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https://www.readbyqxmd.com/read/29341851/underutilization-of-supplemental-magnetic-resonance-imaging-screening-among-patients-at-high-breast-cancer-risk
#1
Randy Miles, Fei Wan, Tracy L Onega, Amanda Lenderink-Carpenter, Ellen S O'Meara, Weiwei Zhu, Louise M Henderson, Jennifer S Haas, Deirdre A Hill, Anna N A Tosteson, Karen J Wernli, Jennifer Alford-Teaster, Janie M Lee, Constance D Lehman, Christoph I Lee
BACKGROUND: Women at high lifetime breast cancer risk may benefit from supplemental breast magnetic resonance imaging (MRI) screening, in addition to routine mammography screening for earlier cancer detection. MATERIALS AND METHODS: We performed a cross-sectional study of 422,406 women undergoing routine mammography screening across 86 Breast Cancer Surveillance Consortium (BCSC) facilities during calendar year 2012. We determined availability and use of on-site screening breast MRI services based on woman-level characteristics, including >20% lifetime absolute risk using the National Cancer Institute risk assessment tool...
January 17, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29324859/magnetic-resonance-spectroscopy-detects-differential-lipid-composition-in-mammary-glands-on-low-fat-high-animal-fat-versus-high-fructose-diets
#2
Dianning He, Devkumar Mustafi, Xiaobing Fan, Sully Fernandez, Erica Markiewicz, Marta Zamora, Jeffrey Mueller, Joseph R Sachleben, Matthew J Brady, Suzanne D Conzen, Gregory S Karczmar
The effects of consumption of different diets on the fatty acid composition in the mammary glands of SV40 T-antigen (Tag) transgenic mice, a well-established model of human triple-negative breast cancer, were investigated with magnetic resonance spectroscopy and spectroscopic imaging. Female C3(1) SV40 Tag transgenic mice (n = 12) were divided into three groups at 4 weeks of age: low fat diet (LFD), high animal fat diet (HAFD), and high fructose diet (HFruD). MRI scans of mammary glands were acquired with a 9...
2018: PloS One
https://www.readbyqxmd.com/read/29317373/impact-of-an-abbreviated-protocol-for-breast-mri-in-diagnostic-accuracy
#3
Guillaume Oldrini, Imad Derraz, Julia Salleron, Frédéric Marchal, Philippe Henrot
PURPOSE: We aimed to compare the diagnostic accuracy and interpretation time of an abbreviated protocol relative to the complete protocol of breast magnetic resonance imaging (MRI) with the use of breast imaging reporting and data system (BI-RADS). Between-reader and between-protocol variability for BI-RADS classification and influence of reader expertise on diagnostic accuracies were also evaluated. METHODS: We conducted a retrospective reader study in 90 women who underwent breast MRI: 30 benign examinations (graded as American College of Radiology [ACR] 1 or 2), 30 examinations graded as ACR 3 and 30 examinations requiring a histologic proof (graded as ACR 4 or 5)...
January 2018: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/29317039/clinical-breast-magnetic-resonance-imaging-technique-indications-and-future-applications
#4
Heather I Greenwood, Rita I Freimanis, Bianca M Carpentier, Bonnie N Joe
Breast magnetic resonance imaging (MRI) is the most sensitive imaging modality for the detection of breast cancer, and it is indicated for breast cancer screening in patients at high-risk of developing breast cancer. It is limited to this group given the high cost. In addition, breast MRI is also indicated for evaluating the extent of disease in patients with new breast cancer diagnoses, monitoring the response to neoadjuvant treatment, and evaluating implant integrity. New promising innovations in breast MRI include fast abbreviated MRI, and functional techniques including diffusion-weighted imaging and magnetic resonance spectroscopy are promising particularly as regards to treatment response...
February 2018: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29295753/differentiation-between-malignant-and-benign-breast-masses-combination-of-semi-quantitative-analysis-on-dce-mri-and-histogram-analysis-of-adc-maps
#5
H-L Liu, M Zong, H Wei, J-J Lou, S-Q Wang, Q-G Zou, H-B Shi, Y-N Jiang
AIM: To investigate the performance of combined semi-quantitative analysis on dynamic contrast enhanced (DCE) magnetic resonance imaging (MRI) and histogram analysis of diffusion-weighted imaging (DWI) for distinguishing malignant from benign breast masses. MATERIALS AND METHODS: This study included 178 patients with breast masses (benign:malignant=88:9) who underwent both DCE-MRI and DWI. The semi-quantitative parameters, derived from DCE-MRI, included maximum slope of increase (MSI), signal intensity slope (SIslope), initial percentage of enhancement (Einitial), percentage of peak enhancement (Epeak), early signal enhancement ratio (ESER), and second enhancement percentage (SEP)...
