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Keywords risk evaluation in coronary sy...

risk evaluation in coronary syndrome

https://read.qxmd.com/read/38453426/net-clinical-benefit-of-extended-dual-pathway-inhibition-according-to-baseline-risk-in-patients-with-chronic-coronary-syndrome-a-compass-substudy
#21
JOURNAL ARTICLE
Morten Würtz, Kevin Kris Warnakula Olesen, Deepak L Bhatt, Salim Yusuf, Eva Muehlhofer, John W Eikelboom, Michael Maeng
AIMS: Guidelines recommend extended dual pathway inhibition (DPI) with aspirin and rivaroxaban in patients with chronic coronary syndrome (CCS) at high ischemic risk. The CHADS-P2A2RC score improves risk prediction and enables antithrombotic treatment allocation in these patients. This study evaluated the net clinical benefit of DPI treatment according to baseline risk as classified by the CHADS-P2A2RC score in patients with CCS included in the COMPASS trial. METHODS: COMPASS patients with CCS (n = 14 670), randomized to aspirin alone or DPI, were stratified according to cardiovascular risk using the CHADS-P2A2RC score...
March 7, 2024: European Heart Journal. Cardiovascular Pharmacotherapy
https://read.qxmd.com/read/38453013/comparison-of-long-term-prognoses-of-percutaneous-coronary-intervention-via-distal-transradial-and-conventional-transradial-access-for-acute-coronary-syndrome
#22
JOURNAL ARTICLE
Lingxia Xu, Wei Lu, Ganwei Shi, Wenhua Li, Jianqiang Xiao, Anni Yang, Feng Li, Gaojun Cai
BACKGROUND: Distal transradial access (dTRA) has recently emerged as a new vascular access alternative for coronary angiography (CAG) and/or percutaneous coronary intervention (PCI). However, published data on long-term mortality and major adverse cardiac events after PCI via dTRA are inconclusive. The aim of this study was to compare the long-term prognoses of PCI via dTRA and conventional transradial access (cTRA) for acute coronary syndrome (ACS) after 1-3 years of follow-up. METHODS: Patients who were diagnosed with ACS and underwent PCI between January 1, 2020, and December 31, 2021, were retrospectively enrolled...
March 5, 2024: Hellenic Journal of Cardiology: HJC
https://read.qxmd.com/read/38443803/prevalence-clinical-features-and-prognosis-of-familial-hypercholesterolemia-in-chinese-han-patients-with-acute-coronary-syndrome-after-a-coronary-event-a-retrospective-observational-study
#23
JOURNAL ARTICLE
Huijuan Kou, Hongtao Wang, Peng Liu, Xin Wang, Wenjing Zhu, Wei Jiang, Xiaojun Hu, Jie Deng
BACKGROUND: Familial hypercholesterolemia (FH) is an autosomal semi-dominant disease, characterized by markedly elevated levels of low-density lipoprotein cholesterol (LDL-c) from conception and accelerated atherosclerotic cardiovascular disease, often resulting in early death. The aim of this study was to evaluate the prevalence of clinically defined FH in Chinese Han patients with acute coronary syndrome (ACS) and compare the long-term prognosis of ACS patients with and without FH receiving lipid-lowering therapy containing statins after a coronary event...
March 5, 2024: BMC Cardiovascular Disorders
https://read.qxmd.com/read/38442927/-expression-and-diagnostic-value-of-growth-differentiation-factor-15-in-patients-with-septic-cardiomyopathy
#24
JOURNAL ARTICLE
Lin Wang, Xiaoyan Li, Lizhong Zhang, Yuan Sun
OBJECTIVE: To explore the expression of growth differentiation factor 15 (GDF15) in patients with septic cardiomyopathy and its value in the diagnosis of septic cardiomyopathy. METHODS: A observational study was conducted. Fifty patients with septic cardiomyopathy admitted to Shanxi Bethune Hospital from May 2022 to March 2023 were selected as the experimental group. Forty-six patients with acute coronary syndrome (ACS) in the same period were selected as the case control group...
