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https://www.readbyqxmd.com/read/28650477/video-rate-volumetric-ca-2-imaging-across-cortex-using-seeded-iterative-demixing-sid-microscopy
#1
Tobias Nöbauer, Oliver Skocek, Alejandro J Pernía-Andrade, Lukas Weilguny, Francisca Martínez Traub, Maxim I Molodtsov, Alipasha Vaziri
Light-field microscopy (LFM) is a scalable approach for volumetric Ca(2+) imaging with high volumetric acquisition rates (up to 100 Hz). Although the technology has enabled whole-brain Ca(2+) imaging in semi-transparent specimens, tissue scattering has limited its application in the rodent brain. We introduce seeded iterative demixing (SID), a computational source-extraction technique that extends LFM to the mammalian cortex. SID can capture neuronal dynamics in vivo within a volume of 900 × 900 × 260 μm located as deep as 380 μm in the mouse cortex or hippocampus at a 30-Hz volume rate while discriminating signals from neurons as close as 20 μm apart, at a computational cost three orders of magnitude less than that of frame-by-frame image reconstruction...
June 26, 2017: Nature Methods
https://www.readbyqxmd.com/read/28641073/gonorrhoea-testing-and-positivity-in-non-remote-aboriginal-community-controlled-health-services
#2
Mary Ellen Harrod, Sophia Couzos, James Ward, Mark Saunders, Basil Donovan, Belinda Hammond, Dea Delaney-Thiele, Mary Belfrage, Sid Williams, Lucy Watchirs Smith, John M Kaldor
Background: Gonorrhoea occurs at high levels in young Aboriginal and Torres Strait Islander people living in remote communities, but there are limited data on urban and regional settings. An analysis was undertaken of gonorrhoea testing and positivity at four non-remote Aboriginal Community Controlled Health Services participating in a collaborative research network. Methods: This was a retrospective analysis of clinical encounter data derived from electronic medical records at participating services. Data were extracted using the GRHANITE program for all patients aged 15-54 years from 2009 to 2013...
June 22, 2017: Sexual Health
https://www.readbyqxmd.com/read/28638816/prevalence-of-asthma-among-middle-eastern-children-a-systematic-review
#3
REVIEW
Masoud Mirzaei, Mehran Karimi, Shima Beheshti, Masoud Mohammadi
Background: The prevalence of asthma and allergy has increased during the last decades, especially in children. However, little is known about it in the Middle East region. This systematic review is aimed to estimate the prevalence of asthma among the Middle Eastern children. Methods: Local and international scientific databases including SID, Iranmedex, Medline and Science Direct were systematically searched for relevant keywords including; asthma, prevalence, children, International Study of Asthma and Allergies in Childhood (ISACC) and the names of Middle Eastern countries for the period of 1996-2011...
2017: Medical Journal of the Islamic Republic of Iran
https://www.readbyqxmd.com/read/28638811/cost-effectiveness-of-eplerenone-in-treatment-of-cardiovascular-diseases-a-systematic-review
#4
Hossein Mobaraki, Saber Azami-Aghdash, Ali Sarabi Asiabar, Aziz Rezapour, Mohammad Hossein Kafaei Mehr, Saeed Emamgolizadeh
Background: No clear evidence is available on the cost-effectiveness of eplerenone in treatment of cardiovascular diseases. Thus, the present study aimed at systematically reviewing studies that have investigated this issue. Methods: This systematic review study was conducted in 2016. The required information were collected using key Mesh words from the following databases: Google scholar, PubMed, Science Direct, MagIran, SID, Scopus, and handsearching journals and the references of the selected articles. The quality of the selected articles was assessed by the Drummond's checklist...
