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https://www.readbyqxmd.com/read/27913229/a-single-arm-phase-iii-study-exploring-the-efficacy-and-safety-of-lng-ius-8-a-low-dose-levonorgestrel-intrauterine-contraceptive-system-total-content-13-5-mg-in-an-asia-pacific-population
#1
Guangsheng Fan, Sukho Kang, Mulan Ren, Edith Weisberg, Eeva Lukkari-Lax, Katrin Roth, SoYoung Shin
OBJECTIVE: To evaluate the efficacy and safety of a low-dose levonorgestrel intrauterine system with total content 13.5 mg (average approx. 8 μg/24 h over the first year; LNG-IUS 8; Jaydess®) in an Asia-Pacific population. STUDY DESIGN: An open-label, single-arm Phase III study conducted at 25 centers in China, Australia, and Korea assessed LNG-IUS 8 use over 3 years in nulliparous and parous women (N=1114) aged 18-40 years with regular menstrual cycles (21-35 days)...
November 29, 2016: Contraception
https://www.readbyqxmd.com/read/27909912/identification-and-characterization-of-the-lysine-rich-matrix-protein-family-in-pinctada-fucata-indicative-of-roles-in-shell-formation
#2
Jian Liang, Jun Xie, Jing Gao, Chao-Qun Xu, Yi Yan, Gan-Chu Jia, Liang Xiang, Li-Ping Xie, Rong-Qing Zhang
Mantle can secret matrix proteins playing key roles in regulating the process of shell formation. The genes encoding lysine-rich matrix proteins (KRMPs) are one of the most highly expressed matrix genes in pearl oysters. However, the expression pattern of KRMPs is limited and the functions of them still remain unknown. In this study, we isolated and identified six new members of lysine-rich matrix proteins, rich in lysine, glycine and tyrosine, and all of them are basic matrix proteins. Combined with four members of the KRMPs previously reported, all these proteins can be divided into three subclasses according to the results of phylogenetic analyses: KRMP1-3 belong to subclass KPI, KRMP4-5 belong to KPII, and KRMP6-10 belong to KPIII...
December 2, 2016: Marine Biotechnology
https://www.readbyqxmd.com/read/27909666/arthroscopic-reduction-and-internal-fixation-for-pipkin-type-i-femoral-head-fracture-technical-note
#3
Aditya Kekatpure, Taesoo Ahn, Soong Joon Lee, Mi Youn Jeong, Jae Suk Chang, Pil Whan Yoon
Femoral head fractures after posterior dislocation of the hip are uncommon and are conventionally treated by an open method. Hip arthroscopy can be a valuable treatment option for the management of femoral head fractures. Arthroscopy allows for a less invasive option when compared with arthrotomy and can allow faster recovery with minimal soft-tissue injury. We describe the arthroscopic reduction and internal fixation of Pipkin type I femoral head fractures with a detailed stepwise description of the surgical technique, including technical pearls and pitfalls, potential complications, and advantages and disadvantages...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/27907178/characteristics-of-phytoplankton-biomass-primary-production-and-community-structure-in-the-modaomen-channel-pearl-river-estuary-with-special-reference-to-the-influence-of-saltwater-intrusion-during-neap-and-spring-tides
#4
Weihua Zhou, Jie Gao, Jianzu Liao, Ronggui Shi, Tao Li, Yajuan Guo, Aimin Long
In recent decades, increasing frequency and intensity of saltwater intrusion in the Modaomen Channel has threatened the freshwater supply in the surrounding cities of the Pearl River Estuary, and ulteriorly changed the environmental conditions of the estuarine waters. Phytoplankton biomass, primary production (PP) and species composition, as well as hydrological and chemical parameters were examined along a downstream transect in the Modaomen Channel during neap tide (NT) and spring tide (ST), when a strong saltwater intrusion event occurred in late September, 2011...
2016: PloS One
https://www.readbyqxmd.com/read/27906664/pearls-oy-sters-plasma-cell-meningitis-an-uncommon-complication-of-multiple-myeloma
#5
Neville Jadeja, Krishna Nalleballe, Jerome Graber
No abstract text is available yet for this article.
