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Toshiki Hirakawa, Masakazu Yashiro, Yosuke Doi, Haruhito Kinoshita, Tamami Morisaki, Tatsunari Fukuoka, Tsuyoshi Hasegawa, Kenjiro Kimura, Ryosuke Amano, Kosei Hirakawa
Pancreatic ductal adenocarcinoma (PDAC) is characterized by its hypovascularity, with an extremely poor prognosis because of its highly invasive nature. PDAC proliferates with abundant stromal cells, suggesting that its invasive activity might be controlled by intercellular interactions between cancer cells and fibroblasts. Using four PDAC cell lines and two pancreas cancer-associated fibroblasts (CAFs), the expression of insulin-like growth factor-1 (IGF1) and IGF1 receptor (IGF1R) was evaluated by RT-PCR, FACScan, western blot, or ELISA...
2016: PloS One
Kotaro Miura, Kenjiro Kimura, Ryosuke Amano, Sadaaki Yamazoe, Go Ohira, Akihiro Murata, Kohei Nishio, Tsuyoshi Hasegawa, Masakazu Yashiro, Bunzo Nakata, Masaichi Ohira, Kosei Hirakawa
BACKGROUND: Anaplastic pancreatic cancer (APC) cell lines have been scarcely established. METHODS: The morphology, gene expressions, karyotyping and epithelial-mesenchymal transition markers of newly established APC cell lines OCUP-A1 and OCUP-A2 were analyzed. Their abilities of proliferation under normoxia and hypoxia, migration and invasion were compared to 4 commercially available pancreatic ductal adenocarcinoma (PDA) cell lines. Their induction of angiogenesis, stem-like cell population and subcutaneous tumor growth in nude mice were estimated, comparing 2 PDA cell lines examined here...
April 11, 2016: BMC Cancer
Wojciech Witkiewicz, Jan Janusz Gnus, Zuzanna Stankiewicz, Marta Kocot, Marcin Rasiewicz
UNLABELLED: Estimated quantity of homeless people in Poland is about 30.000. Health conditions of homeless depends on poor living conditions, alcohol abuse and lack of medical care. The aim of the study was to present surgical problems of homeless people at St. Brother Albert's Aid Society Shelter in Szczodre. MATERIAL AND METHODS: In years 2009-2011 in St. Brother Albert's Aid Society Shelter in Szczodre 1053 homeless were provided outpatient surgical care. The frequency of occurrence of diseases rated on the basis of the medical examination, medical history and medical records...
September 2013: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
Eric D Amster, Shahar S Fertig, Uri Baharal, Shai Linn, Manfred S Green, Zvi Lencovsky, Rafael S Carel
BACKGROUND: From 2 to 5 December 2010, Israel experienced the most severe forest fire In its history, resulting in the deaths of rescue workers. Little research exists on the health risks to emergency responders during forest fires, and there is no published research to date on occupational health among firefighters in Israel. OBJECTIVES: To describe the exposures experienced by emer gency responders to smoke, fire retardants and stress; the utilization of protective equipment; and the frequency of corresponding symptoms during and following the Carmel Forest fire...
June 2013: Israel Medical Association Journal: IMAJ
George N Oh, James A Ibers
β-UPSe was synthesized from the reaction of U(2)Se(3), P and Se in a CsCl flux in a fused-silica tube. It crystallizes with four formula units in the tetra-gonal space group I4/mmm in the UGeTe structure type. The asymmetric unit comprises one U (site symmetry 4mm), one Se (4mm), and one P (mmm.) atom. The U atom is coordinated in a monocapped square-anti-prismatic arrangement, where the square face is formed by P atoms and the other five vertices are Se atoms. The P site is disordered about a mirror plane, showing half-ocupancy for each of the two resulting P atoms...
December 1, 2011: Acta Crystallographica. Section E, Structure Reports Online
Muhammad Mahmood Anwar, Muhammad Saeed Iqbal, M Nawaz Tahir
The title compound, C(13)H(16)FNO(4), consists of conventional, centrosymmetric carboxyl-ate dimers. These dimers form infinite polymeric chains due to inter-molecular N-H⋯O hydrogen bonding. The 2-fluoro-phenyl unit is disordered over two sets of sites with an ocupancy ratio of 0.915 (3):0.085 (3).
