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Pelvic exenteration

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https://www.readbyqxmd.com/read/27867338/bladder-leiomyosarcoma-a-rare-but-aggressive-diagnosis
#1
Mathew Fakhoury, Richard R Hwang, Joseph Silletti, Marc A Bjurlin
It remains evident in the literature that leiomyosarcomas of the bladder have continuously been regarded as highly aggressive tumors associated with a poor prognosis. Immediate surgical therapy by radical cystectomy with wide margins is warranted as an effective treatment modality and has been associated with longer survival rates. Herein, we present the case of a high-grade leiomyosarcoma primarily treated with anterior pelvic exenteration and urinary diversion.
October 2016: Current Urology
https://www.readbyqxmd.com/read/27860404/perineal-alveolar-soft-part-sarcoma-treated-by-laparoscopy-assisted-total-pelvic-exenteration-combined-with-pubic-resection
#2
Toshisada Aiba, Keisuke Uehara, Satoshi Tsukushi, Yasushi Yoshino, Tomoki Ebata, Yukihiro Yokoyama, Tsuyoshi Igami, Gen Sugawara, Masato Nagino
A 20-year-old woman with a perineal alveolar soft part sarcoma was referred to our hospital. MRI showed that an irregular oval tumor occupied the perineum. The tumor was contiguous to the vagina, rectum, levator muscle, and pubis and was diagnosed as alveolar soft part sarcoma by transvaginal biopsy. Laparoscopy-assisted total pelvic exenteration combined with a pubic resection was performed, and an R0 resection with a wide margin was achieved. It is well known that only R0 resection improves the outcome of patients with localized alveolar soft part sarcoma...
November 10, 2016: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/27859276/urological-complications-after-cystectomy-as-part-of-pelvic-exenteration-are-higher-than-that-after-cystectomy-for-primary-bladder-malignancy
#3
Kilian G M Brown, Michael J Solomon, Edward R Latif, Cherry E Koh, Arthur Vasilaras, David Eisinger, Paul Sved
BACKGROUND: Total cystectomy and subsequent reconstruction of the urinary tract may be required for primary malignancy of the bladder, or in the context of multi-visceral resection for more advanced pelvic tumors. Complications following urinary diversion are a major source of morbidity, particularly in pelvic exenteration (PE) patients. METHODS: All patients who underwent radical cystectomy alone or during PE at a single tertiary referral centre between 2008 and 2014 were reviewed...
November 18, 2016: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27844048/a-surgical-multi-layer-technique-for-pelvic-reconstruction-after-total-exenteration-using-a-combination-of-pedicled-omental-flap-human-acellular-dermal-matrix-and-autologous-adipose-derived-cells
#4
Anna Myriam Perrone, Alessandra Livi, Milena Fini, Elena Bondioli, Sergio Concetti, Alessio Giuseppe Morganti, Federico Contedini, Pierandrea De Iaco
•A multi-layer technique for reconstruction after pelvic exenteration is proposed.•Human acellular dermal matrix used in reconstruction after total pelvic exenteration.•A reconstructive technique based on human dermis, omental flap and fat is proposed.
November 2016: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/27765044/bladder-chondrosarcoma-plus-urothelial-carcinoma-in-recurred-transitional-cell-carcinoma-of-the-upper-urinary-tract-a-case-report-and-literature-review
#5
Min Hyun Cho, Sung Han Kim, Weon Seo Park, Jae Young Joung, Ho Kyung Seo, Jinsoo Chung, Kang Hyun Lee
BACKGROUND: Sarcomatoid urothelial carcinoma (SUC) is a rare malignant neoplasm of the urinary bladder comprising 0.2-0.6 % of all histological bladder tumor subtypes. It presents as a high-stage malignancy and exhibits aggressive biological behavior, regardless of the treatment employed. It is defined as histologically indistinguishable from sarcoma and as a high-grade biphasic neoplasm with malignant epithelial and mesenchymal components. The mean age of patients presenting with SUC is 66 years, and the male-to-female ratio is 3:1...
