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https://www.readbyqxmd.com/read/29244672/a-short-femoral-stem-in-revision-total-hip-replacement-an-alternative-solution-for-prosthetic-fracture-a-case-report
#1
Paul Y F Lee, David J Woodnutt, David M Golding
CASE: A 65-year-old farmer re-presented 5 years after sustaining a midshaft prosthetic fracture of a previous long-stem revision hip replacement. He was treated with a proximal-loading short femoral stem, and did not require an extended trochanteric osteotomy for removal of the well-fixed distal implant. He was able to fully bear weight immediately postoperatively, and he remained pain-free without functional loss at the 42-month follow-up. CONCLUSION: This use of a modern short-stem prosthesis is a treatment option for a potentially complex prosthetic fracture in highly active patients, and it reduces intraoperative complexity...
April 2017: JBJS Case Connector
https://www.readbyqxmd.com/read/29206104/science-forum-the-human-cell-atlas
#2
Aviv Regev, Sarah A Teichmann, Eric S Lander, Ido Amit, Christophe Benoist, Ewan Birney, Bernd Bodenmiller, Peter J Campbell, Piero Carninci, Menna Clatworthy, Hans Clevers, Bart Deplancke, Ian Dunham, James Eberwine, Roland Eils, Wolfgang Enard, Andrew Farmer, Lars Fugger, Berthold Göttgens, Nir Hacohen, Muzlifah Haniffa, Martin Hemberg, Seung K Kim, Paul Klenerman, Arnold Kriegstein, Ed Lein, Sten Linnarsson, Emma Lundberg, Joakim Lundeberg, Partha Majumder, John C Marioni, Miriam Merad, Musa Mhlanga, Martijn Nawijn, Mihai Netea, Garry Nolan, Dana Pe'er, Anthony Phillipakis, Chris P Ponting, Stephen R Quake, Wolf Reik, Orit Rozenblatt-Rosen, Joshua R Sanes, Rahul Satija, Ton N Schumacher, Alex K Shalek, Ehud Shapiro, Padmanee Sharma, Jay W Shin, Oliver Stegle, Michael R Stratton, Michael J T Stubbington, Fabian J Theis, Matthias Uhlen, Alexander van Oudenaarden, Allon Wagner, Fiona M Watt, Jonathan S Weissman, Barbara J Wold, Ramnik J Xavier, Nir Yosef
The recent advent of methods for high-throughput single-cell molecular profiling has catalyzed a growing sense in the scientific community that the time is ripe to complete the 150-year-old effort to identify all cell types in the human body. The Human Cell Atlas Project is an international collaborative effort that aims to define all human cell types in terms of distinctive molecular profiles (such as gene expression profiles) and to connect this information with classical cellular descriptions (such as location and morphology)...
December 5, 2017: ELife
https://www.readbyqxmd.com/read/29178061/a-framework-of-connections-between-soil-and-people-can-help-improve-sustainability-of-the-food-system-and-soil-functions
#3
REVIEW
Bruce C Ball, Paul R Hargreaves, Christine A Watson
Globally soil quality and food security continue to decrease indicating that agriculture and the food system need to adapt. Improving connection to the soil by knowledge exchange can help achieve this. We propose a framework of three types of connections that allow the targeting of appropriate messages to different groups of people. Direct connection by, for example, handling soil develops soil awareness for management that can be fostered by farmers joining groups on soil-focused farming such as organic farming or no-till...
November 24, 2017: Ambio
https://www.readbyqxmd.com/read/29169273/evaluating-the-implementation-of-a-farmers-market-targeting-wic-fmnp-participants
#4
Lanae Ball, Amy McCauley, Tracey Paul, Kenneth Gruber, Lauren Haldeman, Jigna Dharod
The present study planned and implemented a new farmers' market (FM) at a WIC (Special Supplemental Nutrition Program for Women, Infants, and Children) clinic in North Carolina, of which WIC FM Nutrition Program (FMNP) participants were the main priority population. The purpose of this FM was to provide convenience and improve access to locally grown fresh fruits and vegetables in the community and to increase the FMNP coupon redemption rate. The main objective of this study was to describe the overall process and key strategies involved in implementing a FM at a WIC clinic...
