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https://www.readbyqxmd.com/read/29333096/analysis-of-med12-mutation-in-multiple-uterine-leiomyomas-in-south-korean-patients
#1
Minkyoung Lee, Keunyoung Cheon, Boah Chae, Hyesung Hwang, Hyun-Kyung Kim, Youn-Jee Chung, Jae-Yen Song, Hyun-Hee Cho, Jang-Heub Kim, Mee-Ran Kim
Uterine leiomyomas are one of the most common benign gynecologic tumors, but the exact causes are not completely understood. In 2011, through DNA sequencing, MED12 mutation was discovered in approximately 71% of uterine leiomyomas. Several recent studies confirmed the high frequency of MED12 mutation in uterine leiomyoma. Nevertheless, no study has been done on MED12 mutation in the case of patients with multiple leiomyomas in a patient. The purpose of this study was to investigate the frequency of MED12 mutations in uterine leiomyomas of South Korean patients...
2018: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/29320920/patency-of-uterine-wall-in-pregnancies-following-assisted-and-spontaneous-conception-with-antecedent-laparoscopic-and-abdominal-myomectomies-a-difficult-case-and-systematic-review
#2
Lucian Pop, Ioan Dumitru Suciu, Daniela Oprescu, Romeo Micu, Silvia Stoicescu, Ebrahim Forouqi, Peter Sipos
No abstract text is available yet for this article.
January 10, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29288921/outcome-of-magnetic-resonance-guided-focused-ultrasound-surgery-mrgfus-for-figo-class-1-fibroids
#3
Roy Mashiach, Yael Inbar, Jaron Rabinovici, Aya Mohr Sasson, Aviva Alagem-Mizrachi, Ronit Machtinger
OBJECTIVE: Intracavitary uterine fibroids and fibroids that distort the uterine cavity are associated with excessive vaginal bleeding and infertility. While intracavitary fibroids smaller than 4 cm are usually treated safely by operative hysteroscopy, larger fibroids may require multiple surgeries or more extensive surgery with possible damage to the integrity of the uterine wall. Magnetic resonance-guided focused ultrasound surgery (MRgFUS) is a noninvasive approach for treating uterine fibroids, mainly the intramural type...
December 14, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29285023/treating-symptomatic-uterine-fibroids-with-myomectomy-current-practice-and-views-of-uk-consultants
#4
R Mallick, F Odejinmi
No abstract text is available yet for this article.
2017: Gynecological Surgery
https://www.readbyqxmd.com/read/29275594/-comparison-of-early-clinical-effects-of-ablation-with-surgery-treatment-in-patients-with-hypertrophic-cardiomyopathy
#5
Y P Ruan, X W Liu, Y Zhang, J C Han, Y Q Lai, J Lü, Y H He
Objective: To compare the early clinical effect of septal myectomy and percutaneous transluminal septal myocardial ablation (PTMSA) on the left ventricular outflow obstruction and the rate of complication in patients with hypertrophic obstructive cardiomyopathy (HOCM). Methods: A total of 204 patients with HOCM who received septal reduction treatment were recruited. These patients were divided into two groups, surgery group (n=135) (65 patients with modified Morrow procedure, 70 patients with non-Morrow myomectomy) and PTMSA group (n=69)...
December 5, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29251677/indications-for-morcellation-in-gynecologic-surgery
#6
William H Parker
PURPOSE OF REVIEW: Minimally invasive gynecologic procedures, in particular laparoscopic hysterectomy and myomectomy, often require tissue morcellation. RECENT FINDINGS: Whether morcellated or not, myometrial cells can be found in the abdomen and pelvis after either laparoscopic or open myomectomy. Following morcellation, careful inspection for and removal of tissue fragments and copious irrigation and suctioning of fluid can remove residual tissue and cells without the use of containment bags...
February 2018: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29247353/structured-vs-narrative-reporting-of-pelvic-mri-for-fibroids-clarity-and-impact-on-treatment-planning
#7
Andrea Franconeri, Jieming Fang, Benjamin Carney, Almamoon Justaniah, Laura Miller, Hye-Chun Hur, Louise P King, Roa Alammari, Salomao Faintuch, Koenraad J Mortele, Olga R Brook
OBJECTIVES: To evaluate clarity and usefulness of MRI reporting of uterine fibroids using a structured disease-specific template vs. narrative reporting for planning of fibroid treatment by gynaecologists and interventional radiologists. METHODS: This is a HIPAA-compliant, IRB-approved study with waiver of informed consent. A structured reporting template for fibroid MRIs was developed in collaboration between gynaecologists, interventional and diagnostic radiologists...
December 15, 2017: European Radiology
https://www.readbyqxmd.com/read/29238287/survey-among-esge-members-on-leiomyosarcoma-morcellation-incidence
#8
Vasilios Tanos, Hans Brölmann, Rudi Leon DeWilde, Peter O'Donovan, Elina Symeonidou, Rudi Campo
Background: Increased awareness of leiomyosarcoma (LMS) risk during myomectomy or hysterectomy is essential. Objective and correct reasoning should prevail on any decision regarding the extent and type of surgery to employ. The anticipated risk of a sarcoma after myoma or uterus morcellation is low, and the frequency of leiomyosarcoma especially in women below the age of 40 is very rare. The prevalence data has a wide range and is therefore not reliable. The European Society of Gynaecological Endoscopy (ESGE) initiated a survey among its members looking into the frequency of morcellated leiomyosarcoma after endoscopic surgery...
