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Chung-Chih Lin, Hsin-Cheng Lin, Wen-Yo Lee, Shih-Tseng Lee, Chieh-Tsai Wu
BACKGROUND: The aim of this work was to develop a neurosurgical robotic arm drilling navigation system that provides assistance throughout the complete bone drilling process. METHODS: The system comprised neurosurgical robotic arm navigation combining robotic and surgical navigation, 3D medical imaging based surgical planning that could identify lesion location and plan the surgical path on 3D images, and automatic bone drilling control that would stop drilling when the bone was to be drilled-through...
December 2, 2016: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
A Stensgaard, A DunnGalvin, D Nielsen, M Munch, C Bindslev-Jensen
BACKGROUND: Adolescents have the highest risk for food allergy-related fatalities. Our main aim was to investigate the level of risk in everyday social situations as perceived by adolescents/young adults with peanut allergy, their families and their friends. METHODS: The web-based 'Colours Of Risks' (COR) questionnaire was completed by 70 patients (aged 12-23 years), 103 mothers and fathers, 31 siblings (aged 12-26 years), and 42 friends (aged 12-24 years). COR deals with six main contexts (home, school/university, work, visiting/social activities, special occasions/parties, and vacations), each with 1-12 items...
November 25, 2016: Allergy
Kai You, Robert L Strawderman, Yue Li
Medicare Part D has been successful in providing affordable prescription drug coverage with relatively high levels of beneficiary reported satisfaction. We use nationally representative survey data to examine whether racial/ethnic disparities exist in reported Part D satisfaction and plan evaluations. Compared to non-Hispanic white Medicare beneficiaries, Hispanic beneficiaries are considerably more likely to report to switch to a new plan in the next year and, among beneficiaries auto-enrolled in a Part D plan, are less likely to be very satisfied with the currently enrolled plan...
November 23, 2016: Journal of Aging & Social Policy
Chandresh Jaiswara, Vinay K Srivastava, Neeraj Dhiman
: Esthetics is a prime concern for a young lady. Any anomaly in the anterior tooth may create anxiety and depression. This anxiety and depression may hamper her married life and overall personality. This case report reveals an unerupted right central incisor situated in a strange position, creating space in the maxillary anterior region and giving an unesthetic appearance. Autotransplantation is a method of choice for a strangely positioned impacted central incisor in a new appropriate site...
July 2016: International Journal of Clinical Pediatric Dentistry
Deborah Gleeson
Between the 10 May and 18 July 2016, St Helens and Knowsley Teaching Hospitals NHS Trust conducted a small, non-controlled evaluation set out to assess the performance of the Apex Pro-care Auto pressure-relieving mattress in an acute stroke ward. Seven patients, assessed as being at medium-to-high risk of developing a pressure ulcer (PU), were recruited into the evaluation; the mean age was 73.1 years. Three patients were bed bound and four had restricted mobility. The average length of time spent on the mattress was 31 days...
November 10, 2016: British Journal of Nursing: BJN
Jing Lu, Xiang-Dong Sun, Xi Yang, Xin-Yu Tang, Qin Qin, Hong-Cheng Zhu, Hong-Yan Cheng, Xin-Chen Sun
PURPOSE: With the advances in radiotracers, positron emission tomography/computed tomography (PET/CT) is recognized as a useful adjunct to anatomic imaging with CT, MRI and endoscopic ultrasonography (EUS). The objective of this review was to comprehensively analyze the roles of PET/CT for the radiotherapy of esophageal cancer. METHODS: In this review, we focused on issues concerning the application of PET/CT in TNM staging, target volume delineation and response to therapy, both for the primary tumor and regional lymph nodes...
November 2016: Critical Reviews in Oncology/hematology
T Doshi, C Wilson, C Paterson, C Lamb, A James, K MacKenzie, J Soraghan, L Petropoulakis, G Di Caterina, D Grose
AIMS: To carry out statistical validation of a newly developed magnetic resonance imaging (MRI) auto-contouring software tool for gross tumour volume (GTV) delineation in head and neck tumours to assist in radiotherapy planning. MATERIALS AND METHODS: Axial MRI baseline scans were obtained for 10 oropharyngeal and laryngeal cancer patients. GTV was present on 102 axial slices and auto-contoured using the modified fuzzy c-means clustering integrated with the level set method (FCLSM)...
