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https://www.readbyqxmd.com/read/29149668/parental-knowledge-and-attitudes-towards-epilepsy-a-study-from-jordan
#1
Amira Masri, Samah Aburahma, Aisha Khasawneh, Abdelkarim Al Qudah, Omar Nafi, Miral Al Momani, Faisal Khatib
PURPOSE: To explore the knowledge, attitudes and behaviors of parents whose children were diagnosed with epilepsy. METHODS: Cross-sectional questionnaire based study of parents who accompanied their children with epilepsy to the child neurology clinics at three university hospitals in Jordan. RESULTS: Most parents (427, 90.3%) knew that epilepsy is not related to a psychiatric disease. Approximately half of the parents (245, 51.8%) used the internet as their source of knowledge, and most used Arabic websites...
November 8, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29147869/hematological-adverse-effects-in-breast-cancer-patients-treated-with-cyclin-dependent-kinase-4-and-6-inhibitors-a-systematic-review-and-meta-analysis
#2
REVIEW
Loay Kassem, Kyrillus S Shohdy, Shaimaa Lasheen, Omar Abdel-Rahman, Thomas Bachelot
BACKGROUND: The introduction of specific cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors significantly improved progression-free survival in hormone receptor-positive metastatic breast cancer. CDK 4/6 inhibitors induce cell cycle arrest via liberating the tumor suppressor retinoblastoma protein from CDK4/6 inhibitory effect. Preliminary studies suggested an increase in the hematological toxicities which might affect the quality of life in such palliative setting. METHODS: We searched PubMed, ASCO, ESMO and San Antonio meeting databases for randomized phase II/III trials in metastatic breast cancer receiving CDK4/6 inhibitors with safety data provided on the incidence of hematological adverse effects...
November 16, 2017: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/29147476/sudden-cardiac-arrest-as-a-rare-presentation-of-myxedema-coma-case-report
#3
Divya Salhan, Deepak Sapkota, Prakash Verma, Saroj Kandel, Omar Abdulfattah, Antony Lixon, Deribe Zwenge, Frances Schmidt
Myxedema coma is a decompensated hypothyroidism which occurs due to long-standing, undiagnosed, or untreated hypothyroidism. Untreated hypothyroidism is known to affect almost all organs including the heart. It is associated with a decrease in cardiac output, stroke volume due to decreased myocardial contractility, and an increase in systemic vascular resistance. It can cause cardiac arrhythmias and the most commonly seen conduction abnormalities are sinus bradycardia, heart block, ventricular tachycardia, and torsade de pointes...
2017: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/29146857/whole-genome-sequence-of-salmonella-enterica-subsp-enterica-serovar-typhimurium-strain-upm-260-isolated-from-a-broiler-chicken-in-perak-malaysia
#4
Najwa Syahirah Roslan, Shagufta Jabeen, Nurulfiza Mat Isa, Abdul Rahman Omar, Mohd Hair Bejo, Aini Ideris
Salmonella enterica subsp. enterica serovar Typhimurium is one of several well-categorized Salmonella serotypes recognized globally. Here, we report the whole-genome sequence of S Typhimurium strain UPM 260, isolated from a broiler chicken.
November 16, 2017: Genome Announcements
https://www.readbyqxmd.com/read/29146419/syncope-on-presentation-is-a-surrogate-for-submassive-and-massive-acute-pulmonary-embolism
#5
Hesham R Omar, Mehdi Mirsaeidi, Michael B Weinstock, Garett Enten, Devanand Mangar, Enrico M Camporesi
INTRODUCTION: There are conflicting data regarding the prognostic value of syncope in patients with acute pulmonary embolism (APE). METHODS: We retrospectively reviewed data of 552 consecutive adults with computed tomography pulmonary angiogram-confirmed APE to determine the correlates and outcome of the occurrence of syncope at the time of presentation. RESULTS: Among 552 subjects with APE (mean age 54years, 47% men), syncope occurred in 12...
