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https://www.readbyqxmd.com/read/28918603/tumor-markers-of-uterine-cervical-cancer-a-new-scenario-to-guide-surgical-practice
#1
REVIEW
Gaetano Valenti, Salvatore Giovanni Vitale, Alessandro Tropea, Antonio Biondi, Antonio Simone Laganà
Since the introduction of Pap smear screening, the incidence and mortality of cervical cancer (CC) have been reduced drastically in USA and in other western states. Nevertheless, CC still remains the main cause of death from gynecological cancer in developing countries where screening programs are scant or inexistent. This evidence highlights the efficacy of screening, and the wide use of Human Papilloma Viruses (HPV) vaccines in developed countries. More and more people are, consequentially, undergoing a screening procedure, usually combined with HPV DNA test, increasing the early diagnosis of intraepithelial HPV-related lesions...
September 16, 2017: Updates in Surgery
https://www.readbyqxmd.com/read/28918595/successful-pregnancy-in-a-ckd-patient-on-a-low-protein-supplemented-diet-an-opportunity-to-reflect-on-ckd-and-pregnancy-in-mexico-an-emerging-country
#2
Julia Nava, Silvia Moran, Veronica Figueroa, Adriana Salinas, Margy Lopez, Rocio Urbina, Abril Gutierrez, Jose Luis Lujan, Alejandra Orozco, Rafael Montufar, Giorgina B Piccoli
Pregnancy is probably the most important challenge in young women with chronic kidney disease (CKD). The challenge is greater in developing countries, in which access to dialysis is uneven, and prenatal care for CKD patients is not uniformly available. This case report summarizes some of the challenges faced by pregnant CKD women in a developing country. A 35-year-old woman, affected by an undiagnosed kidney disease, experienced preeclampsia at 24 years of age, and started dialysis in emergency at age 31 in the context of severe preeclampsia in her second pregnancy...
September 16, 2017: Journal of Nephrology
https://www.readbyqxmd.com/read/28918539/accelerating-vaccine-development-during-the-2013-2016-west-african-ebola-virus-disease-outbreak
#3
Elizabeth S Higgs, Sheri A Dubey, Beth A G Coller, Jakub K Simon, Laura Bollinger, Robert A Sorenson, Barthalomew Wilson, Martha C Nason, Lisa E Hensley
The Ebola virus disease outbreak that began in Western Africa in December 2013 was unprecedented in both scope and spread, and the global response was slower and less coherent than was optimal given the scale and pace of the epidemic. Past experience with limited localized outbreaks, lack of licensed medical countermeasures, reluctance by first responders to direct scarce resources to clinical research, community resistance to outside interventions, and lack of local infrastructure were among the factors delaying clinical research during the outbreak...
September 17, 2017: Current Topics in Microbiology and Immunology
https://www.readbyqxmd.com/read/28918502/the-refinement-glossary-of-terms-an-international-terminology-for-mental-health-systems-assessment
#4
Ilaria Montagni, Luis Salvador-Carulla, David Mcdaid, Christa Straßmayr, Florian Endel, Petri Näätänen, Jorid Kalseth, Birgitte Kalseth, Tihana Matosevic, Valeria Donisi, Karine Chevreul, Amélie Prigent, Raluca Sfectu, Carmen Pauna, Mencia R Gutiérrez-Colosia, Francesco Amaddeo, Heinz Katschnig
Comparing mental health systems across countries is difficult because of the lack of an agreed upon terminology covering services and related financing issues. Within the European Union project REFINEMENT, international mental health care experts applied an innovative mixed "top-down" and "bottom-up" approach following a multistep design thinking strategy to compile a glossary on mental health systems, using local services as pilots. The final REFINEMENT glossary consisted of 432 terms related to service provision, service utilisation, quality of care and financing...
September 16, 2017: Administration and Policy in Mental Health
https://www.readbyqxmd.com/read/28918448/a-systematic-review-of-cost-effectiveness-analysis-of-screening-interventions-for-assessing-the-risk-of-venous-thromboembolism-in-women-considering-combined-oral-contraceptives
#5
REVIEW
Zanfina Ademi, C Simone Sutherland, Joris Van Stiphout, Jöelle Michaud, Goranka Tanackovic, Matthias Schwenkglenks
Use of combined oral contraceptives (COCs) by women increases the risk of venous thromboembolism (VTE), which can have a major impact on an individuals' quality of life. VTE is also associated with an increase in healthcare costs. Our aim was to systematically review cost-effectiveness analyses (CEAs) considering any screening for risk of VTE in women using COCs. The quality of reporting in each study was assessed, a summary of results was prepared, and the key drivers of cost effectiveness in each of the eligible CEAs were identified...
