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Shear-wave elastography

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https://www.readbyqxmd.com/read/28344811/the-role-of-imaging-in-the-diagnosis-of-primary-prostate-cancer
#1
Hugh Harvey, Nandita M deSouza
Ultrasound and magnetic resonance imaging (MRI) are key imaging modalities in prostate cancer diagnosis. MRI offers a range of intrinsic contrast mechanisms (T2, diffusion-weighted imaging (DWI), MR spectroscopy (MRS)) and extrinsic contrast-generating options based on tumour vascular state following injection of weakly paramagnetic agents such as gadolinium. Together these parameters are referred to as multiparametric (mp)MRI and are used for detecting and guiding biopsy and staging prostate cancer. Although sensitivity of mpMRI is <75% for disease detection, specificity is >90% and a standardised reporting system together with MR-guided targeted biopsy is the optimal diagnostic pathway...
December 2016: Journal of Clinical Urology
https://www.readbyqxmd.com/read/28343660/a-pilot-study-of-ultrasound-elastography-as-a-non-invasive-method-to-monitor-liver-disease-in-children-with-short-bowel-syndrome
#2
Daniel Lodwick, Molly Dienhart, Jennifer N Cooper, Bonita Fung, Joseph Lopez, Sally Smith, Patrick Warren, Jane Balint, Peter C Minneci
BACKGROUND: Our objective was to evaluate the accuracy of acoustic radiation force impulse (ARFI) elastography in determining extent of liver fibrosis in pediatric patients with short bowel syndrome (SBS). METHODS: This prospective cohort study included pediatric patients with SBS who underwent ultrasound with ARFI measurements of shear wave speed (SWS) and liver biopsy within 30days of each other between 12/2014-9/2015. The mean and median SWS were compared to the stage of fibrosis...
March 16, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28342323/computer-aided-tumor-diagnosis-using-shear-wave-breast-elastography
#3
Woo Kyung Moon, Yao-Sian Huang, Yan-Wei Lee, Shao-Chien Chang, Chung-Ming Lo, Min-Chun Yang, Min Sun Bae, Su Hyun Lee, Jung Min Chang, Chiun-Sheng Huang, Yi-Ting Lin, Ruey-Feng Chang
The shear wave elastography (SWE) uses the acoustic radiation force to measure the stiffness of tissues and is less operator dependent in data acquisition compared to strain elastography. However, the reproducibility of the result is still interpreter dependent. The purpose of this study is to develop a computer-aided diagnosis (CAD) method to differentiate benign from malignant breast tumors using SWE images. After applying the level set method to automatically segment the tumor contour and hue-saturation-value color transformation, SWE features including average tissue elasticity, sectional stiffness ratio, and normalized minimum distance for grouped stiffer pixels are calculated...
March 15, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28341490/validation-of-shear-wave-elastography-cutoff-values-on-the-supersonic-aixplorer-for-practical-clinical-use-in-liver-fibrosis-staging
#4
Manish Dhyani, Joseph R Grajo, Atul K Bhan, Kathleen Corey, Raymond Chung, Anthony E Samir
The purpose of this study was to determine the validity of previously established ultrasound shear wave elastography (SWE) cut-off values (≥F2 fibrosis) on an independent cohort of patients with chronic liver disease. In this cross-sectional study, approved by the institutional review board and compliant with the Health Insurance Portability and Accountability Act, 338 patients undergoing liver biopsy underwent SWE using an Aixplorer ultrasound machine (SuperSonic Imagine, Aix-en-Provence, France). Median SWE values were calculated from sets of 10 elastograms...
March 21, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28335998/point-shear-wave-elastography-to-evaluate-and-monitor-changing-portal-venous-pressure-in-patients-with-decompensated-cirrhosis
#5
Hao Han, Jian Yang, Yu-Zheng Zhuge, Ming Zhang, Min Wu
This study evaluated whether the stiffness of the liver and spleen, measured using the point shear wave elastography (pSWE) technique, correlates with portal venous pressure (PVP) and whether the result extends to estimate the diminishing change in PVP (ΔPVP) in patients with decompensated cirrhosis. We evaluated the data of 67 prospectively enrolled patients who underwent both transjugular intrahepatic portosystemic shunt (TIPS) and pSWE. The stiffness of liver and spleen were evaluated by measuring shear wave velocity (SWV) to determine the statistical correlation with PVP...