October 22, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
Marcus Sonier, William Chu, Nafisha Lalani, Darby Erler, Patrick Cheung, Renee Korol
To develop a volumetric modulated arc therapy (VMAT) treatment planning solution in the treatment of primary renal cell carcinoma and oligometastatic adrenal lesions with stereotactic body radiation therapy. Single-arc VMAT plans (n = 5) were compared with clinically delivered step-and-shoot intensity-modulated radiotherapy (IMRT) with planning target volume coverage normalized between techniques. Target volume conformity, organ-at-risk (OAR) dose, treatment time, and monitor units were compared. A VMAT planning solution, created from a combination of arc settings and optimization constraints, auto-generated treatment plans in a single optimization...
October 13, 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
Vaitheeswaran Ranganathan, K Joseph Maria Das
AIM: An empirical scheme called "anatomy-guided segment counting (AGSC)" is proposed for automatic selection of maximum number of segments (NOS) for direct machine parameter optimization (DMPO). BACKGROUND: Direct machine parameter optimization (DMPO) requires the user to define the maximum number of segments (NOS) in order to proceed with an optimization process. Till date there is no established approach to arrive at an optimal and case-specific maximum NOS in DMPO, and this step is largely left to the planner's experience...
November 2016: Reports of Practical Oncology and Radiotherapy
Y B He, L Bai, T Li, X W Ji, Aji Tuerganaili, Y Jiang, J M Zhao, Y M Shao, W Y Liu, H Wen
OBJECTIVE: To determine the clinical value of three-dimensional(3D) visualization technology in pre-operative assessment and surgical planning for patients with hepatic alveolar echinococcosis. METHODS: Eighty-five hepatic alveolar echinococcosis patients received surgical treatment in the First Affiliated Hospital of Xinjiang Medical University between May 2011 and May 2015.3D reconstruction and virtual surgeries were performed on diseased livers using a 3D visualization reconstruction system for liver, which based on the data set of 64-slice CT from those patients and indicated the feasibility and safety of liver resection...
September 1, 2016: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
Qianglin Zeng, Dandan Li, Gui Huang, Jin Xia, Xiaoming Wang, Yamei Zhang, Wanping Tang, Hui Zhou
Short-term forecast of pertussis incidence is helpful for advanced warning and planning resource needs for future epidemics. By utilizing the Auto-Regressive Integrated Moving Average (ARIMA) model and Exponential Smoothing (ETS) model as alterative models with R software, this paper analyzed data from Chinese Center for Disease Control and Prevention (China CDC) between January 2005 and June 2016. The ARIMA (0,1,0)(1,1,1)12 model (AICc = 1342.2 BIC = 1350.3) was selected as the best performing ARIMA model and the ETS (M,N,M) model (AICc = 1678...
2016: Scientific Reports
Lisa Durrant, Maxwell Robinson, Maria A Hawkins, Frank Van den Heuvel, Rebecca Muirhead
BACKGROUND AND PURPOSE: Intensity modulated radiotherapy requires all target areas to be treated by a single radiotherapy plan. In anal cancer, the pelvic nodes, inguinal nodes and primary tumour represent three different targets. We aim to calculate target-specific motion in anal cancer radiotherapy, when delivered using a single pelvic online auto-match. MATERIALS AND METHODS: Twenty consecutive patients treated using IMRT at a single institution were studied...
October 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
Leonard Fromer
Anaphylaxis is a life-threatening condition, with at-risk individuals remaining at chronic high risk of recurrence. Anaphylaxis is frequently underrecognized and undertreated by healthcare providers. The first-line pharmacologic intervention for anaphylaxis is epinephrine, and guidelines uniformly agree that its prompt administration is vital to prevent progression, improve patient outcomes, and reduce hospitalizations and fatalities. Healthcare costs potentially associated with failure to provide epinephrine (hospitalizations and emergency department visits) generally exceed those of its provision...
December 2016: American Journal of Medicine
Thomas J Povsic, Timothy D Henry, Jay H Traverse, F David Fortuin, Gary L Schaer, Dean J Kereiakes, Richard A Schatz, Andreas M Zeiher, Christopher J White, Duncan J Stewart, E Marc Jolicoeur, Theodore Bass, David A Henderson, Patricia Dignacco, Ziangoiong Gu, Hussein R Al-Khalidi, Candice Junge, Adel Nada, Andrea S Hunt, Douglas W Losordo
OBJECTIVES: This study tested whether intramyocardial (IM) administration of mobilized, purified autologous CD34(+) cells would improve total exercise time (TET) and angina frequency in patients with refractory angina. BACKGROUND: IM administration of autologous CD34(+) cells has been associated consistently with improvements in functional capacity and angina symptoms in early phase clinical trials. METHODS: RENEW (Efficacy and Safety of Targeted Intramyocardial Delivery of Auto CD34+ Stem Cells for Improving Exercise Capacity in Subjects With Refractory Angina) was a randomized, double-blind, multicenter trial comparing IM CD34(+) administration with no intervention (open-label standard of care) or IM placebo injections (active control)...
