Kirsten E Smith, Jeffrey M Rogers, Abhisheak Sharma, Christopher R McCurdy, Stephanie T Weiss, Kelly E Dunn, Jeffrey D Feldman, Michelle A Kuntz, Sushobhan Mukhopadhyay, Kanumuri Siva Rama Raju, Richard C Taylor, David H Epstein
INTRODUCTION: Use of kratom has outpaced systematic study of its effects, with most studies reliant on retrospective self-report. METHODS: We aimed to assess acute effects following kratom use in adults who use regularly, and quantify alkaloids in the products, urine, and plasma. Between July and November 2022, 10 adults came to our clinic and orally self-administered their typical kratom dose; blinding procedures were not used. Physiological measures included blood pressure, respiratory rate, heart rate, pulse oximetry, temperature, and pupil diameter...
January 4, 2024: Journal of Addiction Medicine