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Thinking outside the box

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https://www.readbyqxmd.com/read/28432171/ascites-in-a-patient-with-episodic-angio-oedema-and-eosinophilia-thinking-outside-the-box
#1
Eirini I Rigopoulou, Maria Ioannou, Georgia Papadamou, Georgios N Dalekos
Episodic angio-oedema with eosinophilia (EAE) or Gleich's syndrome is a rare condition characterised by recurrent episodes of oedema and eosinophilia, accompanied by urticaria, fever and weight gain. The presence of ascites has not been reported so far. We report a 21-year-old Caucasian woman who presented with marked ocular oedema and ascites. Laboratory evaluation revealed marked eosinophilia. During the last 3 months, three episodes of facial and neck oedema were reported, which resolved spontaneously over a period of 3-5 days...
April 21, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28427333/the-experiences-of-physiotherapists-treating-people-with-dementia-who-fracture-their-hip
#2
A J Hall, R Watkins, I A Lang, R Endacott, V A Goodwin
BACKGROUND: It is estimated that people with dementia are approximately three times more likely to fracture their hip than sex and age matched controls. A report by the Chartered Society of Physiotherapy found that this population have poor access to rehabilitation as inpatients and in the community. A recent scoping review found a paucity of research in this area, indeed there has been no qualitative research undertaken with physiotherapists. In order to address this evidence gap, the aim of this current study was to explore the experiences of physiotherapists treating this population...
April 20, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28422918/reassessing-the-cardiac-box-a-comprehensive-evaluation-of-the-relationship-between-thoracic-gunshot-wounds-and-cardiac-injury
#3
Rashi Jhunjhunwala, Michael J Mina, Elizabeth I Roger, Christopher J Dente, Michael Heninger, Jacquelyn S Carr, Stacy D Dougherty, Rondi B Gelbard, Jeffrey M Nicholas, Amy D Wyrzykowski, David V Feliciano, Bryan C Morse
BACKGROUND: High energy missiles can cause cardiac injury regardless of entrance site. This study assesses the adequacy of the anatomic borders of the current "cardiac box" to predict cardiac injury. METHODS: Retrospective autopsy review was performed to identify patients with penetrating torso gunshot wounds 2011-2013. Using a circumferential grid system around the thorax, logistic regression analysis was performed to detect differences in rates of cardiac injury from entrance/exit wounds in the "cardiac box" vs...
April 18, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28393387/dental-students-reflections-about-long-term-care-experiences-through-an-existing-model-of-oral-health
#4
Mario Brondani, Komkham Pattanaporn
OBJECTIVE: The aim of this study was to explore students' reflective thinking about long-term care experiences from the perspective of a model of oral health. MATERIALS AND METHODS: A total of 186 reflections from 193 second-year undergraduate dental students enrolled between 2011/12 and 2014/15 at the University of British Columbia were explored qualitatively. Reflections had a word limit of 300, and students were asked to relate an existing model of oral health to their long-term care experiences...
April 10, 2017: Gerodontology
https://www.readbyqxmd.com/read/28380677/thinking-outside-the-box
#5
EDITORIAL
Claire Su-Yeon Park
Much evidence supports that having more nurses leads to better patient outcomes. However, why is nurse staffing still lacking in practice? Previous studies on the nursing workforce have, so far, focused on determining 'more nurses and better patient outcomes.' However, a controversial debate on the cost-effectiveness of hiring more nurses still continues (Aiken et al. 2011). When it comes to nursing workforce policy-materializing in practice, the inconclusiveness of nursing efficiency is considered to be one of the critical reasons for the failure to narrow the gap between the ideal and the real...
April 5, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28376665/thinking-outside-the-box
#6
Judith Ingles, Chandrashekara N Kyathanahalli, Pancharatnam Jeyasuria, Jennifer C Condon
A broad definition of preconditioning is "the preparation for a subsequent action." Mounting evidence demonstrates that novel remote preconditioning paradigms, in which protective stimuli experienced locally can capacitate systemic tolerance and enhanced cell viability upon exposure to ensuing cellular insults, have been largely successful in the field of cardiovascular ischemia/reperfusion injury. To ensure successful protective preconditioning, some models (including the uterus) have been demonstrated to activate the unfolded protein response (UPR), which is a cellular stress response controlled at the level of the endoplasmic reticulum...
