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Morphometry

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https://www.readbyqxmd.com/read/28088107/gaas-laser-therapy-reestablishes-the-morphology-of-the-nmj-and-nachrs-after-injury-due-to-bupivacaine
#1
Cristiane Neves Alessi Pissulin, Paula Aiello Tomé de Souza Castro, Flávio Codina, Carina Guidi Pinto, Ivan Jose Vechetti-Junior, Selma Maria Michelin Matheus
BACKGROUND: Local anesthetics are used to relieve pre- and postoperative pain, acting on both sodium channels and nicotinic acetylcholine receptors (nAChR) at the neuromuscular junction (NMJ). Bupivacaine acts as a non-competitive antagonist and has limitations, such as myotoxicity, neurotoxicity, and inflammation. Low-level laser therapy (LLLT) has anti-inflammatory, regenerative, and analgesic effects. The aim of the present study was to evaluate the effects of a gallium arsenide laser (GaAs) on the morphology of the NMJ and nAChRs after application of bupivacaine in the sternomastoid muscle...
December 22, 2016: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28078570/micro-rna-expression-in-muscle-and-fiber-morphometry-in-myotonic-dystrophy-type-1
#2
Chiara Fritegotto, Chiara Ferrati, Valentina Pegoraro, Corrado Angelini
We aimed to explore the cellular action of micro-RNAs that are non-coding-RNAs modulating gene expression, whose expression is dysregulated in myotonic dystrophy (DM1). Basic procedure was to measure the levels of muscle-specific myo-miRNAs (miR-1, miR-133a/b, miR-206) in muscle of 12 DM1 patients. Muscle fiber morphometry and a new grading of histopathological severity score were used to compare specific myo-miRNA level and fiber atrophy. We found that the levels of miR-1 and miR-133a/b were significantly decreased, while miR-206 was significantly increased as compared to controls...
January 11, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28078547/znf804a-rs1344706-interacts-with-comt-rs4680-to-affect-prefrontal-volume-in-healthy-adults
#3
Qiang Xu, Yongqin Xiong, Congcong Yuan, Feng Liu, Fangshi Zhao, Junlin Shen, Wen Qin, Chunshui Yu
The biological function of ZNF804A rs1344706, the first genome-wide supported risk variant of schizophrenia, remains largely unknown. Based on the upregulating effect of ZNF804A on the expression of COMT, we hypothesize that ZNF804A may affect grey matter volume (GMV) by interacting with COMT. Voxel-based morphometry was applied to analyze the main and interaction effects of ZNF804A rs1344706 and COMT rs4680 on brain GMV in 274 healthy young human subjects. The GMV of the left dorsolateral prefrontal cortex (DLPFC) showed a significant COMT rs4680 × ZNF804A rs1344706 interaction, manifesting as an inverted U-shape modulation by the presumed dopamine signaling...
January 11, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28077175/structural-correlates-of-trait-impulsivity-in-patients-with-bipolar-disorder-and-healthy-controls-a-surface-based-morphometry-study
#4
P C Tu, Y H Kuan, C T Li, T P Su
BACKGROUND: Patients with bipolar disorder (BD) frequently exhibit impulsive behaviors independent of their mood state, and trait impulsivity is increasingly recognized as a crucial BD biomarker. This study aimed to investigate structural correlates of trait impulsivity measured using the Barratt Impulsiveness Scale (BIS) in healthy controls (HCs) and patients with BD. METHOD: We recruited 59 patients diagnosed with BD I or BD II (35.3 ± 8.5 years) and 56 age- and sex-matched HCs (33...
January 12, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28076473/influence-of-tobacco-alcohol-and-diabetes-on-the-collagen-of-cremaster-muscle-in-patients-with-inguinal-hernias
#5
Sérgio Ferreira Módena, Eduardo José Caldeira, Marco Antonio O Peres, Nelson Adami Andreollo
Background: New findings point out that the mechanism of formation of the hernias can be related to the collagenous tissues, under activity of aggressive agents such as the tobacco, alcohol and diabetes. Aim: To analyze the collagen present in the cremaster muscle in patients with inguinal hernias, focusing the effect of tobacco, alcohol, and diabetes. Methods: Fifteen patients with inguinal hernia divided in three groups were studied: group I (n=5) was control; group II (n=5) were smokers and/or drinkers; and group III (n=5) had diabetes mellitus...
