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https://www.readbyqxmd.com/read/27797801/weston-hurst-syndrome-a-rare-fulminant-form-of-acute-disseminated-encephalomyelitis-adem
#1
Sumaira Nabi, Mazhar Badshah, Shahzad Ahmed, Ali Zohair Nomani
A 25-year-old Pakistani woman presented to the emergency department with a 2-day history of rapidly progressive tetraplegia followed by sudden loss of consciousness. This was preceded by an upper respiratory tract infection. On examination, she was deeply comatose with a GCS of 3/15 and intact brainstem reflexes. She was in respiratory distress, and an endotracheal tube had been passed. She had flaccid quadriplegia with depressed deep tendon reflexes and upgoing plantar response. Her MRI brain with contrast showed extensive brainstem involvement with haemorrhagic foci along with signal changes in the corpus callosum...
October 19, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27708585/comparative-analysis-of-the-equivital-eq02-lifemonitor-with-holter-ambulatory-ecg-device-for-continuous-measurement-of-ecg-heart-rate-and-heart-rate-variability-a-validation-study-for-precision-and-accuracy
#2
Abimbola A Akintola, Vera van de Pol, Daniel Bimmel, Arie C Maan, Diana van Heemst
Background: The Equivital (EQ02) is a multi-parameter telemetric device offering both real-time and/or retrospective, synchronized monitoring of ECG, HR, and HRV, respiration, activity, and temperature. Unlike the Holter, which is the gold standard for continuous ECG measurement, EQO2 continuously monitors ECG via electrodes interwoven in the textile of a wearable belt. Objective: To compare EQ02 with the Holter for continuous home measurement of ECG, heart rate (HR), and heart rate variability (HRV). Methods: Eighteen healthy participants wore, simultaneously for 24 h, the Holter and EQ02 monitors...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27626633/unconstrained-sleep-stage-estimation-based-on-respiratory-dynamics-and-body-movement
#3
Su H Hwang, Yu J Lee, Do U Jeong, Kwang S Park
OBJECTIVES: The aim of this study is to establish a sleep monitoring method that can classify sleep into four stages in an unconstrained manner using a polyvinylidene fluoride (PVDF) sensor for continuous and accurate estimation of sleep stages. METHODS: The study participants consisted of 12 normal subjects and 13 obstructive sleep apnea (OSA) patients. The physiological signals of the subjects were unconstrainedly measured using the PVDF sensor during polysomnography...
September 14, 2016: Methods of Information in Medicine
https://www.readbyqxmd.com/read/27598922/-weannet-the-network-of-weaning-units-of-the-dgp-deutsche-gesellschaft-f%C3%A3-r-pneumologie-und-beatmungsmedizin-results-to-epidemiology-an-outcome-in-patients-with-prolonged-weaning
#4
(no author information available yet)
BACKGROUND: In 40 % of all ventilated patients weaning is problematic. Prolonged weaning is associated with an increased mortality. METHODS: For the first time, data on epidemiology and outcomes of 6899 patients with prolonged weaning from the WeanNet register are published in this study. RESULTS: Patients with prolonged weaning suffer from profound comorbidities (median 5 relevant comorbidities). The majority of patients (62.2 %) were successfully weaned from the ventilator and dischared from the weaning unit without invasive ventialtion after a median of 33 days...
September 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27440136/dust-library-of-plasmonically-enhanced-infrared-spectra-of-individual-respirable-particles
#5
Antriksh Luthra, Aruna Ravi, Sirui Li, Steven V Nystrom, Zechariah Thompson, James V Coe
This work characterizes collections of infrared spectra of individual dust particles of ∼4 µm size that were obtained from three very different environments: our lab air, a home air filter, and the 11 September 2001 World Trade Center event. Particle collection was done either directly from the air or by placing dust powder from various samples directly on the plasmonic mesh with 5 µm square holes as air is pumped through the mesh. This arrangement enables the recording of "scatter-free" infrared absorption spectra of individual particles of size comparable to the probing wavelengths whose vibrational signatures are otherwise dominated by scattering and dispersive line shape distortions...