March 20, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28299813/improvement-of-liver-stiffness-in-patients-with-hepatitis-c-virus-infection-who-received-direct-acting-antiviral-therapy-and-achieved-sustained-virological-response
#6
Toshifumi Tada, Takashi Kumada, Hidenori Toyoda, Kazuyuki Mizuno, Yasuhiro Sone, Saki Kataoka, Shinichi Hashinokuchi
BACKGROUND AND AIM: There is insufficient research on whether direct-acting antiviral (DAA) therapy can improve liver fibrosis in patients with chronic hepatitis C virus (HCV). We evaluated sequential changes in liver stiffness using shear wave elastography (SWE) in patients with HCV who received DAA therapy. METHODS: A total of 210 patients with HCV who received daclatasvir and asunaprevir therapy and achieved sustained virological response (SVR) were analyzed...
March 15, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28295027/improved-shear-wave-motion-detection-using-coded-excitation-for-transient-elastography
#7
Xiao-Nian He, Xian-Fen Diao, Hao-Ming Lin, Xin-Yu Zhang, Yuan-Yuan Shen, Si-Ping Chen, Zheng-Di Qin, Xin Chen
Transient elastography (TE) is well adapted for use in studying liver elasticity. However, because the shear wave motion signal is extracted from the ultrasound signal, the weak ultrasound signal can significantly deteriorate the shear wave motion tracking process and make it challenging to detect the shear wave motion in a severe noise environment, such as within deep tissues and within obese patients. This paper, therefore, investigated the feasibility of implementing coded excitation in TE for shear wave detection, with the hypothesis that coded ultrasound signals can provide robustness to weak ultrasound signals compared with traditional short pulse...
March 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28292005/current-status-of-musculoskeletal-application-of-shear-wave-elastography
#8
JeongAh Ryu, Woo Kyoung Jeong
Ultrasonography (US) is a very powerful diagnostic modality for the musculoskeletal system due to the ability to perform real-time dynamic high-resolution examinations with the Doppler technique. In addition to acquiring morphologic data, we can now obtain biomechanical information by quantifying the elasticity of the musculoskeletal structures with US elastography. The earlier diagnosis of degeneration and the ability to perform follow-up evaluations of healing and the effects of treatment are possible. US elastography enables a transition from US-based inspection to US-based palpation in order to diagnose the characteristics of tissue...
February 4, 2017: Ultrasonography
https://www.readbyqxmd.com/read/28286981/shear-wave-ultrasound-elastography-of-the-liver-in-normal-weight-and-obese-children
#9
Smita Sane Bailey, Mostafa Youssfi, Mittun Patel, Houchun H Hu, Gabriel Q Shaibi, Richard B Towbin
Background The identification and subsequent management of liver diseases in children is challenging due to the lack of non-invasive imaging biomarkers. Ultrasound shear-wave elastography (US-SWE) is an emerging imaging technique which can quantitatively assess liver stiffness and may be useful as a tool in the management of liver disease in overweight and obese children. Purpose To evaluate US-SWE velocities of the liver in normal-weight and obese children, to correlate US-SWE findings with age and body-mass-index (BMI), and to compare US-SWE values with qualitative assessment (i...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28285729/evaluation-of-post-stroke-spastic-muscle-stiffness-using-shear-wave-ultrasound-elastography
#10
Chueh-Hung Wu, Yu-Chun Ho, Ming-Yen Hsiao, Wen-Shiang Chen, Tyng-Guey Wang
Current clinical evaluations of post-stroke upper limb spasticity are subjective and qualitative. We proposed a quantitative measurement of post-stroke spastic muscle stiffness by using shear-wave ultrasound elastography and tested its reliability. Acoustic radiation force impulse with shear wave velocity (SWV) detection was used to evaluate stiffness of the biceps brachii muscles at 90° and 0° elbow flexion. In 21 control subjects, SWV did not significantly differ between dominant and non-dominant sides at either flexion angle (0°: p = 0...
