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https://www.readbyqxmd.com/read/28328658/a-systematic-review-on-the-epidemiology-of-pediatric-burn-in-iran
#1
Sayed Saeed Hashemi, Asaad Sharhani, Bahare Lotfi, Toraj Ahmadi-Juibari, Zahra Shaahmadi, Abbas Aghaei
Burn is the most common pediatric injuries all over the world. The aim of this study was to study the epidemiology of burn in under 15-year-old Iranian children by applying a systematic review. The related articles published before 2016 have been gathered from international databases by using the keywords in term of pediatric burns such as ScienceDirect, PubMed, Iranmedex, Google Scholar, Embase, Magiran, and SID. The checklists of STROBE have been applied to evaluate the quality of the reviewed data. A total of 35 relevant studies were extracted and evaluated...
March 15, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28327050/infant-bed-sharing-supporting-parents-to-make-an-informed-decision
#2
Layla Lavallee, Meredith Scannell
The practice of infant bed-sharing remains controversial in countries such as the UK and the US, despite its prevalence, and healthcare professionals are often faced with the task of advising parents on bed-sharing without the support of consistent or up-to-date guidelines. This article explores UK and US recommendations on infant bed-sharing, considering the existing evidence. The possible relationship between infant bed-sharing and sudden infant death syndrome (SIDS) is explored, alongside other factors that may be linked to SIDS...
March 22, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28326963/the-stillbirth-classification-system-for-the-safe-passage-study
#3
Theonia K Boyd, Colleen A Wright, Hein J Odendaal, Amy J Elliott, Mary Ann Sens, Rebecca D Folkerth, Drucilla J Roberts, Hannah C Kinney
Objective Describe the classification system for assigning the cause of stillbirth in the Safe Passage Study, an international, multi-institutional, prospective analysis conducted by the NIAAA/NICHD-funded Prenatal Alcohol in SIDS and Stillbirth (PASS) Research Network. The study mission is to determine the role of prenatal alcohol and/or cigarette smoke exposure in adverse pregnancy outcomes, including stillbirth, in a high-risk cohort of 12,000 maternal/fetal dyads. Methods The PASS Network classification system is based upon 5 "sites of origin" for cause of stillbirth, further subdivided into mechanism subcategories; both are employed to assign an ultimate cause of death...
March 2017: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/28318119/rural-hospital-employment-of-physicians-and-use-of-cesareans-and-nonindicated-labor-induction
#4
Shailendra Prasad, Peiyin Hung, Carrie Henning-Smith, Michelle Casey, Katy Kozhimannil
OBJECTIVE: Workforce issues constrain obstetric care services in rural US hospitals, and one strategy hospitals use is to employ physicians to provide obstetric care. However, little is known about the relationship between hospital employment of maternity care physicians and use of obstetric care procedures in rural hospitals. We examined the association between obstetric physician employment and use of cesareans and nonindicated labor induction. STUDY DESIGN: We conducted a cross-sectional analysis of a telephone survey of all 306 rural hospitals providing obstetric care in 9 states from November 2013 to March 2014 and linked the survey data (N = 263, 86% response rate) to all-payer childbirth data on maternity care utilization from 2013 Statewide Inpatient Database (SID) hospital discharge data...
March 20, 2017: Journal of Rural Health
https://www.readbyqxmd.com/read/28316956/sudden-infant-death-syndrome-due-to-long-qt-syndrome-a-brief-review-of-the-genetic-substrate-and-prevalence
#5
REVIEW
Nikolaos S Ioakeimidis, Theodora Papamitsou, Soultana Meditskou, Zafiroula Iakovidou-Kritsi
The pathophysiological mechanisms which lead to sudden infant death syndrome (SIDS) are not completely understood. Cardiac channelopathies are a well-established causative factor with long QT syndrome (LQTS) being the most frequent one, accounting for approximately 12% of SIDS cases. The genetic substrate of the above arrhythmogenic syndrome has been thoroughly described but only specific gene mutations or polymorphisms have been identified as SIDS causative. The review will focus on the prevalence of LQTS-induced SIDS or near-SIDS cases and the mutations held responsible...
