keyword
https://read.qxmd.com/read/38732333/primary-cardiac-intimal-sarcoma-multi-layered-strategy-and-core-role-of-mdm2-amplification-co-amplification-and-mdm2-immunostaining
#1
REVIEW
Claudiu Nistor, Mara Carsote, Anca-Pati Cucu, Mihaela Stanciu, Florina Ligia Popa, Adrian Ciuche, Mihai-Lucian Ciobica
Primary cardiac tumours are relatively uncommon (75% are benign). Across the other 25%, representing malignant neoplasia, sarcomas account for 75-95%, and primary cardiac intimal sarcoma (PCIS) is one of the rarest findings. We aimed to present a comprehensive review and practical considerations from a multidisciplinary perspective with regard to the most recent published data in the specific domain of PCIS. We covered the issues of awareness amid daily practice clinical presentation to ultra-qualified management in order to achieve an adequate diagnosis and prompt intervention, also emphasizing the core role of MDM2 immunostaining and MDM2 genetic analysis...
April 28, 2024: Diagnostics
https://read.qxmd.com/read/38731255/secondary-microsurgical-reconstruction-of-the-cervical-esophagus-safer-flaps-and-practical-tips-in-a-challenging-situation
#2
JOURNAL ARTICLE
Vittorio Ramella, Andrea Ferrari, Federico Cesare Novati, Zoran Marij Arnež, Grace Marchi, Agostino Rodda, Stefano Bottosso, Giovanni Papa
Background : Cervical esophageal reconstruction is vital to improve the quality of life in cancer surgery patients. Microsurgery is crucial in providing vascularized tissue for defect repair, particularly in secondary cases with a higher risk of failure due to larger defects and damage from previous surgery and radiotherapy. The purpose of this study was to describe the clinical characteristics of a series of patients who underwent secondary repair of esophageal defects and provide practical information for the management and treatment of such cases based on the authors' experience and the literature review...
May 6, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38730690/the-impact-of-the-covid-19-pandemic-on-time-to-treatment-in-surgical-oncology-a-national-registry-study-in-the-netherlands
#3
JOURNAL ARTICLE
Roos M G van Vuren, Yester F Janssen, Rianne N M Hogenbirk, Michelle R de Graaff, Rinske van den Hoek, Schelto Kruijff, David J Heineman, Willemijn Y van der Plas, Michel W J M Wouters
UNLABELLED: To avoid delay in oncological treatment, a 6-weeks norm for time to treatment has been agreed on in The Netherlands. However, the impact of the COVID-19 pandemic on health systems resulted in reduced capacity for regular surgical care. In this study, we investigated the impact of the COVID-19 pandemic on time to treatment in surgical oncology in The Netherlands. METHODS: A population-based analysis of data derived from five surgical audits, including patients who underwent surgery for lung cancer, colorectal cancer, upper gastro-intestinal, and hepato-pancreato-biliary (HPB) malignancies, was performed...
April 29, 2024: Cancers
https://read.qxmd.com/read/38730489/discharge-within-24%C3%A2-h-transvaginal-natural-orifice-transluminal-endoscopic-surgery-more-suitable-for-ambulatory-surgery-in-gynecology-procedures-a-retrospective-study
#4
JOURNAL ARTICLE
Fangyuan Zhong, Yueyu Dai, Xiaoyan Liao, Wei Cheng, Ying Liu, Yan Liu, Ziru Yan, Yonghong Lin, Xiaoqin Gan
BACKGROUND: Natural orifice transluminal endoscopic surgery (NOTES) is an achievement in the field of minimally invasive surgery. However, the vantage point of vaginal natural orifice transluminal endoscopic surgery (vNOTES) in gynecologicalprocedures remains unclear. The main purpose of this study was to compare vNOTES with laparo-endoscopic single-site surgery, and to determine which procedure is more suitable for ambulatory surgery in gynecologic procedures. METHODS: This retrospective observational study was conducted at the Department of Gynecology, Chengdu Women's and Children's Central Hospital...
May 10, 2024: BMC Women's Health
https://read.qxmd.com/read/38730129/secondary-ileal-lymph-node-metastases-from-rectal-cancer-a-case-report
#5
JOURNAL ARTICLE
Makoto Ando, Nobuyuki Takemura, Ryo Oikawa, Yuhi Yoshizaki, Fuyuki Inagaki, Fuminori Mihara, Tomomichi Kiyomatsu, Kazuhiko Yamada, Norihiro Kokudo
BACKGROUND: Colorectal cancer can invade adjacent organs, but rarely metastasizes to the regional lymph nodes (LNs) of the invaded organ. Herein, we report a case of rectal cancer invading the ileum and metastasized to the regional ileal LNs. CASE PRESENTATION: A 77-year-old male presented abdominal pain and anorexia, diagnosed with rectal cancer invading the small intestine and concurrently metastasized to the regional LN of the intestine and liver. High anterior resection and partial resection of the small intestine was performed, then, the patient was referred to our hospital for chemotherapy...