March 9, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28279018/correlation-of-ultrasound-shear-wave-elastography-with-pathological-analysis-in-a-xenografic-tumour-model
#11
Eli Elyas, Efthymia Papaevangelou, Erwin J Alles, Janine T Erler, Thomas R Cox, Simon P Robinson, Jeffrey C Bamber
The objective of this study was to evaluate the potential value of ultrasound (US) shear wave elastography (SWE) in assessing the relative change in elastic modulus in colorectal adenocarcinoma xenograft models in vivo and investigate any correlation with histological analysis. We sought to test whether non-invasive evaluation of tissue stiffness is indicative of pathological tumour changes and can be used to monitor therapeutic efficacy. US-SWE was performed in tumour xenografts in 15 NCr nude immunodeficient mice, which were treated with either the cytotoxic drug, Irinotecan, or saline as control...
December 2017: Scientific Reports
https://www.readbyqxmd.com/read/28271231/quantitative-assessment-of-muscle-stiffness-with-acoustic-radiation-force-impulse-elastography-after-botulinum-toxin-a-injection-in-children-with-cerebral-palsy
#12
Meltem Ceyhan Bilgici, Tumay Bekci, Yasemin Ulus, Ayhan Bilgici, Leman Tomak, Mustafa Bekir Selcuk
PURPOSE: Our objective in this study was to assess the changes in medial gastrocnemius muscle (GCM) stiffness after botulinum toxin A (BTA) injection in children with cerebral palsy (CP) by using acoustic radiation force impulse (ARFI) elastography and to research the usability of this technique in clinical practice. MATERIALS AND METHODS: Twenty-four spastic lower extremities of 12 children with CP were assessed. BTA injection treatment was applied to the medial GCM...
March 7, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/28268914/shear-wave-elastography-using-wigner-ville-distribution-a-simulated-multilayer-media-study
#13
Pooya Sobhe Bidari, Javad Alirezaie, Jahan Tavakkoli
Shear Wave Elastography (SWE) is a quantitative ultrasound-based imaging modality for distinguishing normal and abnormal tissue types by estimating the local viscoelastic properties of the tissue. These properties have been estimated in many studies by propagating ultrasound shear wave within the tissue and estimating parameters such as speed of wave. Vast majority of the proposed techniques are based on the cross-correlation of consecutive ultrasound images. In this study, we propose a new method of wave detection based on time-frequency (TF) analysis of the ultrasound signal...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268544/comparison-of-viscoelastic-property-characterization-of-plastisol-phantoms-with-magnetic-resonance-elastography-and-high-frequency-rheometry
#14
P M Lefebvre, K Tse Ve Koon, E Brusseau, S Nicolle, J-F Palieme, S A Lambert, D Grenier
This study aims at evaluating Magnetic Resonance Elastography (MRE) as a reliable technique for the characterization of viscoelastic properties of soft tissues. Three phantoms with different concentrations of plastisol and softener were prepared in order to mechanically mimic a broad panel of healthy and pathological soft tissues. Once placed in a MRI device, each sample was excited by a homemade external driver, inducing shear waves within the medium. The storage (G') and loss (G") moduli of each phantom were then reconstructed from MRE acquisitions over a frequency range from 300 to 1,000 Hz, by applying a 2D Helmholtz inversion algorithm...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28267542/comparison-between-acoustic-radiation-force-impulse-quantification-data-and-perfusion-ct-parameters-in-hepatocellular-carcinoma
#15
Michael Esser, Sven Schneeweiß, Manuel Kolb, Mustafa Kurucay, Christer Ruff, Konstantin Nikolaou, Marius Horger
OBJECTIVE: To find out, if ultrasound elastography of hepatocellular carcinoma (HCC) can predict patterns of tumor perfusion in volume perfusion computed tomography (VPCT). MATERIAL AND METHODS: 25 consecutive patients (mean age, 68.9; range, 51-85 years) with liver cirrhosis suspected of HCC underwent VPCT and acoustic radiation force impulse (ARFI) elastography the same day. Quantitative elasticity values were registered, while blood flow (BF), blood volume (BV) and hepatic perfusion index (HPI) of the HCC lesions were calculated...