February 2024: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://read.qxmd.com/read/38440007/evaluating-the-differential-risk-of-contrast-induced-nephropathy-among-diabetic-and-non-diabetic-patients-following-percutaneous-coronary-intervention
#25
JOURNAL ARTICLE
Fahad R Khan, Tariq Nawaz, Wasim Sajjad, Sadam Hussain, Muhammad Amin, Hassan Ali
Background Contrast-induced nephropathy (CIN) significantly complicates percutaneous coronary intervention (PCI), with a higher prevalence in diabetic patients. This study compares the incidence of CIN in diabetic and non-diabetic patients undergoing PCI. Material and methods Conducted at Lady Reading Hospital, Peshawar, PAK, from January to December 2023, this observational study involved 450 adult patients with coronary artery disease (CAD) undergoing PCI. The cohort was categorized based on diabetes status, excluding patients with chronic kidney disease and those on renal replacement therapy...
February 2024: Curēus
https://read.qxmd.com/read/38436608/accuracy-of-death-risk-prediction-models-for-acute-coronary-syndrome-patients-a-systematic-review-and-meta-analysis
#26
JOURNAL ARTICLE
Jifang Cheng, Yike Wang, Jiantong Sheng, Wang Ya, Zhu Xia
INTRODUCTION: This study systematically evaluates the accuracy of several death risk prediction models for patients with acute coronary syndrome (ACS) through evidence-based methods. We identify the most accurate and effective ACS death risk prediction model and provide an evidence-based basis for clinical healthcare personnel to evaluate their choice of death risk prediction model for ACS patients. EVIDENCE ACQUISITION: An evidence-based approach was used to study the current death risk prediction model for ACS...
March 4, 2024: Minerva cardiology and angiology
https://read.qxmd.com/read/38436365/one-month-dapt-with-ticagrelor-and-aspirin-for-patients-undergoing-coronary-artery-bypass-grafting-rationale-and-design-of-the-randomised-multicentre-double-blind-placebo-controlled-odin-trial
#27
RANDOMIZED CONTROLLED TRIAL
Sigrid Sandner, Mario Gaudino, Bjorn Redfors, Dominick J Angiolillo, Ori Ben-Yehuda, Deepak L Bhatt, Stephen E Fremes, Andre Lamy, Riccardo Marano, Roxana Mehran, Stuart Pocock, Sunil V Rao, John A Spertus, Jonathan W Weinsaft, George Wells, Marc Ruel
The optimal antiplatelet strategy after coronary artery bypass graft (CABG) surgery in patients with chronic coronary syndromes (CCS) is unclear. Adding the P2Y12 inhibitor, ticagrelor, to low-dose aspirin for 1 year is associated with a reduction in graft failure, particularly saphenous vein grafts, at the expense of an increased risk of clinically important bleeding. As the risk of thrombotic graft failure and ischaemic events is highest early after CABG surgery, a better risk-to-benefit profile may be attained with short-term dual antiplatelet therapy followed by single antiplatelet therapy...
March 4, 2024: EuroIntervention
https://read.qxmd.com/read/38434565/nomogram-developed-with-apoa5-genetic-variant-rs662799-and-clinical-characteristics-predicting-risk-of-essential-hypertension-in-a-chinese-population
#28
JOURNAL ARTICLE
Dilihumaer Abulaiti, Shajidan Abudureyimu, Hui Li, Yan Cao, Ying Gao
BACKGROUND: The apolipoprotein A5 ( APOA5 ) gene has been identified as a key regulatory factor in triglyceride (TG) metabolism and plasma lipid levels. Genetic polymorphisms of APOA5 have been linked to an elevated risk of atherosclerosis, metabolic syndrome, stroke, and coronary artery disease. The rs662799 variant is a single nucleotide polymorphism (SNP) that occurs at a specific position within the APOA5 gene. However, the association between rs662799 polymorphism and essential hypertension (EHT) remains unclear...