November 15, 2016: Neurology
https://www.readbyqxmd.com/read/27904547/the-effect-of-vitamin-d-administration-on-serum-leptin-and-adiponectin-levels-in-end-stage-renal-disease-patients-on-hemodialysis-with-vitamin-d-deficiency-a-placebo-controlled-double-blind-clinical-trial
#6
Afsoon Emami Naini, Sahar Vahdat, Zahra Parin Hedaiati, Safoura Shahzeidi, Amir Hossein Pezeshki, Hamid Nasri
BACKGROUND: The prevalence of vitamin D deficiency is higher in end-stage renal disease (ESRD) patients compared to healthy populations. This deficiency could lead to several complications with different mechanisms and might result in reduced survival in patients. Leptin and adiponectin are messenger proteins with endocrine secretion from adipocytes and various effects in cellular mechanisms. The goal of this study was to find the effect of vitamin D administration on serum levels of leptin and adiponectin in ESRD patients...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27902850/biomechanical-comparison-of-2-veterinary-locking-plates-to-monocortical-screw-polymethylmethacrylate-fixation-in-canine-cadaveric-cervical-vertebral-column
#7
Bianca F Hettlich, Geoffrey T Fosgate, Alan S Litsky
OBJECTIVE: To compare the biomechanical properties of 2 veterinary locking plates and monocortical screws/polymethylmethacrylate (PMMA) fixation in canine cadaveric cervical vertebral columns. STUDY DESIGN: Biomechanical cadaveric study. MATERIALS: Nineteen cervical vertebral columns (C2-C7) from large breed, skeletally mature, canine cadavers were used. A cortical ring was placed as a disk spacer at C4-C5 in all specimens. Seven vertebral columns were plated at C4-C5 with two 4-hole, 3...
November 30, 2016: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/27900722/atmospheric-deposition-of-pbdes-and-dps-in-dongjiang-river-basin-south-china
#8
Xiaowei Wu, Yan Wang, Minmin Hou, Chunling Luo, Hongxia Zhao, Gan Zhang
The atmospheric deposition fluxes of polybrominated diphenyl ethers (PBDEs) and Dechlorane Plus (DPs) in Dongjiang River Basin of the Pearl River Delta in South China were investigated during winter and summer, respectively. The total deposition fluxes varied from 4.74 to 27.0 ng/m(2)/day for PBDEs and 8.77 to 206 ng/m(2)/day for DPs, respectively. The fractions of anti-DP to the total DPs (f anti) varied from 0.28 to 0.63 (mean = 0.43 ± 0.06), i.e., generally lower than those in commercial products, which might be attributed to the different environmental fates of the two isomers...
November 30, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27898821/development-of-a-high-density-linkage-map-and-tagging-leaf-spot-resistance-in-pearl-millet-using-genotyping-by-sequencing-markers
#9
Somashekhar M Punnuri, Jason G Wallace, Joseph E Knoll, Katie E Hyma, Sharon E Mitchell, Edward S Buckler, Rajeev K Varshney, Bharat P Singh
Pearl millet [ (L.) R. Br; also (L.) Morrone] is an important crop throughout the world but better genomic resources for this species are needed to facilitate crop improvement. Genome mapping studies are a prerequisite for tagging agronomically important traits. Genotyping-by-sequencing (GBS) markers can be used to build high-density linkage maps, even in species lacking a reference genome. A recombinant inbred line (RIL) mapping population was developed from a cross between the lines 'Tift 99DB' and 'Tift 454'...
July 2016: Plant Genome
https://www.readbyqxmd.com/read/27896657/performing-the-difficult-cholecystectomy-using-combined-endoscopic-and-robotic-techniques-how-i-do-it
#10
Deepa Magge, Jennifer Steve, Stephanie Novak, Adam Slivka, Mellissa Hogg, Amer Zureikat, Herbert J Zeh
Laparoscopic cholecystectomy is the standard of care for cholelithiasis as well as cholecystitis. However, in the setting of Mirizzi syndrome or gangrenous cholecystitis where the critical view cannot be ascertained, subtotal cholecystectomy may be necessary. Using the robot-assisted approach, difficult cholecystectomies can be performed upfront without need for partial cholecystectomy. Even in the setting of Mirizzi syndrome where severe scarring and fibrosis are evident, definitive cholecystectomy and takedown of the cholechystocholedochal fistula can be performed in a safe and feasible fashion following successful endoscopic common bile duct stent placement...