January 1, 2017: Journal of Cardiovascular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28231260/effects-of-the-skills4genius-sports-based-training-program-in-creative-behavior
#7
Sara Santos, Sergio Jiménez, Jaime Sampaio, Nuno Leite
Team Sports has been suggested as a suitable environment to investigate creative behavior. This study's purpose was two-fold: first, it intended to identify the effects of the Skills4Genius sports-bases training program in thinking, motor, and in-game creative behavior in team sports. Second, it aimed to investigate the relationship between creative thinking and in-game creativity. Forty children from primary school were allocated into control (n = 18, age: 9.2±0.4) and experimental (n = 22, age: 9.5±0.7) groups...
2017: PloS One
https://www.readbyqxmd.com/read/28029472/the-role-of-interventional-cardiology-to-our-understanding-of-basic-mechanisms-related-to-coronary-atherosclerosis-thinking-outside-the-box
#8
REVIEW
Konstantinos Dean Boudoulas, Christodoulos Stefanadis, Harisios Boudoulas, Hon
Interventional cardiology has contributed significantly to our understanding of coronary atherosclerosis. Interventional cardiology has allowed a correlation between the clinical picture of coronary atherosclerosis with the underlying pathology and has helped establish the evolution of atherosclerotic plaques in vivo. Better understanding of the basic mechanisms of coronary atherosclerosis, due to the contributions of interventional cardiology, will help cure and/or prevent coronary atherosclerosis in the next few decades...
October 15, 2016: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/28007231/-think-outside-the-box-visionary-of-cross-training
#9
EDITORIAL
Tsuyoshi Kaneko
No abstract text is available yet for this article.
January 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27790469/student-project-in-anatomy-spa-making-the-first-year-medical-students-responsible-and-creative
#10
Satheesha B Nayak, Snigdha Mishra, Bincy M George, Naveen Kumar
INTRODUCTION: Creativity is a combination of ones' capacity to think outside the box, the gained knowledge and the passion for creating something. It very easily and effectively provides the creator a chance to be responsible for his/her creation and acts as a confidence booster for him/her. Creativity is inherent, but needs to be polished and nurtured. If nurtured well through proper motivation, the creator excels leaps and bounds. It develops an empathetic behaviour in the creator, when he allows his creations to be used by others...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27709892/current-challenges-toward-in-vitro-cellular-validation-of-inorganic-nanoparticles
#11
Malou Henriksen-Lacey, Susana Carregal-Romero, Luis M Liz-Marzán
An impressive development has been achieved toward the production of well-defined "smart" inorganic nanoparticles, in which the physicochemical properties can be controlled and predicted to a high degree of accuracy. Nanoparticle design is indeed highly advanced, multimodal and multitargeting being the norm, yet we do not fully understand the obstacles that nanoparticles face when used in vivo. Increased cooperation between chemists and biochemists, immunologists and physicists, has allowed us to think outside the box, and we are slowly starting to understand the interactions that nanoparticles undergo under more realistic situations...
January 18, 2017: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/27707735/when-clinical-heterogeneity-exceeds-genetic-heterogeneity-thinking-outside-the-genomic-box-in-chronic-myelomonocytic-leukemia
#12
REVIEW
Markus Ball, Alan F List, Eric Padron
Exome sequencing studies in chronic myelomonocytic leukemia (CMML) illustrate a mutational landscape characterized by few somatic mutations involving a subset of recurrent gene mutations in ASXL1, SRSF2, and TET2, each approaching 40% in incidence. This has led to the clinical implementation of next-generation sequencing panels that effectively identify clonal monocytosis and complement clinical prognostic scoring systems in most patients. However, most murine models based on single gene mutations fail to recapitulate the CMML phenotype, and many gene mutations are loss of function, making the identification of traditional therapeutic vulnerabilities challenging...
November 17, 2016: Blood
https://www.readbyqxmd.com/read/27680980/pre-emptive-antibiotic-therapy-to-reduce-ventilator-associated-pneumonia-thinking-outside-the-box
#13
Donald E Craven, Jana Hudcova, Yuxiu Lei, Kathleen A Craven, Ahsan Waqas
Mechanically ventilated, intubated patients are at increased risk for tracheal colonization with bacterial pathogens that may progress to heavy bacterial colonization, ventilator-associated tracheobronchitis (VAT), and/or ventilator-associated pneumonia (VAP). Previous studies report that 10 to 30 % of patients with VAT progress to VAP, resulting in increased morbidity and significant acute and chronic healthcare costs. Several natural history studies, randomized, controlled trials, and a meta-analysis have reported antibiotic treatment for VAT can reduce VAP, ventilator days, length of intensive care unit (ICU) stay, and patient morbidity and mortality...
