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https://www.readbyqxmd.com/read/28414799/comprehensive-evaluation-of-ten-deformable-image-registration-algorithms-for-contour-propagation-between-ct-and-cone-beam-ct-images-in-adaptive-head-neck-radiotherapy
#1
Xin Li, Yuyu Zhang, Yinghua Shi, Shuyu Wu, Yang Xiao, Xuejun Gu, Xin Zhen, Linghong Zhou
Deformable image registration (DIR) is a critical technic in adaptive radiotherapy (ART) for propagating contours between planning computerized tomography (CT) images and treatment CT/cone-beam CT (CBCT) images to account for organ deformation for treatment re-planning. To validate the ability and accuracy of DIR algorithms in organ at risk (OAR) contour mapping, ten intensity-based DIR strategies, which were classified into four categories-optical flow-based, demons-based, level-set-based and spline-based-were tested on planning CT and fractional CBCT images acquired from twenty-one head & neck (H&N) cancer patients who underwent 6~7-week intensity-modulated radiation therapy (IMRT)...
2017: PloS One
https://www.readbyqxmd.com/read/28379850/a-novel-geometry-dosimetry-label-fusion-method-in-multi-atlas-segmentation-for-radiotherapy-a-proof-of-concept-study
#2
Jina Chang, Zhen Tian, Weiguo Lu, Xuejun Gu, Mingli Chen, Steve B Jiang
Multi-atlas segmentation (MAS) has been widely used to automate the delineation of organs at risk (OARs) for radiotherapy. Label fusion is a crucial step in MAS to cope with the segmentation variabilities among multiple atlases. However, most existing label fusion methods do not consider the potential dosimetric impact of the segmentation result. In this proof-of-concept study, we propose a novel geometry-dosimetry label fusion method for MAS-based OAR auto-contouring, which evaluates the segmentation performance in terms of both geometric accuracy and the dosimetric impact of the segmentation accuracy on the resulting treatment plan...
April 5, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28367193/prevalence-and-causes-of-visual-impairment-among-saudi-adults
#3
Mujeeb Ur Rehman Parrey, Farhan Khashim Alswelmi
OBJECTIVE: To evaluate the prevalence and causes of visual impairment (VI) among Saudi adults in Arar City, the capital of Northern Border Region of Saudi Arabia. METHODS: This population-based cross-sectional study was conducted on 705 Saudi adults aged 18 years and older. All participants underwent ophthalmic examination including visual acuity (VA) testing, auto refraction, intraocular pressure (IOP) measurement and fundus examination. RESULTS: In the present study 166 cases (23...
January 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28339103/iterative-dataset-optimization-in-automated-planning-implementation-for-breast-and-rectal-cancer-radiotherapy
#4
Jiawei Fan, Jiazhou Wang, Zhen Zhang, Weigang Hu
PURPOSE: To develop a new automated treatment planning solution for breast and rectal cancer radiotherapy. METHODS: The automated treatment planning solution developed in this study includes selection of the iterative optimized training dataset, dose volume histogram (DVH) prediction for the organs at risk (OARs), and automatic generation of clinically acceptable treatment plans. The iterative optimized training dataset is selected by an iterative optimization from 40 treatment plans for left-breast and rectal cancer patients who received radiation therapy...
March 24, 2017: Medical Physics
https://www.readbyqxmd.com/read/28300376/moving-gpu-opencl-based-monte-carlo-dose-calculation-toward-clinical-use-automatic-beam-commissioning-and-source-sampling-for-treatment-plan-dose-calculation
#5
Zhen Tian, Yongbao Li, Nima Hassan-Rezaeian, Steve B Jiang, Xun Jia
We have previously developed a GPU-based Monte Carlo (MC) dose engine on the OpenCL platform, named goMC, with a built-in analytical linear accelerator (linac) beam model. In this paper, we report our recent improvement on goMC to move it toward clinical use. First, we have adapted a previously developed automatic beam commissioning approach to our beam model. The commissioning was conducted through an optimization process, minimizing the discrepancies between calculated dose and measurement. We successfully commissioned six beam models built for Varian TrueBeam linac photon beams, including four beams of different energies (6 MV, 10 MV, 15 MV, and 18 MV) and two flattening-filter-free (FFF) beams of 6 MV and 10 MV...