February 15, 2024: Cardiovascular Diagnosis and Therapy
https://read.qxmd.com/read/38428900/time-interval-of-esomeprazole-and-dual-antiplatelet-therapy-in-patients-with-cardiocerebrovascular-diseases
#29
JOURNAL ARTICLE
Hyunsoo Kim, Moon-Hwa Park, Joon-Tae Kim
Dual antiplatelet therapy (DAPT) with the combination of clopidogrel and aspirin is recommended for preventing secondary ischemic events in patients with acute coronary syndrome (ACS) or acute ischemic stroke (AIS). Proton pump inhibitors (PPIs) are suggested as preventive treatment for these patients. Due to clopidogrel-PPI interactions, separating their administration might be considered. However, a paucity of studies has been conducted to investigate the outcome differences between concurrent and interval-based use in ACS and AIS patients...
March 1, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38425675/executive-summary-of-the-hellenic-atherosclerosis-society-guidelines-for-the-diagnosis-and-treatment-of-dyslipidemias-2023
#30
REVIEW
N Katsiki, Td Filippatos, C Vlachopoulos, D Panagiotakos, H Milionis, A Tselepis, A Garoufi, L Rallidis, D Richter, T Nomikos, G Kolovou, K Kypreos, C Chrysohoou, K Tziomalos, I Skoumas, I Koutagiar, A Attilakos, M Papagianni, C Boutari, V Kotsis, C Pitsavos, M Elisaf, K Tsioufis, E Liberopoulos
Atherosclerotic cardiovascular disease (ASCVD) remains the main cause of death worldwide, and thus its prevention, early diagnosis and treatment is of paramount importance. Dyslipidemia represents a major ASCVD risk factor that should be adequately managed at different clinical settings. 2023 guidelines of the Hellenic Atherosclerosis Society focus on the assessment of ASCVD risk, laboratory evaluation of dyslipidemias, new and emerging lipid-lowering drugs, as well as diagnosis and treatment of lipid disorders in women, the elderly and in patients with familial hypercholesterolemia, acute coronary syndromes, heart failure, stroke, chronic kidney disease, diabetes, autoimmune diseases, and non-alcoholic fatty liver disease...
March 2024: Atheroscler Plus
https://read.qxmd.com/read/38411209/-evaluation-of-beta-2-microglobulin-and-neuron-specific-enolase-as-prognostic-factors-in-patients-over-65%C3%A2-years-of-age-with-frailty-syndrome-hospitalized-for-acute-coronary-syndrome
#31
JOURNAL ARTICLE
Wojciech Nowak, Ilona Kowalik, Janina Stępińska
BACKGROUND: The aim of the study is to assess the value of beta-2-microglobulin (B2M) and neuron-specific enolase (NSE) as prognostic factors in the population of patients over 65 years of age with frailty hospitalized due to acute coronary syndrome (ACS). METHODS: Patients aged ≥65 years with ACS were included. Assessment of frailty was carried out using the FRAIL scale. The measurement of NSE and B2M was carried out three times during hospitalization: (1) at the time of admission, (2) on the second day of hospitalization, (3) on the seventh day of hospitalization, or the day of discharge if it was before the seventh day...
February 20, 2024: Coronary Artery Disease
https://read.qxmd.com/read/38407428/correlation-of-osteopontin-hormone-with-timi-score-and-cardiac-markers-in-patients-with-acute-coronary-syndrome-presenting-with-chest-pain
#32
JOURNAL ARTICLE
Ayşe Şule Akan, Ibrahim Özlü
AIM: Rapid evaluation of patients with acute coronary syndrome (ACS) attending the emergency service under emergency room conditions and using appropriate risk scoring would improve treatment success. Calcium levels accumulate in the tissue in people with coronary artery disease and this has been found to correlate with osteopontin levels in some studies. It is predicted that osteopontin level could be used as a biomarker to detect coronary artery calcification. In this study, we aimed to evaluate the use of osteopontin levels in the differential diagnosis of ACS in conjunction with cardiac troponin I (cTnI) levels, and HEART (history, ECG, age, risk factors, troponin) and thrombolysis in myocardial infarction (TIMI) scores in patients with chest pain who attended the emergency service...
