keyword
https://read.qxmd.com/read/37995016/low-flow-perfusion-technique-for-shaggy-aortic-arch
#21
JOURNAL ARTICLE
Takashi Shuto, Hirofumi Anai, Tomoyuki Wada, Takayuki Kawashima, Kazuki Mori, Shinji Miyamoto
BACKGROUND: The most common complication of thoracic aortic disease with shaggy aorta is cerebral infarction. We have performed "low-flow perfusion" as a method of extracorporeal circulation to prevent cerebral embolism in patients with strong atherosclerotic lesions in the aortic arch. METHODS: "Low-flow perfusion" is a method in which cardiopulmonary bypass is started by partial blood removal, approaching deep hypothermia while maintaining self-cardiac output...
November 23, 2023: General Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/37964285/simultaneous-upper-and-lower-body-perfusion-using-hypothermia-during-thoracoabdominal-aortic-surgery
#22
JOURNAL ARTICLE
Yuya Kise, Yukio Kuniyoshi, Mizuki Ando, Keita Miyaishi, Shotaro Higa, Tatuya Maeda, Moriyasu Nakaema, Hitoshi Inafuku, Kojiro Furukawa
BACKGROUND: In open thoracoabdominal aortic aneurysm (TAAA) repair, we have been performing vascular reconstruction under moderate to deep hypothermia and assisted circulation using simultaneous upper and lower body perfusion. This method is effective for protecting the spinal cord and the brain, heart, and abdominal organs and for avoiding lung damage. METHODS: TAAA repair was performed under hypothermia at 20-28 °C in 18 cases (Crawford type I in 0 cases, type II in 5, type III in 3, type IV in 4, and Safi V in 6) between October 2014 and January 2023...
November 14, 2023: Journal of Cardiothoracic Surgery
https://read.qxmd.com/read/37946246/a-modified-chain-based-sponge-dressing-controls-junctional-hemorrhage-in-the-tactical-combat-casualty-care-simulation-of-pigs
#23
JOURNAL ARTICLE
Weihang Wu, Wangwu Liu, Nan Lin, Hu Zhao, Jin Yang, Zhi Ye, Weijin Yang, Yu Wang, Yongchao Fang
BACKGROUND: Hemorrhage has always been the focus of battlefield and pre-hospitalization treatment. With the increasing fatality rates associated with junctional bleeding, treatment of bleeding at junctional sites has gradually gained attention in battlefield trauma emergency care. We designed a modified chain-based sponge dressing with a medical polyvinyl alcohol sponge that can be used to treat junctional hemorrhage and tested its hemostatic efficacy and biocompatibility. METHODS: Twenty adult Bama miniature pigs were randomly divided into the modified chain-based sponge dressing (MCSD) and standard gauze (SG) groups...
November 9, 2023: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://read.qxmd.com/read/37945074/lipoplasty-in-the-overweight-patient
#24
REVIEW
Emmanuel De La Cruz
The practice of large volume liposuction, when executed by board-certified plastic surgeons using a variety of energy-assisted liposuction devices, has been substantiated as a secure procedure, yielding enhanced aesthetic results and minimal complications. Techniques including the superwet technique and ultrasonic-assisted liposuction are utilized to diminish blood loss, while also maintaining a keen awareness of the maximum volume of infiltration fluid permissible for safe infusion. Adherence to evidence-based protocols is of paramount importance to reduce the risk of postoperative complications...
January 2024: Clinics in Plastic Surgery
https://read.qxmd.com/read/37944009/pioneer-of-cardiothoracic-surgery-luiz-tavares-da-silva
#25
JOURNAL ARTICLE
Ricardo de Carvalho Lima, Leonardo Pontual Lima, Mozart Augusto Soares de Escobar, José Ricardo Lagreca de Sales Cabral, José Aécio Fernandes Vieira, Guilherme Tavares da Silva Maia
Luis Tavares revolutionized cardiac surgery, always bringing the most modern instruments and equipment from his travels to England - surgical forceps, scissors, scalpels, etc. He always insisted that he was not just a thoracic surgeon, for his work extended over a wide field and created three important cardiac surgery centers which promoted a great development of cardiology. He carried out the first open heart surgery (atrial septal defect) employing extracorporeal circulation and closure of a ventricular septal defect with deep surface hypothermia of north and northeast Brazil...