2009: Acta Crystallographica. Section E, Structure Reports Online
Y Chung, Y Kondo, T Sawada, B Nakata, H Tanaka, A Inui, Y Yamashita, K Hirayama, N Onoda, M Sowa
The prognosis of pancreatic cystadenocarcinoma is known to be relatively favorable, unlike poor prognosis of the majority of pancreatic cancers. However, little is known about the pathogenesis and mode of progression of this cancer. We report on a newly established pancreatic cystadenocarcinoma cell line, OCUP-1. Its characteristics were compared to those of cells derived from pancreatic ductal cell carcinoma. OCUP-1 was established by successive culture of cancer cells obtained during an operation for pancreatic cystadenocarcinoma...
June 1994: International Journal of Oncology
Rosemary Cook
No abstract text is available yet for this article.
February 28, 2008: Health Service Journal
O M Vil'ians'ka, V V Rodionova
There is a marked growth of common and occupational morbidity related to the broncho-pulmonary system in Ukraine. This tendency is seen in Dnepropetrovsk region, where an increase in ocupational diseases is observed mainly on mining and smelting plants. Ocupational pulmonary diseases have long asymptomatic period and are diagnostically easy revealed at the late stages. It leads to stable disability and early mortality of these patients. Determination of rate and pecularities of the development of broncho-pulmonary system disorders in employees of plants with unhealthy working conditions as well as timely prophylactic and rehabilitation measures directed to the workers are highly important issue nowadays...
January 2006: Likars'ka Sprava
(no author information available yet)
BACKGROUND: To assist dentists in providing a safe and healthful workplace, the ADA Council on Scientific Affairs developed this advisory statement on the proper use of beryllium-containing alloys in the dental operatory and laboratory. OVERVIEW: Recommendations are made for reducing the potential risk of beryllium exposure for employees working in dental operatories or laboratories who fabricate or manipulate beryllium-containing alloys in dental prostheses. CONCLUSIONS AND PRACTICE IMPLICATIONS: The Council recommends that practitioners adhere to the Ocupational Safety and Health Administration's recommendations for reducing beryllium exposure in the dental operatory and laboratory...
April 2003: Journal of the American Dental Association
L M Frazier, N J Berberich, R Moser, J W Cromer, M A Hitchcock, F M Monteiro, G N Greenberg
To help primary care residency programs develop or improve residency curricula in occupational and environmental medicine, the National Institute for Occupational Safety and Health launched a train-the-trainer initiative. This project was called EPOCH-Envi (Educating Physicians in OCcupational Health and the Environment). From 1990 to 1996, 46 2-day curriculum development workshops were held. These featured (1) guidelines on how to plan, implement, and evaluate a curriculum, (2) continuing education on occupational illnesses and injuries, (3) a worksite or environmental site visit, and (4) information resources...
August 1999: Journal of Occupational and Environmental Medicine
E Strucchi, J González
In this work we describe and analyze today's Latin American occupational reality, according to the world economical context we live in. We mention up-to-date data about employment and unemployment rates, from different countries of Latin America, Europe, and also from Japan. Besides that we have taken into account the technological development and the demographic growth, as essential variables in order to understand the labor phenomenon and its possible prospect, as well as the psychosociological consequences or unemployment...
December 1995: Acta Psiquiátrica y Psicológica de América Latina
(no author information available yet)
No abstract text is available yet for this article.
1980: World Health Organization Technical Report Series
E Sartorelli, R Gori, S Sartorelli, C Buffi
No abstract text is available yet for this article.
September 1986: La Medicina del Lavoro
A Carbajal Ramos, E Núñez González, L Grau Cobos
Carl Langenbuch realized in Germany in 1882, the first cholecystectomy. On this century of experience, the technique has been converted in a classic way. Since 1910, it was converted on the gold standard in the treatment of the cholelithiasis, place that it still conserve. In the last three years, with the apparition of the endoscopy techniques, and the minimum access idea, the way of carrying it out has changed. Merril in United States of America reports 82 cases of cholecystectomy through incisions from 4 to 6 cms of longitude, with good results...
July 1991: Revista de Gastroenterología de México
M P Vessey
The epidemiological literature on the ocupational hazards of anaesthesia which includes some sort of control data has been studied. It provides reasonably convincing evidence of a moderate increase in the risk of spontaneous abortion among exposed females, although it is possible that even this result is attributable to reporting bias. There is no convincing evidence of any other hazard. It has been pointed out by many authors that, even if spontaneous abortion is commoner among those working in anaesthesia, there is no particular reason to believe that this has anything to do with exposure to trace quantities of anaesthetic gases...
May 1978: Anaesthesia
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