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David Loja-Oropeza, Ernesto Zavala-Flores, Maricela Vilca-Vasquez
A 55-year-old female patient, born in Ayacucho, with a history of dermatomyositis for 3 years, who received irregular treatment with prednisone. Two months prior to admission, she presented with autoinmune hemolytic anemia and idiopathic thrombocytopenic purpura. The patient received methylprednisolone pulse therapy and packed red blood cells transfusions. Upon admission, she was drowsy, with a poor overall status, marked weight loss, dehydration, with presence of livedo reticularis in her lower extremities, and onychodystrophy and onycholysis on the toes of both feet...
March 2016: Revista Peruana de Medicina Experimental y Salud Pública
E Valdivielso Cortázar, C Prieto Martínez, I Fernández-Urién, J J Vila Costas, F J Jiménez Pérez, A Guerra Lacunza
Autoimmune pancreatitis (AIP) is an infrequent pathology, although there is a growing incidence in Eastern countries, which might be due to a greater rate of detection. It can be associated with other auto immune pathologies and its association with IgG4-related systemic disease has been described.Its clinical presentation is varied and the normal treatment is medical, using corticoids.A diagnosed clinical case is described.
2016: Anales del Sistema Sanitario de Navarra
Mónica Fernández Castro, Jose Luis Andreu, Carlos Sánchez-Piedra, Víctor Martínez Taboada, Alejandro Olivé, José Rosas, Fernando Sánchez-Alonso
OBJECTIVE: To describe the objectives and methods of the Spanish Society of Rheumatology primary Sjögren syndrome (pSS) registry (SJOGREN-SER) METHODS: This is a multicenter descriptive transversal study of a cohort of pSS patients fulfilling European/American consensus criteria collected from Rheumatology clinics all over Spain. Patients were included by randomisation from an anonymised list provided by every department. Data were collected by reviewing clinical records and an interviewing the patients...
July 2016: Reumatología Clinica
V T Ivashkinl, A F Sheptulina, K L Raĭkhelson, E A Losik, K V Ivashkin, A V Okhlobystin, E K Baranskaia, E A Polouvektova, O S Shifrin
Autoimmune diseases of digestive system refer to pathological conditions, caused by autoimmune mechanisms, and their etiology remains unknown. This is a group of relatively rare diseases, however, during the last years a marked tendency towards the raise in incidence andprevalence is observed, which led to an increase in number of clinical investigations on etiology, pathogenesis, and, accordingly, development of new diagnostic methods and therapies. Results of such trials shown, for example, that the pathogenesis of chronic cholestatic liver diseases is associated with nuclear receptors function, while the main etiological and pathogenic factor of inflammatory bowel diseases represents gut microbiota...
2015: Vestnik Rossiĭskoĭ Akademii Meditsinskikh Nauk
Aurora Alejandra Chávez-García, Miguel Ángel Moreno-Alba, Martín Elizalde-Monroy, Nora Hilda Segura-Méndez, Jovita Romero-Flores, Julio César Cambray-Gutiérrez, Patricia López-Pérez, Leonel Gerardo Del Rivero-Hernández
BACKGROUND: Common variable immunodeficiency is the primary immunodeficiency (CVID) frequently found in adults. Its prevalence is estimated from 1:25,000 to 75,000 alive newborns; there are variations by ethnic groups, it is estimated about 50-70% in Caucasian patients. Oral cavity lesions are rarely found in adult patients with CVID, there are reports about lesions on pediatric patients mostly caused by infections. OBJECTIVE: To describe the orofacial lesions (oral, maxillofacial and neck area) affecting adults with CVID...
April 2015: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
Miguel Ángel Saavedra Salinas, Antonio Barrera Cruz, Antonio Rafael Cabral Castañeda, Luis Javier Jara Quezada, C Alejandro Arce-Salinas, José Álvarez Nemegyei, Antonio Fraga Mouret, Javier Orozco Alcalá, Mario Salazar Páramo, Claudia Verónica Cruz Reyes, Lilia Andrade Ortega, Olga Lidia Vera Lastra, Claudia Mendoza Pinto, Antonio Sánchez González, Polita Del Rocío Cruz Cruz, Sara Morales Hernández, Margarita Portela Hernández, Mario Pérez Cristóbal, Gabriela Medina García, Noé Hernández Romero, María Del Carmen Velarde Ochoa, José Eduardo Navarro Zarza, Verónica Portillo Díaz, Angélica Vargas Guerrero, María Victoria Goycochea Robles, José Luis García Figueroa, Eduardo Barreira Mercado, Mary Carmen Amigo Castañeda
BACKGROUND: Pregnancy in women with autoimmune rheumatic diseases is associated with several maternal and fetal complications. The development of clinical practice guidelines with the best available scientific evidence may help standardize the care of these patients. OBJECTIVES: To provide recommendations regarding prenatal care, treatment, and a more effective monitoring of pregnancy in women with lupus erythematosus (SLE), rheumatoid arthritis (RA) and antiphospholipid antibody syndrome (APS)...
September 2015: Reumatología Clinica
Francisco Reyes-Baraona, Romina Andino, Juan Eduardo Carrasco, Camila Arriagada, Silvia Guerrero
Linear IgA bullous dermatosis is a rare acquired autoinmune vesiculobullous disease characterized by linear IgA deposit on the dermo-epidermal basement membrane observed with direct inmunofluorescence. The characteristic lesions are vesicles and tense serous bullae, which most often are grouped giving a "cluster of jewels" appearance. Differential diagnosis must be established with other autoimmune dermatosis, such as dermatitis herpetiformis and bullous pemphigoid. Dapsone is the first line therapy, with excellent response in a short period...
