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https://www.readbyqxmd.com/read/29172881/the-institute-of-medicine-recommendation-for-gestational-weight-gain-is-probably-not-optimal-among-non-american-pregnant-women-a-retrospective-study-from-china
#1
Xiang Jiang, Ming Liu, Yuehua Song, Jing Mao, Mulan Zhou, Zhenfang Ma, Xiaohu Qian, Zhimin Han, Tao Duan
PURPOSE: To investigate whether the Institute of Medicine (IOM) recommended gestational weight gain (GWG) range is optimal among Chinese singleton pregnant women. METHODS: For the purpose of a retrospective observational study, data on 8209 mature singleton deliveries in Shanghai from January 2014 to December 2016 were extracted from medical records in terms of clinical performance. All cases were categorized as undergainers, appropriate-gainers, and above-gainers according to IOM recommended gestational weight gain range after stratification of maternal BMI and proportions of three categories were calculated...
November 27, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29132221/2009-iom-guidelines-for-gestational-weight-gain-how-well-do-they-predict-outcomes-across-ethnic-groups
#2
Amal R Khanolkar, Gillian E Hanley, Ilona Koupil, Patricia A Janssen
OBJECTIVE: To determine whether the Institute Of Medicine's (IOM) 2009 guidelines for weight-gain during pregnancy are predictive of maternal and infant outcomes in ethnic minority populations. METHODS: We designed a population-based study using administrative data on 181,948 women who delivered live singleton births in Washington State between 2006-2008. We examined risks of gestational hypertension, preeclampsia/eclampsia, cesarean delivery, and extended hospital stay in White, Black, Native-American, East-Asian, Hispanic, South-Asian and Hawaiian/Pacific islander women according to whether they gained more or less weight during pregnancy than recommended by IOM guidelines...
November 13, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/29095554/patients-perceptions-of-their-doctors-notes-and-after-visit-summaries-a-mixed-methods-study-of-patients-at-safety-net-clinics
#3
Brittaney M Belyeu, Jared W Klein, Lisa M Reisch, Sue Peacock, Natalia V Oster, Joann G Elmore, Sara L Jackson
BACKGROUND: Patients are increasingly offered electronic access to their doctors' notes, and many consistently receive paper After-Visit Summaries. Specific feedback from patients about notes and summaries are lacking, particularly within safety-net settings. DESIGN: A mixed methods study SETTING AND PARTICIPANTS: Patients with poorly controlled diabetes attending two urban safety-net primary care clinics in Washington State. METHODS: Patients read their own most recent clinic note and After-Visit Summary, then completed a brief survey followed by a focus group discussion (3 groups in a large general medicine teaching clinic and 1 in an HIV/AIDS clinic) about their perceptions of the clinic note and After-Visit Summary...
November 2, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/29082808/an-overview-of-the-current-management-of-chronic-obstructive-pulmonary-disease-can-we-go-beyond-the-gold-recommendations
#4
Mario Cazzola, Paola Rogliani, Ermanno Puxeddu, Josuel Ora, Maria Gabriella Matera
Treatment recommendations are based on randomized controlled trials (RCTs). However, only about 1 in 20 people meet the inclusion criteria for RCTs forming consensus guidelines in chronic obstructive pulmonary disease (COPD). Consequently, the one-size-fits-all approach focused merely on traditional symptoms and risk of exacerbations is inadequate to treat COPD. COPD needs a personalized medicine strategy because of the relevance of COPD heterogeneity for subject-based health risk assessment and stratification in the clinical arena...
November 3, 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/29082176/clinical-use-of-sperm-dna-fragmentation-analysis-results-a-practical-example-of-how-to-deal-with-too-much-information-from-the-literature-in-reproductive-medicine
#5
COMMENT
Nicolás Garrido, Rocío Rivera, Satur Luján
No abstract text is available yet for this article.
September 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29075819/augmentation-mastopexy-with-a-dermal-encapsulated-round-or-anatomic-autoprosthesis
#6
Safvet Ors
INTRODUCTION: Several factors, such as aging, pregnancy, and weight loss, reduce the elasticity of the breast tissue, and ptosis occurs. Due to aging and gravity, it is not possible to completely prevent breast ptosis. The goal is to delay the recurrence of ptosis as much as possible. PATIENTS AND METHODS: This study included 20 female patients aged 25-55 years. The patients who underwent surgery had different levels of ptosis. Although the patients wanted their breasts to be lifted and an increase in projection, they did not want implants to be used...
October 26, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29062539/patient-organization-involvement-and-the-challenge-of-securing-access-to-treatments-for-rare-diseases-report-of-a-policy-engagement-workshop
#7
Koichi Mikami, Steve Sturdy
PLAIN ENGLISH SUMMARY: Patients with rare diseases often help to develop new treatments for their conditions. But once developed, those treatments are sometimes priced too high for many patients to access them. We became aware that this is a problem in the course of a social science research project that examines the place of rare diseases in health policy. We therefore organized a two-day workshop to try and understand why this problem occurs and what might be done about it. The people who participated in our workshop were: representatives of rare disease patient organizations, experts in matters of drug regulation and assessment of new health technologies, consultants involved with companies producing treatments for rare diseases, and social scientists researching related issues...
