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Craniofacial orthopedics

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https://www.readbyqxmd.com/read/27898256/comparative-study-of-the-physiotherapeutic-and-drug-protocol-and-low-level-laser-irradiation-in-the-treatment-of-pain-associated-with-temporomandibular-dysfunction
#1
Marcos Fernando Xisto Braga Cavalcanti, Uoston Holder Silva, Ernesto Cesar Pinto Leal-Junior, Rodrigo A B Lopes-Martins, Rodrigo Labat Marcos, Rodney Capp Pallotta, Francesca Diomede, Oriana Trubiani, Natalia De Isla, Lucio Frigo
BACKGROUND: The temporomandibular joint (TMJ) is a structure of the craniofacial complex affected by neurological diseases. Orthopedic and musculoskeletal changes can also cause temporomandibular disorders (TMD) and pain. Low-level laser (LLL) therapy has been studied in the treatment of temporomandibular jaw (TMJ) dysfunction, and controversial results were obtained. OBJECTIVE: The objective of this work was comparing the physiotherapeutic and drug protocol (PDP) to LLL therapy in the treatment of pain associated with TMD...
November 29, 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/27881916/osseointegration-of-nanohydroxyapatite-or-nano-calcium-silicate-incorporated-polyetheretherketone-bioactive-composites-in-vivo
#2
Rui Ma, Zhifeng Yu, Songchao Tang, Yongkang Pan, Jie Wei, Tingting Tang
Polyetheretherketone (PEEK) exhibits appropriate biomechanical strength as well as good biocompatibility and stable chemical properties but lacks bioactivity and cannot achieve highly efficient osseointegration after implantation. Incorporating bioceramics into the PEEK matrix is a feasible approach for improving its bioactivity. In this study, nanohydroxyapatite (n-HA) and nano-calcium silicate (n-CS) were separately incorporated into PEEK to prepare n-HA/PEEK and n-CS/PEEK biocomposites, respectively, using a compounding and injection-molding technique, and the in vitro degradation characteristics were evaluated...
2016: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/27836765/nasal-breathing-and-the-vertical-dimension-a-cephalometric-study
#3
Amal El Aouame, Asmaa Daoui, Farid El Quars
INTRODUCTION: The aim of this work was to perform a cephalometric analysis of the craniofacial parameters and natural head posture of mouth-breathers compared with control subjects, and to study the relationship between nose-breathing and the vertical dimension. MATERIAL AND METHODS: The headfilms taken at start of treatment of 53 cases (28 girls, 25 boys) aged 9 to 30 who consulted the dento-facial orthopedic department of the Ibn Rochd Casablanca dental consultation and treatment center were studied...
November 8, 2016: International Orthodontics
https://www.readbyqxmd.com/read/27811389/hydrogel-fibers-encapsulating-human-stem-cells-in-an-injectable-calcium-phosphate-scaffold-for-bone-tissue-engineering
#4
Lin Wang, Ping Wang, Michael D Weir, Mark A Reynolds, Liang Zhao, Hockin H K Xu
Human induced pluripotent stem cells (hiPSCs), human embryonic stem cells (hESCs) and human umbilical cord mesenchymal stem cells (hUCMSCs) are exciting cell sources for use in regenerative medicine. There have been no reports on long hydrogel fibers encapsulating stem cells inside an injectable calcium phosphate cement (CPC) scaffold for bone tissue engineering. The objectives of this study were: (1) to develop a novel injectable CPC construct containing hydrogel fibers encapsulating cells for bone engineering, and (2) to investigate and compare cell viability, proliferation and osteogenic differentiation of hiPSC-MSCs, hESC-MSCs and hUCMSCs in injectable CPC...
November 4, 2016: Biomedical Materials
https://www.readbyqxmd.com/read/27726836/-normal-and-pathologic-mandible-development-practical-deductions-in-maxillo-dento-facial-orthopedics
#5
Jean-Michel Salagnac
INTRODUCTION: The mandible consists of different segments, each of which possess its own specific characteristics regarding emergence, ossification during growth and pathologies. Orthodontists need to be very familiar with these developmental anomalies if they are to avoid failure in their orthopedic or orthodontic treatments and in order to understand the reasons for the lack of success of "conventional" treatments. Each segment must develop correctly if the mandible is to achieve optimal development and occupy a normal position within the cranio-facial complex...
