Read by QxMD icon Read


Lu Xu, Gordon Bosiljevac, Kyle Yu, Yi Y Zuo
Langmuir monolayer self-assembled at the air-water interface represents an excellent model for studying phase transition and lipid polymorphism in two dimensions. Compared to numerous studies of phospholipid phase transitions induced by isothermal compression, there are very scarce reports on two-dimensional phase transitions induced by isobaric heating. This is mainly due to technical difficulties of continuously regulating temperature variations while maintaining a constant surface pressure in a classical Langmuir-type film balance...
March 22, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
Ruirui Li, Pengfei Gu, Xiangyu Fan, Junyu Shen, Yulian Wu, Lixuan Huang, Qiang Li
A polyhydroxyalkanoate (PHA)-producing strain was isolated from propylene oxide (PO) saponification wastewater activated sludge and was identified as Brevundimonas vesicularis UJN1 through 16S rDNA sequencing and Biolog microbiological identification. Single-factor and response surface methodology experiments were used to optimize the culture medium and conditions. The optimal C/N ratio was 100/1.04, and the optimal carbon and nitrogen sources were sucrose (10 g/L) and NH4 Cl (0.104 g/L) respectively. The optimal culture conditions consisted of initial pH of 6...
March 21, 2018: Applied Biochemistry and Biotechnology
João R Bezerra-Neto, Natalia G Sousa, Luis P M Dos Santos, Adriana N Correia, Pedro de Lima-Neto
The effect of water on the physicochemical properties of an ethylene glycol and choline chloride mixture containing Cu2+ ions was investigated by electrochemical techniques and molecular dynamics simulation. The experiments and computational calculations were carried out by increasing the water content from 0 up to 10% (v/v). The cyclic voltammetry and chronopotentiometry techniques showed that the diffusion coefficient of Cu2+ ions increased and that the peak potentials for both the Cu2+/Cu+ and Cu+/Cu redox couples shifted towards more positive potentials with the increase in the water content in the solution...
March 22, 2018: Physical Chemistry Chemical Physics: PCCP
Edgard M Mejia, Hana Zegallai, Eric D Bouchard, Versha Banerji, Amir Ravandi, Grant M Hatch
The mitochondrial polyglycerophospholipid cardiolipin (CL) is remodeled to obtain specific fatty acyl chains. This is predominantly accomplished by the transacylase enzyme tafazzin (TAZ). Barth Syndrome (BTHS) patients with TAZ gene mutations exhibit impaired TAZ activity and loss in mitochondrial respiratory function. Previous studies identified monolysocardiolipin acyltransferase-1 (MLCL AT-1) as a mitochondrial enzyme capable of remodelling CL with fatty acid. In this study, we analyzed what relationship, if any, exits between TAZ and MLCL AT-1 with regard to CL remodeling and if transfection of BTHS lymphoblasts with a MLCL AT-1 expression construct improves mitochondrial respiratory function...
March 21, 2018: Journal of Biological Chemistry
Tuerdimaimaiti Abudula, Lassaad Gzara, Giovanna Simonetti, Ahmed Alshahrie, Numan Salah, Pierfrancesco Morganti, Angelo Chianese, Afsoon Fallahi, Ali Tamayol, Sidi A Bencherif, Adnan Memic
Chitin and lignin primarily accumulate as bio-waste resulting from byproducts of crustacean crusts and plant biomass. Recently, their use has been proposed for diverse and unique bioengineering applications, amongst others. However, their weak mechanical properties need to be improved in order to facilitate their industrial utilization. In this paper, we fabricated hybrid fibers composed of a chitin-lignin (CL)-based sol-gel mixture and elastomeric poly (glycerol sebacate) (PGS) using a standard electrospinning approach...
March 19, 2018: Materials
Omorogieva Ojo, Osarhumwese Osaretin Ojo, Fajemisin Adebowale, Xiao-Hua Wang
BACKGROUND: The increasing prevalence of diabetes in the United Kingdom and worldwide calls for new approaches to its management, and diets with low glycaemic index have been proposed as a useful means for managing glucose response. However, there are conflicting reports and differences in the results of studies in terms of their effectiveness. Furthermore, the impact of low-glycaemic index diets and their long-term use in patients with type 2 diabetes remains unclear. OBJECTIVES: The objective of this study was to conduct a systematic review and meta-analysis of the effect of low-glycaemic index diets in patients with type 2 diabetes...
March 19, 2018: Nutrients
Seyyed Milad Abrishamifar, Negar Heidari, Razieh Razavi, Milad Janghorban Lariche, Meysam Najafi
The adsorption of H2Se molecule on AlN-NCS and AlP-NCS surfaces were investigated by using of DFT calculations. The potentials of Cl-functionalized AlN-NCS and AlP-NCS for H2Se adsorption were examined. All processes of H2Se-adsorption on considered nanocone sheets were exothermic reactions. The calculated |Ead| amount of complex H2Se with AlP-NCS was higher than AlN-NCS. The functionalization of considered nanocone sheets with Cl atom increase |Ead| amount of H2Se. Results reveal that, obtained Ead amounts of considered nanocone sheets have linear relationships with corresponding orbital energy amounts...
