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Silver fluoride

M L Mei, E C M Lo, C H Chu
Unlike other fluoride-based caries preventive agents, silver diamine fluoride (SDF) can simultaneously prevent and arrest coronal and root dentine caries. The profound clinical success of SDF has drawn many clinicians and researchers to study the mechanism of SDF in arresting dentine caries. This critical review discusses how silver and fluoride contribute to caries arrest, in terms of their effects on bacteria as well as on the mineral and organic content of dentine. Silver interacts with bacterial cell membrane and bacterial enzymes, which can inhibit bacterial growth...
May 1, 2018: Journal of Dental Research
Yasmi O Crystal, Benjamin W Chaffee
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Silver diamine fluoride has efficacy in controlling caries progression in primary teeth: A systematic review and meta-analysis. Chibinski AC, Wambier LM, Feltrin J, Dourado Loguercio A, Stadler Wambier D, Reis A. Caries Res 2017;51:527-41. SOURCE OF FUNDING: This study was partially supported by the National Council for Scientific and Technological Development of Brazil under grants 304105/2013-9 and 305588/2014-1 TYPE OF STUDY/DESIGN: Systematic review with meta-analysis...
June 2018: Journal of Evidence-based Dental Practice
Mahmoud Sayed, Naoko Matsui, Noriko Hiraishi, Toru Nikaido, Michael F Burrow, Junji Tagami
This study evaluated the effect of Glutathione (GSH) bio-molecule on the reduction of enamel and dentin discoloration after application of 38% silver diammine fluoride solution (SDF). One hundred and twenty bovine teeth specimens were used. The enamel and dentin specimens were divided into three groups: (1) SDF only (control); (2) SDF followed by application of a potassium iodide solution (KI); and (3) SDF mixed with 20% GSH. Half the specimens were exposed to light and the remainder kept in dark conditions ( n = 10) Color changes were measured using a spectrophotometer at the following time intervals: before solution application (baseline) and immediately after application, then 3, 6, 24, 48, 72 h, and 7, 10 and 14 days...
April 29, 2018: International Journal of Molecular Sciences
Chen Zhang, Youjun Fan, Huayang Li, Yayuan Li, Lei Zhang, Shubo Cao, Shuangyang Kuang, Yongbin Zhao, Aihua Chen, Guang Zhu, Zhong Lin Wang
A fully rollable nanocomposite-based nanogenerator (NCG) is developed by integrating a lead-free piezoelectric hybrid layer with a type of nanofiber-supported silver nanowire (AgNW) network electrodes. The thin-film nanocomposite is composed of electroactive polyvinylidene fluoride (PVDF) polymer matrix and compositionally modified potassium sodium niobate-based nanoparticles (NPs) with a high piezoelectric coefficient (d33) of 53 pm/V, which is revealed by the piezoresponse force microscopy measurements. Under periodical agitation at a compressive force of 50 N and 1 Hz, the NCG can steadily render high electric output up to an open-circuit voltage of 18 V and a short-circuit current of 2...
April 27, 2018: ACS Nano
Ollie Yiru Yu, Irene Shuping Zhao, May Lei Mei, Edward Chin-Man Lo, Chun-Hung Chu
This study investigated the effect of 25% silver nitrate (AgNO₃) and 5% sodium fluoride (NaF) varnish with functionalized tri-calcium phosphate (fTCP) on a Streptococcus mutans ( S. mutans ) biofilm and dentine caries lesion. Demineralised dentine specimens were treated with 25% AgNO₃ and 5% NaF + fTCP (Group 1), 25% AgNO₃ and 5% NaF (Group 2), 25% AgNO₃ (Group 3), or water (Group 4). The specimens were subjected to a S. mutans biofilm challenge after treatment. The biofilm was then studied via scanning electron microscopy (SEM), confocal laser scanning microscopy (CLSM), and colony forming units (CFU)...
April 25, 2018: International Journal of Molecular Sciences
Romina Brignardello-Petersen
No abstract text is available yet for this article.
