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https://www.readbyqxmd.com/read/28478963/shoulder-and-elbow-pain-in-elementary-school-baseball-players-the%C3%A2-results-from-a-nation-wide-survey-in-japan
#1
Kenji Takagishi, Tetsuya Matsuura, Takashi Masatomi, Etsuo Chosa, Tsuyoshi Tajika, Mikihiko Watanabe, Tetsu Iwama, Toshiro Otani, Katsunori Inagaki, Hiroyasu Ikegami, Mitsuhiro Aoki, Ko Kato, Toru Okuwaki, Koichi Sairyo, Yasushi Kameyama, Akira Maeda, Moroe Beppu
BACKGROUND: Despite recommendations on how to prevent baseball injuries in youths by the Japanese Society of Clinical Sports Medicine, shoulder and elbow pain still frequently occurs in young baseball players. We conducted a questionnaire survey among baseball players at elementary schools across the country to understand the practice conditions of players, examining the risk factors of shoulder and elbow pain in baseball players. METHODS: The questionnaire survey was conducted among elementary school baseball players as members of the Baseball Federation of Japan in September 2015...
May 3, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28446504/feasibility-of-ultra-high-throughput-functional-screening-of-melanoma-biopsies-for-discovery-of-novel-cancer-drug-combinations
#2
Adam A Friedman, Yun Xia, Lorenzo Trippa, Long P Le, Vivien Igras, Dennie T Frederick, Jennifer A Wargo, Kenneth K Tanabe, Donald P Lawrence, Donna S Neuberg, Keith T Flaherty, David Fisher
Purpose: Successful development of targeted therapy combinations for cancer patients depends on first discovering such combinations in predictive preclinical models. Stable cell lines and mouse xenograft models can have genetic and phenotypic drift and may take too long to generate to be useful as a personalized medicine tool. <p>Experimental Design: To overcome these limitations, we have used a platform of ultra-high-throughput functional screening of primary biopsies preserving both cancer and stroma cell populations from melanoma patients to nominate such novel combinations from a library of  thousands of drug combinations in a patient-specific manner within days of biopsy...
April 26, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28445217/why-health-insurance-matters-and-why-research-evidence-should-too
#3
Benjamin D Sommers
In the current debate over the future of the Affordable Care Act (ACA), research evidence on the impact of the law and the effects of health insurance coverage in general is critical. Studies of health insurance expansion over the past decade have demonstrated that coverage expansions can produce significant reductions in mortality-particularly among minorities, those living in poorer areas, and those with chronic conditions potentially treatable with timely medical care. More recent studies of the ACA in particular demonstrate that the law has produced historically large reductions in the uninsured rate, with resulting improvements in access to care, perceived quality of care, and self-reported health...
April 25, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28408135/the-missing-person-the-outcome-of-the-rule-based-totalitarianism-of-too-much-contemporary-healthcare
#4
Iona Heath
OBJECTIVES: Medicine has an obsession with scientific progress and a misplaced belief in the perfectibility of the human body and mind and, as a result, there seems never to be time for the necessary backward glance. If we in healthcare are to learn any of the lessons of history, it seems important that we pay attention to those who have suffered at the sharp end of historical events. METHODS AND RESULTS: This paper invokes thinkers and writers who lived lives scarred by totalitarian politics...
April 3, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28392856/impact-of-physical-activity-in-cardiovascular-and-musculoskeletal-health-can-motion-be-medicine
#5
REVIEW
Gannon L Curtis, Morad Chughtai, Anton Khlopas, Jared M Newman, Rafay Khan, Shervin Shaffiy, Ali Nadhim, Anil Bhave, Michael A Mont
Physical activity is a well-known therapeutic tool for various types of medical conditions, including vasculopathic diseases such as coronary artery disease, stroke, type 2 diabetes, and obesity. Additionally, increased physical activity has been proposed as a therapy to improve musculoskeletal health; however, there are conflicting reports about physical activity potentially leading to degenerative musculoskeletal disease, especially osteoarthritis (OA). Additionally, although physical activity is known to have its benefits, it is unclear as to what amount of physical activity is the most advantageous...
May 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28341581/the-graham-jackson-memorial-lecture-issm-2016-the-man-who-knew-too-much-time-to-recognize-erectile-dysfunction-and-low-testosterone-as-independent-risk-factors-for-cardiovascular-disease
#6
REVIEW
Geoffrey Hackett
INTRODUCTION: Graham Jackson introduced the concept that erectile dysfunction (ED) is a marker for undiagnosed cardiovascular (CV) disease and future events. In the Princeton 3 guidelines, he recognized the important impact of testosterone deficiency (TD) on all-cause and CV mortality. Recent evidence suggests that testosterone therapy to target levels and for sufficient duration decreases CV events. Unfortunately, this had a modest impact on CV disease management because ED is not incorporated into current risk calculators...