April 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28267524/the-value-of-shear-wave-elastography-in-the-quantification-of-corpus-cavernosum-penis-rigidity-and-its-alteration-with-age
#16
Ercan Inci, Rustu Turkay, Mustafa Orhan Nalbant, Mustafa Gurkan Yenice, Volkan Tugcu
OBJECTIVE: The goal of this study was to measure corpus cavernosum (CC) penis rigidity with shear wave elastography (SWE) in healthy volunteers and to evaluate the change of rigidity with age. METHODS: SWE was performed in 60 healthy volunteers (age range 20-71, mean 47±12,83 years). Volunteers were divided into 2 groups by age (Group 1 age <50, group 2 age ≥50). We assessed SWE in 3 parts of penis (proximal, middle and glans penis) on both sides of CC. All values of SWE (in kilo Pascal) were noted along with volunteers' ages...
April 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28263409/cryotherapy-induces-an-increase-in-muscle-stiffness
#17
Maxime Point, Gaël Guilhem, François Hug, Antoine Nordez, Alain Frey, Lilian Lacourpaille
Although cold application (i.e., cryotherapy) may be useful to treat sports injuries and to prevent muscle damage, it is unclear whether it has adverse effects on muscle mechanical properties. This study aimed to determine the effect of air-pulsed cryotherapy on muscle stiffness estimated using ultrasound shear wave elastography. Myoelectrical activity, ankle passive torque, shear modulus (an index of stiffness) and muscle temperature of the gastrocnemius medialis were measured before, during an air-pulsed cryotherapy (-30°) treatment of 4 sets of 4 minutes with 1 min recovery in between, and during a 40-min post-cryotherapy period...
March 6, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28262531/non-invasive-assessment-of-liver-fibrosis-in-patients-with-hepatitis-c-shear-wave-elastography-and-colour-doppler-velocity-profile-technique-versus-liver-biopsy
#18
Ehab F Moustafa, Nahed Makhlouf, Sahar M Hassany, Ahmed Helmy, Ahmed Nasr, Moustafa Othman, Hany Seif, Manal Darwish, Howayda Hassan, Mohamed Hessen
BACKGROUND AND STUDY AIMS: Determination of the presence and degree of liver fibrosis is essential for the prognosis and treatment of patients with chronic hepatitis C. Non-invasive methods of assessing fibrosis have been developed to reduce the need for biopsy. We determined the efficacy of shear wave elastography (SWE) and colour Doppler velocity as non-invasive methods for the assessment of liver fibrosis compared to liver biopsy among patients with chronic hepatitis C virus (HCV) infection...
March 2, 2017: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/28258646/assessment-of-tumor-stiffness-with-shear-wave-elastography-in-a-human-prostate-cancer-xenograft-implantation-model
#19
Yiru Wang, Binwei Yao, Hongfei Li, Yan Zhang, Hanjing Gao, Yabin Gao, Ruiyun Peng, Jie Tang
OBJECTIVES: To investigate the stiffness of human prostate cancer in a xenograft implantation model using shear wave elastography and compare the pathologic features of tumors with varying elasticity. METHODS: Human prostate cancer DU-145 cells were injected into 24 nude male mice. The mice were divided into 3 groups according to the time of transplantation (6, 8, and 10 weeks). The volume, elasticity, and Young modulus of tumors were recorded by 2-dimensional sonography and shear wave elastography...
March 4, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28257467/diagnostic-features-of-quantitative-comb-push-shear-elastography-for-breast-lesion-differentiation
#20
Mahdi Bayat, Max Denis, Adriana Gregory, Mohammad Mehrmohammadi, Viksit Kumar, Duane Meixner, Robert T Fazzio, Mostafa Fatemi, Azra Alizad
BACKGROUND: Lesion stiffness measured by shear wave elastography has shown to effectively separate benign from malignant breast masses. The aim of this study was to evaluate different aspects of Comb-push Ultrasound Shear Elastography (CUSE) performance in differentiating breast masses. METHODS: With written signed informed consent, this HIPAA- compliant, IRB approved prospective study included patients from April 2014 through August 2016 with breast masses identified on conventional imaging...
2017: PloS One
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