2017: Gynecological Surgery
https://www.readbyqxmd.com/read/29227976/progesterone-receptor-isoforms-nuclear-corepressor-1-and-steroid-receptor-coactivator-1-and-b-cell-lymphoma-2-and-akt-and-akt-phosphorylation-status-in-uterine-myomas-after-ulipristal-acetate-treatment-a-systematic-immunohistochemical-evaluation
#9
Guillaume E Courtoy, Jacques Donnez, Etienne Marbaix, Matilde Barreira, Mathieu Luyckx, Marie-Madeleine Dolmans
OBJECTIVE: To investigate whether ulipristal acetate (UPA) treatment modifies the expression of progesterone receptor (PR), its nuclear cofactors steroid receptor coactivator-1 (SRC1) and nuclear corepressor-1 (NCoR1), prosurvival factor B-cell lymphoma 2 (Bcl-2), and Akt in uterine myomas. PATIENTS: Prospective study of 59 women with symptomatic myomas undergoing myomectomy. Forty-two patients were treated preoperatively with UPA; the remaining 17 were not and they served as controls...
December 11, 2017: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/29227848/development-and-evaluation-of-an-improved-laparoscopic-myomectomy-adopting-intracapsular-rotary-cut-procedures
#10
Shi-Lin Zhong, Li-Ping Zeng, Huan Li, Rui-Fang Wu
OBJECTIVES: To develop and evaluate the efficacy and feasibility of Intracapsular Rotary-cut Procedure (IRCP) in laparoscopic myomectomy (LM). STUDY DESIGN: It is a retrospective study conducted in Peking University Shenzhen Hospital (PUSH) in Shenzhen, China. A total of 96 patients who were treated with LM because of big and moderate size of myomas in PUSH from January 2013 and December 2015 were enrolled in this study. Among them 35 were managed with IRCP -integrated LM as the study group, while the other 61 were treated with normal LM as the control group...
November 27, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29227004/recurrence-of-uterine-myoma-after-myomectomy-open-myomectomy-versus-laparoscopic-myomectomy
#11
Yasushi Kotani, Takako Tobiume, Risa Fujishima, Mamoru Shigeta, Hisamitsu Takaya, Hidekatsu Nakai, Ayako Suzuki, Isao Tsuji, Masaki Mandai, Noriomi Matsumura
AIM: Open myomectomy (OM) was previously frequently performed; however, laparoscopic myomectomy (LM) has recently become more common. Nevertheless, myoma can recur after both LM and OM. In this study, we report our retrospective investigation of myoma recurrence by comparing LM and OM. METHODS: A total of 474 patients underwent LM and 279 patients underwent OM. The patients were followed-up postoperatively from six months to eight years. Recurrence was confirmed when a myoma with a diameter of ≥ 1 cm was detected...
December 11, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29215821/a-fast-3-dimensional-magnetic-resonance-imaging-reconstruction-for-surgical-planning-of-uterine-myomectomy
#12
Sa Ra Lee, Young Jae Kim, Kwang Gi Kim
BACKGROUND: Uterine myoma is the most common benign gynecologic tumor in reproductive-aged women. During myomectomy for women who want to preserve fertility, it is advisable to detect and remove all myomas to decrease the risk of additional surgery. However, finding myomas during surgery is often challenging, especially for deep-seated myomas. Therefore, three-dimensional (3D) preoperative localization of myomas can be helpful for the surgical planning for myomectomy. However, the previously reported manual 3D segmenting method takes too much time and effort for clinical use...
January 8, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29207370/a-bleeding-heart-coronary-cameral-fistula-after-septal-myomectomy
#13
Daniel Walters, Ryan Reeves, Lawrence Ang, Ali Pourdjabbar, Ehtisham Mahmud
Coronary-cameral fistulas are relatively rare communications arising within the coronary vasculature entering into one of the four cardiac chambers. This case highlights a striking angiographic example of coronary-cameral fistula occurring after septal myomectomy, a complication occurring somewhat frequently with typical spontaneous resolution.
December 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29207362/alcohol-septal-ablation-for-hypertrophic-obstructive-cardiomyopathy-indications-technical-aspects-and-clinical-outcomes
#14
REVIEW
Marco Spaziano, Fadi J Sawaya, Thierry Lefèvre
Hypertrophic cardiomyopathy is the most common genetically transmitted heart disease. Around two-thirds of patients develop symptoms caused by the dynamic left ventricular outflow tract obstruction, either at rest or during effort. For patients with hypertrophic obstructive cardiomyopathy (HOCM) that remain symptomatic despite optimal medical treatment, septal reduction is a valuable therapeutic strategy. While surgical myomectomy was considered the gold standard until the end of the 1990s, alcohol septal ablation (ASA) has gained rapid popularity and acceptance, especially in Europe...