December 2017: Journal of Biological Research
https://www.readbyqxmd.com/read/28301981/alterations-of-hepatocyte-function-with-free-radical-generators-and-reparation-or-prevention-with-coffee-polyphenols
#6
Amel Saidi Merzouk, Merzouk Hafida, Amel Medjdoub, Bouchra Loukidi, Sabri Cherrak, Sid Ahmed Merzouk, Mourad Elhabiri
Liver diseases are linked in the majority of cases to oxidative stress that antioxidants could neutralize with reducing liver injury. Chlorogenic acid, a coffee polyphenol, possesses antioxidant prosperities. The aim of this study was to evaluate in vitro preventive and corrective effects of cholorogenic acid in hepatocyte toxicity induced by free radicals. Hepatocytes were isolated from adult male Wistar rats. To determine corrective effects and reparation, cells were first exposed to two free radical generators (Hydrogen peroxide/Iron sulfate for hydroxyl radical formation, and Phenazine methosulfate/Nicotinamide adenine dinucleotide for superoxide anion formation) for 12H and thereafter treated by chlorogenic acid (1 and 10 µM final concentration) for another 12H...
March 16, 2017: Free Radical Research
https://www.readbyqxmd.com/read/28300869/e-selectin-inhibition-with-gmi-1271-decreases-venous-thrombosis-without-profoundly-affecting-tail-vein-bleeding-in-a-mouse-model
#7
Dorian L Culmer, Misha L Dunbar, Angela E Hawley, Suman Sood, Robert E Sigler, Peter K Henke, Thomas W Wakefield, John L Magnani, Daniel D Myers
Selectins, such as E-selectin (CD62E), function in venous thrombosis by binding and activating immune cells to initiate the coagulation cascade. GMI-1271 is a small molecule antagonist that inhibits E-selectin activity. Here we determine whether inhibition of E-selectin is sufficient to decrease acute venous thrombosis and associated inflammatory events in both prophylactic and treatment protocols without significantly affecting haemostasis. Male C57BL/6 mice underwent surgery for experimental thrombosis induction and were harvested at peak thrombus formation in our animal model, two days post induction...
March 16, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/28295538/authorised-access-web-portal-for-italiandata-bank-on-sudden-unexpected-perinatal-and-infant-death
#8
Giulia Ottaviani, Paolo Perlasca, Marco Mesiti, Luca Ferrari, Anna M Lavezzi
Sudden infant death syndrome (SIDS) is common during the first year of life and affects 0.40every 1,000 births (1). Stillbirths are seven times more common than SIDS; in 40-80% of cases remain unexplained and are categorised as sudden intrauterine unexpected death syndrome (2).In 2006 Italy passed legislation that fetuses, and infants, from 25 weeks of gestation to one postnatal year, that died suddenly and unexpectedly should be sent to the University of Milan, Italy, for an in-depth diagnostic post-mortem with parental permission (3)...
March 15, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28291919/an-in-house-protocol-for-improved-flood-field-calibration-of-truebeam-fff-cine-imaging
#9
Austin M Faught, Fang-Fang Yin, Justus Adamson
PURPOSE: TrueBeams equipped with the 40 × 30 cm(2) Electronic Portal Imaging Devices (EPIDs) are prone to image saturation at the image center when used with flattening filter free (FFF) photon energies. While cine imaging during treatment may not saturate because the beam is attenuated by the patient, the flood field calibration is affected when the standard calibration procedure is followed. Here, we describe the hardware and protocol to achieve improved image quality for this model of TrueBeam EPID...
January 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28290334/gonad-dose-in-ap-pelvis-radiography-impact-of-anode-heel-orientation
#10
H A A B Mraity, A England, P Hogg
PURPOSE: For antero posterior (AP) pelvis radiographic examination, determine the impact of anode heel orientation on female/male gonad dose. METHODS: High sensitivity thermo-luminescent dosimeters (TLDs) were used with an ATOM dosimetry phantom; the phantom was positioned for AP pelvis. TLDs were placed into the testes and ovaries. Radiation dose received by these organs was measured with the feet toward anode and feet toward the cathode. kVp, mAs and SID were manipulated to generate a range of exposures...
