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Andrew Pearle

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https://www.readbyqxmd.com/read/29054315/cord-topographical-anatomy-and-its-role-in-evaluating-intramedullary-lesions
#1
REVIEW
James Andrew Spain, Scott Cressman, Horia Marin, Suresh C Patel, John J Corrigan, Brent Griffith
Intramedullary spinal lesions present a wide differential diagnosis including infectious, inflammatory, traumatic, ischemic, benign, or malignant neoplastic etiologies. Using knowledge of anatomy and physiology within the spinal cord, many similar appearing entities can be parsed into a prioritized differential. The purpose of this article is to review anatomy and pathophysiology of the spinal cord, with subsequent discussion of how this knowledge can be used to differentiate several similar appearing intramedullary pathologic processes...
September 18, 2017: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/29049055/oxidized-regenerated-cellulose-collagen-dressings-review-of-evidence-and-recommendations
#2
Stephanie Wu, Andrew J Applewhite, Jeffrey Niezgoda, Robert Snyder, Jayesh Shah, Breda Cullen, Gregory Schultz, Janis Harrison, Rosemary Hill, Melania Howell, Marcus Speyrer, Howard Utra, Jean de Leon, Wayne Lee, Terry Treadwell
OBJECTIVE: Healthcare systems are being challenged to manage increasing numbers of nonhealing wounds. Wound dressings are one of the first lines of defense in wound management, and numerous options exist. The oxidized regenerated cellulose (ORC)/collagen dressing may offer healthcare providers a robust and cost-effective tool for use in a variety of wounds. DESIGN: A multidisciplinary panel meeting was convened to discuss the use of ORC/collagen dressings in wound care and provide practice recommendations...
November 2017: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/28983215/mid-term-outcomes-of-metal-backed-unicompartmental-knee-arthroplasty-show-superiority-to-all-polyethylene-unicompartmental-and-total-knee-arthroplasty
#3
Jelle P van der List, Laura J Kleeblad, Hendrik A Zuiderbaan, Andrew D Pearle
BACKGROUND: Two commonly used tibial designs for unicompartmental knee arthroplasty (UKA) are all-polyethylene "inlay" and metal-backed "onlay" components. Biomechanical studies showed that the metal baseplate in onlay designs better distributes forces over the tibia but studies failed to show differences in functional outcomes between both designs at mid-term follow-up. Furthermore, no studies have compared both designs with total knee arthroplasty (TKA). QUESTIONS/PURPOSES: The goal of this study was to compare outcomes of inlay UKA and onlay UKA at mid-term follow-up and compare these with TKA outcomes...
October 2017: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
https://www.readbyqxmd.com/read/28922347/pearl-millet-genome-sequence-provides-a-resource-to-improve-agronomic-traits-in-arid-environments
#4
Rajeev K Varshney, Chengcheng Shi, Mahendar Thudi, Cedric Mariac, Jason Wallace, Peng Qi, He Zhang, Yusheng Zhao, Xiyin Wang, Abhishek Rathore, Rakesh K Srivastava, Annapurna Chitikineni, Guangyi Fan, Prasad Bajaj, Somashekhar Punnuri, S K Gupta, Hao Wang, Yong Jiang, Marie Couderc, Mohan A V S K Katta, Dev R Paudel, K D Mungra, Wenbin Chen, Karen R Harris-Shultz, Vanika Garg, Neetin Desai, Dadakhalandar Doddamani, Ndjido Ardo Kane, Joann A Conner, Arindam Ghatak, Palak Chaturvedi, Sabarinath Subramaniam, Om Parkash Yadav, Cécile Berthouly-Salazar, Falalou Hamidou, Jianping Wang, Xinming Liang, Jérémy Clotault, Hari D Upadhyaya, Philippe Cubry, Bénédicte Rhoné, Mame Codou Gueye, Ramanjulu Sunkar, Christian Dupuy, Francesca Sparvoli, Shifeng Cheng, R S Mahala, Bharat Singh, Rattan S Yadav, Eric Lyons, Swapan K Datta, C Tom Hash, Katrien M Devos, Edward Buckler, Jeffrey L Bennetzen, Andrew H Paterson, Peggy Ozias-Akins, Stefania Grando, Jun Wang, Trilochan Mohapatra, Wolfram Weckwerth, Jochen C Reif, Xin Liu, Yves Vigouroux, Xun Xu
Pearl millet [Cenchrus americanus (L.) Morrone] is a staple food for more than 90 million farmers in arid and semi-arid regions of sub-Saharan Africa, India and South Asia. We report the ∼1.79 Gb draft whole genome sequence of reference genotype Tift 23D2B1-P1-P5, which contains an estimated 38,579 genes. We highlight the substantial enrichment for wax biosynthesis genes, which may contribute to heat and drought tolerance in this crop. We resequenced and analyzed 994 pearl millet lines, enabling insights into population structure, genetic diversity and domestication...