November 9, 2023: Brazilian Journal of Cardiovascular Surgery
https://read.qxmd.com/read/37906983/brain-injury-outcomes-after-adjuvant-erythropoietin-neuroprotection-for-moderate-or-severe-neonatal-hypoxic-ischemic-encephalopathy-a-report-from-the-heal-trial
#26
JOURNAL ARTICLE
Jessica L Wisnowski, Sarah E Monsell, Stefan Bluml, Amy M Goodman, Yi Li, Bryan Comstock, Patrick Heagerty, Sandra E Juul, Yvonne W Wu, Robert C McKinstry, Amit Mathur
INTRODUCTION: Erythropoietin (Epo) is a putative neuroprotective therapy that did not improve overall outcomes in a phase 3 randomized controlled trial for neonates with moderate or severe hypoxic-ischemic encephalopathy (HIE). However, HIE is a heterogeneous disorder, and it remains to be determined whether Epo had beneficial effects on a subset of perinatal brain injuries. METHODS: This study was a secondary analysis of neuroimaging data from the High-dose Erythropoietin for Asphyxia and Encephalopathy (HEAL) Trial, which was conducted from 2016 - 2021 at 17 sites involving 23 US academic medical centers...
October 31, 2023: Developmental Neuroscience
https://read.qxmd.com/read/37904466/inadvertent-hypothermia-in-patients-undergoing-brachytherapy-under-monitored-anesthesia-care-a-prospective-observational-cohort-study
#27
JOURNAL ARTICLE
Ismail Aytac, Betül Guven Aytac, Aysun Postaci
Brachytherapy, which is often performed under anesthesia, is one of the main treatment options for cervical cancer. It is unclear whether hypothermia and its associated negative outcomes are encountered during this procedure. This prospective observational cohort study aimed to investigate the prevalence and adverse effects of hypothermia during serial brachytherapies under deep sedation for cervical cancer. Female patients over the aged > of 18 years who underwent were taken to serial brachytherapy sessions under deep sedation on alternate dates at most twice a week for the treatment of cervical cancer were included...
October 27, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/37812305/sleep-deprivation-soon-after-recovery-from-synthetic-torpor-enhances-tau-protein-dephosphorylation-in-the-rat-brain
#28
JOURNAL ARTICLE
Timna Hitrec, Fabio Squarcio, Emiliana Piscitiello, Matteo Cerri, Davide Martelli, Alessandra Occhinegro, Ludovico Taddei, Domenico Tupone, Roberto Amici, Marco Luppi
Neuronal Tau protein hyperphosphorylation (PPtau) is a hallmark of tauopathic neurodegeneration. However, a reversible brain PPtau occurs in mammals during either natural or "synthetic" torpor (ST), a transient deep hypothermic state that can be pharmacologically induced in rats. Since in both conditions a high sleep pressure builds up during the regaining of euthermia, the aim of this work was to assess the possible role of post-ST sleep in PPtau dephosphorylation. Male rats were studied at the hypothermic nadir of ST, and 3-6 h after the recovery of euthermia, after either normal sleep (NS) or total sleep deprivation (SD)...
October 9, 2023: Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
https://read.qxmd.com/read/37796292/a-century-of-exercise-physiology-concepts-that-ignited-the-study-of-human-thermoregulation-part-3-heat-and-cold-tolerance-during-exercise
#29
REVIEW
Sean R Notley, Duncan Mitchell, Nigel A S Taylor
In this third installment of our four-part historical series, we evaluate contributions that shaped our understanding of heat and cold stress during occupational and athletic pursuits. Our first topic concerns how we tolerate, and sometimes fail to tolerate, exercise-heat stress. By 1900, physical activity with clothing- and climate-induced evaporative impediments led to an extraordinarily high incidence of heat stroke within the military. Fortunately, deep-body temperatures > 40 °C were not always fatal...
January 2024: European Journal of Applied Physiology
https://read.qxmd.com/read/37774643/deep-learning-to-optimize-magnetic-resonance-imaging-prediction-of-motor-outcomes-after-hypoxic-ischemic-encephalopathy
#30
JOURNAL ARTICLE
Zachary A Vesoulis, Shamik B Trivedi, Hallie F Morris, Robert C McKinstry, Yi Li, Amit M Mathur, Yvonne W Wu
BACKGROUND: Magnetic resonance imaging (MRI) is the gold standard for outcome prediction after hypoxic-ischemic encephalopathy (HIE). Published scoring systems contain duplicative or conflicting elements. METHODS: Infants ≥36 weeks gestational age (GA) with moderate to severe HIE, therapeutic hypothermia treatment, and T1/T2/diffusion-weighted imaging were identified. Adverse motor outcome was defined as Bayley-III motor score <85 or Alberta Infant Motor Scale <10th centile at 12 to 24 months...