November 28, 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/27896419/effects-of-enamel-sealing-on-shear-bond-strength-and-the-adhesive-remnant-index-study-of-three-fluoride-releasing-adhesives-in-combination-with-metal-and-ceramic-brackets
#11
Elisabeth Hofmann, Laura Elsner, Ursula Hirschfelder, Thomas Ebert, Sebastian Hanke
OBJECTIVES: Selected combinations of materials were used to create tooth-adhesive-bracket complexes to evaluate shear bond strength (SBS) and the adhesive remnant index (ARI) with regard to enamel sealing. METHODS: Four adhesive systems also appropriate for use as enamel sealants were combined with four bracket types, resulting in 16 adhesive-bracket combinations, each of which was tested on 15 permanent bovine incisors. Sealant-adhesives included two recently introduced fluoride-releasing systems (Riva bond LC(®) and go!(®)), one established primer (Opal(®) Seal™), and one commonly used adhesive as control (Transbond™ XT)...
November 28, 2016: Journal of Orofacial Orthopedics, Fortschritte der Kieferorthopädie
https://www.readbyqxmd.com/read/27896385/pictorial-review-the-pearls-and-pitfalls-of-the-radiological-manifestations-of-gallstone-ileus
#12
REVIEW
Phei Shan Chuah, John Curtis, Nikhil Misra, Dina Hikmat, Sumita Chawla
We present a pictorial review of a range of typical and atypical cases of gallstone ileus (GI), across a wide range of imaging modalities. GI is a complication of gallstone disease causing mechanical intestinal obstruction due to impaction of gallstone in the gastrointestinal tract. The spectrum of presentation can vary enormously, and we highlight the importance of accurate imaging diagnosis of GI especially early use of computed tomography. This will lead to timely and appropriate surgical intervention with the potential avoidance of unnecessary outcomes...
November 28, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27895647/exogenous-trehalose-treatment-enhances-the-activities-of-defense-related-enzymes-and-triggers-resistance-against-downy-mildew-disease-of-pearl-millet
#13
Sharathchandra R Govind, Sudisha Jogaiah, Mostafa Abdelrahman, Hunthrike S Shetty, Lam-Son P Tran
In recent years, diverse physiological functions of various sugars are the subject of investigations. Their roles in signal transduction in plant responses to adverse biotic and abiotic stress conditions have become apparent, and growing scientific evidence has indicated that disaccharides like sucrose and trehalose mediate plant defense responses in similar way as those induced by elicitors against the pathogens. Trehalose is a well-known metabolic osmoregulator, stress-protectant and non-reducing disaccharide existing in a variety of organisms, including fungi, bacteria, and plants...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27890182/imaging-of-perineural-spread-in-head-and-neck-cancer
#14
REVIEW
David Badger, Nafi Aygun
Perineural spread (PNS) of tumor is a recognized pattern of metastasis occurring in the head and neck. Imaging plays a critical role in identifying PNS for adequate staging and treatment planning. Understanding the major branches and pathways of cranial nerves V and VII, key anatomic landmarks, interconnections between these nerves, and pearls and pitfalls of PNS imaging can aid in early detection, appropriate therapy, and the best possible chance for cure.
January 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/27889145/potential-probiotic-pichia-kudriavzevii-strains-and-their-ability-to-enhance-folate-content-of-traditional-cereal-based-african-fermented-food
#15
Anna Greppi, Fabien Saubade, Cristian Botta, Christèle Humblot, Jean-Pierre Guyot, Luca Cocolin
With the aim of selecting starter cultures with interesting probiotic potential and with the ability to produce folate in a food matrix, yeast strains isolated from fermented cereal-based African foods were investigated. A total of 93 yeast strains were screened for their tolerance to pH 2 and 0.3% of bile salts. Pichia kudriavzevii isolates gave the best results. Selected P. kudriavzevii strains were tested for survival to the simulated human digestion and for adhesion to Caco-2 cells. Moreover, presence of folate biosynthesis genes was verified and production of extra and intra-cellular folate determined during growth in culture medium...