November 2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/28072384/impact-of-cerebellar-atrophy-on-cortical-gray-matter-and-cerebellar-peduncles-as-assessed-by-voxel-based-morphometry-and-high-angular-resolution-diffusion-imaging
#6
Michael Dayan, G Olivito, M Molinari, Mara Cercignani, Marco Bozzali, M Leggio
In recent years the cerebellum has been attributed amore important role in higher-level functions than previously believed. We examined a cohort of patients suffering from cerebellar atrophy resulting in ataxia, with two main objectives: first to investigate which regions of the cerebrum were affected by the cerebellar degeneration, and second to assess whether diffusion magnetic resonance imaging (dMRI) metrics within the medial (MCP) and superior cerebellar peduncle (SCP) - namely fractional anisotropy (FA) and radial diffusivity (RD) - could be used as a biomarker in patients with this condition...
October 2016: Functional Neurology
https://www.readbyqxmd.com/read/28070745/considering-total-intracranial-volume-and-other-nuisance-variables-in-brain-voxel-based-morphometry-in-idiopathic-pd
#7
Samuel Crowley, Haiqing Huang, Jared Tanner, Qing Zho, Nadine A Schwab, Loren Hizel, Daniel Ramon, Babette Brumback, Mingzhou Ding, Catherine C Price
Voxel-based morphometry (VBM) studies of Parkinson's disease (PD), have yielded mixed results, possibly due to several studies not accounting for common nuisance variables (age, sex, and total intracranial volume [TICV]). TICV is particularly important because there is evidence for larger TICV in PD. We explored the influence of these covariates on VBM by 1) comparing PD patients and controls before adding covariates, after adding age and sex, and after adding age, sex and TICV, and 2) by comparing controls split into large and small TICV before and after controlling for TICV, with age and sex accounted for in both analyses...
January 9, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28069530/structural-changes-in-functionally-illiterate-adults-after-intensive-training
#8
Melanie Boltzmann, Bahram Mohammadi, Amir Samii, Thomas F Münte, Jascha Rüsseler
About 7.5 million adults in Germany cannot read and write properly despite attending school for several years. They are considered to be functional illiterates. Since the ability to read and write is crucial for being employed and socially accepted, we developed a literacy training to overcome these deficits. In this study, we investigate the structural changes induced by the training. A group of 20 functional illiterates and 20 adult normal readers participated in the study. Group differences as well as intervention-related changes in gray (voxel-based morphometry, VBM) and white matter (tract-based spatial statistics, TBSS, applied to fractional anisotropy, FA, obtained with diffusion tensor imaging, DTI) were assessed in functional illiterates and normal reading controls...
January 6, 2017: Neuroscience
https://www.readbyqxmd.com/read/28069083/pcr-primers-for-straightforward-differentiation-of-haemonchus-contortus-haemonchus-placei-and-their-hybrids
#9
M R V Amarante, M C Santos, C C Bassetto, A F T Amarante
Haemonchus contortus and Haemonchus placei are among the major parasites of small ruminants and cattle. Although infection with these nematodes is host-specific, with H. placei predominating in cattle and H. contortus in sheep, cross-infections are observed in areas where both parasites are sympatric, and hybrid offspring can occur. Therefore, a fast and precise method is required for differentiating the parasites. Identification based on spicule morphometry is the most common technique for differentiating Haemonchus species...
January 10, 2017: Journal of Helminthology
https://www.readbyqxmd.com/read/28068398/correction-voxel-based-morphometry-in-individuals-at-genetic-high-risk-for-schizophrenia-and-patients-with-schizophrenia-during-their-first-episode-of-psychosis
#10
Miao Chang, Fay Y Womer, Chuan Bai, Qian Zhou, Shengnan Wei, Xiaowei Jiang, Haiyang Geng, Yifang Zhou, Yanqing Tang, Fei Wang
[This corrects the article DOI: 10.1371/journal.pone.0163749.].
