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https://www.readbyqxmd.com/read/28633314/qualitative-identification-of-fentanyl-analogs-and-other-opioids-in-postmortem-cases-by-uhplc-ion-trap-msn
#1
Elisa N Shoff, M Elizabeth Zaney, Joseph H Kahl, George W Hime, Diane M Boland
Since 2013, the Miami-Dade County Medical Examiner Department has experienced an increase in the number of opioid-related deaths. The majority of cases coincided with the introduction of fentanyl into the local heroin supply. From 2014 to 2015, Miami-Dade County experienced a near 600% increase in fentanyl-related deaths, followed by an additional 200% increase in 2016. In 2015, two novel fentanyl analogs were identified in medical examiner cases: beta-hydroxythiofentanyl and acetyl fentanyl. In 2016, four additional fentanyl analogs emerged: para-fluoroisobutyryl fentanyl, butyryl fentanyl, furanyl fentanyl and carfentanil, as well as the synthetic opioid U-47700...
June 13, 2017: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/28631433/forensic-radiology-pitfalls-ct-imaging-in-gunshot-wounds-of-the-head
#2
Mark A Giffen, Jason A Powell, Jerri McLemore
Computed tomography (CT) imaging is increasingly used in emergency departments and trauma services and is being offered as a supplemental tool with autopsy in coroner's and medical examiner's offices throughout the United States. The availability of CT images in lieu of traditional X-rays for medicolegal autopsies may lead to misinterpretation of images for forensic pathologists who are not familiar with these types of images. Forensic pathologists must become familiar with CT imaging, the basis of CT image formation and how to interpret CT images appropriately...
June 20, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28630844/multifocal-septic-arthritis-secondary-to-infective-endocarditis-a-rare-case-report
#3
Pavandeep Soor, Nikhil Sharma, Chandra Rao
INTRODUCTION: Infective endocarditis (IE) is a rare cause of septic arthritis. We report a patient who presented with multifocal septic arthritis as a result of IE, which is an extremely rare condition. CASE REPORT: This 69-year-old gentleman presented to the emergency department (ED) with a 3-day history of acute right knee pain. Initial investigations demonstrated chondrocalcinosis on knee radiographs, acute renal failure with rhabdomyolysis and a CRP of 520. After treatment with intravenous fluid rehydration and analgesia, the knee aspiration grew a Group B Streptococcus, and the patient underwent arthroscopic washout...
January 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28629684/united-states-medical-licensing-examination-and-american-board-of-pediatrics-certification-examination-results-does-the-residency-program-contribute-to-trainee-achievement
#4
Thomas R Welch, Brad G Olson, Elizabeth Nelsen, Gary L Beck Dallaghan, Gloria A Kennedy, Ann Botash
OBJECTIVE: To determine whether training site or prior examinee performance on the US Medical Licensing Examination (USMLE) step 1 and step 2 might predict pass rates on the American Board of Pediatrics (ABP) certifying examination. STUDY DESIGN: Data from graduates of pediatric residency programs completing the ABP certifying examination between 2009 and 2013 were obtained. For each, results of the initial ABP certifying examination were obtained, as well as results on National Board of Medical Examiners (NBME) step 1 and step 2 examinations...
June 16, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28629085/design-of-a-hybrid-biomaterial-for-tissue-engineering-biopolymer-scaffold-integrated-with-an-autologous-hydrogel-carrying-mesenchymal-stem-cells
#5
Caroline R Weinstein-Oppenheimer, Donald I Brown, Rodrigo Coloma, Patricio Morales, Mauricio Reyna-Jeldes, María J Díaz, Elizabeth Sánchez, Cristian A Acevedo
Biologically active biomaterials as biopolymers and hydrogels have been used in medical applications providing favorable results in tissue engineering. In this research, a wound dressing device was designed by integration of an autologous clot hydrogel carrying mesenchymal stem-cells onto a biopolymeric scaffold. This hybrid biomaterial was tested in-vitro and in-vivo, and used in a human clinical case. The biopolymeric scaffold was made with gelatin, chitosan and hyaluronic acid, using a freeze-drying method...