September 2016: Applied Spectroscopy
https://www.readbyqxmd.com/read/27401086/creatine-transporter-deficiency-leads-to-increased-whole-body-and-cellular-metabolism
#6
Marla K Perna, Amanda N Kokenge, Keila N Miles, Kenea C Udobi, Joseph F Clark, Gail J Pyne-Geithman, Zaza Khuchua, Matthew R Skelton
Creatine (Cr) is a guanidino compound required for rapid replenishment of ATP in cells with a high-energy demand. In humans, mutations in the Cr transporter (CRT;SLC6A8) prevent Cr entry into tissue and result in a significant intellectual impairment, epilepsy, and aphasia. The lack of Cr on both the whole body and cellular metabolism was evaluated in Crt knockout (Crt (-/y) ) mice, a high-fidelity model of human CRT deficiency. Crt (-/y) mice have reduced body mass and, however, show a twofold increase in body fat...
August 2016: Amino Acids
https://www.readbyqxmd.com/read/27397661/effectiveness-of-oral-appliances-in-obstructive-sleep-apnea-with-respiratory-arousals
#7
Pia Nerfeldt, Danielle Friberg
STUDY OBJECTIVES: To compare adherence and treatment effects with an oral appliance (OA) in patients with different types of obstructive sleep apnea (OSA): those with mainly respiratory arousals ("arousers"), and those with oxygen desaturations ("desaturaters") at polysomnography (PSG). METHODS: A prospective intervention study on 72 "tired snorers" with "normal" home sleep study (HSS), but later diagnosed as OSA with PSG, who accepted OA treatment. They were offered evaluation with a follow-up PSG and questionnaires, including the Epworth Sleepiness Scale (ESS), general health (GH), satisfaction, and side effects...
2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/27327257/nucleus-accumbens-deep-brain-stimulation-efficacy-in-acth-pretreated-rats-alterations-in-mitochondrial-function-relate-to-antidepressant-like-effects
#8
Y Kim, S McGee, J K Czeczor, A J Walker, R P Kale, A Z Kouzani, K Walder, M Berk, S J Tye
Mitochondrial dysfunction has a critical role in the pathophysiology of mood disorders and treatment response. To investigate this, we established an animal model exhibiting a state of antidepressant treatment resistance in male Wistar rats using 21 days of adrenocorticotropic hormone (ACTH) administration (100 μg per day). First, the effect of ACTH treatment on the efficacy of imipramine (10 mg kg(-1)) was investigated alongside its effect on the prefrontal cortex (PFC) mitochondrial function. Second, we examined the mood-regulatory actions of chronic (7 day) high-frequency nucleus accumbens (NAc) deep-brain stimulation (DBS; 130 Hz, 100 μA, 90 μS) and concomitant PFC mitochondrial function...
2016: Translational Psychiatry
https://www.readbyqxmd.com/read/27067482/sdf-1-cxcl12-modulates-mitochondrial-respiration-of-immature-blood-cells-in-a-bi-phasic-manner
#9
Steven Messina-Graham, Hal Broxmeyer
SDF-1/CXCL12 is a potent chemokine required for the homing and engraftment of hematopoietic stem and progenitor cells. Previous data from our group has shown that in an SDF-1/CXCL12 transgenic mouse model, lineage(-) Sca-1(+) c-Kit(+) (LSK) bone marrow cells have reduced mitochondrial membrane potential versus wild-type. These results suggested that SDF-1/CXCL12 may function to keep mitochondrial respiration low in immature blood cells in the bone marrow. Low mitochondrial metabolism helps to maintain low levels of reactive oxygen species (ROS), which can influence differentiation...
May 2016: Blood Cells, Molecules & Diseases
https://www.readbyqxmd.com/read/26967045/measuring-cardiac-autonomic-nervous-system-ans-activity-in-toddlers-resting-and-developmental-challenges
#10
Nicole R Bush, Zoe K Caron, Katherine S Blackburn, Abbey Alkon
The autonomic nervous system (ANS) consists of two branches, the parasympathetic and sympathetic nervous systems, and controls the function of internal organs (e.g., heart rate, respiration, digestion) and responds to everyday and adverse experiences (1). ANS measures in children have been found to be related to behavior problems, emotion regulation, and health (2-7). Therefore, understanding the factors that affect ANS development during early childhood is important. Both branches of the ANS affect young children's cardiovascular responses to stimuli and have been measured noninvasively, via external monitoring equipment, using valid and reliable measures of physiological change (8-11)...