October 20, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27760707/survival-after-pelvic-exenteration-for-uterine-malignancy-a-national-cancer-data-base-study
#6
Brandon-Luke L Seagle, Megan Dayno, Anna E Strohl, Stephen Graves, Wilberto Nieves-Neira, Shohreh Shahabi
OBJECTIVE: To determine overall survival (OS) and factors associated with OS after pelvic exenteration for uterine cancer. METHODS: Women with uterine cancer who underwent exenteration (n=1160) were identified from the 1998-2011 National Cancer Data Base. Kaplan-Meier and multivariate Cox proportional-hazards survival analyses were performed to test for associations of potential explanatory variables with OS. Analyzed confounders included age, comorbidity score, insurance status, income, distance from home to treatment center, stage, distant and nodal metastasis, tumor size, surgical margin status, exenteration type, and treatment with radiation and/or chemotherapy...
December 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27749474/palliative-pelvic-exenteration-clinical-outcomes-and-quality-of-life
#7
Aaron J Quyn, Michael J Solomon, Peter M Lee, Tim Badgery-Parker, Lindy M Masya, Jane M Young
BACKGROUND: Locally advanced pelvic malignancy can be associated with disabling symptoms and reduced quality of life. If resectable with clear margins, a pelvic exenteration can offer long-term survival and improved quality of life. Its role in the palliation of symptoms has been described; however, the clinical outcomes and surgical indication are poorly defined. OBJECTIVE: This study describes the clinical and quality-of-life outcomes after palliative pelvic exenteration for advanced pelvic malignancy...
November 2016: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27689067/cytoreductive-surgery-for-men-with-metastatic-prostate-cancer
#8
Nikolas Katelaris, Declan Murphy, Nathan Lawrentschuk, Athos Katelaris, Daniel Moon
BACKGROUND: Cytoreductive surgery for metastatic prostate cancer is an emerging area of interest with a potential upside that includes local control, delayed initiation of hormone therapy, and possibly improved cancer specific survival. In order for radical prostatectomy to be an effective treatment option for men in this group, the benefits must outweigh the surgical morbidity. The aim of this study was to present a case series and assess the literature feasibility of cytoreductive surgery for men with metastatic prostate cancer...
September 2016: Prostate International
https://www.readbyqxmd.com/read/27678666/laparoscopic-supra-levator-total-pelvic-exenteration-in-advanced-case-of-ca-cervix
#9
V Sharma, S Naval, D Kumar, G Joshi, S P Puntambekar
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27678502/effects-of-neoadjuvant-chemotherapy-plus-radical-surgery-as-front-line-treatment-strategy-in-patients-affected-by-figo-stage-iii-cervical-cancer
#10
Violante Di Donato, Michele Carlo Schiavi, Ilary Ruscito, Virginia Sibilla Visentin, Innocenza Palaia, Claudia Marchetti, Margherita Fischetti, Marco Monti, Ludovico Muzii, Pierluigi Benedetti Panici
BACKGROUND: To assess the clinical efficacy and prognostic outcome of neoadjuvant chemotherapy (NACT) plus radical surgery (RS) as front line treatment in patients with FIGO stage III cervical cancer (CC). METHODS: In this retrospective study, 52 FIGO stage III CC patients treated from 2005 to 2015 were included. All patients received platinum-based chemotherapy. Patients reporting clinical response or stable disease after NACT underwent to RS and bilateral systematic pelvic lymphadenectomy with or without aortic lymphadenectomy or anterior exenteration...