October 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28626154/medical-examination-cancer-screening-and-health-information-channels-of-people-with-sight-impairment-a-survey-of-the-resisters-of-a-braille-library-or-a-sight-impairment-support-group
#6
Chikako Yamaki, Tomoko Takayama
No abstract text is available yet for this article.
2017: [Nihon Kōshū Eisei Zasshi] Japanese Journal of Public Health
https://www.readbyqxmd.com/read/28622914/association-of-resistance-exercise-independent-of-and-combined-with-aerobic-exercise-with-the-incidence-of-metabolic-syndrome
#7
Esmée A Bakker, Duck-Chul Lee, Xuemei Sui, Enrique G Artero, Jonatan R Ruiz, Thijs M H Eijsvogels, Carl J Lavie, Steven N Blair
OBJECTIVE: To determine the association of resistance exercise, independent of and combined with aerobic exercise, with the risk of development of metabolic syndrome (MetS). PATIENTS AND METHODS: The study cohort included adults (mean ± SD age, 46±9.5 years) who received comprehensive medical examinations at the Cooper Clinic in Dallas, Texas, between January 1, 1987, and December, 31, 2006. Exercise was assessed by self-reported frequency and minutes per week of resistance and aerobic exercise and meeting the US Physical Activity Guidelines (resistance exercise ≥2 d/wk; aerobic exercise ≥500 metabolic equivalent min/wk) at baseline...
June 12, 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28617355/-an-analysis-of-the-prevalence-and-risk-factors-of-multiple-sclerosis-in-the-republic-of-ingushetia
#8
Z A Goncharova, R M Uzhakhov
AIM: To determine epidemiological characteristics and factors related to the development of multiple sclerosis (MS) in the population of the Republic of Ingushetia in 2013-2016. MATERIAL AND METHODS: A study was carried out in several clinical settings of the Republic of Ingushetia. A special medical form developed for the study was completed by patients. Medical examination of patients was performed as well. Statistical methods were used for data analysis. RESULTS AND CONCLUSION: A significant variation of MS prevalence was seen...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28612566/-latent-class-analysis-of-health-seeking-behaviors-for-children-in-floating-populations-in-sichuan
#9
Cheng-Han Xiao, Yang Yang, Xiao Ma
OBJECTIVES: To understand the characteristics associated with health care seeking behaviors for children in floating populations. METHODS: A stratified multi-stage sampling strategy with PPS method was employed to select 1 943 children aging 0-7 yr. in the floating populations in Sichuan province, which included 605 flowing out, 468 left-at-home, 822 migrated inhabitants, and 48 returned. Latent class analysis (LCA) was performed to establish potential feature classifications for their use of child health care service (physical examination card, free medical examination, vaccination certificate and immunization) ...
January 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28611885/american-association-for-emergency-psychiatry-task-force-on-medical-clearance-of-adult-psychiatric-patients-part-ii-controversies-over-medical-assessment-and-consensus-recommendations
#10
REVIEW
Michael P Wilson, Kimberly Nordstrom, Eric L Anderson, Anthony T Ng, Leslie S Zun, Jennifer M Peltzer-Jones, Michael H Allen
INTRODUCTION: The emergency medical evaluation of psychiatric patients presenting to United States emergency departments (ED), usually termed "medical clearance," often varies between EDs. A task force of the American Association for Emergency Psychiatry (AAEP), consisting of physicians from emergency medicine, physicians from psychiatry and a psychologist, was convened to form consensus recommendations for the medical evaluation of psychiatric patients presenting to U.S.EDs. METHODS: The task force reviewed existing literature on the topic of medical evaluation of psychiatric patients in the ED and then combined this with expert consensus...
