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https://www.readbyqxmd.com/read/29691284/a-modified-algorithm-for-critical-congenital-heart-disease-screening-using-pulse-oximetry
#1
Christina L Diller, Michael S Kelleman, Kenneth G Kupke, Sharon C Quary, Lazaros K Kochilas, Matthew E Oster
: media-1vid110.1542/5727212367001PEDS-VA_2017-4065 Video Abstract OBJECTIVES: Determine the performance of the American Academy of Pediatrics (AAP) critical congenital heart disease (CCHD) newborn screening algorithm and the impact of an alternative algorithm. METHODS: Screening was performed on term infants without a known CCHD diagnosis at or near 24 hours of age at a tertiary birth hospital by using the AAP algorithm from 2013 to 2016. Retrospective review from the birth hospital and the area's sole pediatric cardiac center identified true- and false-positives and true- and false-negatives...
April 24, 2018: Pediatrics
https://www.readbyqxmd.com/read/29688648/-teaching-resuscitation-skills-on-a-newly-dead-infant
#2
Shaul Dollberg, Michael Y Barilan
Trainees in pediatrics and neonatology have to learn and remain updated regarding current lifesaving intubation procedures. The decrease in clinical indications for neonatal intubation limits their ability to practice and perfect procedures. Alternative methods for training, e.g., the use of manikins, do not satisfy the intended goal. Legitimization of the use of newly deceased infants for practice purposes is morally acceptable and may save lives. The requirement of mandatory parental consent for this type of training may result in reduced resuscitation capabilities and in loss of lives...
April 2018: Harefuah
https://www.readbyqxmd.com/read/29687659/effectiveness-and-safety-of-nasal-mask-versus-binasal-prongs-for-providing-continuous-positive-airway-pressure-in-preterm-infants-a-systematic-review-and-meta-analysis
#3
REVIEW
Bonny Jasani, Abu Ismail, Shripada Rao, Sanjay Patole
Continuous positive airway pressure (CPAP) delivered via binasal prongs has been the cornerstone of respiratory management in preterm infants. Though effective, the use of binasal prongs is associated with nasal trauma, and CPAP failure. To overcome these issues, nasal masks are increasingly used to deliver CPAP in preterm infants. The aim was to conduct a systematic review of randomized controlled trials (RCTs) comparing nasal mask versus binasal prongs to deliver CPAP in preterm infants. Medline, Embase, Cochrane Central Register of Controlled Trials, Cumulative Index of Nursing, and Allied Health Literature, and E-abstracts from the Pediatric Academic Society meetings were searched in May 2017...
April 23, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29685541/dual-source-computed-tomography-for-quantitative-assessment-of-tracheobronchial-anomaly-from-type-iia-pulmonary-artery-sling-in-pediatric-patients
#4
Ke Shi, Hong-Ling Gao, Zhi-Gang Yang, Hui-Jie Feng, Xi Liu, Ying-Kun Guo
PURPOSE: As an extremely rare abnormity, type IIA pulmonary artery sling (PAS) tracheobronchial anomalies should be differentiated from normal airway for therapeutic decision-making. This study aimed to investigate the quantitative characteristics of type IIA PAS tracheobronchial anomalies using dual-source computed tomography (DSCT). MATERIALS AND METHODS: From January 2009 to December 2016, there were 11 type IIA PAS patients enrolled for analysis and compared with 32 controls...
May 2018: European Journal of Radiology
https://www.readbyqxmd.com/read/29685491/initial-development-and-validation-of-a-fecal-incontinence-specific-quality-of-life-measure
#5
Christopher C Cushing, Melody R S Threlkeld, Bruno Martinez-Leo, Jennifer Hall, Monir Hossain, Belinda H Dickie, Beth Rymeski, Michael Helmrath, Meg H Zeller, Jason S Frischer
BACKGROUND/PURPOSE: Fecal incontinence is a prevalent pediatric condition with psychosocial impacts on both children and their caregivers. We sought to develop and validate the Cincinnati Fecal Incontinence Scale (CINCY-FIS) as a psychometrically valid measure to assess the quality of life and caregiver impacts of pediatric fecal incontinence. METHODS: Items were generated through review of previous measures, expert consensus, and pilot testing with feedback from 8 families...