March 2018: Acta Chimica Slovenica
Naouel Eddaikra, Khatima Ait-Oudhia, Ihcen Kherrachi, Bruno Oury, Farida Moulti-Mati, Razika Benikhlef, Zoubir Harrat, Denis Sereno
BACKGROUND: In Algeria, the treatment of visceral and cutaneous leishmanioses (VL and CL) has been and continues to be based on antimony-containing drugs. It is suspected that high drug selective pressure might favor the emergence of chemoresistant parasites. Although treatment failure is frequently reported during antimonial therapy of both CL and VL, antimonial resistance has never been thoroughly investigated in Algeria. Determining the level of antimonial susceptibility, amongst Leishmania transmitted in Algeria, is of great importance for the development of public health policies...
March 21, 2018: PLoS Neglected Tropical Diseases
Peter G Bittar, Anna R Carlson, Ann Mabie-DeRuyter, Jeffrey R Marcus, Alexander C Allori
OBJECTIVE: Our objective is to describe the process of adapting a conceptual framework into a practical toolkit for one cleft team. DESIGN: This is a single-arm implementation study in a single institution. SETTING: Implementation took place at a mid-sized multidisciplinary clinic for patients with cleft lip and/or palate (CL/P) from urban/suburban and rural areas across North Carolina and neighboring states. PARTICIPANTS: Eligible participants were patients with CL/P from English-speaking families...
January 1, 2018: Cleft Palate-craniofacial Journal
Trey S Rottgen, Andrew J Nickerson, Emily A Minor, Amanda B Stewart, Abby D Harold, Vazhaikkurichi M Rajendran
Attenuated Ca2+ -activated Cl- secretion has previously been observed in the model of dextran-sulfate-sodium (DSS)-induced colitis. Prior studies have implicated dysfunctional muscarinic signaling from basolateral membranes as the potential perpetrator leading to decreased Ca2+ -activated Cl- secretion. However, in our chronic model of DSS-colitis, Chrm3 transcript (1.028 {plus minus} 0.12 vs. 1.029 {plus minus} 0.27, p > 0.05) and CHRM3 protein expression (1.021 {plus minus} .24 vs. .928 {plus minus} .09, p > 0...
March 21, 2018: American Journal of Physiology. Cell Physiology
Biwu Liu, Peng Wu, Zhicheng Huang, Lingzi Ma, Juewen Liu
Functionalization of a gold surface with DNA is often complicated by kinetic traps from unintended DNA base adsorption. Herein, we communicate that Br- serves as a robust backfilling agent displacing selected DNA bases on gold. Traditional thiol backfillers are too strong, while even 300 mM Br- is well tolerated. Conjugates prepared with Br- hybridize 10-fold faster and resist DNA release with better colloidal stability yielding highly sensitive probes. From colorimetric and Raman assays, adsorption affinity ranks as F- < T ≈ Cl- < C < G ≈ Br- < A < I- , allowing Br- to displace nonpoly-A sequences from gold...
March 22, 2018: Journal of the American Chemical Society
Marija Nišavić, Goran V Janjić, Amela Hozić, Marijana Petković, Miloš K Milčić, Zoran Vujčić, Mario Cindrić
Binding of three ruthenium(ii) compounds of general formula mer-[Ru(L3)(N-N)X][Y] (where L3 = 4'-chloro-2,2':6',2''-terpyridine (Cl-tpy); N-N = 1,2-diaminoethane (en), 1,2-diaminocyclohexane (dach) or 2,2'-bipyridine (bipy); X = Cl; Y = Cl) to human serum albumin (HSA) has been investigated by nano-LC/nano-ESI MS and docking studies. A bottom-up proteomics approach has been applied for the structural characterization of metallated proteins and the data were analyzed in both the positive and negative ion mode...
March 21, 2018: Metallomics: Integrated Biometal Science
Ming Zheng, Fang-Yuan Chen, Jia-Nan Tian, Qing-Jiang Pan
To provide deep insight into cation-cation interactions (CCIs) involving hexavalent actinyl species that are major components in spent nuclear fuel and pose important implications for the effective removal of radiotoxic pollutants in the environment, a series of homo- and heterobimetallic actinide complexes supported by cyclopentadienyl (Cp) and polypyrrolic macrocycle (H4 L) ligands were systematically investigated using relativistic density functional theory. The metal sort in both parts of (THF)(H2 L)(OAnVI O) and (An')III Cp3 from U to Np to Pu, as well as the substituent bonding to Cp from electron-donating Me to H to electron-withdrawing Cl, SiH3 , and SiMe3 , was changed...