August 8, 2016: JACC. Cardiovascular Interventions
Philippe Lewalle, Sebastian Wittnebel
PURPOSE OF REVIEW: The treatment of high-risk classic Hodgkin lymphoma (cHL) patients remains challenging, especially after autologous stem cell transplant (ASCT) failure. Moreover, the outcome of chemorefractory patients is still poor. RECENT FINDINGS: The development of novel targeted therapies has changed the therapeutic options for high-risk patients. To improve outcome, treatment algorithms should integrate up-front, newly established prognostic markers. Tandem ASCT instead of single ASCT has been proposed as an option to improve outcome for high-risk patients...
September 2016: Current Opinion in Oncology
Shaoqi Tian, Yuanhe Wang, Bin Wang, Lun Liu, Chengzhi Ha, Qicai Li, Kang Sun
PURPOSE: To compare the clinical outcome of anatomic double-bundle (DB) anterior cruciate ligament (ACL) reconstruction with a hamstring tendon autograft versus fresh-frozen allograft. METHODS: Between January 2010 and December 2011, in a prospective randomized study, we included 157 patients who were planned to receive anatomic DB ACL reconstruction with a hamstring tendon autograft or fresh-frozen allograft. All surgeries were performed by the same senior surgeon with the DB reconstruction technique...
June 8, 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
Sofia F Garcia, Sheetal M Kircher, Megan Oden, Aubri Veneruso, June M McKoy, Timothy Pearman, Frank J Penedo
Cancer survivorship care plans (SCPs) have been recommended to improve clinical care and patient outcomes. Research is needed to establish their efficacy and identify best practices. Starting in 2015, centers accredited by the American College of Surgeons Commission on Cancer must deliver SCPs to patients completing primary cancer treatment with curative intent. We describe how we established routine SCP delivery at the Robert H Lurie Comprehensive Cancer Center in Chicago, Illinois, using the Quality Implementation Framework...
May 2016: Journal of Community and Supportive Oncology
Alexander Bischoff
BACKGROUND: In 2007, the Tanzanian government called for improvements in its primary health care services. Part of this initiative was to accelerate the training rate for nurses qualified to work in rural areas. The aim of this study was to reflect on the issues experienced whilst establishing and implementing a faith-based organisation (FBO) nursing school and make recommendations for other similar initiatives. DESIGN: This paper describes an auto-ethnographic case study design to identify the key difficulties involved with establishing and implementing a new nursing school, and which factors helped the project achieve its goals...
2016: Global Health Action
Jose Dolz, Nacim Betrouni, Mathilde Quidet, Dris Kharroubi, Henri A Leroy, Nicolas Reyns, Laurent Massoptier, Maximilien Vermandel
Delineation of organs at risk (OARs) is a crucial step in surgical and treatment planning in brain cancer, where precise OARs volume delineation is required. However, this task is still often manually performed, which is time-consuming and prone to observer variability. To tackle these issues a deep learning approach based on stacking denoising auto-encoders has been proposed to segment the brainstem on magnetic resonance images in brain cancer context. Additionally to classical features used in machine learning to segment brain structures, two new features are suggested...
September 2016: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
Vaitheeswaran Ranganathan, K J Maria Das
This paper aims to introduce an algorithm called "sensitivity-based beam number selection (SBBNS)" for fully automated and case-specific determination of an optimal number of equispaced beams in intensity-modulated radiotherapy (IMRT). We tested the algorithm in five head and neck cases of varying complexity. We used direct machine parameter optimization method coupled with Auto Plan feature available in Pinnacle TPS (Version 9.10.0) for optimization. The Pearson correlation test shows a correlation of 0.88 between predicted and actual optimal number of beams, which indicates that SBBNS method is capable of predicting optimal number of beams for head and neck cases with reasonable accuracy...
April 2016: Journal of Medical Physics
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