December 2023: Pediatric Neurology
https://read.qxmd.com/read/37771668/case-report-unveiling-the-unforeseen-a-catastrophic-encounter-of-giant-aortic-aneurysm-rupture-during-re-sternotomy-in-a-patient-with-bicuspid-aortic-valve-and-previous-surgical-aortic-valve-replacement
#31
Hao Niu, Lu Liu, Xiangfeng Gong, Haochen Wang, Yingqiang Guo, Eryong Zhang, Zhenghua Xiao
Due to structural abnormalities in the leaflets, patients with bicuspid aortic valve (BAV) may develop isolated aortic valve disease, such as aortic regurgitation, aortic stenosis, or a combination of both. In addition to valvular pathology, numerous studies have indicated that approximately 40% of BAV patients exhibit aortic pathologies characterized by aortic dilatation. According to guidelines for valvular diseases, patients with BAV who require surgical aortic valve replacement (SAVR) and have a diameter of the aortic sinuses or ascending aorta ≥4...
2023: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/37753830/retrograde-cerebral-perfusion-may-decrease-stroke-risk-during-elective-aortic-arch-surgery
#32
JOURNAL ARTICLE
William B Keeling, David Tian, Woodrow Farrington, Deniz Goksedef, Jehangir J Appoo, Andras Hoffman, G Chad Hughes, Scott LeMaire, Bradley G Leshnower
OBJECTIVE: Controversy remains regarding the optimal neuroprotection strategy for elective hemiarch replacement (HEMI). This study sought to compare outcomes in patients who underwent HEMI utilizing the 2 most common contemporary methods of cerebral protection. METHODS: The ARCH international aortic database was queried, and 782 patients undergoing elective HEMI with circulatory arrest from 2007 to 2012 were identified. There were 418 patients who underwent HEMI using moderate hypothermia (nasopharyngeal temperature 20...
September 27, 2023: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://read.qxmd.com/read/37725287/mir-126-and-mir-146a-as-melatonin-responsive-biomarkers-for-neonatal-brain-ischemia
#33
JOURNAL ARTICLE
Maria Cristina Albertini, Tania Vanzolini, Serafina Perrone, Michael D Weiss, Giuseppe Buonocore, Valentina Dell'Orto, Walter Balduini, Silvia Carloni
Despite advances in obstetric and neonatal care, challenges remain in early identification of neonates with encephalopathy due to hypoxia-ischemia who are undergoing therapeutic hypothermia. Therefore, there is a deep search for biomarkers that can identify brain injury. The aims of this study were to investigate the serum and brain expressions of two potential biomarkers, miR-126/miR-146a, in a preclinical model of hypoxia-ischemia (HI)-induced brain injury, and to explore their modulation during melatonin treatment...
September 19, 2023: Journal of Molecular Neuroscience: MN
https://read.qxmd.com/read/37716892/risk-factors-for-stroke-development-after-thoracic-aortic-surgery
#34
JOURNAL ARTICLE
Akram M Zaaqoq, Jason Chang, Sri Raksha Pothapragada, Lindsay Ayers, Xue Geng, Jacqueline L Russell, Sadia Ilyas, Christian Shults
OBJECTIVES: Stroke after thoracic aortic surgery is a complication that is associated with poor outcomes. The aim is to characterize the intraoperative risk factors for stroke development. DESIGN: A retrospective analysis. SETTING: Tertiary, high-volume cardiac surgery center. PARTICIPANTS: Patients who had surgical repair of thoracic aortic diseases from January 1, 2017, through December 31, 2021. INTERVENTIONS: None...
December 2023: Journal of Cardiothoracic and Vascular Anesthesia
https://read.qxmd.com/read/37639312/erratum-rat-model-of-normothermic-ex-situ-perfused-heterotopic-heart-transplantation
#35
JOURNAL ARTICLE
(no author information available yet)
An erratum was issued for: Rat Model of Normothermic Ex-Situ Perfused Heterotopic Heart Transplantation. The Protocol section was updated. Section 4 of the Protocol was updated from: 4. Implantation Preparation of recipient Begin the recipient preparation 30 min before the cessation of ex situ perfusion. Anesthetize the recipient animal using the same method as mentioned in step 2.2. Place the rat in a supine position on the heating pad and insert the temperature probe into the rectum to maintain the body temperature at 37 °C...
