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Caries prevention

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https://www.readbyqxmd.com/read/28346861/biomimetic-remineralization-of-carious-lesions-by-self-assembling-peptide
#1
L Kind, S Stevanovic, S Wuttig, S Wimberger, J Hofer, B Müller, U Pieles
Caries is the most common disease in the world. Great efforts have been undertaken for prevention and to identify a regenerative treatment solution for dental caries. Self-assembling β-sheet forming peptides have previously shown to form 3-dimensional fiber networks supporting tissue regeneration. In particular, the self-assembling peptide P11-4 has shown potential in the treatment and prevention of dental caries. It has previously been shown that application of monomeric P11-4 solution to early carious lesions can increase net mineral gain by forming de novo hydroxyapatite crystals...
March 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28345424/does-a-social-behavioural-gradient-in-dental-health-exist-among-adults-a-cross-sectional-study
#2
Mariantonietta Arrica, Giovanna Carta, Fabio Cocco, Maria Grazia Cagetti, Silvana Sale, Gaetano Ierardo, Laura Strohmenger, Livia Ottolenghi, Guglielmo Campus
Objective To explore the potential presence of a social/behavioural gradient in dental health among Italian adults using a cross-sectional study. Methods Caries indices were recorded among 480 subjects (52.9% men, 47.1% women) who also completed a structured self-administered social and behavioural questionnaire. A social/behavioural gradient was generated as the sum of the worst circumstances recorded on the questionnaire (cariogenic diet, smoking, lowest occupational profile, brushing teeth < twice daily, lowest educational level, uneven dental examination attendance)...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28344574/health-associated-niche-inhabitants-as-oral-probiotics-the-case-of-streptococcus-dentisani
#3
Arantxa López-López, Anny Camelo-Castillo, María D Ferrer, Áurea Simon-Soro, Alex Mira
Oral diseases, including dental caries and periodontitis, are among the most prevalent diseases worldwide and develop as a consequence of a microbial dysbiosis. Several bacterial strains are being tested as potential oral health-promoting organisms, but usually they are species isolated from niches other than the site where they must exert its probiotic action, typically from fecal samples. We hypothesize that oral inhabitants associated to health conditions will be more effective than traditional, gut-associated probiotic species in key aspects such as colonization of the oral site where disease takes place or the possession of oral health promoting functions, as well as more practical issues like safety and toxicity, and establishing proper doses for administration...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28340098/effect-of-fluoride-releasing-resin-composite-in-white-spot-lesions-prevention-a-single-centre-split-mouth-randomized-controlled-trial
#4
Mohannad M Alabdullah, Alaa Nabawia, Mowaffak A Ajaj, Humam Saltaji
Introduction: The objective of this two-arm split-mouth randomized trial, was to evaluate the ability of fluoride-releasing resin composite to prevent demineralization and white spot lesion (WSL) formation, during orthodontic treatment with fixed appliances. Methods: Patients needing comprehensive orthodontic treatment were randomly allocated into two groups, according to the half split-mouth technique. This trial examined a total of 300 teeth in each group: the control group, in which brackets were fixed with a non-fluoride-containing adhesive resin; and the intervention group, in which brackets were fixed with a fluoride-containing adhesive resin...
March 2, 2017: European Journal of Orthodontics
https://www.readbyqxmd.com/read/28338040/regular-supervised-fluoride-mouthrinse-use-by-children-and-adolescents-associated-with-caries-reduction
#5
Mishel Shahid
Data sourcesCochrane Oral Health Group's Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase, CINAHL, LILACS, BBO, Proquest Dissertations and Theses, Web of Science Conference Proceedings, ClinicalTrials.gov and the WHO International Clinical Trials Registry Platform.Study selectionRandomised or quasi-randomised controlled trials where blind outcome assessment was stated or indicated, comparing fluoride mouthrinse with placebo or no treatment in children up to 16 years of age with a duration of at least 12 months...
March 2017: Evidence-based Dentistry
https://www.readbyqxmd.com/read/28338038/school-based-dental-sealant-programmes-may-be-effective-in-caries-prevention
#6
Tarek Himida, Ucheka Promise
DesignSplit-mouth randomised controlled clinical trial.InterventionSchool-based dental sealant (SBDS) programme. The study population that was selected from 67-year-old pupils of 16 elementary schools in areas of low socioeconomic status within Nice, France. Children with first permanent molar pairs sufficiently erupted for sealing with no caries (ICDAS [International Caries Detection and Assessment System] 0) or initial enamel lesions (ICDAS 1-2) were included. Children were randomised to either the intervention group (light polymerised resin-based sealant with fluoride) or the control group (no treatment)...