June 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28609369/prevalence-of-pancreatic-cystic-lesions-is-associated-with-diabetes-mellitus-and-obesity-an-analysis-of-5296-individuals-who-underwent-a-preventive-medical-examination
#11
Suguru Mizuno, Hiroyuki Isayama, Yousuke Nakai, Takeharu Yoshikawa, Kazunaga Ishigaki, Saburo Matsubara, Natsuyo Yamamoto, Hideaki Ijichi, Keisuke Tateishi, Minoru Tada, Naoto Hayashi, Kazuhiko Koike
OBJECTIVES: Pancreatic cystic lesions (PCLs) are considered precursors of pancreatic cancer. Diabetes mellitus (DM) and obesity are known as risk factors for pancreatic cancer. We investigated the prevalence of PCLs in the general population and the relationship between PCLs and DM/obesity. METHODS: This cross-sectional analysis included 5296 individuals who underwent a preventive medical examination between October 2006 and June 2013 at our institution. Magnetic resonance imaging, including magnetic resonance cholangiopancreatography, was performed using a 3...
July 2017: Pancreas
https://www.readbyqxmd.com/read/28604832/insects-and-associated-arthropods-analyzed-during-medicolegal-death-investigations-in-harris-county-texas-usa-january-2013-april-2016
#12
Michelle R Sanford
The application of insect and arthropod information to medicolegal death investigations is one of the more exacting applications of entomology. Historically limited to homicide investigations, the integration of full time forensic entomology services to the medical examiner's office in Harris County has opened up the opportunity to apply entomology to a wide variety of manner of death classifications and types of scenes to make observations on a number of different geographical and species-level trends in Harris County, Texas, USA...
2017: PloS One
https://www.readbyqxmd.com/read/28601512/epidemiology-of-fentanyl-involved-drug-overdose-deaths-a-geospatial-retrospective-study-in-rhode-island-usa
#13
Brandon D L Marshall, Maxwell S Krieger, Jesse L Yedinak, Patricia Ogera, Priya Banerjee, Nicole E Alexander-Scott, Josiah D Rich, Traci C Green
BACKGROUND: We conducted an epidemiological investigation of fentanyl and non-fentanyl overdose deaths in Rhode Island to inform overdose prevention efforts. METHODS: All drug overdose deaths occurring in Rhode Island between January 1, 2014 and September 30, 2016 were included. Overdose circumstances and decedent characteristics were ascertained from medical examiner files. Toxicological reports provided quantification of fentanyl and metabolites. ArcGIS was used to map exact overdose locations...
June 7, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28598715/responding-to-a-suicide-death-the-role-of-first-responders
#14
Kenneth Norton
Effective response by first responders in the immediate aftermath of a suicide death can play a critical role in reducing risk and promoting healing for family, friends and the larger community by helping people who are newly bereaved to cope with the immediate crisis, created by the death. They also can lay the foundation for the difficult journey of mourning and healing that must follow. Stressing the importance of a comprehensive and coordinated community response to suicide, this article addresses the principles and practices that are called for in the Guidelines by highlighting four distinct first responder communities: law enforcement and emergency medical services; medical examiners; funeral professionals; and clergy and faith leaders...
June 9, 2017: Death Studies
https://www.readbyqxmd.com/read/28592711/occupational-violence-in-pregnant-women-in-brazil-a-sample-of-cases-in-the-labor-court
#15
Bárbara de Oliveira Turatti, Rodrigo Otávio Moretti-Pires
Brazilian women are still a recurring target of discrimination in the workplace, facing violence related to gender relations and moral harassment, especially when they are pregnant. When the worker perceives discriminatory acts and attitudes or any violation of the rights guaranteed by law, she may appeal to the Labor Court to initiate legal action. This in turn exposes the worker to a number of issues, such as workplace persecution and future dismissal. The rights of pregnant women to temporary stability, free time for medical examinations, change of duties and maternity leave contrast with the usurpation of the administration's workforce...