February 16, 2024: Cardiovascular Journal of Africa
https://read.qxmd.com/read/38402570/prognostic-significance-of-il-18-in-acute-coronary-syndrome-patients
#33
JOURNAL ARTICLE
Chenchun Xiong, Qiaoting Yu, Feng Gao, Song Liu, Jianhui Zhang, Tianyi Ma, Suifeng Liu
BACKGROUND: After acute coronary syndrome (ACS), inflammation aids healing but may harm the heart. Interleukin (IL)-18 and IL-1β are pivotal proinflammatory cytokines released during pyroptosis, a process that initiates and sustains inflammation. This study aimed to evaluate the levels of circulating IL-18 and IL-1β during the progression of ACS and to determine their association with subsequent clinical events in ACS patients. HYPOTHESIS: Circulating levels of IL-18 and IL-1β are associated with subsequent clinical events in ACS patients...
February 2024: Clinical Cardiology
https://read.qxmd.com/read/38402557/a-higher-non-hdl-c-hdl-c-ratio-was-associated-with-an-increased-risk-of-progression-of-nonculprit-coronary-lesion-in-patients-with-acute-coronary-syndrome-undergoing-percutaneous-coronary-intervention
#34
JOURNAL ARTICLE
Jiamin Liu, Li Zhao, Yazhou Zhang, Lili Wang, Qianqian Feng, Jing Cui, Wenhong Zhang, Jianyong Zheng, Dan Wang, Fengjiao Zhao, Jiangchun He, Yu Chen
BACKGROUND: The ratio of nonhigh-density lipoprotein cholesterol (non-HDL-C) to high-density lipoprotein cholesterol (HDL-C) has been shown associated with various metabolic diseases and atherosclerosis in primary prevention. However, there is limited evidence on the relationship between the non-HDL-C/HDL-C ratio and progression of nonculprit coronary lesion (NCCL) after percutaneous coronary intervention (PCI). HYPOTHESIS: Our study aimed to investigate the potential association between the non-HDL-C/HDL-C ratio and NCCL progression in patients with acute coronary syndrome (ACS) undergoing PCI...
February 2024: Clinical Cardiology
https://read.qxmd.com/read/38398712/acute-myocardial-infarction-during-the-covid-19-pandemic-long-term-outcomes-and-prognosis-a-systematic-review
#35
REVIEW
Marius Rus, Adriana Ioana Ardelean, Felicia Liana Andronie-Cioara, Georgiana Carmen Filimon
Coronavirus disease 2019 (COVID-19) was a global pandemic with high mortality and morbidity that led to an increased health burden all over the world. Although the virus mostly affects the pulmonary tract, cardiovascular implications are often observed among COVID-19 patients and are predictive of poor outcomes. Increased values of myocardial biomarkers such as troponin I or NT-proBNP were proven to be risk factors for respiratory failure. Although the risk of acute coronary syndromes (ACSs) was greater in the acute phase of COVID-19, there were lower rates of hospitalization for ACSs, due to patients' hesitation in presenting at the hospital...
January 31, 2024: Life
https://read.qxmd.com/read/38392281/the-effect-of-sleep-quality-on-coronary-lesion-severity-and-prognosis-in-the-young-acute-coronary-syndrome-population
#36
JOURNAL ARTICLE
Jiaxin Yang, Kexin Wang, Wenjie Wang, Jialong Niu, Xiaoli Liu, Hua Shen, Yan Sun, Hailong Ge, Hongya Han
This study aimed to explore the effect of long-term (≥1 year) sleep quality on coronary lesion complexity and cardiovascular prognosis in young acute coronary syndrome (ACS) patients. We consecutively recruited young patients aged from 18 to 44 years old with first-episode ACS and significant epicardial stenosis on coronary angiography from January 2016 to January 2017. Coronary lesion complexity was evaluated based on SYNTAX scores. Long-term sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) (PSQI ≤ 5 and PSQI > 5 groups)...