February 2017: Radiography
https://www.readbyqxmd.com/read/28279500/how-often-is-congenital-heart-disease-recognized-as-a-significant-comorbidity-among-hospitalized-adults-with-congenital-heart-disease
#11
James M Robbins, Jennifer Onukwube, Anthony Goudie, R Thomas Collins
BACKGROUND: Despite frequent life-long hemodynamic and electrophysiologic abnormalities, adults with congenital heart defects (CHDs) are often lost to medical follow-up. Using a cohort of adults with CHD receiving hospital care in Arkansas, we sought to determine how often a CHD is recognized and coded during hospital admissions. METHODS: Data for this study come from the Agency for Healthcare Research and Quality's Arkansas State Inpatient Database (SID) for years 2004 to 2012...
February 22, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28279012/unsuppressible-repetition-suppression-and-exemplar-specific-expectation-suppression-in-the-fusiform-face-area
#12
Auréliane Pajani, Sid Kouider, Paul Roux, Vincent de Gardelle
Recent work casts Repetition Suppression (RS), i.e. the reduced neural response to repeated stimuli, as the consequence of reduced surprise for repeated inputs. This research, along with other studies documenting Expectation Suppression, i.e. reduced responses to expected stimuli, emphasizes the role of expectations and predictive codes in perception. Here, we use fMRI to further characterize the nature of predictive signals in the human brain. Prior to scanning, participants were implicitly exposed to associations within face pairs...
December 2017: Scientific Reports
https://www.readbyqxmd.com/read/28277980/sidt2-mediates-gymnosis-the-uptake-of-naked-single-stranded-oligonucleotides-into-living-cells
#13
Masayuki Takahashi, Viorica Raluca Contu, Chihana Kabuta, Katsunori Hase, Yuuki Fujiwara, Keiji Wada, Tomohiro Kabuta
Single-stranded oligonucleotides (ssOligos) are efficiently taken up by living cells without the use of transfection reagents. This phenomenon called 'gymnosis' enables the sequence-specific silencing of target genes in various types of cells. Several antisense ssOligos are used for the treatment of human diseases. However, the molecular mechanism underlying the uptake of naked ssOligos into cells remains to be elucidated. Here, we show that systemic RNA interference deficient-1 (SID-1) transmembrane family 2 (SIDT2), a mammalian ortholog of the Caenorhabditis elegans double-stranded RNA channel SID-1, mediates gymnosis...
March 9, 2017: RNA Biology
https://www.readbyqxmd.com/read/28270640/prevalence-of-depression-in-hemodialysis-patients-in-iran-a-systematic-review-and-meta-analysis
#14
Hamid Ravaghi, Masoud Behzadifar, Meysam Behzadifar, Masood Taheri Mirghaed, Aidin Aryankhesal, Morteza Salemi, Nicola Luigi Bragazzi
INTRODUCTION: Chronic kidney disease is a public health problem worldwide that is highly associated with psychological disorders. This study aimed to assess prevalence of depression in hemodialysis patients in Iran. MATERIALS AND METHODS: Relevant studies were identified from the PubMed, ISI Web of Science, Ovid, Scopus, EMBase, and Iranian databases including Magiran, SID, IranMedex, and Irandoc, up to December 2015. The DerSimonian-Laird random effects model was employed to estimate the overall pooled prevalence...
March 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/28259087/medical-marijuana-policies-and-hospitalizations-related-to-marijuana-and-opioid-pain-reliever
#15
Yuyan Shi
OBJECTIVES: Twenty-eight states in the U.S have legalized medical marijuana, yet its impacts on severe health consequences such as hospitalizations remain unknown. Meanwhile, the prevalence of opioid pain reliever (OPR) use and outcomes has increased dramatically. Recent studies suggested unintended impacts of legalizing medical marijuana on OPR, but the evidence is still limited. This study examined the associations between state medical marijuana policies and hospitalizations related to marijuana and OPR...
