Daisuke Kobayashi, Yusuke Inoue, Ryosuke Suzuki, Mami Matsuda, Hiroshi Shimoda, Astri Nur Faizah, Yoshihiro Kaku, Keita Ishijima, Yudai Kuroda, Kango Tatemoto, Milagros Virhuez-Mendoza, Michiko Harada, Ayano Nishino, Mizue Inumaru, Kenzo Yonemitsu, Ryusei Kuwata, Ai Takano, Mamoru Watanabe, Yukiko Higa, Kyoko Sawabe, Ken Maeda, Haruhiko Isawa
During their blood-feeding process, ticks are known to transmit various viruses to vertebrates, including humans. Recent viral metagenomic analyses using next-generation sequencing (NGS) have revealed that blood-feeding arthropods like ticks harbor a large diversity of viruses. However, many of these viruses have not been isolated or cultured, and their basic characteristics remain unknown. This study aimed to present the identification of a difficult-to-culture virus in ticks using NGS and to understand its epidemic dynamics using molecular biology techniques...
May 7, 2024: Proceedings of the National Academy of Sciences of the United States of America