February 19, 2024: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/38384894/optimal-lesion-preparation-before-implantation-of-a-magmaris-bioresorbable-scaffold-in-patients-with-coronary-artery-stenosis-rationale-design-and-methodology-of-the-optimis-study
#37
JOURNAL ARTICLE
Kirstine Nørregaard Hansen, Akiko Maehara, Manijeh Noori, Jens Trøan, Christian Oliver Fallesen, Mikkel Hougaard, Julia Ellert-Gregersen, Karsten Tange Veien, Anders Junker, Henrik Steen Hansen, Jens Flensted Lassen, Lisette Okkels Jensen
INTRODUCTION: Percutaneous coronary intervention with implantation of a bioresorbable scaffold (BRS) provide the vessel support for a limited period allowing the vessel to restore normal vasomotion after degradation of the BRS, opposed to treatment with drug-eluting stents where the metal persist in the vessel wall. Late lumen loss and reduction in lumen area after implantation have been reported. The purpose of this study was to investigate whether intense pre-dilatation before BRS implantation resulted in less reduction of minimal lumen area at 6- and 12-month follow-up after implantation of a Magmaris BRS (MgBRS)...
April 2024: Contemporary Clinical Trials Communications
https://read.qxmd.com/read/38384448/the-impact-of-patient-adherence-to-dual-antiplatelet-medication-following-percutaneous-coronary-intervention-on-the-occurrence-of-adverse-cardiovascular-events
#38
JOURNAL ARTICLE
J A Mansurova, Andrey Orekhov, A S Zhunuspekova, A A Kassymova, L K Karazhanova
BACKGROUND: The objective of this study is to examine the impact of medication adherence on the timing of non-cardiovascular serious events (NCDS) onset in patients with acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI). METHODS: This prospective study was conducted at a single center and involved 220 ACS patients who underwent sequential PCI with stenting. The Morisky Green Levine Medication Adherence Scale was employed to assess adherence to dual antiplatelet therapy (DAPT) and its impact on NCDS occurrence...
2024: Patient Preference and Adherence
https://read.qxmd.com/read/38382851/the-predictive-value-of-serum-dickkopf-1-dickkopf-3-level-to-coronary-artery-disease-and-acute-coronary-syndrome
#39
JOURNAL ARTICLE
Panpan Xu, Yu Cao, Shuai Zhang, Xiaoling Liu, Meng Zhang, Cheng Zhang
BACKGROUND: Previous studies have already confirmed the association between Dickkopf (Dkk) protein and the occurrence and progression of atherosclerosis. However, there is limited clinical evidence regarding the serum levels of Dickkopf-1 (Dkk1) and Dickkopf-3 (Dkk3) in relation to atherosclerotic cardiovascular disease (ASCVD), particularly acute coronary syndrome (ACS). MATERIALS AND METHODS: A total of 88 healthy volunteers and 280 patients with coronary artery disease (CAD) undergoing coronary angiography for angina between October 2021 and October 2022, including 96 cases of stable angina (SA), 96 of unstable angina (UA) and 88 of acute myocardial infarction (AMI) were included finally...
February 19, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38381355/takotsubo-cardiomyopathy-in-india-and-its-electrocardiography-ecg-comparison-to-myocardial-infarction
#40
JOURNAL ARTICLE
Tanisha Mishra, Rijushree Saha, Ganesh Paramasivam
BACKGROUND: Owing to the limited research on Takotsubo Cardiomyopathy (TCM) in Asia, we aim to evaluate in detail the clinical profiles, lab parameters, investigations, and major adverse cardiovascular events (MACE) seen in patients with TCM in the Indian subcontinent. Additionally, we have compared the electrocardiographic findings of patients with TCM to those of patients with myocardial infarction (MI). RESULTS: The average age of the patients affected was found to be 60 ± 11 years...
February 21, 2024: Egyptian Heart Journal: EHJ
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