2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/26847975/sleep-quality-changes-in-chronically-depressed-patients-treated-with-mindfulness-based-cognitive-therapy-or-the-cognitive-behavioral-analysis-system-of-psychotherapy-a-pilot-study
#11
Preetam J Schramm, Ingo Zobel, Kathrin Mönch, Elisabeth Schramm, Johannes Michalak
OBJECTIVE: To capture any sleep quality changes associated with group psychotherapy. PATIENTS/METHODS: Physician-referred, chronically depressed patients (n = 25) were randomized to either eight group sessions of Mindfulness-based Cognitive Therapy (MBCT, n = 9) plus Treatment As Usual (TAU), or the Cognitive Behavioral Analysis System of Psychotherapy (CBASP, n = 8) plus TAU, or to TAU only (control group, n = 8). Participants recorded their sleep at home...
January 2016: Sleep Medicine
https://www.readbyqxmd.com/read/26797725/mechanistic-pathways-of-mindfulness-meditation-in-combat-veterans-with-posttraumatic-stress-disorder
#12
Helané Wahbeh, Elena Goodrich, Elizabeth Goy, Barry S Oken
OBJECTIVE: This study's objective was to evaluate the effect of two common components of meditation (mindfulness and slow breathing) on potential mechanistic pathways. METHODS: A total of 102 combat veterans with posttraumatic stress disorder (PTSD) were randomized to (a) the body scan mindfulness meditation (MM), (b) slow breathing (SB) with a biofeedback device, (c) mindful awareness of the breath with an intention to slow the breath (MM+SB), or (d) sitting quietly (SQ)...
April 2016: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/26775187/inhalation-a-significant-exposure-route-for-chlorinated-organophosphate-flame-retardants
#13
Erika D Schreder, Nancy Uding, Mark J La Guardia
Chlorinated organophosphate flame retardants (ClOPFRs) are widely used as additive flame retardants in consumer products including furniture, children's products, building materials, and textiles. Tests of indoor media in homes, offices, and other environments have shown these compounds are released from products and have become ubiquitous indoor pollutants. In house dust samples from Washington State, U.S.A., ClOPFRs were the flame retardants detected in the highest concentrations. Two ClOPFRs, tris(1,3-dichloro-2-propyl)phosphate (TDCPP or TDCIPP) and tris(2-chloroethyl)phosphate (TCEP), have been designated as carcinogens, and there is growing concern about the toxicity of the homologue tris(1-chloro-2-propyl)phosphate (TCPP or TCIPP)...
May 2016: Chemosphere
https://www.readbyqxmd.com/read/26710646/-responses-of-soil-microbial-carbolic-metabolism-characteristics-to-home-field-advantage-of-leaf-litter-decomposition-in-liaoheyuan-nature-reserve-of-northern-hebei-province-china
#14
Tian-yu Li, Feng-feng Kang, Hai-rong Han, Jing Gao, Xiao-shuai Song, Shu Yu
Using litter bag method, we studied the responses of soil microbial biomass carbon (MBC), microbial respiration (MR) and microbial metabolic quotient (qCO2) in 0-5 cm, 5-10 cm and 10-20 cm soil layers to home-field advantage of Betula platyphlla and Quercus mongolica leaf litter decomposition in Liaoheyuan Nature Reserve, northern Hebei Province. The results showed that the contents of MBC in Betula platyphila and Quercus mongolica leaf litter treatments in home environment (Bh and Qh treatments) were significant higher than that in B...
July 2015: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
https://www.readbyqxmd.com/read/26686520/the-18th-collegium-ramazzini-statement-the-global-health-dimensions-of-asbestos-and-asbestos-related-diseases
#15
(no author information available yet)
The Collegium Ramazzini reaffirms its long-standing position that responsible public health action is to ban all extraction and use of asbestos, including chrysotile. This current statement updates the Collegium's earlier statements with a focus on global health dimensions of asbestos and asbestos-related diseases (ARD). The ARD epidemic will likely not peak for at least a decade in most industrialized countries and for several decades in industrializing countries. Asbestos and ARD will continue to present challenges in the arena of occupational medicine and public health, as well as in clinical research and practice, and have thus emerged as a global health issue...