October 2017: Nature Biotechnology
https://www.readbyqxmd.com/read/28697861/regional-femoral-and-tibial-radiolucency-in-cemented-unicompartmental-knee-arthroplasty-and-the-relationship-to-functional-outcomes
#5
Laura J Kleeblad, Jelle P van der List, Hendrik A Zuiderbaan, Andrew D Pearle
BACKGROUND: Femoral and tibial radiolucent lines (RLL) after unicompartmental knee arthroplasty (UKA) can be categorized in physiological and pathological radiolucencies. Although physiological tibial radiolucency is assessed extensively in literature, studies reporting femoral radiolucency are lacking. Therefore, a retrospective study was performed to assess physiological femoral RLL and its relationship to short-term functional outcomes. METHODS: A total of 352 patients were included who underwent robotic-assisted medial UKA surgery and received a fixed-bearing metal-backed cemented medial UKA...
November 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28682711/-i-have-strong-hopes-for-the-future-time-orientations-and-resilience-among-canadian-indigenous-youth
#6
Andrew R Hatala, Tamara Pearl, Kelley Bird-Naytowhow, Andrew Judge, Erynne Sjoblom, Linda Liebenberg
In this article, we demonstrate how concepts of time and the future inform processes of resilience among Indigenous adolescents within an urban Canadian context. This study employed a modified grounded theory methodology by conducting 38 qualitative interviews with 28 Indigenous youth (ages 15-25) over the course of 1 year. The analysis revealed complex processes of and navigations between moments of distress and strategies for resilience. The distressing contexts in which Indigenous youth often find themselves can impact the development of their concepts of time and limit their abilities to conceptualize a future...
July 2017: Qualitative Health Research
https://www.readbyqxmd.com/read/28628728/characterizing-the-detection-threshold-for-optical-imaging-in-surgical-oncology
#7
Andrew C Prince, Aditi Jani, Melissa Korb, Kiranya E Tipirneni, Benjamin B Kasten, Eben L Rosenthal, Jason M Warram
BACKGROUND AND OBJECTIVES: Optical imaging to guide cancer resections is rapidly transitioning into the operating room. However, the sensitivity of this technique to detect subclinical disease is yet characterized. The purpose of this study was to determine the minimum range of cancer cells that can be detected by antibody-based fluorescence imaging. METHODS: 2LMP (breast), COLO-205 (colon), MiaPaca-2 (pancreas), and SCC-1 (head and neck) cells incubated in vitro with cetuximab-IRDye800CW (dose range 8...
June 19, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28601764/maternal-perchlorate-exposure-in-pregnancy-and-altered-birth-outcomes
#8
Rainbow Rubin, Michelle Pearl, Martin Kharrazi, Benjamin C Blount, Mark D Miller, Elizabeth N Pearce, Liza Valentin-Blasini, Gerald DeLorenze, Jane Liaw, Andrew N Hoofnagle, Craig Steinmaus
BACKGROUND: At high medicinal doses perchlorate is known to decrease the production of thyroid hormone, a critical factor for fetal development. In a large and uniquely exposed cohort of pregnant women, we recently identified associations between environmental perchlorate exposures and decreased maternal thyroid hormone during pregnancy. Here, we investigate whether perchlorate might be associated with birthweight or preterm birth in the offspring of these women. METHODS: Maternal urinary perchlorate, serum thyroid hormone concentrations, birthweight, gestational age, and urinary nitrate, thiocyanate, and iodide were collected in 1957 mother-infant pairs from San Diego County during 2000-2003, a period when the county's water supply was contaminated with perchlorate...