2017: Research Involvement and Engagement
https://www.readbyqxmd.com/read/28929199/sophorolipid-production-by-yeasts-a-critical-review-of-the-literature-and-suggestions-for-future-research
#8
REVIEW
Silke Claus, Inge N A Van Bogaert
Sophorolipids are well-known biosurfactants produced by yeasts, having potential applications ranging from nanomaterials, medicine, and cosmetics to large-volume applications such as cleaning and soil remediation. Because of their environmentally friendly nature, they attained much interest during the past decades as a sustainable and ecological alternative to petroleum-derived surfactants. Stronger yet, research activities and scientific publications on the topic are ever increasing. However, often these studies lack proper producer strain identification and detailed structural product characterization...
November 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28903757/access-to-medicines-and-hepatitis-c-in-africa-can-tiered-pricing-and-voluntary-licencing-assure-universal-access-health-equity-and-fairness
#9
Yibeltal Assefa, Peter S Hill, Anar Ulikpan, Owain D Williams
BACKGROUND: The recent introduction of Direct Acting Antivirals (DAAs) for treating Hepatitis C Virus (HCV) can significantly assist in the world reaching the international target of elimination by 2030. Yet, the challenge facing many individuals and countries today lies with their ability to access these treatments due to their relatively high prices. Gilead Sciences applies differential pricing and licensing strategies arguing that this provides fairer and more equitable access to these life-saving medicines...
September 13, 2017: Globalization and Health
https://www.readbyqxmd.com/read/28745208/thiazole-containing-heterocycles-with-cns-activity
#10
Priyanka Kalal, Divyani Gandhi, Prakash Prajapat, Shikha Agarwal
BACKGROUND: Thiazoles are promising scaffolds in the area of medicinal and pharmaceutical chemistry and have accounted to show different pharmacophoric properties. For the last years, thiazole derivatives have focused too much attention to develop different new CNS active agents. It has been broadly used to generate diverse therapeutic agents against various CNS targets. Histamine H3 receptors are seriously involved in the pathophysiology of numerous disorders of the central nervous system...
July 24, 2017: Current Drug Discovery Technologies
https://www.readbyqxmd.com/read/28666440/do-medical-students-and-young-physicians-assess-reliably-their-self-efficacy-regarding-communication-skills-a-prospective-study-from-end-of-medical-school-until-end-of-internship
#11
Tore Gude, Arnstein Finset, Tor Anvik, Anders Bærheim, Ole Bernt Fasmer, Hilde Grimstad, Per Vaglum
BACKGROUND: This prospective study from end of medical school through internship investigates the course and possible change of self- reported self-efficacy in communication skills compared with observers' ratings of such skills in consultations with simulated patients. METHODS: Sixty-two medical students (43 females) from four Norwegian universities performed a videotaped consultation with a simulated patient immediately before medical school graduation (T1) and after internship (internal medicine, surgery and family medicine, half a year each - T2)...
June 30, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28664306/axillary-advancement-suture-to-minimize-post-implantation-deformity-in-implant-based-breast-reconstruction
#12
Jun Ho Lee, Chi-Ho Yeo, Kyu-Jin Chung, Taegon Kim
Patients who have undergone implant-based breast reconstruction after skin-sparing mastectomy often complain about bulging on the upper flank or inferior axillary area. This is most likely because the subcutaneous tissue layer of the upper flank, which is continuous with the breast tissue, tends to show inferolateral drooping once the subcutaneous tissue becomes loose after eliminating the breast parenchyma. In addition, one of the weaknesses of implant surgery is that implants cannot completely replace the tissue removed during skin-sparing mastectomy (SSM)...
October 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28478963/shoulder-and-elbow-pain-in-elementary-school-baseball-players-the%C3%A2-results-from-a-nation-wide-survey-in-japan
#13
Kenji Takagishi, Tetsuya Matsuura, Takashi Masatomi, Etsuo Chosa, Tsuyoshi Tajika, Mikihiko Watanabe, Tetsu Iwama, Toshiro Otani, Katsunori Inagaki, Hiroyasu Ikegami, Mitsuhiro Aoki, Ko Kato, Toru Okuwaki, Koichi Sairyo, Yasushi Kameyama, Akira Maeda, Moroe Beppu
BACKGROUND: Despite recommendations on how to prevent baseball injuries in youths by the Japanese Society of Clinical Sports Medicine, shoulder and elbow pain still frequently occurs in young baseball players. We conducted a questionnaire survey among baseball players at elementary schools across the country to understand the practice conditions of players, examining the risk factors of shoulder and elbow pain in baseball players. METHODS: The questionnaire survey was conducted among elementary school baseball players as members of the Baseball Federation of Japan in September 2015...