November 7, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29143830/gramicidin-ion-channels-in-a-lipid-bilayer-supported-on-polyelectrolyte-multilayer-films-an-electrochemical-impedance-study
#6
Eleftheria Diamanti, Eduart Gutiérrez-Pineda, Nikolaos Politakos, Patrizia Andreozzi, María José Rodriguez-Presa, Wolfgang Knoll, Omar Azzaroni, Claudio A Gervasi, Sergio E Moya
Supported membranes on polymer cushions are of fundamental interest as models for cell membranes. The use of polyelectrolyte multilayers (PEMs) assembled by the layer by layer (LbL) technique as supports for a bilayer allows for easy integration of the lipid bilayer on surfaces and devices and for nanoscale tunable spacing of the lipid bilayer. Controlling ionic permeability in lipid bilayers supported on PEMs triggers potential applications in sensing and as models for transport phenomena in cell membranes...
November 16, 2017: Soft Matter
https://www.readbyqxmd.com/read/29143220/validation-of-the-8th-ajcc-prognostic-staging-system-for-breast-cancer-in-a-population-based-setting
#7
Omar Abdel-Rahman
OBJECTIVES: To validate the newly proposed American Joint Committee on Cancer (AJCC) prognostic staging system for breast cancer. METHODS: Surveillance, epidemiology, and end results (SEER) database (2010-2014) was accessed. Cumulative incidence function was conducted (through assessment of sub-distribution hazard) according to both anatomical and prognostic stages. Likewise, Cox cause-specific hazard ratio with pairwise hazard ratio comparisons were also assessed for both anatomical and prognostic stages...
November 15, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29143168/limited-influence-of-blunt-aortic-injuries-on-the-outcome-of-polytraumatized-patients-a-matched-pair-analysis
#8
A Omar, C Macke, M Winkelmann, E Beckmann, P Mommsen, C Schröter, C Krettek, Christian Zeckey
INTRODUCTION: Traumatic lesions of great vessels such as the aorta are life-threatening injuries. There is limited evidence about the influence of traumatic aortic injuries in multiple trauma patients in particular with regard to posttraumatic complications. The aim of this study was to evaluate the influence of blunt thoracic aortic injuries in multiple trauma patients compared to a multiple trauma cohort without this specific injury. In addition, the safety of Thoracic Endovascular Aortic Repair (TEVAR) in multiple trauma patients was analyzed...
November 15, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29142491/impact-of-remote-ischemic-postconditioning-during-primary-percutaneous-coronary-intervention-on-left-ventricular-remodeling-after-anterior-wall-st-segment-elevation-myocardial-infarction-a-single-center-experience
#9
Ayman Elbadawi, Omar Awad, Ramy Raymond, Haytham Badran, Ahmad E Mostafa, Marwan Saad
The role of remote ischemic postconditioning (RIPostC) in improving left ventricular (LV) remodeling after primary percutaneous coronary intervention (PCI) is not well established. To determine the efficacy and safety of RIPostC in improving LV remodeling and cardiovascular outcomes after primary PCI for anterior ST-elevation myocardial infarction (STEMI). Seventy-one patients with anterior STEMI were randomized to primary PCI with RIPostC protocol ( n  = 36) versus conventional primary PCI ( n  = 35)...
December 2017: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/29142089/motor-cognitive-and-functional-declines-contribute-to-a-single-progressive-factor-in-early-hd
#10
Scott A Schobel, Giuseppe Palermo, Peggy Auinger, Jeffrey D Long, Shiyang Ma, Omar S Khwaja, Dylan Trundell, Merit Cudkowicz, Steven Hersch, Cristina Sampaio, E Ray Dorsey, Blair R Leavitt, Karl D Kieburtz, Jeffrey J Sevigny, Douglas R Langbehn, Sarah J Tabrizi
OBJECTIVE: To identify an improved measure of clinical progression in early Huntington disease (HD) using data from prospective observational cohort studies and placebo group data from randomized double-blind clinical trials. METHODS: We studied Unified Huntington Disease Rating Scale (UHDRS) and non-UHDRS clinical measures and brain measures of progressive atrophy in 1,668 individuals with early HD followed up prospectively for up to 30 to 36 months of longitudinal clinical follow-up...