December 30, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29278946/experimental-assessment-of-phase-aberration-correction-for-breast-mrgfus-therapy
#6
Christopher R Dillon, Alexis Farrer, Hailey McLean, Scott Almquist, Douglas Christensen, Allison Payne
PURPOSE: This study validates that phase aberrations in breast magnetic resonance-guided focused ultrasound (MRgFUS) therapies can be corrected in a clinically relevant time frame to generate more intense, smaller and more spatially accurate foci. MATERIALS AND METHODS: Hybrid Angular Spectrum (HAS) ultrasound calculations in an MRI-based tissue model were used to compute phase aberration corrections for improved experimental MRgFUS heating in four heterogeneous breast-mimicking phantoms (N = 18 total locations)...
December 26, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/29246403/considerations-for-sentinel-lymph-node-biopsy-in-breast-cancer-patients-with-biopsy-proven-axillary-disease-prior-to-neoadjuvant-treatment
#7
Linda T Qu, Stephanie Peters, Adrienne N Cobb, Constantine V Godellas, Claudia B Perez, Faaiza T Vaince
BACKGROUND: Axillary disease can be downstaged with neoadjuvant treatment for breast cancer. We attempted to identify factors to consider in determining whether to perform a sentinel lymph node biopsy in patients with biopsy proven axillary metastases (cN+) prior to neoadjuvant treatment. METHODS: A retrospective chart review was conducted on patients at a single tertiary care center who underwent neoadjuvant treatment followed by surgery between 9/2013 and 2/2017...
November 13, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/29214373/utilization-of-breast-cancer-screening-with-magnetic-resonance-imaging-in-community-practice
#8
Deirdre A Hill, Jennifer S Haas, Robert Wellman, Rebecca A Hubbard, Christoph I Lee, Jennifer Alford-Teaster, Karen J Wernli, Louise M Henderson, Natasha K Stout, Anna N A Tosteson, Karla Kerlikowske, Tracy Onega
BACKGROUND: Breast cancer screening with magnetic resonance imaging (MRI) may be a useful adjunct to screening mammography in high-risk women, but MRI uptake may be increasing rapidly among low- and average-risk women for whom benefits are unestablished. Comparatively little is known about use of screening MRI in community practice. OBJECTIVE: To assess relative utilization of MRI among women who do and do not meet professional society guidelines for supplemental screening, and describe utilization according to breast cancer risk indications...
December 6, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29204279/sellar-plasmacytoma-presenting-with-symptoms-of-anterior-pituitary-dysfunction
#9
Ana G Ferreira, Tiago N Silva, Henrique V Luiz, Filipa D Campos, Maria C Cordeiro, Jorge R Portugal
Sellar plasmacytomas are rare and the differential diagnosis with non-functioning pituitary adenomas might be difficult because of clinical and radiological resemblance. They usually present with neurological signs and intact anterior pituitary function. Some may already have or eventually progress to multiple myeloma. We describe a case associated with extensive anterior pituitary involvement, which is a rare form of presentation. A 68-year-old man was referred to our Endocrinology outpatient clinic due to gynecomastia, reduced libido and sexual impotence...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/29178258/feasibility-analysis-of-early-temporal-kinetics-as-a-surrogate-marker-for-breast-tumor-type-grade-and-aggressiveness
#10
Laura Heacock, Alana A Lewin, Yiming Gao, James S Babb, Samantha L Heller, Amy N Melsaether, Neeti Bagadiya, Sungheon G Kim, Linda Moy
BACKGROUND: Screening breast MRI has been shown to preferentially detect high-grade ductal carcinoma in situ (DCIS) and invasive carcinoma, likely due to increased angiogenesis resulting in early initial uptake of contrast. As interest grows in abbreviated screening breast MRI (AB-MRI), markers of early contrast washin that can predict tumor grade and potential aggressiveness are of clinical interest. PURPOSE: To evaluate the feasibility of using the initial enhancement ratio (IER) as a surrogate marker for tumor grade, hormone receptor status, and prognostic markers, as an initial step to being incorporated into AB-MRI...