May 11, 2024: Surgical Case Reports
https://read.qxmd.com/read/38728484/multiple-sarcomatoid-carcinomas-in-the-small-intestine-with-perforation-a-case-report-and-literature-review
#6
REVIEW
Xujie Wang, Huan Zhang, Long Li, Jixin Fu, Xinjian Wang
RATIONALE: Sarcomatoid carcinoma of the small intestine is an exceedingly rare and aggressive malignancy, often diagnosed at advanced stages with a poor prognosis. This study documents a detailed case of sarcomatoid carcinoma of the small intestine, highlighting the diagnostic challenges and treatment approaches, underscored by a comprehensive review of related literature. Given the rarity of this condition, our report aims to enrich the existing diagnostic and treatment frameworks for this malignancy, emphasizing the necessity for early detection and intervention strategies...
May 10, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38724857/non-intestinal-type-adenocarcinoma-of-the-nasal-cavity-and-paranasal-sinuses-an-analysis-of-clinical-characteristics-and-prognosis
#7
JOURNAL ARTICLE
Jing Zhou, Xinming Zhao, Lifei Feng, Wen Gao, Xiaohong Chen, Jugao Fang, Zhigang Huang, Yang Zhang
BACKGROUND: Non‑intestinal adenocarcinoma of the nasal cavity and paranasal sinuses (non‑ITAC) is a heterogeneous tumour that has rarely been reported in previous studies. We compared and analysed the symptoms, radiographic and pathological features, treatment methods, and prognosis of patients with low-grade (G1) and high-grade (G3) tumours. METHODS: This was a retrospective study included 22 patients with pathologically confirmed non-ITAC of the nasal cavity and paranasal sinuses who were treated between January 2008 and December 2021 at a single centre...
May 9, 2024: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38724058/perfusion-outcomes-with-near-infrared-indocyanine-green-imaging-system-in-laparoscopic-total-mesorectal-excision-for-mid-rectal-or-low-rectal-cancer-poster-a-study-protocol
#8
JOURNAL ARTICLE
Liting Sun, Jiale Gao, Guocong Wu, Cong Meng, Zhengyang Yang, Pengyu Wei, Hongwei Yao, Zhongtao Zhang
INTRODUCTION: Anastomotic leakage (AL) is defined as the failure of complete healing or disruption of the anastomosis subsequent to rectal cancer surgery, resulting in the extravasation of intestinal contents into the intra-abdominal or pelvic cavity. It is a serious complication of rectal cancer surgery, accounting for a considerable increase in morbidity and mortality. The use of fluorescence imaging technology in surgery allows surgeons to better evaluate blood perfusion. However, the conclusions of some existing studies are not consistent, so a consensus on whether the near-infrared indocyanine green (NIR-ICG) imaging system can reduce the incidence of AL is needed...
May 9, 2024: BMJ Open
https://read.qxmd.com/read/38723240/time-to-operation-and-mortality-risk-in-elderly-patients-with-intestinal-fistula-not-too-early-and-not-too-late
#9
JOURNAL ARTICLE
Rahim Hirani, Abbas Smiley, Rifat Latifi
INTRODUCTION: This study aimed to ascertain the risk factors contributing to in-patient mortality in elderly patients 65 years and older who were admitted emergently, diagnosed with intestinal fistula, and underwent surgery. MATERIALS AND METHODS: Data were extracted from the National Inpatient Sample (NIS) spanning the years 2005-2014. Multivariable logistic regression and a generalized additive model (GAM) were employed to investigate predictors of mortality. Continuous variables are presented as mean values with standard deviations (SD)...
May 9, 2024: Surgical Technology International
https://read.qxmd.com/read/38722424/aso-author-reflections-radio-guided-surgery-in-small-intestine-neuroendocrine-tumors-new-probe-new-perspectives
#10
JOURNAL ARTICLE
Emilio Bertani, Francesco Mattana, Francesco Collamati, Mahila E Ferrari, Vincenzo Bagnardi, Samuele Frassoni, Eleonora Pisa, Riccardo Mirabelli, Silvio Morganti, Maria Danieli, Nicola Fazio, Uberto Fumagalli Romario, Francesco Ceci
No abstract text is available yet for this article.