March 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28297355/mr-image-based-synthetic-ct-for-imrt-prostate-treatment-planning-and-cbct-image-guided-localization
#6
Shupeng Chen, Hong Quan, An Qin, Seonghwan Yee, Di Yan
The purpose of this study was to propose and evaluate a method of creating a synthetic CT (S-CT) from MRI simulation for dose calculation and daily CBCT localization. A pair of MR and CT images was obtained in the same day from each of 10 prostate patients. The pair of MR and CT images was preregistered using the deformable image registration (DIR). Using the corresponding displacement vector field (atlas-DVF), the CT image was deformed to the MR image to create an atlas MR-CT pair. Regions of interest (ROI) on the atlas MR-CT pair were delineated and used to create atlas-ROI masks...
May 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28293422/regional-disparities-in-immunization-services-in-ghana-through-a-bottleneck-analysis-approach-implications-for-sustaining-national-gains-in-immunization
#7
A E Yawson, G Bonsu, L K Senaya, A O Yawson, J B Eleeza, J K Awoonor-Williams, H K Banskota, E E A Agongo
BACKGROUND: Immunization is considered one of the most cost effective public health interventions for reducing child morbidity, mortality and disability. The aim of this work is to describe the application of the Bottleneck analysis (BNA) process to assess gaps in immunization services in Ghana and implications for sustaining the gains in Immunization coverage. METHODS: A national assessment was conducted in May 2015, through use of desk reviews, field visits and key informant interviews...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/28273740/automatic-image-fusion-of-real-time-ultrasound-with-computed-tomography-images-a-prospective-comparison-between-two-auto-registration-methods
#8
Dong Ik Cha, Min Woo Lee, Ah Yeong Kim, Tae Wook Kang, Young-Taek Oh, Ja-Yeon Jeong, Jung-Woo Chang, Jiwon Ryu, Kyong Joon Lee, Jaeil Kim, Won-Chul Bang, Dong Kuk Shin, Sung Jin Choi, Dalkwon Koh, Bong Koo Seo, Kyunga Kim
Background A major drawback of conventional manual image fusion is that the process may be complex, especially for less-experienced operators. Recently, two automatic image fusion techniques called Positioning and Sweeping auto-registration have been developed. Purpose To compare the accuracy and required time for image fusion of real-time ultrasonography (US) and computed tomography (CT) images between Positioning and Sweeping auto-registration. Material and Methods Eighteen consecutive patients referred for planning US for radiofrequency ablation or biopsy for focal hepatic lesions were enrolled...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28268814/a-machine-learning-framework-for-auto-classification-of-imaging-system-exams-in-hospital-setting-for-utilization-optimization
#9
Meru A Patil, Ravindra B Patil, P Krishnamoorthy, Jacob John
In clinical environment, Interventional X-Ray (IXR) system is used on various anatomies and for various types of the procedures. It is important to classify correctly each exam of IXR system into respective procedures and/or assign to correct anatomy. This classification enhances productivity of the system in terms of better scheduling of the Cath lab, also provides means to perform device usage/revenue forecast of the system by hospital management and focus on targeted treatment planning for a disease/anatomy...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28237294/automatic-planning-on-hippocampal-avoidance-whole-brain-radiotherapy
#10
Shuo Wang, Dandan Zheng, Chi Zhang, Rongtao Ma, Nathan R Bennion, Yu Lei, Xiaofeng Zhu, Charles A Enke, Sumin Zhou
Mounting evidence suggests that radiation-induced damage to the hippocampus plays a role in neurocognitive decline for patients receiving whole-brain radiotherapy (WBRT). Hippocampal avoidance whole-brain radiotherapy (HA-WBRT) has been proposed to reduce the putative neurocognitive deficits by limiting the dose to the hippocampus. However, urgency of palliation for patients as well as the complexities of the treatment planning may be barriers to protocol enrollment to accumulate further clinical evidence. This warrants expedited quality planning of HA-WBRT...