April 2014: Archivos Argentinos de Pediatría
Iñigo Rúa-Figueroa, Francisco Javier López-Longo, Jaime Calvo-Alén, María Galindo-Izquierdo, Estíbaliz Loza, M Jesús García de Yebenes, José M Pego-Reigosa
OBJECTIVE: To describe the objectives, design and methods of the Spanish Society of Rheumatology systemic lupus erythematosus (SLE) registry (RELESSER). METHODS: Multicenter, hospital-based registry, with retrospective collection of data from a large representative sample of adult patients with SLE (1997 ACR criteria) attending Spanish rheumatology services. The registry includes demographic data, frequent and infrequent (<1%) clinical manifestations, information about activity, damage, severity, comorbidity, treatments and mortality, collecting 359 variables per patient, with highly standardized definitions...
January 2014: Reumatología Clinica
M Ramos-Casals, G Ruiz-Irastorza, J Jiménez-Alonso, M A Khamashta
No abstract text is available yet for this article.
January 2013: Revista Clínica Espanõla
Marcela Saeb-Lima, Yann Charli-Joseph, Elva Dalia Rodríguez-Acosta, Judith Domínguez-Cherit
Neutrophilic dermatoses have long been known to be associated with autoinmune systemic diseases. Recently, a small number of cases of a disorder distinct from Sweet syndrome or bullous lupus erythematosus (LE) have been described as specifically related to systemic LE under diverse terms, including nonbullous neutrophilic dermatosis, nonbullous neutrophilic LE, and Sweet-like neutrophilic dermatosis. We describe 7 patients that developed urticarial lesions in the context of a known or concurrently diagnosed autoimmune connective tissue disease...
August 2013: American Journal of Dermatopathology
M Ramos-Casals, G Ruiz-Irastorza, J Jiménez-Alonso, M A Khamashta
Biological therapies are based on the administration of various types of synthetic molecules related to the immune response. Their use has spread in recent years to the field of systemic autoimmune diseases, particularly to systemic lupus erythematosus (SLE). Until 2011, these diseases were not included in the therapeutic indications approved by international regulatory agencies. Therefore, the use of biological therapies was restricted to clinical trials and to compassionate use for cases refractory to standard treatments (off-label use), which require the approval of the Health Ministry...
January 2013: Revista Clínica Espanõla
G Ruiz-Irastorza, G Espinosa, J Jiménez-Alonso, L Pallarés, A Robles
No abstract text is available yet for this article.
March 2012: Revista Clínica Española
G Ruiz-Irastorza, G Espinosa, M A Frutos, J Jiménez Alonso, M Praga, L Pallarés, F Rivera, Á Robles Marhuenda, A Segarra, C Quereda
No abstract text is available yet for this article.
March 2012: Revista Clínica Española
Gonzalo de Las Heras Castaño, Marcos López Hoyos
No abstract text is available yet for this article.
December 2011: Revista Española de Enfermedades Digestivas
Cándido Díaz-Lagares, Rafael Belenguer, Manuel Ramos-Casals
OBJECTIVE: To analyze published evidence about adalimumab use in autoimmune diseases. METHODS: Systematic review of MEDLINE database of citations included from January 1990 to December 2008 employing the terms "adalimumab" and the different systemic autoimmune diseases. RESULTS: Our search identified 241 potentially relevant citations. 154 were retrieved for detailed evaluation. Finally, 18 were selected as relevant, including 54 patients...
May 2010: Reumatología Clinica
Manuel Ramos-Casals, Cándido Díaz-Lagares, Munther A Khamashta et al.
No abstract text is available yet for this article.
March 12, 2011: Medicina Clínica
Rodrigo Rocamora, Antonio Gil-Nagel, Oriol Franch, Antonio Vela-Bueno
Kleine-Levin syndrome and menstrual-related hypersomnia are rare idiopathic sleep disorders occurring primarily in adolescence. They are characterized by intermittent periods of excessive sleepiness, cognitive disturbances, and behavioral abnormalities. In both, the etiology remains unknown but autoinmune, hormonal, infectious, and inflammatory mechanisms have been proposed. The authors describe, for the first time, the association of Kleine-Levin syndrome and menstrual-related hypersomnia in 2 adolescent siblings who shared the human leukocyte antigen (HLA) loci DQB1*0501...
November 2010: Journal of Child Neurology
L Pallarés Ferreres, M Ramos-Casals
No abstract text is available yet for this article.
March 2009: Farmacia Hospitalaria
Luis Ricardo Rodrigo Sáez
Celiac disease is a unique autoimmune disorder, because the environmental precipitant factor is known. It is gluten, the major storage protein of wheat and similar grains. Originally was considered a rare malabsorption syndrome of childhood, but nowadays is recognized a common condition, that affects to 1% of the general population, all over the world', involves to all different races, may be diagnosed at any age, and affects to many organ systems. Therapy for the disease is a gluten-free-diet that must be strict and long-term...
2008: Anales de la Real Academia Nacional de Medicina
Pedro Emilio Bermejo, Aurora Burgos
Although ulcerative colitis and Crohn's disease have traditionally been considered to be inflammatory diseases limited to the gastrointestinal tract, it has been shown that both pathologies are frequently accompanied by various extraintestinal disorders. There is an increasing evidence that they may also manifest in the nervous system, including the peripheral and the central parts. Although some of these neurological complications have been known for a long time, such as cerebrovascular disease, vasculitis and autoinmune processes including neuropathies and cerebral demyelination, others have been recently described...
May 10, 2008: Medicina Clínica
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