March 2017: Evidence-based Dentistry
https://www.readbyqxmd.com/read/28327266/milk-sweetened-with-xylitol-a-proof-of-principle-caries-prevention-randomized-clinical-trial
#7
Donald L Chi, Graciela Zegarra, Elsa C Vasquez Huerta, Jorge L Castillo, Peter Milgrom, Marilyn C Roberts, Ailin R Cabrera-Matta, Ana P Merino
PURPOSE: To evaluate the efficacy of xylitol-sweetened milk as a caries-preventive strategy. METHODS: In this nine-month prospective proof-of-principle trial, Peruvian schoolchildren were randomized to one of five different milk groups: (1) eight g of xylitol per 200 mL milk once per day; (2) four g of xylitol per 100 mL milk twice per day; (3) eight g of sorbitol per 200 mL milk once per day; (4) four g of sorbitol per 100 mL milk twice per day; or (5) eight g of sucrose per 200 mL milk once per day...
September 15, 2016: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/28327260/vitamin-d-and-dental-caries-in-primary-dentition
#8
Ana Lucia Seminario, Elizabet Velan
Traditionally classified as a vitamin, vitamin D represents a group of fat-soluble secosteroids with D2 (ergocalciferol) and D3 (cholecalciferol) being the most relevant of the group. The importance of this prohormone exceeds its known ability to maintain intra- and extracellular calcium and phosphate concentrations, thereby preserving essential metabolic functions such as the promotion of mineralization and maintenance and remodeling of the bone. Current observational research recognizes the potential antiproliferative, prodifferentiative, and immunomodulatory effects of vitamin D and its metabolites in the human body...
September 15, 2016: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/28327259/prevalence-of-enamel-developmental-defects-and-relationship-with-early-childhood-caries-in-trinidad
#9
Rahul S Naidu, June H Nunn
PURPOSE: The purpose of this study was to describe the prevalence of developmental defects of enamel (DDE) and their relationship with early childhood caries (ECC) among preschool children in Trinidad. METHODS: A cross-sectional oral health survey of 251 three- to five-year-old preschool children was undertaken in central Trinidad. The decayed, missing, and filled primary teeth (dmft) index and the DDE index were used to measure visible caries experience and enamel developmental defects, respectively...
September 15, 2016: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/28327110/an-assessment-of-the-impacts-of-child-oral-health-in-indonesia-and-associations-with-self-esteem-school-performance-and-perceived-employability
#10
Diah Ayu Maharani, Melissa Adiatman, Anton Rahardjo, Girvan Burnside, Cynthia Pine
BACKGROUND: Previous surveys have indicated that a majority of Indonesian children have poor oral health. However, little detailed information is available on underlying causation and none that examine impacts of oral health on child self-esteem, school performance and perceived employability. The aim of this study was to determine levels of child oral health in primary school children in Indonesia, the prevalence of key causal factors; and, to determine relationships between oral health, self-esteem and school academic performance...
March 21, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28326737/-research-progress-on-a-nanodrug-delivery-system-for-prevention-and-control-of-dental-caries-and-periodontal-diseases
#11
Jiang Yaling, Feng Mingye, Cheng Lei
Dental caries and periodontal diseases are common chronic infectious diseases that cause serious damage to oral health. Bacteria is the primary factor leading to such conditions. As a dental plaque control method, chemotherapeutic agents face serious challenges in dental care because of the specific physiological and anatomical characteristics of the oral cavity. Nanodrug delivery system is a series of new drug delivery systems at nanoscale, and it can target cells, promote sustainedrelease effects, and enhance biodegradation...
February 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28326714/-effect-of-pinus-massoniana-needle-extract-on-root-dentin-demineralization-in-vitro
#12
Tang Chengfang, Ruan Jianping, Zhu Yong, Li Zixia, Zuo Yanping, Xu Hongyan
OBJECTIVE: This study aims to evaluate the effects of Pinus massoniana needle extract (PMNE) on inhibiting demineralization of root dentin. METHODS: Root dentin blocks were randomly divided into distilled deionized water (DDW) group, fluoride sodium (NaF) group, and 4%, 8% and 12% PMNE groups according to the experimental solution used in the process of pH cycling in each group. All specimens in each group experienced pH cycling for 8 d. The dentin mineral density (DMD) of the normal dentin and demineralized dentin and their D-value (ΔDMD) were determined using micro computed tomography...
October 1, 2016: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28326713/-observation-and-analysis-of-microstructure-of-dentin-caries-lesions-through-3d-laser-scanning-microscope
#13
Xu Lixia, Xu Hongmei, Zhu Xiaoying, Sun Limei
OBJECTIVE: Microstructural changes in dentin carious lesions were investigated using a 3D laser scanning microscope, which has a morphological theoretical foundation in the further study of clinical caries disease prevention and treatments. METHODS: Six fresh extracted caries molars were prepared into cross-section specimens. The sections were examined by 3D and laser measuring morphology. RESULTS: Zones were identified in the lesions on the basis of their optical appearance...
October 1, 2016: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28322360/the-effect-of-casein-phosphopeptide-amorphous-calcium-phosphate-on-molar-incisor-hypomineralisation-%C3%A2-a-pilot-study
#14
Meltem Bakkal, Zerrin Abbasoglu, Betul Kargul
PURPOSE: To evaluate the effect of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and casein phosphopeptide-amorphous calcium fluoride phosphate (CPP-ACFP) application on noncarious MIH (molar-incisor hypomineralisation) lesions by using a DIAGNOdent device (KaVo), which measures laser fluorescence within the mineral structure of the tooth. MATERIALS AND METHODS: A total of 461 subjects age 7-12 (mean ± SD was 9.9 ± 1.6) years were examined. Fifty four children were diagnosed with MIH and divided into 2 groups...