September 29, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27650173/think-outside-the-box-acanthamoeba-encephalitis-following-autologous-haematopoietic-stem-cell-transplantation
#14
Narendranath Epperla, Horatiu Olteanu, Mehdi Hamadani
No abstract text is available yet for this article.
September 21, 2016: British Journal of Haematology
https://www.readbyqxmd.com/read/27648418/socio-cultural-factors-in-the-access-of-women-to-hiv-aids-prevention-and-treatment-services-in-south-southern-nigeria
#15
Edlyne Anugwom, Kenechukwu Anugwom
BACKGROUND: The South-southern zone of Nigeria is one of the zones in the country that has reported consistent high prevalent rates of HIV/AIDS pandemic in the last decade. In spite of bio-medical reasons adduced for the spread of the pandemic, socio-cultural factors may be major issues in the access to both prevention and treatment services especially for women. Hence, this study investigated the socio-cultural factors, which influence the access of women to HIV/AIDS prevention and treatment services in Nigeria...
June 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/27567402/editorial-overview-antimicrobials-fighting-bacterial-infections-in-the-21st-century-thinking-outside-of-the-box
#16
EDITORIAL
Michael J Pucci, Thomas J Dougherty
No abstract text is available yet for this article.
October 2016: Current Opinion in Microbiology
https://www.readbyqxmd.com/read/27530191/thinking-outside-the-box-use-of-the-pressure-wire-to-assess-intracranial-large-artery-stenoses
#17
EDITORIAL
Vani P Sanon, Anand Prasad
A novel study investigating the utility of the 0.014″ diameter pressure wire to assess the hemodynamic significance of intermediate intracranial stenosis. Technical aspects of pressure wire positioning across intracranial arteries are described. Further research is required to clarify the assessment of pressure gradients in the cerebral circulation and to define the optimal threshold for intervention.
August 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27512156/total-radiosynthesis-thinking-outside-the-box
#18
Steven H Liang, Neil Vasdev
The logic of total synthesis transformed a stagnant state of medicinal and synthetic organic chemistry when there was a paucity of methods and reagents to synthesize drug molecules and/or natural products. Molecular imaging by positron emission tomography (PET) is now experiencing a renaissance in the way radiopharmaceuticals for molecular imaging are synthesized, however, a paradigm shift is desperately needed in the discovery pipeline to accelerate in vivo imaging studies. A significant challenge in radiochemistry is the limited choice of labeled reagents (or building blocks) available for the synthesis of novel radiopharmaceuticals with the most commonly used short-lived radionuclides carbon-11 ((11)C; half-life ~20 minutes) and fluorine-18 ((18)F; half-life ~2 hours)...
September 2015: Australian Journal of Chemistry
https://www.readbyqxmd.com/read/27510424/thinking-outside-the-box-orbitofrontal-cortex-imagination-and-how-we-can-treat-addiction
#19
REVIEW
Geoffrey Schoenbaum, Chun-Yun Chang, Federica Lucantonio, Yuji K Takahashi
Addiction involves an inability to control drug-seeking behavior. While this may be thought of as secondary to an overwhelming desire for drugs, it could equally well reflect a failure of the brain mechanisms that allow addicts to learn about and mentally simulate non-drug consequences. Importantly, this process of mental simulation draws upon, but is not normally bound by, our past experiences. Rather we have the ability to think outside the box of our past, integrating knowledge gained from a variety of similar and not-so-similar life experiences to derive estimates or imagine what might happen next...
December 2016: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27458751/representational-account-of-memory-insights-from-aging-and-synesthesia
#20
Gaby Pfeifer, Jamie Ward, Dennis Chan, Natasha Sigala
The representational account of memory envisages perception and memory to be on a continuum rather than in discretely divided brain systems [Bussey, T. J., & Saksida, L. M. Memory, perception, and the ventral visual-perirhinal-hippocampal stream: Thinking outside of the boxes. Hippocampus, 17, 898-908, 2007]. We tested this account using a novel between-group design with young grapheme-color synesthetes, older adults, and young controls. We investigated how the disparate sensory-perceptual abilities between these groups translated into associative memory performance for visual stimuli that do not induce synesthesia...
July 26, 2016: Journal of Cognitive Neuroscience
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