May 9, 2024: Annals of Surgical Oncology
https://read.qxmd.com/read/38721257/cecal-volvulus-secondary-to-mesodiverticular-band
#11
Brice Blum, Arthur D Grimes, Hannah L Carroll, Gregory R Stettler
Meckel's diverticula are one of the most common gastrointestinal anomalies, yet mesodiverticular bands are rare. The treatment of these bands commonly requires surgery. A healthy patient in his 20s presented to the emergency department with a 1 day history of acute onset abdominal pain. Computed tomography imaging was consistent with volvulus of the large intestine. In the operating room, the patient was noted to have a band between the ileal mesentery and tip of a Meckel's diverticulum, consistent with a mesodivertiular band, through which cecum had volvulized...
May 2024: Journal of Surgical Case Reports
https://read.qxmd.com/read/38721256/small-intestine-metastasis-from-endometrial-carcinoma-initially-presented-as-enterocutaneous-fistula-a-case-report-and-literature-review
#12
Andrej Nikolovski, Nimetula Limani, Aleksandra Ristova Tancheva, Antonela Manasievska Bogoevska, Blagica Krsteska
Although endometrial cancer is the fourth most common malignancy among women, it rarely metastasizes to the small intestine. Cases of endometrial recurrence to the intestine clinically present with secondary anemia, melena, abdominal cramps, and epigastric pain. Only a dozen cases are reported in the literature, but none presented with an enterocutaneous fistula. In this report, we present a case of an 88-year-old female patient previously treated for endometrial adenocarcinoma with surgery and adjuvant radiotherapy...
May 2024: Journal of Surgical Case Reports
https://read.qxmd.com/read/38719378/intestinal-transplantation-include-the-spleen-with-intestinal-graft
#13
REVIEW
Rei Matsumoto, Tomoaki Kato
The traditional procedure for multivisceral transplant (MVT) is to transplant the stomach, pancreas, intestine, and liver en bloc. During surgery, the native spleen is routinely removed from the recipient, and it usually creates more space in the abdomen to insert the allogeneic graft. Thus, recipients often become asplenic after MVT. Considering all of the risks and benefits, we advocate that temporary transplant of the donor spleen could be the best option for MVT recipients; it could potentially reduce the rate of intestinal allograft rejection without increasing the risk for graft-versus-host disease...
June 2024: Gastroenterology Clinics of North America
https://read.qxmd.com/read/38719182/assessment-of-the-quality-of-life-of-patients-with-inflammatory-bowel-disease
#14
JOURNAL ARTICLE
María Del Mar Calvo Bernal, Elena Pérez Campos, Adrián Aparicio Mota, Álvaro Hernández Martínez
INTRODUCTION: Ulcerative colitis (UC) and Crohn's disease (CD) are diseases that cause a significant impact on patients' quality of life.The aim of this study is to assess the impact of inflammatory bowel disease (IBD) on health-related quality of life (HRQoL). MATERIAL AND METHODS: Observational, descriptive, cross-sectional study, carried out at Torrecárdenas Hospital (Almería). Patients over 14 years of age diagnosed with CD or UC were included.For the assessment of HRQoL, the reduced 9-item IBDQ-9 questionnaire was used...
May 6, 2024: Gastroenterología y Hepatología
https://read.qxmd.com/read/38717841/infliximab-tissue-concentrations-in-patients-with-stable-ulcerative-colitis-are-correlated-with-more-durable-infliximab-associated-disease-remission
#15
JOURNAL ARTICLE
John Choi, Qian Wang, Melanie Beaton, Richard B Kim, Reena Khanna, Aze Wilson
BACKGROUND: We aimed to determine the correlation between tissue and plasma infliximab concentrations in an outpatient ulcerative colitis (UC) cohort based on histologic disease activity in addition to their relationship with long-term clinical outcomes. We assessed intraparticipant variability in infliximab concentrations between adjacent intestinal samples and the correlation between disease activity and tumor necrosis factor-α (TNF-α). METHODS: A prospective cohort study was conducted in participants with UC receiving infliximab...