2017: PloS One
https://www.readbyqxmd.com/read/28068068/reservoir-water-level-drawdowns-accelerate-and-amplify-methane-emission
#11
John A Harrison, Bridget R Deemer, M Keith Birchfield, Maria T O'Malley
Water-level fluctuations due to reservoir management could substantially affect the timing and magnitude of reservoir methane (CH4) fluxes to the atmosphere. However, effects of such fluctuations on CH4 emissions have received limited attention. Here we examine CH4 emission dynamics in six Pacific Northwest U.S. reservoirs of varying trophic status, morphometry, and management regimes. In these systems, we show that water-level drawdowns can, at least temporarily, greatly increase per-area reservoir CH4 fluxes to the atmosphere, and can account for more than 90% of annual reservoir CH4 flux in a period of just a few weeks...
January 9, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28066843/hyperbolic-space-sparse-coding-with-its-application-on-prediction-of-alzheimer-s-disease-in-mild-cognitive-impairment
#12
Jie Zhang, Jie Shi, Cynthia Stonnington, Qingyang Li, Boris A Gutman, Kewei Chen, Eric M Reiman, Richard J Caselli, Paul M Thompson, Jieping Ye, Yalin Wang
Mild Cognitive Impairment (MCI) is a transitional stage between normal age-related cognitive decline and Alzheimer's disease (AD). Here we introduce a hyperbolic space sparse coding method to predict impending decline of MCI patients to dementia using surface measures of ventricular enlargement. First, we compute diffeomorphic mappings between ventricular surfaces using a canonical hyperbolic parameter space with consistent boundary conditions and surface tensor-based morphometry is computed to measure local surface deformations...
October 2016: Medical Image Computing and Computer-assisted Intervention: MICCAI ..
https://www.readbyqxmd.com/read/28065824/variable-white-matter-atrophy-and-intellectual-development-in-a-family-with-x-linked-creatine-transporter-deficiency-despite-genotypic-homogeneity
#13
Nicole Heussinger, Marc Saake, Angelika Mennecke, Helmuth-Günther Dörr, Regina Trollmann
BACKGROUND: The X-linked creatine transporter deficiency (CRTD) caused by an SLC6A8 mutation represents the second most common cause of X-linked intellectual disability. The clinical phenotype ranges from mild to severe intellectual disability, epilepsy, short stature, poor language skills, and autism spectrum disorders. The objective of this study was to investigate phenotypic variability in the context of genotype, cerebral creatine concentration, and volumetric analysis in a family with CRTD...
October 17, 2016: Pediatric Neurology
https://www.readbyqxmd.com/read/28063247/replacing-corn-with-sorghum-in-the-diet%C3%A2-alters-intestinal-microbiota-without-altering-chicken-performance
#14
N S Fagundes, R Pereira, C Bortoluzzi, J M Rafael, G S Napty, J G M Barbosa, M C M Sciencia, J F M Menten
Sorghum grain can be used to replace corn in broiler diets. However, the effects related to an abrupt change between these grains are not yet clear. The aim of this study was to evaluate the performance and intestinal health of broilers fed diets containing corn and/or sorghum during different periods of rearing. To accomplish this aim, 2100 male chicks were fed the following experimental diets: C100% (corn-based diet); S100% (sorghum-based diet); C:S50% (diet based on corn and sorghum 1:1); PC-S (corn-based diet in the pre-starter phase and sorghum-based diet in subsequent phases); and PS-C (sorghum-based diet in the pre-starter phase and corn-based diet in subsequent phases)...
January 7, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28062991/complementary-description-of-ergasilus-arthrosis-roberts-1969-copepoda-poecilostomatoida-ergasilidae-a-new-parasite-of-cichlid-teleosts-in-southeast-mexico
#15
María Isabel Jiménez-García, Eduardo Suárez-Morales
During a parasitological survey of the ichthyofauna of Lake Catemaco, a freshwater system in the Mexican State of Veracruz, the widespread copepod Ergasilus arthrosis Roberts, 1969 was recovered from two cichlid teleosts, Mayaheros urophthalmus (Günther) and Oreochromis sp. This is the first confirmed record of this copepod species outside of the United States and from Mexico; its finding as a parasite of cichlids represents an expansion of the known host range for this copepod. The local prevalence and intensity of infection of E...
