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Diamine silver fluoride

L Paglia
Despite the general advances in dental care, dental caries is still a global health problem affecting many children. Occlusal surfaces of first permanent molars are the most susceptible sites in the developing permanent dentition. Dentists should use sealants or fluoride varnish - as well as other means - to limit the onset of tooth decay. Application of sealants is a recommended procedure to prevent or control caries. Sealing occlusal surfaces of newly erupted permanent molars in children and teenagers delays caries onset up to 48 months compared with unsealed teeth...
September 2016: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
Karthik Selvaraj, Vidhya Sampath, V Sujatha, S Mahalaxmi
AIMS: The aim of this in vitro study was to comparatively evaluate the microshear bond strength (MSBS) of etch-and-rinse and self-etch (ER and SE) bonding systems to dentin pretreated with silver diamine fluoride/potassium iodide (SDF/KI) and nanoleakage at the resin-dentin interface using transmission electron microscope (TEM). SUBJECTS AND METHODS: Seventy-two dentin slabs of 3 mm thickness were prepared from extracted human permanent third molars and divided into four groups (n = 18) based on the dentin surface treatment as follows: (1) ER adhesive bonding without dentin pretreatment; (2) SDF/KI pretreatment of dentin followed by ER adhesive bonding; (3) SE adhesive bonding without dentin pretreatment; and (4) SDF/KI pretreatment of dentin followed by SE adhesive bonding...
July 2016: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
(no author information available yet)
The immediate application of potassium iodide to dental root caries treated with silver diamine fluoride improved the colour of the lesion from black to bright yellow, but this colour change was only short lived.
October 7, 2016: British Dental Journal
Ruichang Gao, Tong Shi, Xiangdong Liu, Mengqin Zhao, Henglin Cui, Li Yuan
BACKGROUND: Because proteases play an important role in the fermentation of fish sauce, the purification and characterization of an extracellular protease from the halophilic archaeon Halogranum rubrum was investigated. RESULTS: The molecular mass of the protease was estimated to be approximately 47 kDa based on sodium dodecyl sulfate polyacrylamide gel electropheresis (SDS-PAGE) and native-PAGE analysis. The optimum conditions for catalytic activity were pH 8.0 and 50 °C...
July 5, 2016: Journal of the Science of Food and Agriculture
Travis Nelson, Joanna M Scott, Yasmi O Crystal, Joel H Berg, Peter Milgrom
PURPOSE: The purpose of this study was to investigate practice, teaching, and perceived barriers to the use of silver diamine fluoride and other caries control agents in U.S. pediatric dentistry residency programs. METHODS: A 14-question survey regarding use and teaching of caries control agents was sent via email to residency program directors in 2015. Survey participants responded, using a web-based survey tool, by completing a paper and pencil survey instrument, or by interview...
2016: Pediatric Dentistry
Denise M Bowen
The purpose of Linking Research to Clinical Practice is to present evidence based information to clinical dental hygienists so that they can make informed decisions regarding patient treatment and recommendations. Each issue will feature a different topic area of importance to clinical dental hygienists with A BOTTOM LINE to translate the research findings into clinical application.
April 2016: Journal of Dental Hygiene: JDH
Di I Wu, Saalini Velamakanni, Joseph Denisson, Peter Yaman, James R Boynton, Petros Papagerakis
PURPOSE: The purpose of this study was to investigate the effect of silver diamine fluoride (SDF) on the microtensile bonding strength of resin composite to the dentin of primary molars. METHODS: Twelve primary molars were randomly assigned to either the control or the SDF groups, and microtensile bonding strength (mTBS) was measured. The surface morphology was evaluated by visual inspection and scanning electron microscopy (SEM) imaging. RESULTS: The mean±(SD) value of mTBS in the control and SDF group was 162...