2017: Medical Journal of the Islamic Republic of Iran
https://www.readbyqxmd.com/read/28631302/l-hcy-induced-cathepsin-v-mediates-the-vascular-endothelial-inflammation-in-hyperhomocysteinemia
#5
Yi-Ping Leng, Ye-Shuo Ma, Xiao-Gang Li, Rui-Fang Chen, Ping-Yu Zeng, Xiao-Hui Li, Cheng-Feng Qiu, Ya-Pei Li, Zhen Zhang, Alex F Chen
BACKGROUND AND PURPOSE: Vascular inflammation, including the expression of inflammatory cytokines in endothelial cells, plays a critical role in hyperhomocysteinemia-associated vascular diseases. Cathepsin V, specifically expressed in humans, is involved in vascular diseases through its elastolytic and collagenolytic activities. The aim of this study was to determine the effects of cathepsin V on the L-homocysteine (L-Hcy)-induced vascular inflammation. EXPERIMENTAL APPROACH: A high methionine diet-induced hyperhomocysteinemic mice model was used to assess the cathepsin V expression and vascular inflammation...
June 20, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28629481/depression-inflammation-and-memory-loss-among-mexican-americans-analysis-of-the-hable-cohort
#6
Leigh A Johnson, Melissa Edwards, Adriana Gamboa, James Hall, Michelle Robinson, Sid E O'Bryant
BACKGROUND: This study explored the combined impact of depression and inflammation on memory functioning among Mexican-American adults and elders. METHODS: Data were analyzed from 381 participants of the Health and Aging Brain study among Latino Elders (HABLE). Fasting serum samples were collected and assayed in duplicate using electrochemiluminesce on the SECTOR Imager 2400A from Meso Scale Discovery. Positive DepE (depression endophenotype) was codified as any score >1 on a five-point scale based on the GDS-30...
June 20, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28617463/robust-wireless-power-transfer-using-a-nonlinear-parity-time-symmetric-circuit
#7
Sid Assawaworrarit, Xiaofang Yu, Shanhui Fan
Considerable progress in wireless power transfer has been made in the realm of non-radiative transfer, which employs magnetic-field coupling in the near field. A combination of circuit resonance and impedance transformation is often used to help to achieve efficient transfer of power over a predetermined distance of about the size of the resonators. The development of non-radiative wireless power transfer has paved the way towards real-world applications such as wireless powering of implantable medical devices and wireless charging of stationary electric vehicles...
June 14, 2017: Nature
https://www.readbyqxmd.com/read/28615326/prenatal-nicotinic-exposure-prolongs-superior-laryngeal-c-fiber-mediated-apnea-and-bradycardia-through-enhancing-neuronal-trpv1-expression-and-excitation
#8
Xiuping Gao, Lei Zhao, Jianguo Zhuang, Na Zang, Fadi Xu
Maternal cigarette smoke, including prenatal nicotinic exposure (PNE), is responsible for sudden infant death syndrome (SIDS). The fatal events of SIDS are characterized by severe bradycardia and life-threatening apneas. Although activation of transient receptor potential vanilloid 1 (TRPV1) of superior laryngeal C-fibers (SLCFs) could induce bradycardia and apnea and has been implicated in SIDS pathogenesis, how PNE affects the SLCF-mediated cardiorespiratory responses remains unexplored. Here, we tested the hypothesis that PNE would aggravate the SLCF-mediated apnea and bradycardia via up-regulating TRPV1 expression and excitation of laryngeal C-neurons in the nodose/jugular (N/J) ganglia...
June 14, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28608686/targeted-metabolic-profiling-of-post-mortem-brain-from-infants-who-died-from-sudden-infant-death-syndrome
#9
Stewart F Graham, Onur Turkoglu, Praveen Kumar, Ali Yilmaz, Trent C Bjorndahl, BeomSoo Han, Rupasri Mandal, David S Wishart, Ray O Bahado-Singh
Currently little is known about the underlying pathophysiology associated with SIDS, and no objective biomarkers exist for the accurate identification of those at greatest risk of dying from SIDS. Using targeted metabolomics, we aim to profile the medulla oblongata of infants who have died from SIDS (n = 16) and directly compare their biochemical profile with age matched controls. Combining data acquired using (1)H NMR and targeted DI-LC-MS/MS, we have identified fatty acid oxidation as a pivotal biochemical pathway perturbed in the brains of those infants who have from SIDS (p = 0...