March 31, 2018: Journal of the American Dental Association
Romina Brignardello-Petersen
No abstract text is available yet for this article.
March 2, 2018: Journal of the American Dental Association
Donald L Chi, Peter Milgrom, Jane Gillette
Purpose: The purpose of this study was to use qualitative methods to describe the key lessons learned during the stakeholder engagement stage of planning a randomized clinical trial comparing outcomes of silver diamine fluoride (SDF) as an alternative to pit-and-fissure sealants in a school-based delivery system. Methods: Eighteen caregivers and community-based stakeholders with involvement in the school-based sealant program Sealants for Smiles from the state of Montana, were recruited for this qualitative study...
February 2018: Journal of Dental Hygiene: JDH
Nicholas B Gordon
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Parental perceptions and acceptance of silver diamine fluoride staining. Crystal YO, Janal MN, Hamilton DS, Niederman R. J Am Dent Assoc 2017; 148(7):510-8. SOURCE OF FUNDING: Grant from the National Institute on Minority Health and Health Disparities (NIMHD), National Institutes of Health; New York University Clinical and Translational Science Award; and National Center for Advancing Translational Science, National Institutes of Health TYPE OF STUDY/DESIGN: Cross-sectional...
March 2018: Journal of Evidence-based Dental Practice
Jaana Gold
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Silver Diamine Fluoride Has Efficacy in Controlling Caries Progression in Primary Teeth: A Systematic Review and Meta-Analysis. Chibinski AC, Wambier LM, Feltrin J, Loguercio AD, Wambier DS, Reis A. Caries Res 2017;51(5):527-41. SOURCE OF FUNDING: This study was partially supported by the Brazilian Government Organization-National Council for Scientific and Technological Development (CNPq)-under grants 304105/2013-9 and 305588/2014-1 TYPE OF STUDY/DESIGN: Systematic review and meta-analysis...
March 2018: Journal of Evidence-based Dental Practice
Harsh Dave, Neha Bhandari, Bhavya Mod, Ritesh Shukla, Alok Pandya
Cellulose paper based multifunctional nanoplatform shows great promise towards molecular sensing and diagnostics application due to their sustainability, biocompatibility, affordability, environmental appeal and broad chemical modification capabilities. Herein, we have effectively synthesized plasmonic silver-cellulose nanocomposite (SCN) using complete green and in situ approach using the hydroxyl groups of cellulose paper acting as the reducing agent and stabilizing agent. The fabricated SCN were investigated and characterized by SEM, UV-Vis, DLS, PXRD and EDX...
August 1, 2018: Journal of Nanoscience and Nanotechnology
Da-Ming Ren, Hua-Kun Huang, Yun Yu, Zeng-Tian Li, Li-Wang Jiang, Shui-Mei Chen, Kwok-Ho Lam, Bo Lin, Bo Shi, Fu-An He, Hui-Jun Wu
Nanofibrous silver (Ag)/poly(vinylidene fluoride) (PVDF) composite membranes were obtained from a two-step preparation method. In the first step, the electrospun silver nitrate (AgNO3)/PVDF membranes were prepared and the influence of the AgNO3 content on the electrospinning process was studied. According to scanning electron microscopy (SEM) results, when the electrospinning solution contained AgNO3 in the range between 3 to 7 wt.%, the nanofiber morphologies can be obtained. In the second step, the electrospun AgNO3/PVDF membranes were reduced by sodium borohydride to form the nanofibrous Ag/PVDF composite membranes...
May 1, 2018: Journal of Nanoscience and Nanotechnology
Yi-Ying Zhao, Qiang Chu, Xu-Er Shi, Xiao-Dong Zheng, Xiao-Ting Shen, Yan-Zhen Zhang
To address the controversial issue of the toxicity of dental alloys and silver nanoparticles in medical applications, an in vivo-like LO2 3-D model was constructed within polyvinylidene fluoride hollow fiber materials to mimic the microenvironment of liver tissue. The use of microscopy methods and the measurement of liver-specific functions optimized the model for best cell performances and also proved the superiority of the 3-D LO2 model when compared with the traditional monolayer model. Toxicity tests were conducted using the newly constructed model, finding that four dental castings coated with silver nanoparticles were toxic to human hepatocytes after cell viability assays...