November 1, 2017: Health Promotion Practice
https://www.readbyqxmd.com/read/29167886/payment-reform-to-enhance-collaboration-of-primary-care-and-cardiology-a-review
#5
Steven A Farmer, Paul N Casale, Linda D Gillam, John S Rumsfeld, Shari Erickson, Neil M Kirschner, Kevin de Regnier, Bruce R Williams, R Shawn Martin, Mark B McClellan
Importance: The US health care system faces an unsustainable trajectory of high costs and inconsistent outcomes. The fee-for-service payment model has contributed to inefficiency, and new payment methods are a promising approach to improving value. Health reforms are needed to increase patient access, reduce costs, and improve health care quality, and the landmark Medicare Access and CHIP Reauthorization Act presents a roadmap for reform. The product of a collaboration between primary care and cardiology clinicians, this review describes a conceptual approach to delivery and payment reforms that aim to better support primary care-cardiology comanagement of chronic cardiovascular disease (CVD)...
November 22, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29163604/root-traits-enhancing-rice-grain-yield-under-alternate-wetting-and-drying-condition
#6
Nitika Sandhu, Sushil R Subedi, Ram B Yadaw, Bedanand Chaudhary, Hari Prasai, Khandakar Iftekharuddaula, Tho Thanak, Vathany Thun, Khushi R Battan, Mangat Ram, Challa Venkateshwarlu, Vitaliano Lopena, Paquito Pablico, Paul C Maturan, Ma Teresa Sta Cruz, K Anitha Raman, Bertrand Collard, Arvind Kumar
Reducing water requirements and lowering environmental footprints require attention to minimize risks to food security. The present study was conducted with the aim to identify appropriate root traits enhancing rice grain yield under alternate wetting and drying conditions (AWD) and identify stable, high-yielding genotypes better suited to the AWD across variable ecosystems. Advanced breeding lines, popular rice varieties and drought-tolerant lines were evaluated in a series of 23 experiments conducted in the Philippines, India, Bangladesh, Nepal and Cambodia in 2015 and 2016...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29156248/the-symbolic-violence-of-outbreak-a-mixed-methods-quasi-experimental-impact-evaluation-of-social-protection-on-ebola-survivor-wellbeing
#7
Eugene T Richardson, J Daniel Kelly, Osman Sesay, Michael D Drasher, Ishaan K Desai, Raphael Frankfurter, Paul E Farmer, Mohamed Bailor Barrie
Despite over 28,000 reported cases of Ebola virus disease (EVD) in the 2013-16 outbreak in West Africa, we are only beginning to trace the complex biosocial processes that have promoted its spread. Important questions remain, including the effects on survivors of clinical sequelae, loss of family and livelihood, and other psychological and social trauma. Another poorly understood question is what effect social protection and job creation programs have had on survivors' wellbeing. Several clinical and social protection programs have been developed to respond to the needs of EVD survivors; however, little in the way of impact evaluation has taken place...
November 11, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/29152316/seroepidemiology-and-assessment-of-risk-factors-for-the-spread-of-avian-influenza-in-birds-in-two-nigerian-states
#8
Musa Ibrahim Waziri, Paul A Abdu, Lawal Sa'idu, Mohammed Bello
Despite modified stamping out eradication policy adopted in Nigeria, there was resurgence in 2015 of highly pathogenic avian influenza (HPAI) H5N1 with greater infectivity. A survey of the risk of spread of HPAI in two HPAI-infected and -uninfected Nigerian states were studied. A cross-sectional study to detect avian influenza (AI) H5 antibodies was conducted using haemagglutination inhibition (HI) test and enzyme-linked immunosorbent assay (ELISA). A total of 950 birds' sera were tested for AI H5 antibodies...
