparoscopic-fundoplication-on-reflux-associated-cough
#12
G Drews, F Rudolph, O Martinenko, P Kühne, J Schreiber
Introduction: The gastrooesophageal reflux disease (GERD) is a possible cause of chronic cough. The laparoscopic fundoplication is well established in the treatment of GERD. In a retrospective study, the effectivity of this operation on the GERD associated cough was examined and possible preoperative predictive factors concerning the post-surgical therapy effect were characterized. Patients and Methods: 85 patients after laparoscopic fundoplication due to GERD treated with proton pump inhibitors without (RS-H: n = 31) or with associated cough (RS+H: n = 54) were evaluated in a three-month follow-up by data analysis regarding an indication point score from typical symptoms as well as findings (gastroscopy, histology, 24-hour oesophagus pH-metry)...
November 6, 2014: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/25207185/factors-affecting-the-prevalence-of-gastro-oesophageal-reflux-in-childhood-corrosive-oesophageal-strictures
#13
Serdar H Iskit, Zerrin Ozçelik, Murat Alkan, Selcan Türker, Unal Zorludemir
BACKGROUND: Gastro-oesophageal reflux may accompany the corrosive oesophageal damage caused by the ingestion of corrosive substances and affect its treatment. The factors that affect the development of reflux in these cases and their effects on treatment still remain unclear. AIMS: Our aim is to investigate the prevalence of gastro-oesophageal reflux in children with corrosive oesophageal strictures, the risk factors affecting this prevalence and the effects of gastro-oesophageal reflux on treatment...
June 2014: Balkan Medical Journal
https://www.readbyqxmd.com/read/25148734/measured-gap-length-and-outcomes-in-oesophageal-atresia
#14
Hemanshoo S Thakkar, Joseph Cooney, Neetu Kumar, Edward Kiely
AIMS: Oesophageal atresia (OA) with or without tracheoesophageal fistula (TOF) is the most common congenital anomaly of the oesophagus. There is limited literature suggesting a linear relationship between increasing gap length and the incidence of all major complications. We sought to assess whether measured gap length at the time of surgery was related to outcomes in our patients. METHODS: All patients with a diagnosis of OA +/- TOF who underwent repair under a single surgeon between 1983 and 2012 were included...
September 2014: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/25097965/-postoperative-reflux-in-treatment-of-complicated-forms-of-duodenal-ulcer-disease
#15
N N Veligotskiĭ, V V Komarchuk, A S Trushin, A V Gorbulich, E V Komarchuk
There were examined 46 patients, in whom operative treatment of perforative duodenal ulcer was conducted. Organ-preserving operations were performed in conjunction with selective proxymal or truncal vagotomy. In far-remote terms after the operation in 12 patients gastrooesophageal reflux have occurred, DeMeester index have constituted 17.5-38.5. Impact of operative trauma on antireflux power of gastro-oesophageal junction was noted.
April 2014: Klinichna Khirurhiia
https://www.readbyqxmd.com/read/24163764/the-postoperative-component-of-magic-chemotherapy-is-associated-with-improved-prognosis-following-surgical-resection-in-gastric-and-gastrooesophageal-junction-adenocarcinomas
#16
A Mirza, S Pritchard, I Welch
AIMS: MAGIC chemotherapy has become the standard of treatment for patients undergoing curative resection for gastric and gastrooesophageal junction (GOJ) cancers. The importance of postoperative component of this regimen is uncertain. The aim of this study was to compare survival and cancer recurrence in patients who have received neoadjuvant and adjuvant chemotherapies according to MAGIC protocol with those patients completing only neoadjuvant chemotherapy. METHODS: 66 patients with gastric and GOJ adenocarcinomas treated with neoadjuvant and adjuvant chemotherapies according to the MAGIC protocol were studied...
2013: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/24140511/-patient-satisfaction-with-care-in-gastrooesophageal-reflux-disease
#17
Nikolett Szarka, Zsolt Nagykáldi, Mária Végh, János Oberling
INTRODUCTION: Besides medical treatment, adequate communication and personal relationships between physicians and patients are the most important determinants of patient satisfaction. AIM: To explore doctor-patient relationships, and factors that may determine patient satisfaction with care. METHOD: Patients with gastroesophageal reflux (n = 80) were divided into subgroups treated by family doctors or by gastroenterologists. Patients were asked to fill in a questionnaire about communication and patient satisfaction...
October 27, 2013: Orvosi Hetilap
https://www.readbyqxmd.com/read/23950075/-laparoscopic-toupet-fundoplication
#18
A Kirschniak, R Pointner, F A Granderath
The laparoscopic fundoplicatio is the "gold standard" among surgical therapy of gastrooesophageal reflux disease. In this context the Toupet fundoplicatio is an alternative indication to the Nissen fundoplicatio. The lesser dysphagia rate is specified as postoperative advantage. To avoid complications, a standardized procedure is relevant for a good postoperative outcome, even in more complex procedures. In this article, the indications and surgical methods are illustrated, as they are performed by the authors...
August 2013: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/23909114/laryngopharyngeal-reflux-and-primary-snoring-a-pilot-case-control-study
#19
N Charaklias, C Mamais, V Pothula, B N Kumar
STUDY OBJECTIVES: Laryngopharyngeal reflux has been implicated as a causative factor in the aetiology of sleep related breathing disorders. However there are no reports on the association of this disorder and primary snoring in the absence of obstructive sleep apnoea. This study was undertaken to investigate any link between primary snoring and the presence of laryngopharyngeal reflux. METHODS: A matched case-control study was performed in a district general Ear Nose Throat outpatient population in the United Kingdom...
2013: B-ENT
https://www.readbyqxmd.com/read/23441441/pattern-of-airway-inflammation-and-remodelling-in-mild-persistent-atopic-asthma-and-in-mild-persistent-asthma-related-to-gastroesophageal-reflux
#20
COMPARATIVE STUDY
R W Dal Negro, M Guerriero, C Micheletto
BACKGROUND: The increase of basement membrane thickness (BMAT) represents a structural feature described as commonly characterizing airway remodelling in asthma, even if the non-atopic condition had been investigated only episodically from this point of view. Gastrooesophageal-reflux is a pathological condition which can frequently cause and/or sustain asthma in non-atopic individuals. OBJECTIVES: The aim of the study was to measure BMT; some inflammatory mediators in BAL; cys-leucotrienes (LTE4) in urine; e-NO, and BHR to Methacholine (MCh) in mild atopic and in mild non-atopic, GER-related asthma...
December 2012: European Annals of Allergy and Clinical Immunology
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