November 15, 2017: Neurology
https://www.readbyqxmd.com/read/29141714/falciparum-malaria-outbreak-in-sabah-linked-to-an-immigrant-rubber-tapper
#11
Saffree Mohammad Jeffree, Kamruddin Ahmed, Nazarudin Safian, Rohaizat Hassan, Omar Mihat, Khamisah Awang Lukman, Shamsul Bahari Shamsudin, Fadzilah Kamaludin
Sabah is a Malaysian state situated in the northern part of Borneo, and it is endemic for malaria. The incidence of malaria is the lowest (0.05/1,000 population) in Penampang districts of Sabah. In June 26, 2012, two Plasmodium falciparum malaria cases were notified to public health department from a village in Penampang. Immediate investigation was initiated to identify the risk factors and to institute control measures. We performed active case finding by asking household members of all houses in the village regarding malaria symptoms and by examining blood smears...
November 6, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29140955/on-line-ratings-of-spine-surgeons-analysis-of-208-surgeons
#12
Jun Zhang, Adan Omar, Addisu Mesfin
STUDY DESIGN: Observational study OBJECTIVE.: To evaluate the online ratings of spine surgeons and variables that may affect online ratings. SUMMARY OF BACKGROUND DATA: Physician review websites (PRW) are rapidly growing for-profit businesses. Most Orthopaedic surgeons are rated on at least one PRW as are other surgical specialists. To date the online ratings of spine surgeons have not been evaluated. METHODS: Cervical Spine Research Society (CSRS) surgeon ratings on 5 physician rating websites were performed in April 2016: 'healthgrade...
November 14, 2017: Spine
https://www.readbyqxmd.com/read/29140497/integrating-complementary-and-traditional-practices-in-middle-eastern-supportive-cancer-care
#13
Eran Ben-Arye, Noah Samuels, Michel Daher, Ibrahim Turker, Omar Nimri, Maryam Rassouli, Michael Silbermann
The Middle East is a promising arena in which researchers can explore the interchange between cross-cultural traditional medicine and supportive cancer care, as provided within an integrative oncology setting. Integrative oncology research and clinical practice in this part of the world have been focusing, for the most part, on the use of herbal medicine and mind-body-spiritual modalities, both of which are deeply rooted in traditional medical care. A regional, multinational, and interdisciplinary collaboration is currently being undertaken as part of the academic activities of the Middle-East Research Group in Integrative Oncology (MERGIO)...
November 1, 2017: Journal of the National Cancer Institute. Monographs
https://www.readbyqxmd.com/read/29140385/virtual-treatment-planning-for-implant-retained-nasal-prosthesis-a-clinical-report
#14
Muaiyed Mahmoud Buzayan, Norsiah Binti Yunu, Ha Kien Oon, Omar Tawfiq
Osseointegrated craniofacial implants have improved retention and patients' perceptions of implant-retained nasal prostheses; however, the determination of the available bone sites for implant placement post-rhinectomy is difficult. This case report describes the use of cone beam computed tomography scanning and computer-assisted virtual planning in conjunction with digital photographs for rehabilitation of a facial defect with an implant-retained silicon nasal prosthesis. Two implants were planned in the anatomical area with adequate bone volume to achieve favorable cosmetic outcomes and accessibility for hygiene maintenance...
November 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29139601/utility-of-the-acc-aha-lesion-classification-as-a-predictor-of-procedural-30-day-and-12-month-outcomes-in-the-contemporary-percutaneous-coronary-intervention-era
#15
James Theuerle, Matias B Yudi, Omar Farouque, Nick Andrianopoulos, Peter Scott, Andrew E Ajani, Angela Brennan, Stephen J Duffy, Christopher M Reid, David J Clark
BACKGROUND: Correlations between the ACC/AHA coronary lesion classification and clinical outcomes in the contemporary percutaneous coronary intervention (PCI) era are not well established. METHODS: We analyzed clinical characteristics and outcomes according to ACC/AHA lesion classification (A, B1, B2, C) in 13,701 consecutive patients from the Melbourne Interventional Group (MIG) registry. Patients presenting with STEMI, cardiogenic shock and out-of-hospital cardiac arrest were excluded...