April 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28227009/a-machine-learning-framework-for-auto-classification-of-imaging-system-exams-in-hospital-setting-for-utilization-optimization
#11
Meru A Patil, Ravindra B Patil, P Krishnamoorthy, Jacob John, Meru A Patil, Ravindra B Patil, P Krishnamoorthy, Jacob John, Meru A Patil, Jacob John, Ravindra B Patil, P Krishnamoorthy
In clinical environment, Interventional X-Ray (IXR) system is used on various anatomies and for various types of the procedures. It is important to classify correctly each exam of IXR system into respective procedures and/or assign to correct anatomy. This classification enhances productivity of the system in terms of better scheduling of the Cath lab, also provides means to perform device usage/revenue forecast of the system by hospital management and focus on targeted treatment planning for a disease/anatomy...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224184/irritable-temperament-profile-prevails-among-patients-with-boxer-fractures
#12
A Taşkesen, I Demirkale, N Taşkesen, M Okumuş, D Ö Can
OBJECTIVE: The purpose of this prospective study was to examine the temperament dimensions of the patients with boxer fracture and compare them with age- and sex-matched controls. METHODS: We performed a prospective analysis investigating affective temperaments of the 102 patients with boxer fractures and compared them with 100 sex- and age-matched controls that were referred to the emergency department due to incidental soft-tissue trauma. Affective temperament of the patients was evaluated by Memphis, Pisa, Paris, and San Diego-Auto questionnaire (TEMPS-A)...
February 21, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28202228/cross-institutional-knowledge-based-planning-kbp-implementation-and-its-performance-comparison-to-auto-planning-engine-ape
#13
Binbin Wu, Martijn Kusters, Martina Kunze-Busch, Tim Dijkema, Todd McNutt, Giuseppe Sanguineti, Karl Bzdusek, Anatoly Dritschilo, Dalong Pang
BACKGROUND AND PURPOSE: To investigate (1) whether a plan library established at one institution can be applied for another institution's knowledge-based planning (KBP); (2) the performance of cross-institutional KBP compared to Auto-Planning Engine (APE). MATERIAL AND METHODS: Radboud University Medical Center (RUMC) provided 35 oropharyngeal cancer patients (68Gy to PTV(68) and 50.3Gy to PTV(50.3)) with clinically-delivered and comparative APE plans. The Johns Hopkins University (JHU) contributed a three-dose-level plan library consisting of 179 clinically-delivered plans...
February 12, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28196288/clinical-adequacy-assessment-of-auto-contours-for-prostate-imrt-with-meaningful-endpoints
#14
Hamidreza Nourzadeh, William T Watkins, Mahmoud Ahmad, Cheukkai Hui, David Schlesinger, Jeffrey V Siebers
PURPOSE: To determine if radiation treatment plans created based on auto-segmented (AS) regions-of-interest (ROI)s are clinically equivalent to plans created based on manually segmented ROIs, where equivalence is evaluated using probabilistic dosimetric metrics and probabilistic biological endpoints for prostate IMRT. METHOD AND MATERIALS: Manually drawn contours and auto-segmented ROIs were created for 167 CT image sets acquired from 19 prostate patients. Auto-segmentation was performed utilizing Pinnacle's Smart Probabilistic Image Contouring Engine...
February 14, 2017: Medical Physics
https://www.readbyqxmd.com/read/28194514/a-prospective-comparison-between-auto-registration-and-manual-registration-of-real-time-ultrasound-with-mr-images-for-percutaneous-ablation-or-biopsy-of-hepatic-lesions
#15
Dong Ik Cha, Min Woo Lee, Kyoung Doo Song, Young-Taek Oh, Ja-Yeon Jeong, Jung-Woo Chang, Jiwon Ryu, Kyong Joon Lee, Jaeil Kim, Won-Chul Bang, Dong Kuk Shin, Sung Jin Choi, Dalkwon Koh, Bong Koo Seo, Kyunga Kim
PURPOSE: To compare the accuracy and required time for image fusion of real-time ultrasound (US) with pre-procedural magnetic resonance (MR) images between positioning auto-registration and manual registration for percutaneous radiofrequency ablation or biopsy of hepatic lesions. METHODS: This prospective study was approved by the institutional review board, and all patients gave written informed consent. Twenty-two patients (male/female, n = 18/n = 4; age, 61...