March 2016: Pediatric Dentistry
May L Mei, Edward Chin-Man Lo, Chun-Hung Chu
The use of a topical fluoride solution, namely silver diamine fluoride (SDF), in dental treatment has been drawing increasing attention. SDF has been used in some countries in Asia, including Japan and China, as a caries-arresting and anti-hypersensitivity agent. It was recently cleared by the Food and Drug Administration in the United States as a fluoride to manage hypersensitive teeth. Topical application of SDF is a noninvasive procedure that is quick and simple to use. Promising results of laboratory studies and clinical trials have suggested that SDF is more effective than other fluoride agents to halt the caries process...
February 2016: Compendium of Continuing Education in Dentistry
Jeremy A Horst, Hellene Ellenikiotis, Peter L Milgrom
The Food and Drug Administration recently cleared silver diamine fluoride for reducing tooth sensitivity. Clinical trials document arrest and prevention of dental caries by silver diamine fluoride. This off-label use is now permissible and appropriate under U.S. law. A CDT code was approved for caries arresting medicaments for 2016 to facilitate documentation and billing. We present a systematic review, clinical indications, clinical protocol and consent procedure to guide application for caries arrest treatment...
January 2016: Journal of the California Dental Association
Sherry Shiqian Gao, Shinan Zhang, May Lei Mei, Edward Chin-Man Lo, Chun-Hung Chu
BACKGROUND: As a low-cost and easily operated treatment, the use of professionally applied topical fluoride was approved for preventing dental caries and remineralising early enamel caries or white spot lesions. It is also used to arrest dentine caries. The aim of this study is to investigate the clinical efficacy of professional fluoride therapy in remineralising and arresting caries in children. METHOD: A systematic search of publications from 1948 to 2014 was conducted using four databases: PubMed, Cochrane Library, ISI Web of Science and Embase...
2016: BMC Oral Health
May Lei Mei, Irene Shuping Zhao, Leticia Ito, Edward Chin-Man Lo, Chun-Hung Chu
PURPOSE: This study aimed to investigate the use of 38% silver diamine fluoride (SDF) as a treatment for preventing secondary caries in glass ionomer cement (GIC) and composite resin (CR) restorations. METHODS: Six extracted human sound premolars were collected. Four cavities (4 × 2 × 2 mm(3) ) were prepared on each premolar and then allocated to the following restoration groups: group 1, SDF conditioning and GIC restoration; group 2, GIC restoration; group 3, SDF conditioning and CR restoration; and group 4, CR restoration...
April 2016: International Dental Journal
Alan Deutsch
An alternate technique of care to prevent, arrest and manage root caries using aqueous silver fluoride followed by stannous fluoride (AgF+SnF2) in aged care is demonstrated by three case studies. With increasing age, the inability to maintain ones own oral care from dementia, illness or frailty and polypharmacy induced salivary gland hypofunction will result in dental caries becoming a progessively greater burden for the elderly. Future generations of elders will live longer and need to maintain many more teeth longer than earlier generations...
March 2016: Special Care in Dentistry
Chun-Hung Chu, Sherry Shiqian Gao, Samantha Ky Li, May Cm Wong, Edward Cm Lo
BACKGROUND: The application of 38 % silver diamine fluoride (SDF) has been shown to be effective in arresting early childhood caries (ECC). Since SDF is not available in certain countries, some dentists use adjunctive application of 25 % silver nitrate (AgNO3) and 5 % sodium fluoride (NaF) to arrest ECC. This randomised controlled trial will systematically compare the efficacy of a 25 % AgNO3 solution followed by 5 % NaF varnish with that of a 38 % SDF solution in arresting ECC when applied at half-yearly intervals over a 30-month period...
2015: Trials
Gaurav Sharma, Manjunath P Puranik, Sowmya K R
BACKGROUND: Dental caries is one of the most prevalent chronic oral diseases across the globe that can be both treated and prevented. Preventive management strategies can effectively arrest and even completely reverse the caries process. This article aimed to review the literature on different approaches explored towards arresting caries progression. MATERIALS AND METHODS: Literature search of publications in Pubmed/Medline was carried out. Total 73 articles including clinical trials, invitro studies, case reports and review articles were reviewed...