September 2016: L' Orthodontie Française
https://www.readbyqxmd.com/read/27619046/three-dimensional-printing-a-review-on-the-utility-within-medicine-and-otolaryngology
#6
REVIEW
Rachel Kaye, Todd Goldstein, David Zeltsman, Daniel A Grande, Lee P Smith
Three dimensional (3D) printing is a novel technique that has evolved over the past 35 years and has the potential to revolutionize the field of medicine with its inherent advantages of customizability and the ability to create complex shapes with precision. It has been used extensively within the fields of orthopedics, dentistry, and craniofacial reconstruction with wide ranging utility including, medical modeling, surgical planning and the production of custom plates, screws and surgical guides. Furthermore, it has been used for similar means in the field of Otorhinolaryngology and also has potential to revolutionize the treatment of airway malacia...
October 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27612810/injectable-calcium-phosphate-with-hydrogel-fibers-encapsulating-induced-pluripotent-dental-pulp-and-bone-marrow-stem-cells-for-bone-repair
#7
Lin Wang, Chi Zhang, Chunyan Li, Michael D Weir, Ping Wang, Mark A Reynolds, Liang Zhao, Hockin H K Xu
Human induced pluripotent stem cell-derived mesenchymal stem cells (hiPSC-MSCs), dental pulp stem cells (hDPSCs) and bone marrow MSCs (hBMSCs) are exciting cell sources in regenerative medicine. However, there has been no report comparing hDPSCs, hBMSCs and hiPSC-MSCs for bone engineering in an injectable calcium phosphate cement (CPC) scaffold. The objectives of this study were to: (1) develop a novel injectable CPC containing hydrogel fibers encapsulating stem cells for bone engineering, and (2) compare cell viability, proliferation and osteogenic differentiation of hDPSCs, hiPSC-MSCs from bone marrow (BM-hiPSC-MSCs) and from foreskin (FS-hiPSC-MSCs), and hBMSCs in CPC for the first time...
December 1, 2016: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27505993/headache-and-jaw-locking-comorbidity-with-daytime-sleepiness
#8
Steven R Olmos, Franklin Garcia-Godoy, Timothy L Hottel, Nhu Quynh T Tran
PURPOSE: To investigate the relationship between craniofacial pain symptoms (painful conditions present in the cranium and face, including jaw joint-related pathology and primary headache conditions) and daytime sleepiness, determined by the Epworth sleepiness scale (ESS), to correlate comorbidity as well as potential predictive factors. METHODS: 1,171 patients seeking care for chronic pain and/or sleep-related breathing disorders (SRBDs) at 11 international treatment centers were included in the study...
June 2016: American Journal of Dentistry
https://www.readbyqxmd.com/read/27472573/orthodontic-consideration-in-patients-with-beta-thalassemia-major-case-report-and-literature-review
#9
Shmuel Einy, Hagai Hazan-Molina, Ayelet Ben-Barak, Dror Aizenbud
OBJECTIVE: Beta Thalassemia (βT) patients present a unique facial appearance and specific craniofacial, jaw and dental patterns. Although this anomaly often requires orthodontic management, βT patients have received scant attention in the orthodontic and dental literature over the past 50 years. The aim of this article is to review the characteristic craniofacial and dental manifestation pattern of βT patients and to emphasize their preferred orthodontic management protocol by presenting a βT orthodontic treated patient...
2016: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/27403068/a-modified-presurgical-orthopedic-nasoalveolar-molding-device-in-the-treatment-of-unilateral-cleft-lip-and-palate
#10
Chitravelu Siva Subramanian, N K K Koteswara Prasad, Arun B Chitharanjan, Eric Jein Wein Liou
Nasoalveolar molding (NAM) can be done effectively to reshape the nasal cartilage and mold the maxillary dentoalveolar arch before surgical cleft lip repair and primary rhinoplasty. Presurgical NAM helps as an adjunct procedure to enhance the esthetic and functional outcome of the surgical procedures. We have developed a modified NAM device to suit to the needs of the patients coming from distant places for the treatment. This device helps in reducing the number of frequent visits the patient needs to take to the craniofacial center...