March 21, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28294098/come-on-using-intervention-mapping-to-help-healthy-pregnant-women-achieve-healthy-weight-gain
#7
Astrid Merkx, Marlein Ausems, Raymond de Vries, Marianne J Nieuwenhuijze
OBJECTIVE: Gaining too much or too little weight in pregnancy (according to Institute of Medicine (IOM) guidelines) negatively affects both mother and child, but many women find it difficult to manage their gestational weight gain (GWG). Here we describe the use of the intervention mapping protocol to design 'Come On!', an intervention to promote adequate GWG among healthy pregnant women. DESIGN: We used the six steps of intervention mapping: (i) needs assessment; (ii) formulation of change objectives; (iii) selection of theory-based methods and practical strategies; (iv) development of the intervention programme; (v) development of an adoption and implementation plan; and (vi) development of an evaluation plan...
March 15, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28289853/information-mismatch-cancer-risk-counseling-with-diverse-underserved-patients
#8
Galen Joseph, Rena J Pasick, Dean Schillinger, Judith Luce, Claudia Guerra, Janice Ka Yan Cheng
As genetics and genomics become part of mainstream Medicine, these advances have the potential to reduce or exacerbate health disparities. Gaps in effective communication (where all parties share the same meaning) are widely recognized as a major contributor to health disparities. The purpose of this study was to examine GC-patient communication in real time, to assess its effectiveness from the patient perspective, and then to pilot intervention strategies to improve the communication. We observed 64 English-, 35 Spanish- and 25 Chinese-speaking (n = 124) public hospital patients and 10 GCs in 170 GC appointments, and interviewed 49 patients who were offered testing using the audio recordings to stimulate recall and probe specific aspects of the communication...
March 13, 2017: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/28152848/do-perceived-barriers-to-lung-cancer-screening-differ-between-attending-physicians-and-residents
#9
Laura Jones, Katie Marsh, M Patricia Rivera, Paul Molina, Dan Reuland, J Michael Bowling, Katherine Birchard, Susan Maygarden, Louise Henderson
192 Background: In February 2015, legislation went into effect requiring Medicare to cover lung cancer (LC) screening with low dose computed tomography (LDCT) for high risk patients. Despite this, much debate and uncertainty exist among physicians about LC screening best practices. We aim to compare perceived barriers to LC screening between resident and attending physicians in Family and Internal Medicine, two departments selected for their high likelihood of seeing patients eligible for LC screening. METHODS: Between February and July of 2015, a 23 question Qualtrics survey was conducted among physicians and residents at a large academic hospital to assess knowledge and beliefs of LC screening...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28131024/-too-much-medicine-insights-and-explanations-from-economic-theory-and-research
#10
Martin Hensher, John Tisdell, Craig Zimitat
Increasing attention has been paid in recent years to the problem of "too much medicine", whereby patients receive unnecessary investigations and treatments providing them with little or no benefit, but which expose them to risks of harm. Despite this phenomenon potentially constituting an inefficient use of health care resources, it has received limited direct attention from health economists. This paper considers "too much medicine" as a form of overconsumption, drawing on research from health economics, behavioural economics and ecological economics to identify possible explanations for and drivers of overconsumption...
January 18, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28067744/resident-education-in-female-pelvic-medicine-and-reconstructive-surgery
#11
Katie Propst, Adam C Steinberg, David M O'Sullivan, Megan O Schimpf, Christine LaSala
OBJECTIVE: The aim of this study was to evaluate whether obstetrics and gynecology trainees feel satisfied with the female pelvic medicine and reconstructive surgery (FPMRS) education received in residency. METHODS: This is a survey study of obstetrics and gynecology residents in the United States and Puerto Rico during the 2015-2016 academic year. The anonymous 29-question survey was approved by the Hartford HealthCare institutional review board. Responses were included only if the trainee had ever rotated on the FPMRS service...
January 6, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28034950/statins-for-primary-prevention-in-people-with-a-10-10-year-cardiovascular-risk-too-much-medicine-too-soon
#12
Dharani Yerrakalva, Simon J Griffin
No abstract text is available yet for this article.
January 2017: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/28002724/too-much-of-a-good-thing-chronic-ifn-fuels-resistance-to-cancer-immunotherapy
#13
James L Reading, Sergio A Quezada
Immune checkpoint blockade (ICB) is revolutionizing cancer medicine, yet the molecular basis of resistance remains unclear. In a recent issue of Cell, Benci et al. (2016) demonstrate that sustained interferon signaling is central to the development of PD-L1-dependent and -independent resistance to ICB.
December 20, 2016: Immunity
https://www.readbyqxmd.com/read/27881558/the-american-heart-association-s-new-institute-for-precision-cardiovascular-medicine
#14
Steven R Houser
No abstract text is available yet for this article.