August 28, 2023: Journal of Visualized Experiments: JoVE
https://read.qxmd.com/read/37565137/corrigendum-synthetic-torpor-triggers-a-regulated-mechanism-in-the-rat-brain-favoring-the-reversibility-of-tau-protein-hyperphosphorylation
#36
Fabio Squarcio, Timna Hitrec, Emiliana Piscitiello, Matteo Cerri, Catia Giovannini, Davide Martelli, Alessandra Occhinegro, Ludovico Taddei, Domenico Tupone, Roberto Amici, Marco Luppi
[This corrects the article DOI: 10.3389/fphys.2023.1129278.].
2023: Frontiers in Physiology
https://read.qxmd.com/read/37405458/the-effect-of-temperature-on-vascular-smooth-muscle-cooling-induced-vasodilation-in-deep-arteries-and-veins
#37
JOURNAL ARTICLE
Seham Mustafa
Blood vessels in the cardiovascular system include arteries and veins, which are responsible for moving blood to and from tissues around the body. Our previous studies showed that cooling induces relaxation of arteries. The aim of this study is to investigate the effect of cooling on both arteries and veins pairs. Isometric tension was recorded in rat artery ring preparations (aorta, carotid, pulmonary arteries) and their vein pairs (vena cava, jugular, pulmonary veins) in organ baths during stepwise cooling from 37 to 4 °C...
July 5, 2023: Pflügers Archiv: European Journal of Physiology
https://read.qxmd.com/read/37374211/a-strategy-for-minimizing-circulatory-arrest-duration-in-complex-aortic-arch-procedures
#38
JOURNAL ARTICLE
Robert Balan, Petar Soso, Parwis Massoudy, Till Proschek, Wiebke Kurre, Christian Mogilansky
Background and Objectives : Aortic arch pathologies represent a surgical challenge. The challenge is partly due to the necessity of complex cerebral, visceral, and myocardial protection measures. Aortic arch surgery generally requires a significant duration of circulatory arrest, which includes deep hypothermia levels with the associated sequelae. This retrospective observational study shows the feasibility of a strategy that reduces circulatory arrest duration and eliminates the need for deep hypothermia during the procedure...
May 24, 2023: Medicina
https://read.qxmd.com/read/37278014/validation-of-a-new-model-of-selective-antegrade-cerebral-perfusion-with-circulatory-arrest-in-rats
#39
JOURNAL ARTICLE
Daniele Linardi, Romel Mani, Venanzio Di Nicola, Fabiola Perrone, Sara Martinazzi, Maddalena Tessari, Giuseppe Faggian, Giovanni Battista Luciani, Alessio Rungatscher
BACKGROUND: Selective antegrade cerebral perfusion (SACP) is adopted as an alternative to deep hypothermic circulatory arrest (DHCA) during aortic arch surgery. However, there is still no preclinical evidence to support the use of SACP associated with moderate hypothermia (28-30°C) instead of DHCA (18-20°C). The present study aims to develop a reliable and reproducible preclinical model of cardiopulmonary bypass (CPB) with SACP applicable for assessing the best temperature management...
June 5, 2023: Perfusion
https://read.qxmd.com/read/37240576/cerebral-perfusion-and-neuromonitoring-during-complex-aortic-arch-surgery-a-narrative-review
#40
REVIEW
Andrea Montisci, Giulia Maj, Corrado Cavozza, Andrea Audo, Stefano Benussi, Fabrizio Rosati, Sergio Cattaneo, Lorenzo Di Bacco, Federico Pappalardo
Complex ascending and aortic arch surgery requires the implementation of different cerebral protection strategies to avoid or limit the probability of intraoperative brain damage during circulatory arrest. The etiology of the damage is multifactorial, involving cerebral embolism, hypoperfusion, hypoxia and inflammatory response. These protective strategies include the use of deep or moderate hypothermia to reduce the cerebral oxygen consumption, allowing the toleration of a variable period of absence of cerebral blood flow, and the use of different cerebral perfusion techniques, both anterograde and retrograde, on top of hypothermia, to avoid any period of intraoperative brain ischemia...
May 15, 2023: Journal of Clinical Medicine
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