November 27, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29142626/resection-and-observation-for-brain-metastasis-without-prompt-postoperative-radiation-therapy
#11
Tae-Wook Song, In-Young Kim, Shin Jung, Tae-Young Jung, Kyung-Sub Moon, Woo-Youl Jang
Objective: Total resection without consecutive postoperative whole brain radiation therapy is indicated for patients with a single or two sites of brain metastasis, with close follow-up by serial magnetic resonance imaging (MRI). In this study, we explored the effectiveness, usefulness, and safety of this follow-up regimen. Methods: From January 2006 to December 2015, a total of 109 patients (76 males, 33 females) underwent tumor resection as the first treatment for brain metastases (97 patients with single metastases, 12 with two metastases)...
November 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29140576/comparison-between-qualitative-and-quantitative-assessment-of-background-parenchymal-enhancement-on-breast-mri
#12
Akshat C Pujara, Artem Mikheev, Henry Rusinek, Yiming Gao, Chloe Chhor, Kristine Pysarenko, Harikrishna Rallapalli, Jerzy Walczyk, Melanie Moccaldi, James S Babb, Amy N Melsaether
BACKGROUND: Potential clinical implications of the level of background parenchymal enhancement (BPE) on breast MRI are increasing. Currently, BPE is typically evaluated subjectively. Tests of concordance between subjective BPE assessment and computer-assisted quantified BPE have not been reported. PURPOSE OR HYPOTHESIS: To compare subjective radiologist assessment of BPE with objective quantified parenchymal enhancement (QPE). STUDY TYPE: Cross-sectional observational study...
November 15, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29139055/downstream-breast-imaging-following-screening-mammography-in-medicare-patients-with-advanced-cancer-a-population-based-study
#13
Gelareh Sadigh, Richard Duszak, Kevin C Ward, Renjian Jiang, Jeffrey M Switchenko, Kimberly E Applegate, Ruth C Carlos
BACKGROUND: Screening tests are generally not recommended in patients with advanced cancer and limited life expectancy. Nonetheless, screening mammography still occurs and may lead to follow-up testing. OBJECTIVE: We assessed the frequency of downstream breast imaging following screening mammography in patients with advanced colorectal or lung cancer. DESIGN: Population-based study. PARTICIPANTS: The study included continuously enrolled female fee-for-service Medicare beneficiaries ≥65 years of age with advanced colorectal (stage IV) or lung (stage IIIB-IV) cancer reported to a Surveillance, Epidemiology, and End Results (SEER) registry between 2000 and 2011...
November 14, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29127715/relationship-between-preoperative-breast-mri-and-surgical-treatment-of-non-metastatic-breast-cancer
#14
Tracy Onega, Julie E Weiss, Martha E Goodrich, Weiwei Zhu, Wendy B DeMartini, Karla Kerlikowske, Elissa Ozanne, Anna N A Tosteson, Louise M Henderson, Diana S M Buist, Karen J Wernli, Sally D Herschorn, Elise Hotaling, Cristina O'Donoghue, Rebecca Hubbard
BACKGROUND AND OBJECTIVES: More extensive surgical treatments for early stage breast cancer are increasing. The patterns of preoperative MRI overall and by stage for this trend has not been well established. METHODS: Using Breast Cancer Surveillance Consortium registry data from 2010 through 2014, we identified women with an incident non-metastatic breast cancer and determined use of preoperative MRI and initial surgical treatment (mastectomy, with or without contralateral prophylactic mastectomy (CPM), reconstruction, and breast conserving surgery ± radiation)...
December 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29125427/the-surgical-treatment-of-metastatic-spine-tumors-within-the-intramedullary-compartment
#15
Ben A Strickland, Ian E McCutcheon, Indro Chakrabarti, Laurence D Rhines, Jeffrey S Weinberg
OBJECTIVE Metastasis to the spinal cord is rare, and optimal management of this disease is unclear. The authors investigated this issue by analyzing the results of surgical treatment of spinal intramedullary metastasis (IM) at a major cancer center. METHODS The authors retrospectively reviewed the medical records of 13 patients who underwent surgery for IM. Patients had renal cell carcinoma (n = 4), breast carcinoma (n = 3), melanoma (n = 2), non-small cell lung cancer (n = 1), sarcoma (n = 1), adenoid cystic carcinoma (n = 1), and cervical cancer (n = 1)...