September 27, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27629565/selection-process-can-improve-the-outcome-in-locally-advanced-and-recurrent-colorectal-cancer-activity-and-results-of-a-dedicated-multidisciplinary-colorectal-cancer-centre
#11
Christos Kontovounisios, Emile Tan, Nikhil Pawa, Gina Brown, Diana Tait, David Cunningham, Shahnawaz Rasheed, Paris Tekkis
AIM: There is wide disparity in the care of patients with multi-visceral involvement of rectal cancer. The results of treatment of advanced and recurrent colorectal cancer are presented from a centre where a dedicated Multidisciplinary Team (MDT) is central to the management. METHOD: All consecutive MDT referrals between 2010 and 2014 were examined. Analysis was undertaken of the referral pathway, site, selection process, management decision, R0 resection rate, mortality / morbidity / Clavien-Dindo (CD) classification of morbidity, length of stay (LOS), and improvement of quality of life...
September 15, 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/27620339/double-barrelled-wet-colostomy-formation-after-pelvic-exenteration-for-locally-advanced-or-recurrent-rectal-cancer
#12
A L A Bloemendaal, R Kraus, N C Buchs, F C Hamdy, R Hompes, L Cogswell, R J Guy
AIM: In advanced pelvic cancer it may be necessary to perform a total pelvic exenteration. In such cases urinary tract reconstruction is usually achieved with the creation of an ileal conduit with a urinary stoma on the right side of the patient's abdomen and an end colostomy separately on the left. The potential morbidity from a second stoma, may be avoided by the use of a double-barrelled wet colostomy (DBWC), as a single stoma. Another advantage is the possibility to use a vertical rectus abdominis muscle (VRAM) flap for perineal reconstruction...
September 13, 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/27614445/state-of-the-art-treatment-and-novel-agents-in-local-and-distant-recurrences-of-cervical-cancer
#13
Clemens B Tempfer, Matthias W Beckmann
Depending on the stage at initial presentation, cervical cancer will recur in 25-61% of women. Typical manifestations of recurrent cervical cancer include the central pelvis and the pelvic side walls as well as retroperitoneal lymph node basins in the pelvis and the para-aortic region, and - more rarely - supraclavicular lymph nodes. There are no typical symptoms of recurrent cervical cancer. Women with suspected recurrence after cervical cancer based on gynecological examination or organ-specific symptoms must undergo imaging studies and - if technically feasible - biopsy with histological verification, especially in cases of distant metastases, in order to rule out a second primary...
2016: Oncology Research and Treatment
https://www.readbyqxmd.com/read/27585438/severe-fournier-s-gangrene-in-a-patient-with-rectal-cancer-case-report-and-literature-review
#14
Yu Yoshino, Kimihiko Funahashi, Rei Okada, Yasuyuki Miura, Takayuki Suzuki, Takamaru Koda, Kimihiko Yoshida, Junichi Koike, Hiroyuki Shiokawa, Mitsunori Ushigome, Tomoaki Kaneko, Yasuo Nagashima, Mayu Goto, Akiharu Kurihara, Hironori Kaneko
BACKGROUND: Fournier's gangrene in the setting of rectal cancer is rare. Treatment for Fournier's gangrene associated with rectal cancer is more complex than other cases of Fournier's gangrene. We report on a patient with severe Fournier's gangrene in the setting of locally advanced rectal cancer who was treated with a combined modality therapy. CASE PRESENTATION: A 65-year-old man presented with general fatigue and anal pain. The medical and surgical histories were unremarkable...
September 1, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27583267/an-uncommon-case-of-sarcomatoid-urothelial-carcinoma-in-covered-bladder-exstrophy
#15
Carlo Pavone, Marco Vella, Dario Fontana, Cristina Scalici Gesolfo, Sebastiano Oieni, Francesca Toia, Adriana Cordova
We report a case of a woman affected by covered exstrophy, uterus didelphys and external genital malformation presenting with advanced bladder cancer. After neoadjuvant therapy and anterior pelvic exenteration, the abdominal wall was reconstructed with a pedicled myocutaneous muscle-sparing vastus lateralis flap.