July 2016: European Journal of Dentistry
https://www.readbyqxmd.com/read/27348947/goldenhar-syndrome-and-pain-related-temporomandibular-disorders-a-case-report
#11
Shehryar Nasir Khawaja, Heidi Crow, Yoly Gonzalez
Goldenhar syndrome (GS) is a development syndrome, characterized by incomplete development of the craniofacial region. The involvement is mainly unilateral; it varies from being mild to severe; and it can range from malocclusion and facial asymmetry to a more complex phenotype with complete absence of the mandibular ramus and temporomandibular joint. However, orthopedic symptoms of orofacial pain and dysfunction have not generally been considered as part of the symptom complex in GS cases. The case presented here is of a 15-year-old Caucasian patient, who was referred for evaluation because of bilateral pain in the masticatory muscles and temporomandibular joints...
April 2016: New York State Dental Journal
https://www.readbyqxmd.com/read/27346752/-scar-revision-in-children-clinical-situations-and-solutions
#12
V Duquennoy-Martinot, A Belkhou, L Pasquesoone, C Depoortère, P Guerreschi
The scar of soft tissues is a permanent stigma of a trauma but it can sometimes be improved. It is more or less accepted by the patient and may be the source of a significant physical and psychosocial impact that leads to a request for a scar revision. Even if the child presents generally an excellent ability to heal, the quality of the scar depends on many factors such as the age, the type of scar or trauma and the affected body area. Thus, its aesthetic impact, functional but also on the growth of the child will be different...
June 23, 2016: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/27313006/runx2-modified-dental-pulp-stem-cells-dpscs-enhance-new-bone-formation-during-rapid-distraction-osteogenesis-do
#13
Guijuan Feng, Jinlong Zhang, Xingmei Feng, Senbin Wu, Dan Huang, Jing Hu, Songsong Zhu, Donghui Song
Distraction osteogenesis (DO) remains a major challenge in orthopedic and craniofacial surgery. The transplantion of mesenchymal stem cells (MSCs) could reduce the treatment period and the associated complications by increasing new bone formation during long-bone DO. Runt-related transcription factor 2 (Runx2) encodes a nuclear protein that is a pivotal regulator of osteoblast differentiation. It significantly stimulates calcium accumulation and alkaline phosphatase (ALP) activity in dental pulp stem cells (DPSCs)...
June 13, 2016: Differentiation; Research in Biological Diversity
https://www.readbyqxmd.com/read/27310816/anterior-lateral-thigh-osteomyocutaneous-free-flap-reconstruction-in-the-head-and-neck-the-anterolateral-thigh-osteomyocutaneous-femur-bone-flap
#14
Robert M Brody, Nirnimesh C Pandey, Andrés M Bur, Bert W O'Malley, Christopher H Rassekh, Gregory S Weinstein, Ara A Chalian, Jason G Newman, Steven B Cannady
BACKGROUND: The anterolateral thigh (ALT) free flap is one of the most commonly used donor sites in head and neck reconstruction, however, it is not typically considered when an osseous component is needed. METHODS: Soft tissue harvests, cadaveric study, and retrospective analysis of a series of 10 patients undergoing angiography were performed to assess vascular supply to the femoral cortex. In 6 patients, corticocancellous split-femur was incorporated into the ALT to reconstruct bony defects of the head and neck...
December 2016: Head & Neck
https://www.readbyqxmd.com/read/27303117/improved-surgery-planning-using-3-d-printing-a-case-study
#15
A J Singhal, V Shetty, K R Bhagavan, Ananthan Ragothaman, V Shetty, Ganesh Koneru, M Agarwala
The role of 3-D printing is presented for improved patient-specific surgery planning. Key benefits are time saved and surgery outcome. Two hard-tissue surgery models were 3-D printed, for orthopedic, pelvic surgery, and craniofacial surgery. We discuss software data conversion in computed tomography (CT)/magnetic resonance (MR) medical image for 3-D printing. 3-D printed models save time in surgery planning and help visualize complex pre-operative anatomy. Time saved in surgery planning can be as much as two thirds...