April 2017: Food Microbiology
https://www.readbyqxmd.com/read/27889085/impact-of-diurnal-variability-and-meteorological-factors-on-the-pm2-5-aod-relationship-implications-for-pm2-5-remote-sensing
#16
Jianping Guo, Feng Xia, Yong Zhang, Huan Liu, Jing Li, Mengyun Lou, Jing He, Yan Yan, Fu Wang, Min Min, Panmao Zhai
PM2.5 retrieval from space is still challenging due to the elusive relationship between PM2.5 and aerosol optical depth (AOD), which is further complicated by meteorological factors. In this work, we investigated the diurnal cycle of PM2.5 in China, using ground-based PM measurements obtained at 226 sites of China Atmosphere Watch Network during the period of January 2013 to December 2015. Results showed that nearly half of the sites witnessed a PM2.5 maximum in the morning, in contrast to the least frequent occurrence (5%) in the afternoon when strong solar radiation received at the surface results in rapid vertical diffusion of aerosols and thus lower mass concentration...
November 23, 2016: Environmental Pollution
https://www.readbyqxmd.com/read/27886691/pharmacotherapy-pearls-for-the-geriatrician-focus-on-oral-disease-modifying-antirheumatic-drugs-including-newer-agents
#17
REVIEW
Ann J Biehl, James D Katz
Providing safe and effective pharmacotherapy to the geriatric patients with rheumatological disorders is an ongoing struggle for the rheumatologist and geriatrician alike. Cohesive communication and partnership can improve the care of these patients and subvert adverse outcomes. Disease-modifying antirheumatic drugs, including methotrexate, hydroxychloroquine, sulfasalazine, and leflunomide, and the newest oral agent for treatment of rheumatoid arthritis, tofacitinib, have distinctive monitoring and adverse effect profiles...
February 2017: Clinics in Geriatric Medicine
https://www.readbyqxmd.com/read/27886227/impact-of-human-activities-on-subaqueous-topographic-change-in-lingding-bay-of-the-pearl-river-estuary-china-during-1955-2013
#18
Z Y Wu, Yoshiki Saito, D N Zhao, J Q Zhou, Z Y Cao, S J Li, J H Shang, Y Y Liang
Estuaries have been sites of intensive human activities during the past century. Tracing the evolution of subaqueous topography in estuaries on a decadal timescale enables us to understand the effects of human activities on estuaries. Bathymetric data from 1955 to 2010 show that land reclamation decreased the subaqueous area of Lingding Bay, in the Pearl River estuary, by ~170 km(2) and decreased its water volume by 615 × 10(6) m(3), representing a net decrease of 11.2 × 10(6 )m(3) per year and indicating the deposition of approximately 14...
November 25, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27877203/past-and-present-dynamics-of-sorghum-and-pearl-millet-diversity-in-mount-kenya-region
#19
Vanesse Labeyrie, Monique Deu, Yann Dussert, Bernard Rono, Françoise Lamy, Charles Marangu, Dan Kiambi, Caroline Calatayud, Geo Coppens d'Eeckenbrugge, Thierry Robert, Christian Leclerc
Crop populations in smallholder farming systems are shaped by the interaction of biological, ecological, and social processes, occurring on different spatiotemporal scales. Understanding these dynamics is fundamental for the conservation of crop genetic resources. In this study, we investigated the processes involved in sorghum and pearl millet diversity dynamics on Mount Kenya. Surveys were conducted in ten sites distributed along two elevation transects and occupied by six ethnolinguistic groups. Varieties of both species grown in each site were inventoried and characterized using SSR markers...
December 2016: Evolutionary Applications
https://www.readbyqxmd.com/read/27876798/proliferation-of-listeria-monocytogenes-l-form-cells-by-formation-of-internal-and-external-vesicles
#20
Patrick Studer, Titu Staubli, Noémi Wieser, Patrick Wolf, Markus Schuppler, Martin J Loessner
L-forms are cell wall-deficient bacteria that divide through unusual mechanisms, involving dynamic perturbations of the cellular shape and generation of vesicles, independently of the cell-division protein FtsZ. Here we describe FtsZ-independent mechanisms, involving internal and external vesicles, by which Listeria monocytogenes L-forms proliferate. Using micromanipulation of single cells and vesicles, we show that small vesicles are formed by invagination within larger intracellular vesicles, receive cytoplasmic content, and represent viable progeny...
November 23, 2016: Nature Communications
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