November 2017: Veterinary Medicine and Science
https://www.readbyqxmd.com/read/29119300/longitudinal-outcomes-of-children-with-pediatric-autoimmune-neuropsychiatric-disorder-associated-with-streptococcal-infections-pandas
#9
Jill Leon, Rebecca Hommer, Paul Grant, Cristan Farmer, Precilla D'Souza, Riley Kessler, Kyle Williams, James F Leckman, Susan Swedo
Little is known about the natural history of children with pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS). This study prospectively followed 33 children with PANDAS for up to 4.8 years (mean 3.3 ± 0.7 years) after enrollment in a 24-week randomized, double-blind, placebo-controlled trial of intravenous immunoglobulin (IVIG) (N = 35). Fourteen of eighteen children randomized to placebo received open label IVIG 6 weeks after the blinded infusion, so follow-up results reported below largely reflect outcomes in a population of children who received at least one dose of IVIG...
November 8, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29109569/-the-farmer-and-the-cowman-should-be-friends-surviving-a-curricular-revision-through-interprofessional-cooperation
#10
Timothy J Bloom, V Paul DiMondi
No abstract text is available yet for this article.
September 2017: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/29103648/adapting-crop-rotations-to-climate-change-in-regional-impact-modelling-assessments
#11
Edmar I Teixeira, John de Ruiter, Anne-Gaelle Ausseil, Adam Daigneault, Paul Johnstone, Allister Holmes, Andrew Tait, Frank Ewert
The environmental and economic sustainability of future cropping systems depends on adaptation to climate change. Adaptation studies commonly rely on agricultural systems models to integrate multiple components of production systems such as crops, weather, soil and farmers' management decisions. Previous adaptation studies have mostly focused on isolated monocultures. However, in many agricultural regions worldwide, multi-crop rotations better represent local production systems. It is unclear how adaptation interventions influence crops grown in sequences...
November 2, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29097432/endoscopic-ultrasound-fine-needle-aspiration-by-experienced-pulmonologists-a-cusum-analysis
#12
Paul Leong, Sheetal Deshpande, Louis B Irving, Philip G Bardin, Michael W Farmer, Barton R Jennings, Daniel P Steinfort
Endobronchial ultrasound transbronchial needle aspiration (EBUS TBNA) is an established, minimally invasive way to sample intrathoracic abnormalities. The EBUS scope can be passed into the oesophagus to perform endoscopic ultrasound with bronchoscope-guided fine-needle aspiration (EUS-B-FNA). In cases of suspected lung cancer, a combination of the two techniques is now recommended by consensus guidelines. EBUS TBNA is usually performed by pulmonologists; however, the learning curve for EUS-B-FNA, which may be performed during the same procedure, has not been described...
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29095802/occupational-exposure-to-vapor-gas-dust-and-fumes-in-a-cohort-of-rural-adults-in-iowa-compared-with-a-cohort-of-urban-adults
#13
COMPARATIVE STUDY
Brent C Doney, Paul K Henneberger, Michael J Humann, Xiaoming Liang, Kevin M Kelly, Jean M Cox-Ganser
PROBLEM/CONDITION: Many rural residents work in the field of agriculture; however, employment in nonagricultural jobs also is common. Because previous studies in rural communities often have focused on agricultural workers, much less is known about the occupational exposures in other types of jobs in rural settings. Characterizing airborne occupational exposures that can contribute to respiratory diseases is important so that differences between rural and urban working populations can be assessed...
November 3, 2017: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/29089292/tapering-practices-of-strongman-athletes-test-retest-reliability-study
#14
Paul W Winwood, Hayden J Pritchard, Justin Wl Keogh
BACKGROUND: Little is currently known about the tapering practices of strongman athletes. We have developed an Internet-based comprehensive self-report questionnaire examining the training and tapering practices of strongman athletes. OBJECTIVE: The objective of this study was to document the test-retest reliability of questions associated with the Internet-based comprehensive self-report questionnaire on the tapering practices of strongman athletes. The information will provide insight on the reliability and usefulness of the online questionnaire for use with strongman athletes...