December 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29200989/pushing-the-boundaries-of-laparoscopic-myomectomy-a-comparative-analysis-of-peri-operative-outcomes-in-323-women-undergoing-laparoscopic-myomectomy-in-a-tertiary-referral-centre
#15
Rebecca Mallick, Funlayo Odejinmi
Background: The aim of this study was to analyse the demographic data and peri-operative outcomes of women undergoing a laparoscopic myomectomy and assess what factors, if any, precluded using the laparoscopic approach. Methods: A single surgeon observational study of 323 patients undergoing a laparoscopic myomectomy was undertaken. Data was collected prospectively over a 12-year period and analysed using SPSS. Surgical outcomes included operating time, estimated blood loss, conversion to laparotomy, intraoperative and postoperative complications and duration of inpatient stay...
2017: Gynecological Surgery
https://www.readbyqxmd.com/read/29200476/outcome-of-cesarean-myomectomy-is-it-a-safe-procedure
#16
Mehmet Baki Senturk, Mesut Polat, Ozan Doğan, Çiğdem Pulatoğlu, Oğuz Devrim Yardımcı, Resul Karakuş, Ahter Tanay Tayyar
Objective: Myomectomy performed during cesarean section is still controversial because of the potential for associated complications, especially with large myomas. Many obstetricians avoid performing cesarean myomectomy procedures because of the risk of uncontrollable hemorrhage. However, the prevalence of pregnant women with myomas is increasing, leading to an increase in the likelihood that physicians will encounter this issue. The aim of this study was to compare outcomes and complications of patients who either had or did not have cesarean myomectomy...
November 2017: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/29181211/placenta-percreta-in-first-trimester-after-multiple-rounds-of-failed-medical-management-for-a-missed-abortion
#17
Jaimin Shah, Eduardo Matta, Fernando Acosta, Natalia Golardi, Cristina Wallace-Huff
Background: The detection of a morbidly adherent placenta (MAP) in the first trimester is rare. Risk factors such as multiparity, advanced maternal age, prior cesarean delivery, prior myomectomy, placenta previa, or previous uterine evacuation place patients at a higher risk for having abnormal placental implantation. If these patients have a first trimester missed abortion and fail medical management, it is important that providers have a heightened suspicion for a MAP. Case: A 24-year-old G4P3003 with 3 prior cesarean deliveries underwent multiple rounds of failed medical management for a missed abortion...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29180306/the-intraoperative-effect-of-preoperative-gnrh-analogue-administration-in-women-undergoing-cold-loop-hysteroscopic-myomectomy-a-randomized-controlled-trial
#18
Alessandro Favilli, Ivan Mazzon, Mario Grasso, Stefano Horvath, Vittorio Bini, Gian Carlo Di Renzo, Sandro Gerli
STUDY OBJECTIVE: To evaluate the intraoperative effects of GnRH analogue pretreatment in patients undergoing cold loop hysteroscopic myomectomy. DESIGN: Randomized controlled trial (Canadian Task Force Classification I). SETTING: Arbor Vitae Center for Endoscopic Gynecology, Rome, Italy. PATIENTS: A total of 99 patients were randomized and subsequently allocated to the GnRH analogue group and to the non-pharmacological treatment control group...
November 24, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29177589/ultrasound-guided-core-needle-biopsy-prior-to-thermo-ablative-treatment-of-uterine-tumors-first-results
#19
Christina B Walter, Andreas D Hartkopf, Dorit Schoeller, Bernhard Kraemer, Felix Neis, Florin-Andrei Taran, Keith B Isaacson, Sara Y Brucker, Markus Hahn
PURPOSE: This study aimed at evaluating the diagnostic yield for core needle biopsies of uterine fibroids before laparoscopic radiofrequency volumetric thermal ablation (RFVTA) with the aim of sonographic imaging. This study was in the context of a randomized, prospective, single-center, longitudinal comparative study in which RFVTA and laparoscopic myomectomy for symptomatic uterine fibroids were compared. METHODS: All patients of the RFVTA-arm received a core needle biopsy under the guidance of an intraoperative laparoscopic ultrasound system...
November 24, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29169896/the-current-place-of-medical-therapy-in-uterine-fibroid-management
#20
REVIEW
Jacques Donnez, Olivier Donnez, Marie-Madeleine Dolmans
Uterine fibroids (also known as leiomyomas or myomas) are the most common form of benign uterine tumors. Current management strategies mainly involve surgical interventions, but the choice of treatment is guided by patient's age and desire to preserve fertility or avoid "radical" surgery. Surgical and non-surgical approaches include hysterectomy myomectomy by hysteroscopy, myomectomy by laparotomy or laparoscopy, uterine artery embolization, and magnetic resonance-guided focused ultrasound surgery. The need for alternatives to surgical intervention is very real, especially for women seeking to preserve their fertility...
October 22, 2017: Best Practice & Research. Clinical Obstetrics & Gynaecology
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