2016: Case Reports in Plastic Surgery & Hand Surgery
https://www.readbyqxmd.com/read/27559684/cost-effectiveness-of-pelvic-exenteration-for-locally-advanced-malignancy
#16
C E Koh, T Badgery-Parker, G Salkeld, J M Young, A G Heriot, M J Solomon
BACKGROUND: The rising cost of healthcare is well documented. The purpose of this study was to determine the cost-effectiveness of pelvic exenteration (PE). METHODS: Consecutive patients referred for consideration of PE between 2008 and 2011 were recruited into a prospective non-randomized study that compared quality of life (QoL) between patients who did or did not undergo PE. Information on QoL and cost (in Australian dollars, AUD) was collected at baseline, during admission and up to 24 months after discharge...
October 2016: British Journal of Surgery
https://www.readbyqxmd.com/read/27537531/a-systematic-review-to-assess-resection-margin-status-after-abdominoperineal-excision-and-pelvic-exenteration-for-rectal-cancer
#17
Constantinos Simillis, Daniel L H Baird, Christos Kontovounisios, Nikhil Pawa, Gina Brown, Shahnawaz Rasheed, Paris P Tekkis
OBJECTIVE: The aim of this study was to assess resection margin status and its impact on survival after abdominoperineal excision and pelvic exenteration for primary or recurrent rectal cancer. SUMMARY OF BACKGROUND DATA: Resection margin is important to guide therapy and to evaluate patient prognosis. METHODS: A meta-analysis was performed to assess the impact of resection margin status on survival, and a regression analysis to analyze positive resection margin rates reported in the literature...
August 17, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/27505111/outcomes-of-pelvic-exenteration-with-en-bloc-partial-or-complete-pubic-bone-excision-for-locally-advanced-primary-or-recurrent-pelvic-cancer
#18
Kirk K S Austin, Andrew J Herd, Michael J Solomon, Ken Ly, Peter J Lee
INTRODUCTION: Neoplasms infiltrating the pubic bone have until recently been considered a contraindication to surgery. Paucity of existing published data in regard to surgical techniques and outcomes exist. OBJECTIVE: This study aims to address outcomes of our recently published technique for en bloc composite pubic bone excision during pelvic exenteration. DESIGN: A prospective database was reviewed to identify patients who underwent a partial or complete pubic bone composite excision over a 12-year period...
September 2016: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27460130/laparoscopic-total-pelvic-exenteration-using-transanal-minimal-invasive-surgery-technique-with-en-bloc-bilateral-lymph-node-dissection-for-advanced-rectal-cancer
#19
Kengo Hayashi, Masanori Kotake, Daiki Kakiuchi, Sho Yamada, Masahiro Hada, Yosuke Kato, Chikashi Hiranuma, Kaeko Oyama, Takuo Hara
A 59-year-old man presenting with fecal occult blood visited our hospital. He was diagnosed with advanced lower rectal cancer, which was contiguous with the prostate and the left seminal vesicle. There were no metastatic lesions with lymph nodes or other organs. We performed laparoscopic total pelvic exenteration (LTPE) using transanal minimal invasive surgery technique with bilateral en bloc lateral lymph node dissection for advanced primary rectal cancer after neoadjuvant chemoradiotherapy. The total operative time was 760 min, and the estimated blood loss was 200 ml...
December 2016: Surgical Case Reports
https://www.readbyqxmd.com/read/27434623/evidence-for-the-use-of-robotically-assisted-surgery-in-gynecologic-cancers
#20
Charlotte Ngô, Caroline Cornou, Léa Rossi, Anne-Sophie Bats, Chérazade Bensaid, Albane Frati, Claude Nos, Fabrice Lécuru
PURPOSE OF REVIEW: Robotically assisted laparoscopy has been introduced in the armamentarium of gynaecologic oncology surgeons. A lot of studies compared robotic surgery and laparotomy when the real issue is to demonstrate the interest and added value of robotically assisted laparoscopy versus standard laparoscopy. In this review, we will describe the most meaningful indications and advantages of robotically assisted laparoscopy in gynaecologic oncology. RECENT FINDINGS: The learning curve for advanced procedures in robot-assisted laparoscopy is shorter and easier than with the standard laparoscopy, especially for beginners...
September 2016: Current Opinion in Oncology
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