June 20, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28602839/epidemiology-of-brucellosis-in-iran-a-comprehensive-systematic-review-and-meta-analysis-study
#10
REVIEW
Reza Mirnejad, Faramarz Masjedian Jazi, Shayan Mostafaei, Mansour Sedighi
Brucellosis is still one of the most challenging issues for health and the economy in many developing countries such as Iran. Considering the high prevalence of brucellosis, the aim of the current study was to systematically review published data about the annual incidence rate of this infection from different parts of Iran and provide an overall relative frequency (RF) for Iran using meta-analysis. We searched several databases including PubMed, ISI Web of Science, Scopus, google scholar, IranMedex and Iranian Scientific Information Database (SID) by using the following keywords: "Brucella", "Brucellosis", "Malta fever", "Mediterranean fever", "undulant fever", "zoonosis" and "Iran" in Title/Abstract/Keywords fields...
June 7, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28593563/spatio-temporal-monitoring-of-cotton-cultivation-using-ground-based-and-airborne-multispectral-sensors-in-gis-environment
#11
Antonis Papadopoulos, Dionissios Kalivas, Sid Theocharopoulos
Multispectral sensor capability of capturing reflectance data at several spectral channels, together with the inherent reflectance responses of various soils and especially plant surfaces, has gained major interest in crop production. In present study, two multispectral sensing systems, a ground-based and an aerial-based, were applied for the multispatial and temporal monitoring of two cotton fields in central Greece. The ground-based system was Crop Circle ACS-430, while the aerial consisted of a consumer-level quadcopter (Phantom 2) and a modified Hero3+ Black digital camera...
July 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28593499/in-utero-exposure-to-nicotine-alters-the-development-of-the-rabbit-cardiac-conduction-system-and-provides-a-potential-mechanism-for-sudden-infant-death-syndrome
#12
Anh Tuan Ton, Michael Biet, Jean-Francois Delabre, Nathalie Morin, Robert Dumaine
In-utero exposure to tobacco smoke remains the highest risk factor for sudden infant death syndrome (SIDS). To alleviate the risks, nicotine replacement therapies are often prescribed to women who wish to quit smoking during their pregnancy. Cardiac arrhythmias is considered the final outcome leading to sudden death. Our goal in this study was to determine if exposing rabbit fetus to nicotine altered the cardiac conduction system of newborn kittens in a manner susceptible to cause SIDS. Using neuronal markers and a series of immunohistological and electrophysiological techniques we found that nicotine delayed the development of the cardiac pacemaker center (sinoatrial node) and decreased its innervation...
June 7, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/28589871/prevalence-of-cystic-echinococcosis-in-iran-a-systematic-review-and-meta-analysis
#13
H R Khalkhali, M Foroutan, S Khademvatan, H Majidiani, S Aryamand, P Khezri, A Aminpour
As a significant zoonosis, cystic echinococcosis (CE) is endemic in some parts of the world, such as the Middle East. There are studies on the prevalence of this infection in animal and human reservoirs in Iran; hence, we conducted this meta-analysis to elucidate the prevalence of CE in Iran. English (PubMed, Scopus, Web of Science, Science Direct and Google Scholar) and Persian (Magiran, Iran Medex, Iran Doc and SID) databases were explored. In the case of definitive, animal and human intermediate hosts, 37, 90 and 33 studies, respectively, have been included in the current review from January 1990 to December 2015...
June 7, 2017: Journal of Helminthology
https://www.readbyqxmd.com/read/28580444/maternal-anemia-during-pregnancy-and-infant-low-birth-weight-a-systematic-review-and-meta-analysis
#14
REVIEW
Shoboo Rahmati, Ali Delpishe, Milad Azami, Mohammed Reza Hafezi Ahmadi, Kurosh Sayehmiri
BACKGROUND: Infant low birth weight is one of the major problems in different societies. Different reports have provided different results regarding the relationship between maternal anemia and infant low birth weight in different months of pregnancy. OBJECTIVE: The aim of this study was to determine the relationship between maternal anemia during pregnancy and infant low birth weight. MATERIALS AND METHODS: This systematic review was conducted using related keywords in national (Sid, Iran...