March 20, 2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28322358/inhibitory-effects-of-nitrite-on-acid-%C3%A2-production-in-dental-plaque-in-children
#15
Yuji Yamamoto, Jumpei Washio, Koichi Shimizu, Koei Igarashi, Nobuhiro Takahashi
PURPOSE: To assess the inhibitory effects of nitrite on plaque acidogenicity and its relationship with caries experience. MATERIALS AND METHODS: Plaque (2 μl) was collected from 76 children (age 5.8 = 2.6 years, dmft = 2.9 = 3.5, DMTF = 0.6 = 1.4) and mixed with nitrite solution (final concentration = 0.63 mM) or distilled water (control). The initial pH (pH-0) of each sample was measured using a portable pH meter. The samples were incubated for 10 min, then their pH (pH-1) was measured again...
March 20, 2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28314823/body-size-indicators-and-risk-of-gallbladder-cancer-pooled-analysis-of-individual-level-data-from-19-prospective-cohort-studies
#16
Peter T Campbell, Christina C Newton, Cari M Kitahara, Alpa V Patel, Patricia Hartge, Jill Koshiol, Katherine A McGlynn, Hans-Olov Adami, Amy Berrington de González, Laura E Beane Freeman, Leslie Bernstein, Julie E Buring, Neal D Freedman, Yu-Tang Gao, Graham G Giles, Marc J Gunter, Mazda Jenab, Linda M Liao, Roger L Milne, Kim Robien, Dale P Sandler, Catherine Schairer, Howard D Sesso, Xiao-Ou Shu, Elisabete Weiderpass, Alicja Wolk, Yong-Bing Xiang, Anne Zeleniuch-Jacquotte, Wei Zheng, Susan M Gapstur
Background: There are few established risk factors for gallbladder cancer beyond gallstones. Recent studies suggest a higher risk with high body mass index (BMI), an indicator of general heaviness, but evidence from other body size measures is lacking.Methods: Associations of adult BMI, young adult BMI, height, adult weight gain, waist circumference (WC), waist-height ratio (WHtR), hip circumference (HC), and waist-hip ratio (WHR) with gallbladder cancer risk were evaluated. Individual-level data from 1,878,801 participants in 19 prospective cohort studies (14 studies had circumference measures) were harmonized and included in this analysis...
March 17, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28314382/erratum-to-a-randomized-double-blind-placebo-controlled-clinical-trial-of-fluoride-varnish-in-preventing-dental-caries-of-sj%C3%A3-gren-s-syndrome-patients
#17
Weini Xin, Katherine Chiu Man Leung, Edward Chin Man Lo, Mo Yin Mok, Moon Ho Leung
No abstract text is available yet for this article.
March 17, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28303470/the-caries-preventive-effect-of-1-year-use-of-low-dose-xylitol-chewing-gum-a-randomized-placebo-controlled-clinical-trial-in-high-caries-risk-adults
#18
Fabio Cocco, Giovanna Carta, Maria Grazia Cagetti, Laura Strohmenger, Peter Lingström, Guglielmo Campus
OBJECTIVES: The caries preventive effect of long-term use (1 year) of low-dosage (2.5 g/die) of xylitol chewing gum in a high-caries-risk adult population was evaluated. MATERIALS AND METHODS: In this randomized clinical trial, 179 high-caries-risk adults were assigned to two experimental groups, xylitol and polyols. Caries status, salivary mutans streptococci (MS), and plaque pH were re-evaluated after 2 years from baseline in 66 xylitol and 64 polyol subjects...
March 16, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28291962/matching-the-statistical-model-to-the-research-question-for-dental-caries-indices-with-many-zero-counts
#19
John S Preisser, D Leann Long, John W Stamm
Marginalized zero-inflated count regression models have recently been introduced for the statistical analysis of dental caries indices and other zero-inflated count data as alternatives to traditional zero-inflated and hurdle models. Unlike the standard approaches, the marginalized models directly estimate overall exposure or treatment effects by relating covariates to the marginal mean count. This article discusses model interpretation and model class choice according to the research question being addressed in caries research...
March 15, 2017: Caries Research
https://www.readbyqxmd.com/read/28289474/the-history-of-public-health-use-of-fluorides-in-caries-prevention
#20
Tea Šket, Andreja Kukec, Rok Kosem, Barbara Artnik
AIM: The aim of our study was to chronologically analyse various public health measures of fluoride use in caries prevention. METHODS: We systematically searched the PubMed database on the preventive role of fluorides in public health, published from 1984 to 2014. The search process was divided into four steps, where inclusion and exclusion criteria were defined. Qualitative methodology was used for the article analysis. In the research process, the described forms of F use, diversity of the described F agents, and the observed population group were analysed...
June 1, 2017: Zdravstveno Varstvo
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