October 2017: Environmental Research
https://www.readbyqxmd.com/read/28592667/motorboat-noise-impacts-parental-behaviour-and-offspring-survival-in-a-reef-fish
#9
Sophie L Nedelec, Andrew N Radford, Leanne Pearl, Brendan Nedelec, Mark I McCormick, Mark G Meekan, Stephen D Simpson
Anthropogenic noise is a pollutant of international concern, with mounting evidence of disturbance and impacts on animal behaviour and physiology. However, empirical studies measuring survival consequences are rare. We use a field experiment to investigate how repeated motorboat-noise playback affects parental behaviour and offspring survival in the spiny chromis (Acanthochromis polyacanthus), a brooding coral reef fish. Repeated observations were made for 12 days at 38 natural nests with broods of young. Exposure to motorboat-noise playback compared to ambient-sound playback increased defensive acts, and reduced both feeding and offspring interactions by brood-guarding males...
June 14, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28523513/erratum-to-high-interspecimen-variability-in-engagement-of-the-anterolateral-ligament-an-in-vitro-cadaveric-study
#10
Robert N Kent, James F Boorman-Padgett, Ran Thein, Jelle P van der List, Danyal H Nawabi, Thomas L Wickiewicz, Carl W Imhauser, Andrew D Pearle
No abstract text is available yet for this article.
October 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28477147/high-interspecimen-variability-in-engagement-of-the-anterolateral-ligament-an-in-vitro-cadaveric-study
#11
REVIEW
Robert N Kent, James F Boorman-Padgett, Ran Thein, Jelle P van der List, Danyal H Nawabi, Thomas L Wickiewicz, Carl W Imhauser, Andrew D Pearle
BACKGROUND: Anterolateral ligament (ALL) reconstruction as an adjunct to anterior cruciate ligament (ACL) reconstruction remains a subject of clinical debate. This uncertainty may be driven in part by a lack of knowledge regarding where, within the range of knee motion, the ALL begins to carry force (engages). QUESTIONS/PURPOSES: (1) Does the ALL engage in the ACL-intact knee; and (2) where within the range of anterior tibial translation occurring in the ACL-sectioned knee does the ALL engage? METHODS: A robotic manipulator was used to measure anterior tibial translation, ACL forces, and ALL forces in 10 fresh-frozen cadaveric knees (10 donors; mean age, 41 ± 16 years; range, 20-64 years; eight male) in response to applied multiplanar torques...
May 5, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28435507/blog-and-podcast-watch-orthopedic-emergencies
#12
Andrew Grock, Salim Rezaie, Anand Swaminathan, Alice Min, Kaushal H Shah, Michelle Lin
INTRODUCTION: The WestJEM Blog and Podcast Watch presents high quality open-access educational blogs and podcasts in emergency medicine (EM) based on the ongoing ALiEM Approved Instructional Resources (AIR) and AIR-Professional series. Both series critically appraise resources using an objective scoring rubric. This installment of the Blog and Podcast Watch highlights the topic of orthopedic emergencies from the AIR series. METHODS: The AIR series is a continuously building curriculum that follows the Council of Emergency Medicine Residency Directors (CORD) annual testing schedule...
April 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28409106/open-bankart-revisited
#13
Ryan P Coughlin, Andrew Crapser, Kyrstin Coughlin, Larry P Coughlin
The surgical treatment of anterior shoulder instability can present a dilemma. Historically, an open Bankart repair was the benchmark solution. Over the last decade as surgeons became more arthroscopically savvy, the pendulum swung and a paradigm shift occurred. However, more recent studies have challenged this trend and, subsequently, revived interest in open repair. Thus, we feel it is critical to provide a more contemporary stepwise description of a procedure that has become essentially abandoned. The goal is to provide tips and pearls to achieve optimal exposure and, ultimately, a robust repair for a notoriously challenging operation...
February 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28355672/ligamentous-reconstruction-of-the-knee-what-orthopaedic-surgeons-want-radiologists-to-know
#14
Andrew G Geeslin, Matthew G Geeslin, Robert F LaPrade
Knee ligament injuries are common, and treatment methods are continually evolving. Accurate clinical diagnosis with imaging confirmation is critical to support appropriate treatment. Several imaging pearls allow for improved recognition of injuries. Stress radiographs may be obtained to quantify knee laxity. Magnetic resonance imaging allows assessment of the complex anatomy of the knee and has excellent sensitivity and specificity for many injuries.