May 3, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28446504/feasibility-of-ultra-high-throughput-functional-screening-of-melanoma-biopsies-for-discovery-of-novel-cancer-drug-combinations
#14
Adam A Friedman, Yun Xia, Lorenzo Trippa, Long Phi Le, Vivien Igras, Dennie T Frederick, Jennifer A Wargo, Kenneth K Tanabe, Donald P Lawrence, Donna S Neuberg, Keith T Flaherty, David E Fisher
Purpose: Successful development of targeted therapy combinations for cancer patients depends on first discovering such combinations in predictive preclinical models. Stable cell lines and mouse xenograft models can have genetic and phenotypic drift and may take too long to generate to be useful as a personalized medicine tool.Experimental Design: To overcome these limitations, we have used a platform of ultra-high-throughput functional screening of primary biopsies preserving both cancer and stroma cell populations from melanoma patients to nominate such novel combinations from a library of thousands of drug combinations in a patient-specific manner within days of biopsy...
August 15, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28445217/why-health-insurance-matters-and-why-research-evidence-should-too
#15
Benjamin D Sommers
In the current debate over the future of the Affordable Care Act (ACA), research evidence on the impact of the law and the effects of health insurance coverage in general is critical. Studies of health insurance expansion over the past decade have demonstrated that coverage expansions can produce significant reductions in mortality-particularly among minorities, those living in poorer areas, and those with chronic conditions potentially treatable with timely medical care. More recent studies of the ACA in particular demonstrate that the law has produced historically large reductions in the uninsured rate, with resulting improvements in access to care, perceived quality of care, and self-reported health...
September 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28408135/the-missing-person-the-outcome-of-the-rule-based-totalitarianism-of-too-much-contemporary-healthcare
#16
Iona Heath
OBJECTIVES: Medicine has an obsession with scientific progress and a misplaced belief in the perfectibility of the human body and mind and, as a result, there seems never to be time for the necessary backward glance. If we in healthcare are to learn any of the lessons of history, it seems important that we pay attention to those who have suffered at the sharp end of historical events. METHODS AND RESULTS: This paper invokes thinkers and writers who lived lives scarred by totalitarian politics...
November 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28392856/impact-of-physical-activity-in-cardiovascular-and-musculoskeletal-health-can-motion-be-medicine
#17
REVIEW
Gannon L Curtis, Morad Chughtai, Anton Khlopas, Jared M Newman, Rafay Khan, Shervin Shaffiy, Ali Nadhim, Anil Bhave, Michael A Mont
Physical activity is a well-known therapeutic tool for various types of medical conditions, including vasculopathic diseases such as coronary artery disease, stroke, type 2 diabetes, and obesity. Additionally, increased physical activity has been proposed as a therapy to improve musculoskeletal health; however, there are conflicting reports about physical activity potentially leading to degenerative musculoskeletal disease, especially osteoarthritis (OA). Additionally, although physical activity is known to have its benefits, it is unclear as to what amount of physical activity is the most advantageous...
May 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28341581/the-graham-jackson-memorial-lecture-issm-2016-the-man-who-knew-too-much-time-to-recognize-erectile-dysfunction-and-low-testosterone-as-independent-risk-factors-for-cardiovascular-disease
#18
REVIEW
Geoffrey Hackett
INTRODUCTION: Graham Jackson introduced the concept that erectile dysfunction (ED) is a marker for undiagnosed cardiovascular (CV) disease and future events. In the Princeton 3 guidelines, he recognized the important impact of testosterone deficiency (TD) on all-cause and CV mortality. Recent evidence suggests that testosterone therapy to target levels and for sufficient duration decreases CV events. Unfortunately, this had a modest impact on CV disease management because ED is not incorporated into current risk calculators...
March 21, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28294098/come-on-using-intervention-mapping-to-help-healthy-pregnant-women-achieve-healthy-weight-gain
#19
Astrid Merkx, Marlein Ausems, Raymond de Vries, Marianne J Nieuwenhuijze
OBJECTIVE: Gaining too much or too little weight in pregnancy (according to Institute of Medicine (IOM) guidelines) negatively affects both mother and child, but many women find it difficult to manage their gestational weight gain (GWG). Here we describe the use of the intervention mapping protocol to design 'Come On!', an intervention to promote adequate GWG among healthy pregnant women. DESIGN: We used the six steps of intervention mapping: (i) needs assessment; (ii) formulation of change objectives; (iii) selection of theory-based methods and practical strategies; (iv) development of the intervention programme; (v) development of an adoption and implementation plan; and (vi) development of an evaluation plan...
March 15, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28289853/information-mismatch-cancer-risk-counseling-with-diverse-underserved-patients
#20
Galen Joseph, Rena J Pasick, Dean Schillinger, Judith Luce, Claudia Guerra, Janice Ka Yan Cheng
As genetics and genomics become part of mainstream Medicine, these advances have the potential to reduce or exacerbate health disparities. Gaps in effective communication (where all parties share the same meaning) are widely recognized as a major contributor to health disparities. The purpose of this study was to examine GC-patient communication in real time, to assess its effectiveness from the patient perspective, and then to pilot intervention strategies to improve the communication. We observed 64 English-, 35 Spanish- and 25 Chinese-speaking (n = 124) public hospital patients and 10 GCs in 170 GC appointments, and interviewed 49 patients who were offered testing using the audio recordings to stimulate recall and probe specific aspects of the communication...
March 13, 2017: Journal of Genetic Counseling
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