November 10, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29120813/visibility-of-mammographically-occult-breast-cancer-on-diffusion-weighted-mri-versus-ultrasound
#16
Nita Amornsiripanitch, Habib Rahbar, Averi E Kitsch, Diana L Lam, Brett Weitzel, Savannah C Partridge
PURPOSE: To investigate the visibility of mammographically occult breast cancers on diffusion-weighted MRI (DWI) versus ultrasound. MATERIALS AND METHODS: Mammographically occult breast cancers (n=60) initially detected on contrast-enhanced MRI that underwent pre-biopsy targeted ultrasound were retrospectively evaluated for visibility on DWI and ultrasound. RESULTS: More cancers were visible on DWI than ultrasound (78% vs. 63%; p=0.049), with 32 (53%) visible on both and 7 (12%) not visible on either...
October 28, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29103479/is-breast-magnetic-resonance-imaging-mri-useful-for-diagnosis-of-additional-sites-of-disease-in-patients-recently-diagnosed-with-pure-ductal-carcinoma-in-situ-dcis
#17
A P Benveniste, T Ortiz-Perez, L O Ebuoma, K A Sepulveda, F J Severs, A Roark, T Wang, E L Sedgwick
PURPOSE: To determine if breast MRI is useful for detecting additional or invasive sites of disease in patients initially diagnosed with pure DCIS. MATERIALS AND METHODS: A retrospective review of women diagnosed with pure DCIS who underwent a breast MRI for evaluation of extent of disease was performed at a single institution from January 2013 to April 2015. Data analysis included imaging (mammography, ultrasound and MRI) and pathology characteristics (histology and biomarker status) of the primary DCIS as well as descriptors for the additional sites of disease incidentally found by breast MRI...
November 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29072415/impact-of-a-stress-management-intervention-program-on-sexual-functioning-and-stress-reduction-in-women-with-breast-cancer
#18
Arezoo Shayan, Farkhondeh Jamshidi, Vahid Tahmasebiboldaji, Somayeh Khani, Maryam Babaei, Mohamad Reza Havasian, Seyedeh Zahra Masoumi
Breast cancer as the most common cancer among women endangers various aspects of their sexual lives and is a major culprit regarding health impairment and low life quality. The aim of this study was to examine the effect of a stress management intervention program on sexual functioning and stress reduction in women with breast cancer. This study employed a quasi-experimental pre-test, post-test design which included follow-up checks and a control group. To this end, 104 women with breast cancer referring to Hamadan’s Mahdiyeh MRI Center at the time of data collection were conventionally selected in 2015...
October 26, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29061022/-preoperative-dynamic-contrast-enhanced-mri-can-reduce-the-rate-of-tumor-positive-resection-margins-after-breast-conserving-surgery-in-patients-with-early-non-mass-breast-carcinoma
#19
X S Li, Y L Song, D C Li, H X Zhu, L M Meng, R R Huang, S L Wang, D Wang, H Fang, H X Fan
Objective: To investigate the value of preoperative dynamic contrast-enhanced MRI in reducing the rate of tumor-positive resection margins after breast conserving surgery in patients with early non-mass breast carcinoma. Methods: Seventy-two patients with early non-mass breast carcinoma received ultrasonographic and mammographic examination and subsequently underwent dynamic contrast-enhanced MRI examination before breast conserving surgery. The control group consisted of 74 patients who had early non-mass breast carcinoma...
October 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/29044896/support-vector-machine-for-breast-cancer-classification-using-diffusion-weighted-mri-histogram-features-preliminary-study
#20
Igor Vidić, Liv Egnell, Neil P Jerome, Jose R Teruel, Torill E Sjøbakk, Agnes Østlie, Hans E Fjøsne, Tone F Bathen, Pål Erik Goa
BACKGROUND: Diffusion-weighted MRI (DWI) is currently one of the fastest developing MRI-based techniques in oncology. Histogram properties from model fitting of DWI are useful features for differentiation of lesions, and classification can potentially be improved by machine learning. PURPOSE: To evaluate classification of malignant and benign tumors and breast cancer subtypes using support vector machine (SVM). STUDY TYPE: Prospective. SUBJECTS: Fifty-one patients with benign (n = 23) and malignant (n = 28) breast tumors (26 ER+, whereof six were HER2+)...
October 16, 2017: Journal of Magnetic Resonance Imaging: JMRI
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