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https://www.readbyqxmd.com/read/29037006/microrna-150-5p-improves-risk-classification-for-mortality-within-90-days-after-acute-ischemic-stroke
#1
Natalie Scherrer, Francois Fays, Beat Mueller, Andreas Luft, Felix Fluri, Mirjam Christ-Crain, Yvan Devaux, Mira Katan
BACKGROUND AND PURPOSE: Micro ribonucleic acid-150-5p (miR-150-5p) regulates proinflammatory cytokines as well as vessel integrity. We evaluated the incremental prognostic value of logarithm (log) of miR-150-5p plasma levels after ischemic stroke. METHODS: In a prospective cohort study, levels of miR-150-5p were measured within 72 hours of symptom onset in 329 ischemic stroke patients. The outcome measures were unfavorable functional outcome (assessed by the modified Rankin Scale score >2) and mortality within 90 days...
September 2017: Journal of Stroke
https://www.readbyqxmd.com/read/29036973/-predictive-value-of-cardiac-magnetic-resonance-derived-parameters-on-the-improvement-of-left-ventricular-function-in-patients-with-acute-viral-myocarditis
#2
H C Ouyang, F C Ouyang, L L Mai, Y Y Chen, Y Z Hu, H X Chen, W S Li
Objective: To evaluate the predictive value of cardiac magnetic resonance (CMR)-derived parameters on the improvement of left ventricular function in patients with acute viral myocarditis. Methods: Forty patients, who referred for acute viral myocarditis in our hospital from September 2011 to September 2015, were prospectively enrolled in this study.All patients were examined by CMR during hospitalization for acute viral myocarditis (baseline) and after 12 months.The CMR sequences include: two dimension steady state free precession, 2D SSFP; triple inversion recovery, triple IR; early gadolinium enhancement; phase sensitive inversion recovery turbo field echo, PSIR TFE...
September 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29036954/-relationship-between-highly-sensitive-cardiac-troponin-t-and-sepsis-and-outcome-in-critically-ill-patients
#3
T T Wang, L Jiang
Objective: To investigate the prognostic value of highly sensitive cardiac Troponin T (hs-cTn T) for sepsis in critically ill patients. Methods: Patients estimated to stay in the ICU of Fuxing Hospital for more than 24h were enrolled at from March 2014 to December 2014. Serum hs-cTn T was tested within two hours. Univariate and multivariate linear regression analyses were used to determine the association of variables with the hs-cTn T. Multivariable logistic regression analysis was used to evaluate the risk factors of 28-day mortality...
October 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29036941/breast-implant-associated-anaplastic-large-cell-lymphoma-in-a-transgender-woman
#4
Mintsje de Boer, Wouter B van der Sluis, Jan P de Boer, Lucy I H Overbeek, Flora E van Leeuwen, Hinne A Rakhorst, René R W J van der Hulst, Nathalie J Hijmering, Mark-Bram Bouman, Daphne de Jong
Breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL) is a rare but serious complication in patients with breast implants, Patients are at risk of BIA-ALCL whether they receive breast implants for cosmetic reasons or for reconstructive purposes after surgery for breast cancer or prophylactic mastectomy. During the past decade, an increased number of reports have addressed BIA-ALCL. Herein, we describe BIA-ALCL in a transgender woman. The patient received breast implants as part of her gender transition and was diagnosed with BIA-ALCL 20 years later...
September 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29036895/low-cost-lab-on-chip-for-the-colorimetric-detection-of-nitrate-in-mineral-water-products
#5
Mohammad F Khanfar, Wisam Al-Faqheri, Ala'aldeen Al-Halhouli
The diagnostics of health status and the quality of drinking water are among the most important United Nations sustainable development goals. However, in certain areas, wars and instability have left millions of people setting in refugee camps and dangerous regions where infrastructures are lacking and rapid diagnostics of water quality and medical status are critical. In this work, microfluidic testing chips and photometric setups are developed in cheap and portable way to detect nitrate concentrations in water...
October 14, 2017: Sensors
https://www.readbyqxmd.com/read/29036889/single-administration-of-melatonin-modulates-the-nitroxidergic-system-at-the-peripheral-level-and-reduces-thermal-nociceptive-hypersensitivity-in-neuropathic-rats
#6
Elisa Borsani, Barbara Buffoli, Veronica Bonazza, Russel J Reiter, Rita Rezzani, Luigi F Rodella
Neuropathic pain is a severe condition with unsatisfactory treatments. Melatonin, an indolamine, seems to be a promising molecule suitable for this purpose due to its well-known anti-inflammatory, analgesic, and antioxidant effects, as well as its modulation of the nitroxidergic system. Nevertheless, the data on its mechanism of action and potentialities are currently insufficient in this pathology, especially at the peripheral level. Thus, this work evaluated the effect of a single administration of melatonin in an established mononeuropathy pain model that monitors the behaviour and the changes in the nitroxidergic system in dorsal root ganglia and skin, which are affected by nervous impairment...