April 2016: Indian Journal of Surgery
https://www.readbyqxmd.com/read/27280476/two-dimensional-magnesium-phosphate-nanosheets-form-highly-thixotropic-gels-that-up-regulate-bone-formation
#16
Marco Laurenti, Ahmed Al Subaie, Mohamed-Nur Abdallah, Arthur R G Cortes, Jerome L Ackerman, Hojatollah Vali, Kaustuv Basu, Yu Ling Zhang, Monzur Murshed, Satu Strandman, Julian Zhu, Nicholas Makhoul, Jake E Barralet, Faleh Tamimi
Hydrogels composed of two-dimensional (2D) nanomaterials have become an important alternative to replace traditional inorganic scaffolds for tissue engineering. Here, we describe a novel nanocrystalline material with 2D morphology that was synthesized by tuning the crystallization of the sodium-magnesium-phosphate system. We discovered that the sodium ion can regulate the precipitation of magnesium phosphate by interacting with the crystal's surface causing a preferential crystal growth that results in 2D morphology...
August 10, 2016: Nano Letters
https://www.readbyqxmd.com/read/27134455/a-unique-functional-craniofacial-suture-that-may-normally-never-ossify-a-cone-beam-computed-tomography-based-report-of-two-cases
#17
Karim Poorsattar Bejeh Mir, Arash Poorsattar Bejeh Mir, Morvarid Poorsattar Bejeh Mir, Sina Haghanifar
The premise of complete ossification of midpalatal suture in early adulthood still has its popularity, though conflicting data are emerging in the literature. A 49-year-old male and a 54-year-old female Iranian patient, both dentulous, were referred to a Maxillofacial Radiology Center to be evaluated for implant insertion. In cone-beam computed tomography (CBCT) evaluation, an in-ossified suture was found in anterior two-third of midpalatal region of both individuals. The application of clinical vignettes from CBCT findings for maxillofacial orthodontic and orthopedic purposes is of value...
January 2016: Indian Journal of Dentistry
https://www.readbyqxmd.com/read/27104930/evaluation-of-multi-scale-mineralized-collagen-polycaprolactone-composites-for-bone-tissue-engineering
#18
D W Weisgerber, K Erning, C L Flanagan, S J Hollister, B A C Harley
A particular challenge in biomaterial development for treating orthopedic injuries stems from the need to balance bioactive design criteria with the mechanical and geometric constraints governed by the physiological wound environment. Such trade-offs are of particular importance in large craniofacial bone defects which arise from both acute trauma and chronic conditions. Ongoing efforts in our laboratory have demonstrated a mineralized collagen biomaterial that can promote human mesenchymal stem cell osteogenesis in the absence of osteogenic media but that possesses suboptimal mechanical properties in regards to use in loaded wound sites...
August 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/26608140/demineralized-bone-and-bmps-basic-science-and-clinical-utility
#19
REVIEW
Julie Glowacki
The clinical demand for bone void fillers led to the development of off-the-shelf banked bone and synthetic and biologic substitute materials to be used either alone or as bone graft volume extenders. Demineralized bone (DB) has a remarkable capacity to induce new bone formation even when implanted subcutaneously in experimental animals, a phenomenon termed "osteoinduction." DB products are now widely available through tissue bank procurement of bone from rigorously screened donors. When properly processed, DB products are useful in craniomaxillofacial, oral, hand, and orthopedic applications...
December 2015: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/26511180/reconstruction-of-the-zygomatic-bone-with-smartbone%C3%A2-case-report
#20
F Grecchi, G Perale, V Candotto, A Busato, M Pascali, F Carinci
The repair of complex craniofacial bone defects is challenging and a successful result depends on the defect size, the quality of the soft tissue covering the defect and the choice of reconstructive method. Autologous bone grafts are the gold standard for bone replacement. Tissue engineered constructs are temporary substitutes developed to treat damaged or lost tissue. Recent advances in materials science have provided an abundance of innovations, underlining the increasing importance of polymer in this field...
July 2015: Journal of Biological Regulators and Homeostatic Agents
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