January 2016: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/26640970/video-based-respiration-monitoring-with-automatic-region-of-interest-detection
#16
Rik Janssen, Wenjin Wang, Andreia Moço, Gerard de Haan
Vital signs monitoring is ubiquitous in clinical environments and emerging in home-based healthcare applications. Still, since current monitoring methods require uncomfortable sensors, respiration rate remains the least measured vital sign. In this paper, we propose a video-based respiration monitoring method that automatically detects a respiratory region of interest (RoI) and signal using a camera. Based on the observation that respiration induced chest/abdomen motion is an independent motion system in a video, our basic idea is to exploit the intrinsic properties of respiration to find the respiratory RoI and extract the respiratory signal via motion factorization...
January 2016: Physiological Measurement
https://www.readbyqxmd.com/read/26632086/analysis-of-respiratory-events-in-obstructive-sleep-apnea-syndrome-inter-relations-and-association-to-simple-nocturnal-features
#17
H Ghandeharioun, F Rezaeitalab, R Lotfi
OBJECTIVE: This study carefully evaluates the association of different respiration-related events to each other and to simple nocturnal features in obstructive sleep apnea-hypopnea syndrome (OSAS). The events include apneas, hypopneas, respiratory event-related arousals and snores. METHODS: We conducted a statistical study on 158 adults who underwent polysomnography between July 2012 and May 2014. To monitor relevance, along with linear statistical strategies like analysis of variance and bootstrapping a correlation coefficient standard error, the non-linear method of mutual information is also applied to illuminate vague results of linear techniques...
March 2016: Revista Portuguesa de Pneumologia
https://www.readbyqxmd.com/read/26571292/the-effect-of-waterbirth-on-neonatal-mortality-and-morbidity-a-systematic-review-and-meta-analysis
#18
Rowena Davies, Deborah Davis, Melissa Pearce, Nola Wong
BACKGROUND: Women have been giving birth in water in many centers across the globe; however, the practice remains controversial. Qualitative studies highlight the benefits that waterbirth confers on the laboring woman, though due to the nature of the intervention, it is not surprising that there are few randomized controlled trials available to inform practice. Much of the criticism directed at waterbirth focuses on the potential impact on the neonate. OBJECTIVES: The objective of this review was to systematically synthesize the best available evidence regarding the effect of waterbirth, compared to landbirth, on the mortality and morbidity of neonates born to low risk women...
October 2015: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/26524776/-design-and-application-of-portable-micro-sleep-monitoring-system
#19
Jilun Ye, Fengling Du, Xu Zhang, Siping Chen, Tianfu Wang
Through the study of the pathology of sleep apnea-hypopnea syndrome, evaluation indexes, diagnosis requirements and so on, a portable sleep monitoring system was designed, which had the characteristics of convenience, wireless transmission and no disturbance. The system can be assessed by respiration monitoring and pulse oximetry, which is based on the pressure variation in miniature air-bag and spectral absorption method. It provides the value of the apnea-hypopnea index (AHI), which is used to evaluate OSAHS severity...
March 2015: Zhongguo Yi Liao Qi Xie za Zhi, Chinese Journal of Medical Instrumentation
https://www.readbyqxmd.com/read/26479338/multi-modal-signal-acquisition-using-a-synchronized-wireless-body-sensor-network-in-geriatric-patients
#20
Maik Pflugradt, Steffen Mann, Timo Tigges, Matthias Görnig, Reinhold Orglmeister
Wearable home-monitoring devices acquiring various biosignals such as the electrocardiogram, photoplethysmogram, electromyogram, respirational activity and movements have become popular in many fields of research, medical diagnostics and commercial applications. Especially ambulatory settings introduce still unsolved challenges to the development of sensor hardware and smart signal processing approaches. This work gives a detailed insight into a novel wireless body sensor network and addresses critical aspects such as signal quality, synchronicity among multiple devices as well as the system's overall capabilities and limitations in cardiovascular monitoring...
February 2016: Biomedizinische Technik. Biomedical Engineering
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