March 7, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29685489/imaging-pediatric-gastrointestinal-stromal-tumor-gist
#6
REVIEW
Moriz Herzberg, Meinrad Beer, Sudha Anupindi, Kurt Vollert, Thomas Kröncke
BACKGROUND: Gastrointestinal stromal tumors (GIST) are extremely rare in children. Imaging plays a key role in staging and monitoring therapy (surgical and with tyrosine kinase inhibitors). The vast majority of articles addressing imaging of GIST base on adults and are based on CT. The subtype "pediatric GIST" - if at all - is only mentioned in a dependent clause. Although the imaging features in children and adults are similar, histology, clinical course and thus imaging approach are different...
March 29, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29683943/pentoxifylline-added-to-steroid-window-treatment-phase-modified-apoptotic-gene-expression-in-pediatric-patients-with-acute-lymphoblastic-leukemia
#7
Jesus Meza-Arroyo, Alejandro Bravo-Cuellar, Luis Felipe Jave-Suárez, Georgina Hernández-Flores, Pablo Ortiz-Lazareno, Adriana Aguilar-Lemarroy, Marlin Padilla-Corona, Fernando Sanchez-Zubieta, Oscar Gonzalez-Ramella
Pentoxifylline is a xanthine that possesses antitumor properties and that can induce higher apoptosis in the leukemic cells of pediatric patients with acute lymphoblastic leukemia (ALL) during treatment with prednisone. We conducted a phase 1 pilot, controlled, randomized trial to evaluate the gene expression modified by pentoxifylline during the steroid window of induction to remission phase in patients newly diagnosed with ALL. Experimental and control treatments induced broad changes in the gene expression profile...
April 20, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29681699/bronchoscopic-airway-foreign-body-extraction-without-using-optical-forceps
#8
Shalini Hegde, Umesh Bahadur, Ravi Prakash Kanojia, Monika Bawa, Ram Samujh
Aim: Airway foreign body (FB) is a very common pediatric surgical emergency. On certain difficult occasions, the extraction of FB with optical forceps (OFs) is difficult. These conditions create a life-threatening scenario. We present some of the alternative methods of FB extraction for these situations. Patients and Methods: This is a retrospective case review of patients presenting to pediatric emergency with airway FB. All patients had a chest X-ray done before the procedure...
April 2018: Journal of Indian Association of Pediatric Surgeons
https://www.readbyqxmd.com/read/29679413/prevalence-and-clinical-characteristics-of-chronic-spontaneous-urticaria-in-pediatric-patients
#9
Maria-Magdalena Balp, Karsten Weller, Veruska Carboni, Alexandra Chirilov, Charis Papavassilis, Thomas Severin, Haijun Tian, Torsten Zuberbier, Marcus Maurer
BACKGROUND: Data on the prevalence and disease management of chronic urticaria (CU) and chronic spontaneous urticaria (CSU) in the pediatric population are scarce. The present study assessed the prevalence of CU and CSU, and disease management among pediatric patients (0-17 years). METHODS: A physician-based online survey was conducted in 5 European countries (United Kingdom, Germany, Italy, France, and Spain) assessing the annual diagnosed prevalence, disease characteristics and treatment patterns in the target population...
April 21, 2018: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29678851/improved-diagnostic-and-prognostic-power-of-combined-delta-neutrophil-index-and-mean-platelet-volume-in-pediatric-sepsis
#10
Minjeong Nam, Byeong Hei Son, Jung Eun Seo, Il Ry Kim, Chee Kyoung Park, Hyun Kyung Kim
This study aims to evaluate the diagnostic and prognostic significance of white blood cell (WBC) and platelet parameters measured by automated hematology analyzers in pediatric sepsis. The study included 232 pediatric patients whose C-reactive protein test had been requested for evaluation of infection or inflammation at a pediatric tertiary hospital. The patients were allocated to control, systemic inflammatory response syndrome (SIRS) without infection, and sepsis groups. An ADVIA 2120i hematology system was used to measure the delta neutrophil index (DN) and platelet parameters including platelet count, mean platelet volume (MPV), platelet distribution width (PDW), plateletcrit (PCT), and immature platelet fraction (IPF)...