December 13, 2016: Circulation
https://www.readbyqxmd.com/read/27870086/health-care-for-nfl-players-upholding-physician-standards-and-enhancing-the-doctor-patient-relationship
#15
Laurent Duvernay-Tardif
Beginning my third year with the Kansas City Chiefs and being also a medical student at McGill University, I was at first a little reluctant to comment on Glenn Cohen et al.'s critique of the National Football League's structure involving player health and team doctors, but the opportunity to provide a perspective as both a football player and a medical student was too much to forgo. Because of my athletic and academic background, I am often asked what I think about injuries in professional sports and about the role of sports medicine physicians, and Cohen et al...
November 2016: Hastings Center Report
https://www.readbyqxmd.com/read/27812335/rapid-hplc-quantification-approach-for-detection-of-active-constituents-in-modern-combinatorial-formula-san-huang-xie-xin-tang-shxxt
#16
Tung-Ying Wu, Fang-Rong Chang, Jing-Ru Liou, I-Wen Lo, Tang-Chia Chung, Li-Yao Lee, Chun-Chen Chi, Ying-Chi Du, Man-Hon Wong, Suh-Hang Hank Juo, Chun-Chen Lee, Yang-Chang Wu
San-Huang-Xie-Xin-Tang (SHXXT), one of the most important traditional Chinese medicinal formulas, is comprised by three herbal medicines, the rhizome of Rheum officinale [or Rheum tanguticum (Polygonaceae) (Dahuang in Chinese)], the root of Scutellaria baicalensis (Labiatae) (Huangqin in Chinese), and the rhizome of Coptis chinensis (Ranunculaceae) (Huanglian in Chinese) in the ratios of 2:1:1 or 1:1:1. This study is aimed to quantitate and qualify of SHXXT, by a rapid, convenient, and effective HPLC-PDA approach associated with LC-MS technique...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27806472/analytical-assessment-of-belief-about-medicine-among-patients-with-hypertension-a-case-study-on-patients-referred-to-medical-centers
#17
Mohammad Edris Arbabshastan, Azizollah Arbabisarjou, Iraj Zareban, Mahlagha Dehghan, Saeed Pakdel, Sedigheh Iranmanesh
INTRODUCTION & OBJECTIVE: Hypertension (HTN) is one of the major health problems in many countries. Medicinal treatments and lifestyle modification have so far failed to effectively influence blood pressure control. Hence, this study intended to analytically assess the belief about medicine among hypertensive patients who referred to medical centers during 2015. MATERIALS & METHODS: This was a descriptive-analytical, cross-sectional study. The population consisted of all patients who referred to health centers and doctors' offices for internal medicine and heart diseases...
June 30, 2016: Global Journal of Health Science
https://www.readbyqxmd.com/read/27753827/sy-02-3-resolving-ethical-problems-in-hypertension-treatment-trials
#18
Iwao Kuwajima
Since a concept of Evidence-based Medicine appeared in medical field in 1991, modern medical treatment have been remarkably changed.However, delusive belief of EBM without criticism has brought negative aspect, such as utilization of EBM by companies as a tool of promotion of drug or medical device.Although most of clinical trials were financially supported by drug companies. result of clinical trial does not always ended in favor of test drug or device. When negative results appeared, various way were taken by industry such as usage of SPIN, emphasizing secondary endpoint...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27646674/too-much-or-never-enough-a-response-to-treatment-of-opioid-disorders-in-canada-looking-at-the-other-epidemic
#19
EDITORIAL
Joseph K Eibl, Kristen A Morin-Taus, David C Marsh
Prescription opioid (PO) misuse is a major health concern across North America, and it is the primary cause of preventable death for the 18-35 year old demographic. Medication assisted therapy including methadone and buprenorphine, is the standard of care for patients with opioid-dependence. Moreover, both of these medications are recognized as essential medicines by World Health Organization. In Ontario Canada, the availability of medication assisted therapy has expanded substantially, with almost a ten-fold increase number of patients accessing methadone in Ontario in the past decade...
September 20, 2016: Substance Abuse Treatment, Prevention, and Policy
https://www.readbyqxmd.com/read/27642880/sy-02-3-resolving-ethical-problems-in-hypertension-treatment-trials
#20
Iwao Kuwajima
Since a concept of Evidence-based Medicine appeared in medical field in 1991, modern medical treatment have been remarkably changed.However, delusive belief of EBM without criticism has brought negative aspect, such as utilization of EBM by companies as a tool of promotion of drug or medical device.Although most of clinical trials were financially supported by drug companies. result of clinical trial does not always ended in favor of test drug or device. When negative results appeared, various way were taken by industry such as usage of SPIN, emphasizing secondary endpoint...
September 2016: Journal of Hypertension
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