March 21, 2018: Inorganic Chemistry
Julien Ramade, Léon Marcel Andriambariarijaona, Violette Steinmetz, Nicolas Goubet, Laurent Legrand, Thierry Barisien, Frédérick Bernardot, Christophe Testelin, Emmanuel Lhuillier, Alberto Bramati, Maria Chamarro
All inorganic CsPbX3 (X = Cl, Br, I) nanocrystals (NCs) belong to the novel class of confined metal-halide perovskites which are currently arousing enthusiasm and stimulating huge activity across several fields of optoelectronics due to outstanding properties. A deep knowledge of the band-edge excitonic properties of these materials is thus crucial to further optimize their performances. Here, high-resolution photoluminescence (PL) spectroscopy of single bromide-based NCs reveals the exciton fine structure in the form of sharp peaks that are linearly polarized and grouped in doublets or triplets, which directly mirror the adopted crystalline structure, tetragonal (D4h symmetry) or orthorhombic (D2h symmetry)...
March 21, 2018: Nanoscale
Jianguo Wang, Nan Chen, Chuanping Feng, Miao Li
To obtain an economical and effective adsorbent for fluoride removal, lanthanum-loaded pomelo peel biochar (PPBC-La) was synthesized using a facile approach. The batch adsorption experiments were investigated to determine adsorbent performance. The PPBC-La and its pristine biochar (PPBC) were characterized by scanning electronic microscopy (SEM), zeta potential, Brunauer-Emmett-Teller (BET), Fourier transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS) methods. Experimental results showed that the adsorption data were described well by the pseudo-second-order kinetic and Freundlich isotherm models...
March 21, 2018: Environmental Science and Pollution Research International
Kazuaki Tokuhashi, Kenji Takizawa, Shigeo Kondo
The rate constants of OH radicals with CF3 CF=CCl2 , CF3 CH=CF2 , CF3 CF=CH2 , CF3 CH=CH2 , and (CF3 )2 C=CH2 have been measured over the temperature range 250-430 K. Kinetic measurements have been carried out using flash photolysis and laser photolysis methods combined respectively with laser-induced fluorescence technique. The Arrhenius rate parameters have been determined as k(CF3 CF=CCl2 ) = (6.50 ± 0.22) × 10-13 ∙exp[(200 ± 10)/T], k(CF3 CH=CF2 ) = (4.85 ± 0.14) × 10-13 ∙exp[(120 ± 10)/T], k(CF3 CF=CH2 ) = (1...
March 20, 2018: Environmental Science and Pollution Research International
Bernadette U Ukah, Ogbonnaya Igwe, Peter Ameh
In Ajao Estate, it is believed that poor quality of its groundwater is unconnected to the dislodging of wastewater into the environment by food- and wine-producing industries operating in the area. To ascertain this claim, the impact of this wastewater on microbiological and physicochemical quality of the groundwater was evaluated. Microbiological result of water samples revealed decrease in Staphylococcus aureus, Clostridium spp., Escherichia coli, etc. count from the industrial wastewater dislodging point...
March 20, 2018: Environmental Monitoring and Assessment
Sang Beom Kim, Sook Joung Lee, Kyeong Woo Lee, Jong Hwa Lee, Dong Won Kim
Objective: To demonstrate the usefulness of early videofluoroscopic swallowing study (VFSS) and to investigate change patterns in dietary methods in stroke patients with dysphagia. Methods: The VFSS was performed within 7 days of stroke onset in neurologically stable patients. The patients were divided into three groups according to type of brain lesion: cortical lesion (CL), subcortical lesion (SCL), and brainstem/cerebellar lesion (BCL). Based on the VFSS results, this study investigated change patterns in feeding method and discrepancies in the aspiration risk predicted by the Water Swallowing Test (WST) and the VFSS...
February 2018: Annals of Rehabilitation Medicine
Núria Baños, Carla Julià, Núria Lorente, Silvia Ferrero, Teresa Cobo, Eduard Gratacos, Montse Palacio
Background  Short cervical length (CL) has not been shown to be adequate as a single predictor of spontaneous preterm birth (sPTB) in high-risk pregnancies. Objective  The objective of this study was to evaluate the performance of the mid-trimester cervical consistency index (CCI) to predict sPTB in a cohort of high-risk pregnancies and to compare the results with those obtained with the CL. Study Design  Prospective cohort study including high-risk singleton pregnancies between 19+0 and 24+6 weeks. The ratio between the anteroposterior diameter of the uterine cervix at maximum compression and at rest was calculated offline to obtain the CCI...
January 2018: American Journal of Perinatology Reports
Yi Zhang, Jielin Pan, Qilan Xu, Hao Li, Jianhao Wang, Chao Zhang, Guobin Hong
Objective: To construct carcinoma vascular endothelial-targeted polymeric nanomicelles with high magnetic resonance imaging (MRI) sensitivity and to evaluate their biological safety and in vitro tumor-targeting effect, and to monitor their feasibility using clinical MRI scanner. Method: Amphiphilic block copolymer, poly(ethylene glycol)- b -poly(ε-caprolactone) (PEG-PCL) was synthesized via the ring-opening polymerization of ε-caprolactone (CL) initiated by poly(ethylene glycol) (PEG), in which cyclic pentapeptide Arg-Gly-Asp (cRGD) was conjugated with the terminal of hydrophilic PEG block...
2018: International Journal of Medical Sciences
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"