March 2018: Annals of Clinical and Laboratory Science
https://www.readbyqxmd.com/read/29676162/endoscopic-management-of-primary-obstructive-megaureter-a-systematic-review
#11
Alexander D Doudt, Chad R Pusateri, Matthew Christman
BACKGROUND: The gold standard treatment for primary obstructive megaureter (POM) with declining renal function, worsening obstruction, or recurrent infections is ureteral re-implantation with or without tapering. In infants, open surgery can be technically demanding and associated with significant morbidity. We conducted a systematic review of the literature with special interest in endoscopic management of POM and its outcomes. METHODS: A search was conducted of the MEDLINE/Ovid, PubMed, Embase, and Web of Science databases...
April 20, 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29676072/current-management-of-moderate-to-severe-atopic-dermatitis-a-survey-of-allergists-pediatric-allergists-and-dermatologists-in-korea
#12
Hye Yung Yum, Hyun Hee Kim, Hyun Jung Kim, Woo Kyung Kim, So Yeon Lee, Kapsok Li, Dong Hun Lee
PURPOSE: There is an unmet need for the treatment of moderate-to-severe atopic dermatitis (AD), leading to variation in management strategies. To investigate distinct features and treatment modalities according to physicians' specialties, we collected data on the current treatment approach to moderate-to-severe AD among allergists, pediatric allergists and dermatologists in Korea. METHODS: This questionnaire-based study was administered to physicians from the Korean Academy of Asthma, Allergy and Clinical Immunology (KAAACI), Korean Academy of Pediatric Allergy and Respiratory Disease (KAPARD), and Korean Atopic Dermatitis Association (KADA)...
May 2018: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/29675752/preliminary-report-on-endoscopic-pilonidal-sinus-treatment-in-children-results-of-a-multicentric-series
#13
Alessio Pini Prato, Cinzia Mazzola, Girolamo Mattioli, Maria Escolino, Ciro Esposito, Antonio D'Alessio, Laura Caterina Abati, Lorenzo Leonelli, Claudio Carlini, Franco Rotundi, Pier Carlo Meinero
BACKGROUND: Pilonidal disease is a troublesome acquired condition for whom various surgical treatments have been proposed with relatively high recurrence and complication rates. Since EPSiT technique has been described in 2013, it became an alternative treatment in adult practice. Our study reports the results of a multicentre series of pediatric patients who underwent EPSiT procedure over a 21-month period. METHODS: Between July 2015 and March 2017, all consecutive patients undergoing EPSiT in four different pediatric surgical units have been enrolled...
April 19, 2018: Pediatric Surgery International
https://www.readbyqxmd.com/read/29675402/poor-compliance-with-sepsis-guidelines-in-a-tertiary-care-children-s-hospital-emergency-room
#14
Benjamin Louis Moresco, Clinton Woosley, Morris Sauter, Utpal Bhalala
Objectives: This study aimed to assess factors related to adherence to the Pediatric Advanced Life Support guidelines for severe sepsis and septic shock in an emergency room (ER) of a tertiary care children's hospital. Methods: This was a retrospective, observational study of children (0-18 years old) in The Children's Hospital of San Antonio ER over 1 year with the International Consensus Definition Codes, version-9 (ICD-9) diagnostic codes for "severe sepsis" and "shocks...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29668479/mobile-application-neurogame-for-assessment-the-attention-focus-and-concentration
#15
Mario Loleski, Sofija Loleska, Nada Pop-Jordanova
Smartphones are ubiquitous, but it is still unknown what physiological functions can be monitored at clinical quality. In medicine their use is cited in many fields (cardiology, pulmology, endocrinology, rheumatology, pediatrics as well as in the field of mental health). The aim of this paper is to explain how the use of mobile application can help clients to improve the index of their focus, concentration and motor skills. Our original developed application on Android operating system, named "neurogame" is based on an open source platform to enable assessment and therapeutic stimulation, focus and concentration with the ability to monitor the progress of the results obtained in a larger number of participants (normal subjects as well as patients with different disorders) over a period of time...