October 31, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/29081595/the-effect-of-expected-value-on-attraction-effect-preference-reversals
#15
George D Farmer, Paul A Warren, Wael El-Deredy, Andrew Howes
The attraction effect shows that adding a third alternative to a choice set can alter preference between the original two options. For over 30 years, this simple demonstration of context dependence has been taken as strong evidence against a class of parsimonious value-maximising models that evaluate alternatives independently from one another. Significantly, however, in previous demonstrations of the attraction effect alternatives are approximately equally valuable, so there was little consequence to the decision maker irrespective of which alternative was selected...
October 2017: Journal of Behavioral Decision Making
https://www.readbyqxmd.com/read/29058943/a-re-examination-of-bias-in-human-randomness-perception
#16
Paul A Warren, Umberto Gostoli, George D Farmer, Wael El-Deredy, Ulrike Hahn
Human randomness perception is commonly described as biased. This is because when generating random sequences humans tend to systematically under- and overrepresent certain subsequences relative to the number expected from an unbiased random process. In a purely theoretical analysis we have previously suggested that common misperceptions of randomness may actually reflect genuine aspects of the statistical environment, once cognitive constraints are taken into account which impact on how that environment is actually experienced (Hahn & Warren, Psychological Review, 2009)...
October 23, 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/29045303/riluzole-serum-concentration-in-pediatric-patients-treated-for-obsessive-compulsive-disorder
#17
Paul Grant, Cristan Farmer, Jane Song, Timothy Kish, Susan Swedo
PURPOSE/BACKGROUND: The goals of this study were to determine whether pediatric serum concentration of riluzole is similar to that observed in adults and to determine whether riluzole serum concentration is associated with adverse effects or efficacy in children and adolescents with treatment-refractory obsessive-compulsive disorder. METHODS/PROCEDURES: Data were drawn from previously published studies: 1 open-label trial and 1 randomized controlled trial with an open-label extension phase...
December 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29032993/alleviating-the-access-abyss-in-palliative-care-and-pain-relief-an-imperative-of-universal-health-coverage-the-lancet-commission-report
#18
REVIEW
Felicia Marie Knaul, Paul E Farmer, Eric L Krakauer, Liliana De Lima, Afsan Bhadelia, Xiaoxiao Jiang Kwete, Héctor Arreola-Ornelas, Octavio Gómez-Dantés, Natalia M Rodriguez, George A O Alleyne, Stephen R Connor, David J Hunter, Diederik Lohman, Lukas Radbruch, María Del Rocío Sáenz Madrigal, Rifat Atun, Kathleen M Foley, Julio Frenk, Dean T Jamison, M R Rajagopal
No abstract text is available yet for this article.
October 11, 2017: Lancet
https://www.readbyqxmd.com/read/28952988/in-reply-to-eichbaum
#19
Joseph J Rhatigan, Paul E Farmer
No abstract text is available yet for this article.
October 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28935869/deoxyribonuclease-1-reduces-pathogenic-effects-of-cigarette-smoke-exposure-in-the-lung
#20
Paul T King, Roleen Sharma, Kim M O'Sullivan, Judy Callaghan, Lovisa Dousha, Belinda Thomas, Saleela Ruwanpura, Steven Lim, Michael W Farmer, Barton R Jennings, Michaela Finsterbusch, Gavin Brooks, Stavros Selemidis, Gary P Anderson, Stephen R Holdsworth, Philip G Bardin
Our aim was to investigate if deoxyribonuclease (DNase) 1 is a potential therapeutic agent to reduce pathogenic effects of cigarette smoke exposure in the lung. Cigarette smoke causes protease imbalance with excess production of proteases, which is a key process in the pathogenesis of emphysema. The mechanisms responsible for this effect are not well-defined. Our studies demonstrate both in vitro and in vivo that cigarette smoke significantly increases the expression of neutrophil and macrophage extracellular traps with coexpression of the pathogenic proteases, neutrophil elastase and matrix metalloproteinases 9 and 12...
September 21, 2017: Scientific Reports
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