May 8, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38717544/neuroendocrine-tumors-of-unknown-primary-in-the-setting-of-cytoreductive-hepatectomy
#16
JOURNAL ARTICLE
Markus Ammann, Hallbera Gudmundsdottir, Hubert Hackl, Stella K Adjei Antwi, Jonas Santol, Elizabeth B Habermann, Cornelius A Thiels, Susanne G Warner, Mark J Truty, Michael L Kendrick, Rory L Smoot, David M Nagorney, Sean P Cleary, Thorvardur R Halfdanarson, Patrick P Starlinger
BACKGROUND: Surgical cytoreduction for neuroendocrine tumor liver metastasis (NETLM) consistently shows positive long-term outcomes. Despite reservations in guidelines for surgery when the primary tumor is unidentified (UP-NET), this study compared the surgical and oncologic long-term outcomes between patients with these rare cases undergoing cytoreductive surgery and patients who had liver resection for known primaries. METHODS: The study identified 32 unknown primary liver metastases (UP-NETLM) in 522 retrospectively evaluated patients who underwent resection of well-differentiated NETLM between January 2000 and December 2020...
May 8, 2024: Annals of Surgical Oncology
https://read.qxmd.com/read/38717494/mirna-192-5p-targeted-activated-leukocyte-cell-adhesion-molecule-improved-inflammatory-injury-of-neonatal-necrotizing-enterocolitis
#17
JOURNAL ARTICLE
Zhenfei Wu, You Tian, Chen Wang, Jie Zhang, Jinhan Lin
BACKGROUND: Neonatal necrotizing enterocolitis (NEC) is a common gastrointestinal emergency in neonates. MiRNA-192-5p was found associated with ulcerative colitis (UC) progression, also with aberrant expression in intestinal cancer tissue. However, the effects of miRNA-192-5p on NEC have not been reported. METHODS: Based on the bioinformatics analysis of the GEO dataset, miR-192-5p was identified as the differentially expressed miRNA in NEC, and activated leukocyte cell adhesion molecule (ALCAM) was predicted as its target...
May 8, 2024: Pediatric Surgery International
https://read.qxmd.com/read/38716231/case-report-small-bowel-obstruction-secondary-to-congenital-transmesenteric-internal-hernia-in-a-cat
#18
Min-Hee Kang, Young-Chil Kang, Jun-Won Yoon, Hee-Myung Park
An 8-month-old castrated male British Shorthair cat presented with acute anorexia and vomiting. The overall clinical presentation included generalized depression. Physical examination revealed palpable abdominal mass, thus foreign body or intussusception was suspected. Abdominal radiographs showed segmental dilation of small intestine and ultrasonography revealed target lesion with dilated small bowel loops and disrupted normal wall layering, suggestive of intussusception. Exploratory laparotomy confirmed congenital mesenteric defects associated with small intestinal obstruction...
2024: Frontiers in Veterinary Science
https://read.qxmd.com/read/38716135/a-case-report-of-roundworms-causing-intestinal-obstruction-in-a-child
#19
Tushar Krishnaraju, Suvendu Sekhar Jena, Amitabh Yadav, Samiran Nundy
Background . Soil-transmitted helminth (STH) infections are a common global health issue that affects underprivileged communities without adequate access to clean drinking water, sanitation, and hygiene. Ascaris lumbricoides is the main species that infects humans. Among varied presentations, intestinal obstruction is common among children. Early detection of intestinal obstruction due to STH is critical to prevent severe complications. Here, we present the case of a 10-year-old child with acute intestinal obstruction due to roundworms...
2024: Case Reports in Surgery
https://read.qxmd.com/read/38714637/rare-recurrence-pattern-after-complete-response-to-chemotherapy-in-a-patient-with-rectal-cancer-a-case-report
#20
JOURNAL ARTICLE
Masatoshi Nomura, Mitsuyoshi Tei, Takayoshi Goto, Masataka Hirano, Kentaro Nishida, Soichiro Mori, Yukihiro Yoshikawa, Koki Tamai, Takuya Hamakawa, Daisuke Takiuchi, Masanori Tsujie, Yusuke Akamaru
BACKGROUND: Colorectal cancer (CRC) often metastasizes to the liver, lungs, lymph nodes, and peritoneum but rarely to the bladder, small intestine, and skin. We here report the rare metastasis of anal cancer in the left bladder wall, followed by metastases to the small intestine and skin, after abdominoperineal resection and left lateral lymph node dissection with chemotherapy in a patient with clinician Stage IVa disease. CASE PRESENTATION: A 66-year-old man presented with 1-month history of bloody stool and anal pain and diagnosed with clinical Stage IVa anal cancer with lymph node and liver metastases (cT3, N3 [#263L], M1a [H1])...
May 8, 2024: Surgical Case Reports
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