May 2015: Journal of Clinical and Diagnostic Research: JCDR
Linlin Han, Takashi Okiji
PURPOSE: To compare the dentin tubule-occluding ability of fluoroaluminocalciumsilicate-based (Nanoseal), calcium phosphate-based (Teethmate Desensitizer), resin-containing oxalate (MS Coat ONE) and diamine silver fluoride (Saforide) dentin desensitizers using artificially demineralized bovine dentin. METHODS: Simulated hypersensitive dentin was created using cervical dentin sections derived from bovine incisors using phosphoric acid etching followed by polishing with a paste containing hydroxyapatite...
April 2015: American Journal of Dentistry
Svante Twetman, Vineet Dhar
PURPOSE: The purpose of this paper was to systematically review the quality of evidence related to self-applied and professionally applied fluorides, antimicrobial agents, fissure sealants, temporary restorations, and restorative care for the prevention and management of early childhood caries (ECC). METHODS: Relevant papers were selected after an electronic search for literature published in English between 2000 and April 2014. From 877 reports, 33 were included for full review...
May 2015: Pediatric Dentistry
Jacky Burns, Kate Hollands
DESIGN: Randomised controlled trial, double blind, in a community setting. INTERVENTION: School children with active caries in primary teeth and no pulpal exposure, fistula or decay in permanent teeth were chosen. Caries and unsupported enamel were left as found and cotton wool rolls were used for isolation. Two drops of NSF or one drop of water were applied to the tooth with a microbrush for two minutes, once in a 12-month period. OUTCOME MEASURE: At one week, five months and 12 months the presence of active caries, as classified using International Caries Detection and Assessment System (ICDAS II) criteria, was measured...
March 2015: Evidence-based Dentistry
H H Hamama, C K Yiu, M F Burrow
BACKGROUND: This study evaluated the antimicrobial effect of a silver diamine fluoride (SDF)/potassium iodide (KI) product (Riva Star) on the viability of intratubular bacteria. METHODS: Forty-five dentine discs prepared from caries-free maxillary premolars were randomly divided into nine groups. Group 1 (negative control) contained non-infected sound dentine discs. The remaining discs were infected with Streptococcus mutans suspension and received dentine treatments as follows: Group 2 (positive control), discs were left untreated; Group 3 SDF/KI (Riva Star); Group 4 chlorhexidine (CHX); Group 5 CHX+SDF/KI; Group 6 Carisolv; Group 7 Carisolv+SDF/KI; Group 8 Papacarie, and Group 9 Papacarie+SDF/KI...
March 2015: Australian Dental Journal
Priscila L L Freire, Thayza C M Stamford, Allan J R Albuquerque, Fabio C Sampaio, Horacinna M M Cavalcante, Rui O Macedo, André Galembeck, Miguel A P Flores, Aronita Rosenblatt
This study aimed to evaluate the cytotoxicity and bactericidal properties of four silver nanoparticle (AgNP) colloids and their ability to inhibit Streptococcus mutans biofilm formation on dental enamel. The cytotoxicity of AgNPs was evaluated based on signs of vascular change on the chorioallantoic membrane using the hen's egg test (HET-CAM). Bactericidal properties and inhibition of S. mutans biofilm formation were determined using a parallel-flow cell system and a dichromatic fluorescent stain. The percentage of viable cells was calculated from regression data generated from a viability standard...
February 2015: International Journal of Antimicrobial Agents
Juliana Mattos-Silveira, Isabela Floriano, Fernanda R Ferreira, Maria E F Viganó, M A Frizzo, Alessandra Reyes, Tatiane F Novaes, Caroline M Moriyama, Daniela P Raggio, José C P Imparato, Fausto M Mendes, Mariana M Braga
BACKGROUND: Approximal surfaces are a challenge to caries lesions control. Silver diamine fluoride (SDF) is a simple,low-cost and promisor intervention for arresting caries lesions, but it has never been tested on approximal surfaces. Our aim is to evaluate the efficacy and cost-efficacy of SDF in arresting initial lesions compared to resin infiltration and exclusively flossing (control group). Our second aim is to assess discomfort and satisfaction regarding interventions. METHODS/DESIGN: This is a randomized clinical trial, double-blinded, placebo-controlled study...
2014: Trials
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