April 2017: Seminars in Musculoskeletal Radiology
https://www.readbyqxmd.com/read/28355083/systematic-review-of-outcomes-reporting-in-professional-baseball-a-call-for-increased-validation-and-consistency
#15
Jelle P van der List, Christopher L Camp, Alec L Sinatro, Joshua S Dines, Andrew D Pearle
BACKGROUND: Historically, treatment efficacy of professional baseball injuries has been determined by assessing the return-to-play (RTP) rate or using patient-reported functional outcomes scores; however, these methods may not be sensitive and specific enough for elite athletes. As a consequence, performance-based statistics are increasingly being reported in the medical literature. PURPOSE: To (1) assess how treatment efficacy is currently reported in professional baseball players; (2) examine the variability in the reporting of these measures in terms of frequency, length of time followed, and units of measure; and (3) identify any attempts to validate these performance-based statistics...
March 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28298053/passive-anterior-tibial-subluxation-in-the-setting-of-anterior-cruciate-ligament-injuries-a-comparative-analysis-of-ligament-deficient-states
#16
Lucas S McDonald, Jelle P van der List, Kristofer J Jones, Hendrik A Zuiderbaan, Joseph T Nguyen, Hollis G Potter, Andrew D Pearle
BACKGROUND: Static anterior tibial subluxation after an anterior cruciate ligament (ACL) injury highlights the abnormal relationship between the tibia and femur in patients with ACL insufficiency, although causal factors including injuries to secondary stabilizers or the time from injury to reconstruction have not been examined. PURPOSE: To determine static relationships between the tibia and femur in patients with various states of ACL deficiency and to identify factors associated with anterior tibial subluxation...
June 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28210366/blog-and-podcast-watch-cutaneous-emergencies
#17
Andrew Grock, Eric J Morley, Lynn Roppolo, Jay Khadpe, Felix Ankel, Michelle Lin
INTRODUCTION: The WestJEM Blog and Podcast Watch presents high quality open-access educational blogs and podcasts in emergency medicine (EM) based on the ongoing Academic Life in Emergency Medicine (ALiEM) Approved Instructional Resources (AIR) and AIR-Professional series. Both series critically appraise resources using an objective scoring rubric. This installment of the Blog and Podcast Watch highlights the topic of cutaneous emergencies from the AIR series. METHODS: The AIR series is a continuously building curriculum that follows the Council of Emergency Medicine Residency Directors (CORD) annual testing schedule...
February 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28185777/survivorship-and-patient-satisfaction-of-robotic-assisted-medial-unicompartmental-knee-arthroplasty-at-a-minimum-two-year-follow-up
#18
Andrew D Pearle, Jelle P van der List, Lily Lee, Thomas M Coon, Todd A Borus, Martin W Roche
BACKGROUND: Successful clinical outcomes following unicompartmental knee arthroplasty (UKA) depend on lower limb alignment, soft tissue balance and component positioning, which can be difficult to control using manual instrumentation. Although robotic-assisted surgery more reliably controls these surgical factors, studies assessing outcomes of robotic-assisted UKA are lacking. Therefore, a prospective multicenter study was performed to assess outcomes of robotic-assisted UKA. METHODS: A total of 1007 consecutive patients (1135 knees) underwent robotic-assisted medial UKA surgery from six surgeons at separate institutions between March 2009 and December 2011...
March 2017: Knee
https://www.readbyqxmd.com/read/28086751/quantifying-predictors-for-the-spatial-diffusion-of-avian-influenza-virus-in-china
#19
Lu Lu, Andrew J Leigh Brown, Samantha J Lycett
BACKGROUND: Avian influenza virus (AIV) causes both severe outbreaks and endemic disease among poultry and has caused sporadic human infections in Asia, furthermore the routes of transmission in avian species between geographic regions can be numerous and complex. Using nucleotide sequences from the internal protein coding segments of AIV, we performed a Bayesian phylogeographic study to uncover regional routes of transmission and factors predictive of the rate of viral diffusion within China...
January 13, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/28005121/limited-incision-knotless-achilles-tendon-repair
#20
Andrew R Hsu
Acute midsubstance Achilles tendon ruptures, which are increasingly common among athletes, can result in significant functional limitations and decreased quality of life when not managed appropriately. The various surgical techniques for treating Achilles ruptures include open repair with Krackow locking sutures, percutaneous repair, and limited-incision repair with suture-passing jigs. Less invasive techniques have been developed to optimize the functional benefits of surgery while reducing delayed wound healing, infection, and other postoperative complications...
November 2016: American Journal of Orthopedics
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