November 15, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29139528/assembly-of-small-molecule-surfactants-at-highly-dynamic-air-water-interfaces
#16
Omar T Mansour, Beatrice Cattoz, Manon Beaube, Morganne Montagnon, Richard K Heenan, Ralf Schweins, Marie-Sousai Appavou, Peter C Griffiths
Small-angle neutron scattering has been used to probe the interfacial structure of foams stabilised by small molecule surfactants at concentrations well below their critical micelle concentration. The data for wet foams showed a pronounced Q(-4) dependence at low Q and noticeable inflexions over the mid Q range. These features were found to be dependent on the surfactant structure (mainly the alkyl chain length) with various inflexions across the measured Q range as a function of the chain length but independent of factors such as concentration and foam age/height...
November 15, 2017: Soft Matter
https://www.readbyqxmd.com/read/29138878/higher-cost-of-hospitalizations-for-non-cardiac-diagnoses-in-adults-with-congenital-heart-disease
#17
Michael D Seckeler, Ian D Thomas, Jennifer Andrews, Omar Meziab, Tabitha Moe, Elissa Heller, Scott E Klewer
Adults with congenital heart disease (CHD) are a rapidly increasing population and their impact on healthcare resources is not fully understood. The purpose of this study was to describe the costs of hospitalizations for non-cardiac disease for adults with CHD. We conducted a retrospective review of hospital discharge data from the University HealthSystem Consortium Clinical Data Base/Resource Manager from January 2011 through December 2013. Patients were ≥ 18 years old at admission with any ICD-9 code for moderate or high severity CHD; cardiac surgical admissions were excluded...
November 15, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29138571/timed-up-and-go-test-combined-with-self-rated-multifactorial-questionnaire-on-falls-risk-and-sociodemographic-factors-predicts-falls-among-community-dwelling-older-adults-better-than-the-timed-up-and-go-test-on-its-own
#18
Azianah Ibrahim, Devinder Kaur Ajit Singh, Suzana Shahar, Mohd Azahadi Omar
Background: Early detection of falls risk among older adults using simple tools may assist in fall prevention strategies. The aim of this study was to identify the best parameters associated with previous falls, either the timed up and go (TUG) test combined with sociodemographic factors and a self-rated multifactorial questionnaire (SRMQ) on falls risk or the TUG on its own. Falls risk was determined based on parameters associated with previous falls. Design: This was a retrospective cohort study...
2017: Journal of Multidisciplinary Healthcare
https://www.readbyqxmd.com/read/29138540/a-qualitative-study-exploring-issues-related-to-medication-management-in-residential-aged-care-facilities
#19
Mariani Ahmad Nizaruddin, Marhanis-Salihah Omar, Adliah Mhd-Ali, Mohd Makmor-Bakry
Background: Globally, the population of older people is on the rise. As families are burdened with the high cost of care for aging members, demand is increasing for medical care and nursing homes. Thus, medication management is crucial to ensure that residents in a care center benefit and assist the management of the care center in reducing the burden of health care. This study is aimed to qualitatively explore issues related to medication management in residential aged care facilities (RACFs)...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29138316/germline-cas9-expression-yields-highly-efficient-genome-engineering-in-a-major-worldwide-disease-vector-aedes-aegypti
#20
Ming Li, Michelle Bui, Ting Yang, Christian S Bowman, Bradley J White, Omar S Akbari
The development of CRISPR/Cas9 technologies has dramatically increased the accessibility and efficiency of genome editing in many organisms. In general, in vivo germline expression of Cas9 results in substantially higher activity than embryonic injection. However, no transgenic lines expressing Cas9 have been developed for the major mosquito disease vector Aedes aegypti Here, we describe the generation of multiple stable, transgenic Ae. aegypti strains expressing Cas9 in the germline, resulting in dramatic improvements in both the consistency and efficiency of genome modifications using CRISPR...
November 14, 2017: Proceedings of the National Academy of Sciences of the United States of America
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