February 21, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28255991/factors-associated-with-early-readmission-among-patients-discharged-to-post-acute-care-facilities
#16
Carolyn Horney, Roberta Capp, Rebecca Boxer, Robert E Burke
BACKGROUND: Over a quarter of Medicare patients admitted to the hospital are discharged to post-acute care (PAC) facilities, but face high rates of readmission. Timing of readmission may be an important factor in identifying both risk for and preventability of future readmissions. This study aims to define factors associated with readmission within the first week of discharge to PAC facilities following hospitalization. DESIGN AND MEASUREMENTS: This was a secondary analysis of the 2011 Healthcare Cost and Utilization Project (HCUP) State Inpatient Databases (SID) for California, Massachusetts, and Florida...
March 3, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28245091/syn-004-ribaxamase-an-oral-beta-lactamase-mitigates-antibiotic-mediated-dysbiosis-in-a-porcine-gut-microbiome-model
#17
Sheila Connelly, J Andrew Bristol, Steven Hubert, Poorani Subramanian, Nur A Hasan, Rita R Colwell, Michael Kaleko
AIM: To evaluate an antibiotic-inactivation strategy to protect the gut microbiome from antibiotic-mediated damage. METHODS AND RESULTS: SYN-004 (ribaxamase) is an orally-delivered beta-lactamase intended to degrade penicillins and cephalosporins within the gastrointestinal tract to protect the microbiome. Pigs (20 kg, n=10) were treated with ceftriaxone (IV, 50 mg kg(-1) , SID) for 7 days and a cohort (n=5) received ribaxamase (PO, 75 mg, QID) for 9 days beginning the day before antibiotic administration...
February 28, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28243658/surface-induced-dissociation-as-a-tool-to-study-membrane-protein-complexes
#18
Sophie R Harvey, Yang Liu, Wen Liu, Vicki H Wysocki, Arthur Laganowsky
Native ion mobility mass spectrometry (MS) and surface induced dissociation (SID) are applied to study the integral membrane protein complexes AmtB and AqpZ. Fragments produced from SID are consistent with the solved structures of these complexes. SID is, therefore, a promising tool for characterization of membrane protein complexes.
March 9, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28243306/canal-configuration-of-mesiobuccal-roots-in-permanent-maxillary-first-molars-in-iranian-population-a-systematic-review
#19
Mandana Naseri, Mohammad Javad Kharazifard, Sepanta Hosseinpour
OBJECTIVES: It is essential for clinicians to have adequate knowledge about root canal configurations; although its morphology varies largely in different ethnicities and even in different individuals with the same ethnic background. The current study aims to review the root canal configurations of mesiobuccal roots of maxillary first molars in an Iranian population based on different epidemiological studies. MATERIALS AND METHODS: A comprehensive search was conducted to retrieve articles related to root canal configuration and prevalence of each type of root canal based on Vertucci's classification for the mesiobuccal root of maxillary first molars...
November 2016: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/28236403/phytochemistry-pharmacology-and-therapeutic-uses-of-black-seed-nigella-sativa
#20
REVIEW
Wesam Kooti, Zahra Hasanzadeh-Noohi, Naim Sharafi-Ahvazi, Majid Asadi-Samani, Damoon Ashtary-Larky
Black seed (Nigella sativa) is an annual flowering plant from Ranunculaceae family, native to southwest Asia. This plant has many food and medicinal uses. The use of its seeds and oil is common for treatment of many diseases, including rheumatoid arthritis, asthma, inflammatory diseases, diabetes and digestive diseases. The purpose of this study was to provide a comprehensive review on the scientific reports that have been published about N. sativa. The facts and statistics presented in this review article were gathered from the journals accessible in creditable databases such as Science Direct, Medline, PubMed, Scopus, EBSCO, EMBASE, SID and IranMedex...
October 2016: Chinese Journal of Natural Medicines
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