December 1, 2017: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/29665442/carbapenems-versus-alternative-%C3%AE-lactams-for-the-treatment-of-nosocomial-pneumonia-a-systematic-review-and-meta-analysis
#16
J Nicholas O'Donnell, Nathaniel J Rhodes, Jenna Lopez, Rebecca Jett, Marc H Scheetz
BACKGROUND: Carbapenems have demonstrated efficacy in treating nosocomial pneumonias in clinical trials despite a reported low lung penetration compared to other β-lactams. Preserving the clinical activity of carbapenems through stewardship efforts is essential. This review aims to identify if differences in outcomes exist, potentially as a function of decreased penetration. METHODS: PubMed and Cochrane Library were systematically searched for clinical trials comparing carbapenems to other anti-pseudomonal β-lactams for the treatment of nosocomial pneumonia through December 2016...
April 14, 2018: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29664868/active-transcutaneous-bone-conduction-implant-middle-fossa-placement-technique-in-children-with-bilateral-microtia-and-external-auditory-canal-atresia
#17
Carolina Der, Sofía Bravo-Torres, Nicolás Pons
AIM: The aim of this study is to present the middle fossa technique (MFT) as an alternative for patients who cannot undergo traditional surgery for active transcutaneous bone conduction implants (ATBCI) due to their altered anatomy or desire for future aesthetic reconstruction. DESIGN: A case series descriptive study was designed. The MFT was developed. Preoperative and postoperative information from 24 patients with external auditory canal atresia (EACA) and implanted with ATBCI was reviewed...
April 16, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29664508/oral-self-mutilation-in-lesch-nyhan-syndrome-case-report
#18
Andrés Campolo González, Alex Vargas Díaz, Daniel Fontboté Riesco, Marta Hernández Chávez
INTRODUCTION: Lesch-Nyhan syndrome (LNS) is an inherited recessive X-related disorder caused by the deficiency of the enzyme hypoxanthin-guanine phosphorribosyl transferase (HPRT). Compul sive self-mutilation and dystonia occurs before the first year of age and is expressed by persistent bites on the oral mucosa, lips, tongue, fingers, and shoulders. The dental intervention performed on most of these patients is multiple tooth extraction to prevent serious secondary lesions. OBJECTIVE: To present a clinical case of LNS and describe pediatric dentistry management in patients with self-mutilating behavior...
February 2018: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/29660797/repair-of-a-giant-omphalocele-in-an-infant-with-a-pericardial-implant-crosslinked-with-oligourethane
#19
Juan Vargas-Mancilla, María A Torrero-Serrato, Aarón J Palacios-Rodríguez, Gloria B Rodríguez-de León, Metzeri I Montes-Rodríguez, Birzabith Mendoza-Novelo
The giant omphalocele (GO) represents a challenge for the pediatric surgeon in its management and wall abdominoplasty. Here, we report the outcome of a case in which a GO in a newborn patient was repaired with an implant derived from decellularized bovine pericardium crosslinked with oligourethane. The implantation time was extended for 6 months. This was then followed up by the retrieval of the implant and the subsequent reconstruction in a second surgical time by the closure of the abdominal wall fascia...
April 16, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29644453/analysis-of-factors-predicting-surgical-intervention-and-associated-costs-in-pediatric-breast-masses-a-single-center-study
#20
E Graham Englert, Guillermo Ares, Andrea Henricks, Karen Rychlik, Catherine J Hunter
PURPOSE: Finding a breast mass in a child provokes apprehension in parents, especially in those with a family history of breast cancer. Clinicians must decide between serial imaging or biopsy of the mass. Herein, we identify management differences in those with and without a positive family history, as well as identify cost differences. METHODS: An institutional retrospective review was performed of patients (2-18 years of age) with a diagnosis of breast mass...
April 11, 2018: Pediatric Surgery International
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