January 2017: Systematic Parasitology
https://www.readbyqxmd.com/read/28062990/ultrastructural-aspects-and-molecular-phylogeny-of-auerbachia-maamouni-n-sp-myxosporea-bivalvulida-from-the-gallbladder-of-gnathanodon-speciosus-forssk%C3%A3-l-actinopterygii-carangidae-in-the-red-sea
#16
Lamjed Mansour, Carlos Azevedo, Ângela Alves, Saleh Al-Quraishy, Abdel-Azeem S Abdel-Baki
A new myxosporean parasite, Auerbachia maamouni n. sp., infecting the gallbladder of the golden trevally Gnathanodon speciosus Forsskål, is described, based on morphology, ultrastructure, and small subunit (SSU) rRNA gene sequencing. Of 50 fish collected from the Red Sea in Jeddah, Saudi Arabia, five were found heavily infected with mature myxospores floating free in the bile. Mature spores are pyriform to club-shaped with smooth valves, and contain a single polar capsule with an S-shaped polar filament, arranged in 13-16 polar filament coils, oriented longitudinally, with an irregular distribution on the polar capsule matrix...
January 2017: Systematic Parasitology
https://www.readbyqxmd.com/read/28060546/gray-matter-hypertrophy-and-thickening-with-obstructive-sleep-apnea-in-middle-aged-and-older-adults
#17
Andrée-Ann Baril, Katia Gagnon, Pauline Brayet, Jacques Montplaisir, Louis De Beaumont, Julie Carrier, Chantal Lafond, Francis L'Heureux, Jean-François Gagnon, Nadia Gosselin
RATIONALE: Obstructive sleep apnea causes intermittent hypoxemia, hemodynamic fluctuations, and sleep fragmentation, all of which could damage cerebral gray matter that can be indirectly assessed with neuroimaging. OBJECTIVES: To investigate whether markers of obstructive sleep apnea severity are associated with gray matter changes among middle-aged and older individuals. METHODS: Seventy-one subjects (ages: 55 to 76; apnea-hypopnea index: 0...
January 6, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28057473/analysis-of-longitudinal-diffusion-weighted-images-in-healthy-and-pathological-aging-an-adni-study
#18
Frithjof Kruggel, Fumitaro Masaki, Ana Solodkin
BACKGROUND & NEW METHOD: The widely used framework of voxel-based morphometry for analyzing neuroimages is extended here to model longitudinal imaging data by exchanging the linear model with a linear mixed-effects model. The new approach is employed for analyzing a large longitudinal sample of 756 diffusion-weighted images acquired in 177 subjects of the Alzheimer's Disease Neuroimaging initiative (ADNI). RESULTS AND COMPARISON WITH EXISTING METHODS: While sample- and group-level results from both approaches are equivalent, the mixed-effect model yields information at the single subject level...
January 2, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28057431/advanced-structural-neuroimaging-in-progressive-supranuclear-palsy-where-do-we-stand
#19
REVIEW
Albert Stezin, Abhishek Lenka, Ketan Jhunjhunwala, Jitender Saini, Pramod K Pal
Progressive supranuclear palsy (PSP) is a progressive neurological disorder characterized by presence of supranuclear gaze palsy, early postural instability, parkinsonism and cognitive impairment. Advanced structural neuroimaging studies have demonstrated variable areas of grey and white matter involvement in PSP. Grey matter (GM) involvement is predominantly reported in the midbrain, subcortical structures such as thalamus and basal ganglia, and cerebellum. Most white matter (WM) tracts are also reported to be damaged in PSP...
December 26, 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28057397/neural-alterations-in-adhd-children-as-indicated-by-voxel-based-cortical-thickness-and-morphometry-analysis
#20
Uttam Kumar, Amit Arya, Vivek Agarwal
PURPOSE: Neuroimaging studies provide vital information related to the neurobiology of ADHD, but there still exists a wide gap in relevant information. The present study aimed to elucidate the neuroanatomical alteration in Attention deficit hyperactivity disorder (ADHD) children/adolescents. METHODS: Voxel-based cortical thickness (VBCT) and voxel-based morphometry (VBM) was performed to examine neuroanatomic distinctions in 18 children/adolescents aged 7.5-13years diagnosed with DSM-IV TR as ADHD (non-medicated)...
January 2, 2017: Brain & Development
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