June 7, 2017: Journal of Occupational Health
https://www.readbyqxmd.com/read/28592099/-study-of-the-association-between-polymorphism-of-persistent-obesity-human-leptin-gene-leptin-receptor-gene-and-molecular-subtypes-of-breast-cancer
#16
X L Yuan, Z P Xu, C R Liu, L P Yan, P Tao, P Xiong, Q Li, M Zhou, H Li, M Zhao, J Y Li
Objectives: To explore the association between the polymorphism of persistent obesity and genetic variations in the LEP (human leptin gene, LEP) and LEPR (leptin receptor gene, LEPR) genes and different molecular subtypes of breast cancer. Methods: All 703 female patients of breast cancer diagnosed by histopathology in the Sichuan Cancer Hospital or the West China Hospital, excluding patients with metastatic breast cancer or mental disease, were selected as cases from April 2014 to May 2015. At the same time, 805 healthy women received physical examination in medical examination center of Sichuan People Hospital or Shuangliu maternal and child health care hospital, excluding those with therioma, breast disease, and mental disease, were enrolled in control group...
June 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28588667/physical-inactivity-associated-with-the-risk-of-non-communicable-diseases-in-japanese-working-mothers-with-young-children-a-cross-sectional-study-in-nagano-city-japan
#17
Yoshio Suzuki, Keishoku Sakuraba, Tokiko Shinjo, Asako Maruyama-Nagao, Atsuko Nakaniida, Haruka Kadoya, Marika Shibata, Takehisa Matsukawa, Hiroaki Itoh, Kazuhito Yokoyama
Physical activity helps to prevent the development of chronic non-communicable diseases. However, childbearing generally reduces parents' level of physical activity, particularly in mothers. Therefore, mothers with young children generally have lower levels of physical activity and have a higher risk of developing non-communicable diseases. The aim of the present study was to examine this risk in Japanese working mothers with young children. A cross-sectional study was conducted in four nursery schools in Nagano city, Japan...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28586383/at-risk-and-intervention-thresholds-of-occupational-stress-using-a-visual-analogue-scale
#18
Frédéric Dutheil, Bruno Pereira, Farès Moustafa, Geraldine Naughton, François-Xavier Lesage, Céline Lambert
BACKGROUND: The visual analogue scale (VAS) is widely used in clinical practice by occupational physicians to assess perceived stress in workers. However, a single cut-off (black-or-white decision) inadequately discriminates between workers with and without stress. We explored an innovative statistical approach to distinguish an at-risk population among stressed workers, and to establish a threshold over which an action is urgently required, via the use of two cut-offs. METHODS: Participants were recruited during annual work medical examinations by a random sample of workers from five occupational health centres...
2017: PloS One
https://www.readbyqxmd.com/read/28580830/thrombocytopenia-and-gba-gene-mutation-in-a-patient-with-adult-type-1-gaucher-disease
#19
Lagen Wan, Hong Wu, Fuyuan Xie, Yijun Nie
A 38-year-old female patient was diagnosed with anemia for 3 years. Medical examination showed slight splenomegaly (250 × 62 mm), thrombocytopenia (platelets 51 × 10(9)/L), anemia (Hb levels 107 g/L), and β-glucocerebrosidase activity (GBA) in leukocytes was lower than normal. Microscopic findings of bone marrow smear demonstrated that Gaucher cells in bone marrow and periodic acid-Schiff staining of them were positive. Sequencing of GBA genomic and cDNA identified one novel homozygous mutation, c.484A> G (p...
June 5, 2017: Platelets
https://www.readbyqxmd.com/read/28575559/-syndrome-of-emotional-burnout-among-women-physicians-elderly
#20
V S Myakotnykh, T A Borovkova
The article presents the results of a comparative study of clinical symptoms of syndrome of emotional burnout among 84 working in the specialty physician of older women and 48 officially ceasing operations in this specialty. The findings suggest that burnout can take place among representatives of older age and more it is continued, provided professional activities. The cessation of the work activities leads to stress, often with the subsequent development post-traumatic stress disorder and stress-induced diseases...
2017: Advances in Gerontology, Uspekhi Gerontologii
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