February 13, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28143623/fully-automated-treatment-planning-of-spinal-metastases-a-comparison-to-manual-planning-of-volumetric-modulated-arc-therapy-for-conventionally-fractionated-irradiation
#16
Daniel Buergy, Abdul Wahab M Sharfo, Ben J M Heijmen, Peter W J Voet, Sebastiaan Breedveld, Frederik Wenz, Frank Lohr, Florian Stieler
BACKGROUND: Planning for Volumetric Modulated Arc Therapy (VMAT) may be time consuming and its use is limited by available staff resources. Automated multicriterial treatment planning can eliminate this bottleneck. We compared automatically created (auto) VMAT plans generated by Erasmus-iCycle to manually created VMAT plans for treatment of spinal metastases. METHODS: Forty-two targets in 32 patients were analyzed. Lungs and kidneys were defined as organs at risk (OARs)...
January 31, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28126329/head-and-neck-target-delineation-using-a-novel-pet-automatic-segmentation-algorithm
#17
B Berthon, M Evans, C Marshall, N Palaniappan, N Cole, V Jayaprakasam, T Rackley, E Spezi
PURPOSE: To evaluate the feasibility and impact of using a novel advanced PET auto-segmentation method in Head and Neck (H&N) radiotherapy treatment (RT) planning. METHODS: ATLAAS, Automatic decision Tree-based Learning Algorithm for Advanced Segmentation, previously developed and validated on pre-clinical data, was applied to (18)F-FDG-PET/CT scans of 20 H&N patients undergoing Intensity Modulated Radiation Therapy. Primary Gross Tumour Volumes (GTVs) manually delineated on CT/MRI scans (GTVpCT/MRI), together with ATLAAS-generated contours (GTVpATLAAS) were used to derive the RT planning GTV (GTVpfinal)...
January 23, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28067870/a-single-center-s-experience-using-four-different-front-line-mobilization-strategies-in-lymphoma-patients-planned-to-undergo-autologous-hematopoietic-cell-transplantation
#18
B M Haverkos, Y Huang, P Elder, L O'Donnell, D Scholl, B Whittaker, S Vasu, S Penza, L A Andritsos, S M Devine, S M Jaglowski
In an otherwise eligible patient with relapsed lymphoma, inadequate mobilization of hematopoietic stem cells (HSCs) is a limiting factor to proceeding with an autologous hematopoietic cell transplantation (auto-HCT). Multiple strategies have been used to mobilize an adequate number of HSCs with no obvious front-line strategy. We report a single institutional experience mobilizing HSCs using four different approaches in lymphoma patients. We prospectively collected mobilization outcomes on patients planned to undergo auto-HCT at Ohio State University...
April 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28048691/tu-ab-brc-11-moving-a-gpu-opencl-based-monte-carlo-mc-dose-engine-towards-routine-clinical-use-automatic-beam-commissioning-and-efficient-source-sampling
#19
Z Tian, Y Li, M Folkerts, S Jiang, X Jia
PURPOSE: We have previously developed a GPU-OpenCL-based MC dose engine named goMC with built-in analytical linac beam model. To move goMC towards routine clinical use, we have developed an automatic beam-commissioning method, and an efficient source sampling strategy to facilitate dose calculations for real treatment plans. METHODS: Our commissioning method is to automatically adjust the relative weights among the sub-sources, through an optimization process minimizing the discrepancies between calculated dose and measurements...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048553/su-c-brb-03-cross-institutional-validation-of-an-ultrafast-automatic-planning-platform-for-breast-irradiation
#20
T Li, Y Sheng, V Lockamy, P Anne, N Simone, Q J Wu, Y Yu
PURPOSE: Recently an ultrafast automatic planning system for breast irradiation using tangential beams was developed by modeling relationships between patient anatomy and achieved dose distribution. This study evaluates the performance of this system when applied to a different patient population and dose calculation algorithm. METHODS: The system and its anatomy-to-dose models was developed at institution A based on 20 cases, which were planned using manual fluence painting technique and calculated WITH heterogeneity correction...
June 2016: Medical Physics
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