October 14, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29036886/model-based-real-time-non-rigid-tracking
#7
Sebastián Bronte, Luis M Bergasa, Daniel Pizarro, Rafael Barea
This paper presents a sequential non-rigid reconstruction method that recovers the 3D shape and the camera pose of a deforming object from a video sequence and a previous shape model of the object. We take PTAM (Parallel Mapping and Tracking), a state-of-the-art sequential real-time SfM (Structure-from-Motion) engine, and we upgrade it to solve non-rigid reconstruction. Our method provides a good trade-off between processing time and reconstruction error without the need for specific processing hardware, such as GPUs...
October 14, 2017: Sensors
https://www.readbyqxmd.com/read/29036883/microrna-34a-a-versatile-regulator-of-myriads-of-targets-in-different-cancers
#8
REVIEW
Ammad Ahmad Farooqi, Sobia Tabassum, Aamir Ahmad
MicroRNA-34a (miR-34a) is a tumor suppressor that has attracted considerable attention in recent years. It modulates cancer cell invasion, metastasis, and drug resistance, and has also been evaluated as a diagnostic and/or prognostic biomarker. A number of targets of miR-34a have been identified, including some other non-coding RNAs, and it is believed that the modulation of these myriads of targets underlines the versatile role of miR-34a in cancer progression and pathogenesis. Seemingly appealing results from preclinical studies have advocated the testing of miR-34a in clinical trials...
October 2, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29036879/enhancement-of-digital-radiography-image-quality-using-a-convolutional-neural-network
#9
Yuewen Sun, Litao Li, Peng Cong, Zhentao Wang, Xiaojing Guo
Digital radiography system is widely used for noninvasive security check and medical imaging examination. However, the system has a limitation of lower image quality in spatial resolution and signal to noise ratio. In this study, we explored whether the image quality acquired by the digital radiography system can be improved with a modified convolutional neural network to generate high-resolution images with reduced noise from the original low-quality images. The experiment evaluated on a test dataset, which contains 5 X-ray images, showed that the proposed method outperformed the traditional methods (i...
October 10, 2017: Journal of X-ray Science and Technology
https://www.readbyqxmd.com/read/29036876/image-artifacts-and-noise-reduction-algorithm-for-cone-beam-computed-tomography-with-low-signal-projections
#10
Fu-Qiang Yang, Ding-Hua Zhang, Kui-Dong Huang, Ya-Fei Yang, Jin-Ming Liao
This study aims to investigate and test a new image reconstruction algorithm applying to the low-signal projections to generate high quality images by reducing the artifacts and noise in the cone-beam computed tomography (CBCT). For the low-signal and noisy projections, a multiple sampling method is first utilized in projection domain to suppress environmental noise, which guarantees the accuracy of the data for reconstruction, simultaneously. Next, a fuzzy entropy based method with block matching 3D (BM3D) filtering algorithm is employed to improve the image quality to reduce artifacts and noise in image domain...
October 10, 2017: Journal of X-ray Science and Technology
https://www.readbyqxmd.com/read/29036874/development-of-a-device-to-reduce-the-risk-of-injury-in-handling-unstable-loads
#11
Mohamed Zaki Ramadan, Mohammed Alkahtani
BACKGROUND: Manual material handling (MMH) task is the most common cause of work-related musculoskeletal disorders (MSDs). Operators carrying unstable loads were recently shown to be at greater risk of back injury compared to workers carrying stable loads. OBJECTIVE: This study focused on developing a device to minimize trunk muscle activity and cardiovascular demand while handling a 19-liter bottle. METHOD: After evaluating several designs, one was selected to be developed, manufactured and tested through an experimental study...
October 10, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/29036862/naval-special-warfare-nsw-crewmen-demonstrate-diminished-cervical-strength-and-range-of-motion-compared-to-nsw-students
#12
Shawn R Eagle, Takashi Nagai, Paul Morgan, Renee Hendershot, Timothy C Sell
BACKGROUND: Cumulative effects of high-impact vertical forces, like those experienced on an open-ocean mission, could be an injury concern for the cervical spine. OBJECTIVE: Compare cervical range of motion (ROM) and strength measures between students and NSW Crewmen and secondarily to compare these measures between students and Crewmen separated into three groups based on years of service. METHODS: A volunteer sample of 186 students (age: 22...
October 9, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/29036861/task-intensity-influences-upper-limb-and-torso-kinematics-during-two-common-overhead-functional-capacity-evaluation-tasks
#13
Angelica E Lang, Clark R Dickerson
BACKGROUND: The Functional Capacity Evaluation (FCE) is a tool used in the return-to-work process to guide treatment and decision making. Individual abilities and maximum capacity can be determined through visual observations of changes in mechanics as intensity increases. OBJECTIVE: The purpose of this study was to determine kinematic differences between sexes and intensity levels of two common FCE tasks to establish normative behaviours. METHODS: Upper limb and torso kinematics were collected from 30 participants as they performed the overhead lift and overhead work FCE tasks...
October 8, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/29036851/a-novel-low-cost-approach-for-navigated-transcranial-magnetic-stimulation
#14
Jakob Rodseth, Edward P Washabaugh, Chandramouli Krishnan
BACKGROUND: Transcranial magnetic stimulation (TMS) is commonly used for assessing or modulating brain excitability. However, the credibility of TMS outcomes depends on accurate and reliable coil placement during stimulation. Navigated TMS systems can address this issue, but these systems are expensive for routine use in clinical and research environments. OBJECTIVE: The purpose of this study was to provide a high-quality open source framework for navigated TMS and test its reliability and accuracy using standard TMS procedures...