March 2017: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/28573795/digestible-indispensable-amino-acid-score-diaas-and-protein-digestibility-corrected-amino-acid-score-pdcaas-in-oat-protein-concentrate-measured-in-20-to-30-kilogram-pigs
#15
Jerubella J Abelilla, Yanhong Liu, Hans H Stein
BACKGROUND: Oat protein concentrate is often used in human food, but the quality of this protein has not been characterized. Therefore, the objectives of this experiment were to determine the standardized ileal digestibility (SID) of crude protein (CP) and amino acids (AA) in oat protein concentrate and to determine differences in protein quality estimates between the protein digestibility-corrected AA score (PDCAAS) and the digestible indispensable AA score (DIAAS) when using growing pigs for both measurements...
June 2, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28572950/relative-validation-of-a-short-questionnaire-to-assess-the-dietary-habits-of-pregnant-american-indian-women
#16
Terryl J Hartman, Amy J Elliott, Jyoti Angal, Torin Block, Erin P Ferranti, Diane C Mitchell, Dana C Nickleach, Jean C Norris, Rosalind A Breslow
The objective of this study was to compare a short dietary screener developed to assess diet quality with interviewer-administered telephone 24-hour dietary recalls in a population of pregnant Northern Plains (NP) American Indian women. Participants were recruited from NP clinical sites of the Prenatal Alcohol and SIDS and Stillbirth (PASS) Network, as part of a large, prospective, multidisciplinary study. Prenatal PASS participants who enrolled prior to 24 weeks gestation were eligible to participate. Repeated 24-hour dietary recalls were collected using the Nutrition Data System for Research (NDSR) software and a short dietary screener was administered intended to capture usual dietary intake during pregnancy...
May 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28562296/race-ethnicity-and-sids
#17
Richard D Goldstein, Hannah C Kinney
No abstract text is available yet for this article.
May 15, 2017: Pediatrics
https://www.readbyqxmd.com/read/28555503/spontaneous-isolated-dissection-and-atherosclerotic-plaques-of-superior-mesenteric-artery-the-vastly-different-occurrence-site-suggests-the-opposite-haemodynamic-aetiology
#18
Zhi-Gang Min, Hai-Rong Shan, Long Xu, Su Yan, Xue-Xia Sheng, Jian Ji, Zhi-Hong Cao
OBJECTIVE: The development of atherosclerotic plaques and spontaneous isolated dissection (SID) of the superior mesenteric artery (SMA) was considered to be related to opposite haemodynamics. The purpose of this study was to compare their occurrence sites and the morphology of the SMA to confirm the haemodynamic aetiologies. METHODS: 57 patients with SID and 64 patients with atherosclerotic plaques were compared about patient characteristics, location of SID and plaque, the distance from lesion to the aortic ostia, SMA branching angle and inlet diameter of the SMA...
June 23, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28549309/switching-between-intravenous-and-subcutaneous-trastuzumab-safety-results-from-the-prefher-trial
#19
Joseph Gligorov, Giuseppe Curigliano, Volkmar Müller, Ann Knoop, Valerie Jenkins, Sunil Verma, Stuart Osborne, Sabine Lauer, Zuzana Machackova, Lesley Fallowfield, Xavier Pivot
AIM: To assess the safety and tolerability of switching between subcutaneous (SC) and intravenous (IV) trastuzumab in the PrefHer study (NCT01401166). PATIENTS AND METHODS: Patients with HER2-positive early breast cancer completed (neo)adjuvant chemotherapy and were randomised to receive four cycles of SC trastuzumab, via single-use injection device (SID; Cohort 1) or hand-held syringe (Cohort 2), followed by four cycles of IV, or vice versa (the crossover period presented here) as part of their 18 standard cycles of adjuvant trastuzumab treatment...
May 23, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28546938/prevalence-of-diabetic-retinopathy-in-iran-a-systematic-review-and-meta-analysis
#20
Saman Maroufizadeh, Amir Almasi-Hashiani, Mostafa Hosseini, Mahdi Sepidarkish, Reza Omani Samani
AIM: To estimate the overall prevalence of diabetic retinopathy (DR) in Iran by a systematic review and Meta-analysis. METHODS: We conducted a search of all published literature on diabetic patients for the prevalence of DR using Web of Sciences, PubMed, Scopus, Google Scholar, and national electronic databases SID, Magiran, and Iranmedex from their inception until September 2016 with standard keywords. Pooled estimates of the DR prevalence and the corresponding 95% confidence intervals (CI) were calculated using random effects models...
2017: International Journal of Ophthalmology
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