2018: Journal of Zhejiang University. Science. B
Tahira Devji
No abstract text is available yet for this article.
April 2018: Journal of the American Dental Association
Xiaojun Wang, Yongming Wu
A copper-mediated oxidative isoperfluoropropylation of unactivated terminal alkenes with commercially available hexafluoropropylene (HFP) has been developed. With operational simplicity of the procedure and broad substrate applicability, this strategy provides a general and straightforward way for the construction of C(sp3 )-C3 F7 -i bonds. A variety of allylic isoperfluoropropylated compounds have been efficiently synthesized using this strategy.
February 15, 2018: Chemical Communications: Chem Comm
Gerd Göstemeyer, Anna Kohls, Sebastian Paris, Falk Schwendicke
Uncertainty exists as to how to best prevent root caries development. The aim of the present study was to compare sodium fluoride (NaF), chlorhexidine (CHX) and silver diamine fluoride (SDF) varnishes (V) and rinses (R) regarding their caries preventive effect in an artificial caries biofilm model. 140 bovine root dentin samples were cut, polished and embedded. Samples were allocated to seven treatment groups (n = 20/group): Four varnishes (applied once prior biofilm challenge): 38% SDF (SDFV), 35% CHX-varnish (CHXV), 22,600 ppm NaF-varnish (NaFV), placebo-varnish (PV); two rinses (applied once daily during biofilm challenge): 500 ppm NaF solution (NaFR), 0...
January 31, 2018: Odontology
Kitty Jieyi Chen, Sherry Shiqian Gao, Duangporn Duangthip, Edward Chin Man Lo, Chun Hung Chu
The latest national survey found that 70% of 5-year-old children in China had dental caries. The prevalence of early childhood caries (ECC) may not only be attributed to poor oral hygiene and unhealthy diet, but also to limited access to and availability of dental care. The prevailing preventive measures adopted by industrialised countries for ECC management are neither practical nor affordable in China. Hence, an alternative approach to ECC management is necessary. Atraumatic restorative treatment (ART) has been advocated because the simple and short operative time renders ART affordable...
January 30, 2018: Healthcare (Basel, Switzerland)
J A Horst
Medical management of caries is a distinct treatment philosophy that employs topical minimally invasive therapies that treat the disease and is not merely prevention. This strategy is justified as an alternative or supplement to traditional care by significant disease recurrence rates following comprehensive operative treatment under general anesthesia. Silver diamine fluoride (SDF) is one agent to enable effective noninvasive treatment. The announcement of breakthrough therapy designation by the Food and Drug Administration (FDA) suggests that SDF may become the first FDA-approved drug for treating caries...
February 2018: Advances in Dental Research
J O Burgess, P M Vaghela
Silver diamine fluoride (SDF) is a solution containing ionic silver, fluoride, and ammonia that arrests the progress of carious lesions and prevents the development of future caries. The silver particle extends into the dentin tubules and could create some bonding problems for subsequent composite resin restorations placed over SDF-treated darkened tooth structures. The fluoride penetrates deeper into the tooth with SDF as compared with other fluoride solutions, creating a fluoride reservoir in the tooth structure...
February 2018: Advances in Dental Research
D R Schwass, K M Lyons, R Love, G R Tompkins, C J Meledandri
A novel silver nanoparticle (AgNP) formulation was developed as a targeted application for the disinfection of carious dentine. Silver nitrate (AgNO3 ) was chemically reduced using sodium borohydrate (NaBH4 ) in the presence of sodium dodecyl sulfate (SDS) to form micelle aggregate structures containing monodisperse 6.7- to 9.2-nm stabilized AgNPs. AgNPs were characterized by measurement of electrical conductivity and dynamic light scattering, scanning electron microscopy, transmission electron microscopy, and inductively coupled plasma mass spectrometry...
February 2018: Advances in Dental Research
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