October 9, 2017: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/29036778/electronic-clinical-decision-support-tool-for-the-evaluation-of-cardiovascular-risk-in-general-practice-a-pilot-study
#15
Jason Chiang, John Furler, Douglas Boyle, Malcolm Clark, Jo-Anne Manski-Nankervis
BACKGROUND: Cardiovascular disease (CVD) is a major cause of death in Australia. Electronic medical record (EMR)-based clinical decision support (CDS) tools have the potential to support absolute CVD risk (ACVDR) evaluation and management. The objective of this study was to test the acceptability and feasibility of the Treat to Target CVD (T3CVD), an EMR-based CDS tool, for the evaluation of ACVDR in general practice. METHODS: Five general practitioners (GPs) piloted the T3CVD tool in their clinic...
October 2017: Australian Family Physician
https://www.readbyqxmd.com/read/29036707/introduction-and-testing-of-a-simplified-method-for-the-evaluation-of-the-radon-emanation
#16
F Kabrt, A Baumgartner, M Stietka, F J Maringer
The radioactive noble gas radon is identified as the highest risk factor for lung cancer after smoking. The exhalation of radon from building materials can contribute to the radon indoor activity concentration. Therefore, the emanation of radon might be a crucial factor. It is defined as the release of radon from the solid soil matter into the pore space of the material. This article describes a new on-site measurement method for the emanation of radon from building materials at industrial sites. Therefore, a closed vessel with sample material and a passive radon detector inside is used to measure the integrated build-up-curve of the activity concentration...
September 19, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/29036692/clinical-utility-of-texture-analysis-of-18f-fdg-pet-ct-in-patients-with-stage-i-lung-cancer-treated-with-stereotactic-body-radiotherapy
#17
Kazuya Takeda, Kentaro Takanami, Yuko Shirata, Takaya Yamamoto, Noriyoshi Takahashi, Kengo Ito, Kei Takase, Keiichi Jingu
We evaluated the reproducibility and predictive value of texture parameters and existing parameters of 18F-FDG PET/CT images in Stage I non-small-cell lung cancer (NSCLC) patients treated with stereotactic body radiotherapy (SBRT). Twenty-six patients with Stage I NSCLC (T1-2N0M0) were retrospectively analyzed. All of the patients underwent an 18F-FDG PET/CT scan before treatment and were treated with SBRT. Each tumor was delineated using PET Edge (MIM Software Inc., Cleveland, OH), and texture parameters were calculated using open-source code CGITA...
September 21, 2017: Journal of Radiation Research
https://www.readbyqxmd.com/read/29036627/using-uncertainty-to-link-and-rank-evidence-from-biomedical-literature-for-model-curation
#18
Chrysoula Zerva, Riza Batista-Navarro, Philip Day, Sophia Ananiadou
Motivation: In recent years, there has been great progress in the field of automated curation of biomedical networks and models, aided by text mining methods that provide evidence from literature. Such methods must not only extract snippets of text that relate to model interactions, but also be able to contextualize the evidence and provide additional confidence scores for the interaction in question. Although various approaches calculating confidence scores have focused primarily on the quality of the extracted information, there has been little work on exploring the textual uncertainty conveyed by the author...
July 24, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29036626/detection-of-an-underlying-22q11-2-duplication-in-a-female-neonate-with-trisomy-18
#19
Donald E Turbiville, Hai Wu, Jianli Dong
Current guidelines indicate that in patients with developmental disabilities or congenital anomalies, chromosomal microarray (CMA) is a first-tier diagnostic test. However, for patients with obvious chromosomal syndromes such as trisomy 13, 18, and 21, G-banded karyotyping is still recommended over CMA for establishing a diagnosis. In the case presented herein, a female neonate was suspected of having trisomy 18 based on pre- and postnatal evaluations. Karyotyping was requested but not performed due to insufficient cell growth; Interphase fluorescence in situ hybridization (i-FISH) found an extra copy of chromosome 18...
September 23, 2017: Laboratory Medicine
https://www.readbyqxmd.com/read/29036552/using-foliar-spectral-properties-to-assess-the-effects-of-drought-on-plant-water-potential
#20
Lorenzo Cotrozzi, John J Couture, Jeannine Cavender-Bares, Clayton C Kingdon, Beth Fallon, George Pilz, Elisa Pellegrini, Cristina Nali, Philip A Townsend
Drought frequency is predicted to increase in future environments. Leaf water potential (ΨLW) is commonly used to evaluate plant water status, but traditional measurements can be logistically difficult and require destructive sampling. We used reflectance spectroscopy to characterize variation in ΨLW of Quercus oleoides Schltdl. & Cham. under differential water availability and tested the ability to predict pre-dawn ΨLW (PDΨLW) using spectral data collected hours after pressure chamber measurements on dark-acclimated leaves...
September 19, 2017: Tree Physiology
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