September 16, 2017: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/28918369/the-development-of-biodiversity-conservation-measures-in-china-s-hydro-projects-a-review
#6
REVIEW
Ruiqiao Bai, Xuehua Liu, Xiaofei Liu, Lanmei Liu, Jianping Wang, Sihui Liao, Annah Zhu, Zhouyuan Li
The hydropower capacity of China ranks first in the world and accounts for approximately 20% of the total energy production in the country. While hydropower has substantially contributed to meeting China's renewable energy targets and providing clean energy to rural areas, the development of hydropower in China has been met with significant controversy. Ecologically, hydro projects alter the landscape, with potential impacts to the country's aquatic biodiversity. Over the past four decades in China, various mainstream opinions and misunderstandings have been presented concerning how to alleviate the negative impacts of hydro projects on aquatic ecosystems...
September 14, 2017: Environment International
https://www.readbyqxmd.com/read/28918346/anaerobic-digestion-for-bioenergy-production-global-status-environmental-and-techno-economic-implications-and-government-policies
#7
REVIEW
Juliana Vasco-Correa, Sami Khanal, Ashish Manandhar, Ajay Shah
Anaerobic digestion (AD) is a mature technology that can transform organic matter into a bioenergy source - biogas (composed mainly of methane and carbon dioxide), while stabilizing waste. AD implementation around the world varies significantly, from small-scale household digesters in developing countries to large farm-scale or centralized digesters in developed countries. These differences in the implementation of AD technology are due to a complex set of conditions, including economic and environmental implications of the AD technology, and stimulus provided by a variety of polices and incentives related to agricultural systems, waste management, and renewable energy production...
September 5, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28918322/time-for-tiger-to-roar-technology-informatics-guiding-education-reform
#8
EDITORIAL
Siobhan O'Connor, Ursula Hubner, Toria Shaw, Rachelle Blake, Marion Ball
Information Technology (IT) continues to evolve and develop with electronic devices and systems becoming integral to healthcare in every country. This has led to an urgent need for all professions working in healthcare to be knowledgeable and skilled in informatics. The Technology Informatics Guiding Education Reform (TIGER) Initiative was established in 2006 in the United States to develop key areas of informatics in nursing. One of these was to integrate informatics competencies into nursing curricula and life-long learning...
August 19, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28918144/short-communication-molecular-epidemiology-of-streptococcus-agalactiae-differs-between-countries
#9
J Reyes, M Chaffer, Juan Carlos Rodriguez-Lecompte, Javier Sánchez, Ruth N Zadoks, Natasha Robinson, Ximena Cardona, N Ramírez, G P Keefe
Group B Streptococcus or Streptococcus agalactiae continue to be challenging for milk quality programs in countries with emerging dairy industries, such as Colombia, where high prevalence has been reported. Molecular typing of isolates is needed to understand the variability and epidemiology of this pathogen and to develop effective control and eradication programs. We characterized the molecular profile of Strep. agalactiae isolated from cows with subclinical mastitis in 21 Colombian dairy herds and measured diversity within and between herds using multilocus sequence typing...
September 13, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28918033/six-highly-conserved-targets-of-rnai-revealed-in-hiv-1-infected-patients-from-russia-are-also-present-in-many-hiv-1-strains-worldwide
#10
Olga V Kretova, Daria M Fedoseeva, Maria A Gorbacheva, Natalya M Gashnikova, Maria P Gashnikova, Nataliya V Melnikova, Vladimir R Chechetkin, Yuri V Kravatsky, Nickolai A Tchurikov
RNAi has been suggested for use in gene therapy of HIV/AIDS, but the main problem is that HIV-1 is highly variable and could escape attack from the small interfering RNAs (siRNAs) due to even single nucleotide substitutions in the potential targets. To exhaustively check the variability in selected RNA targets of HIV-1, we used ultra-deep sequencing of six regions of HIV-1 from the plasma of two independent cohorts of patients from Russia. Six RNAi targets were found that are invariable in 82%-97% of viruses in both cohorts and are located inside the domains specifying reverse transcriptase (RT), integrase, vpu, gp120, and p17...
September 15, 2017: Molecular Therapy. Nucleic Acids
https://www.readbyqxmd.com/read/28917750/portable-near-infrared-spectroscopy-applied-to-fuel-quality-control
#11
Radigya M Correia, Eloilson Domingos, Vagne M Cáo, Brenda R F Araujo, Sthefany Sena, Layla U Pinheiro, André M Fontes, Luiz Felipe M Aquino, Ernesto C Ferreira, Paulo R Filgueiras, Wanderson Romão
Fuel quality control has gained interest in many countries owing to the potential damage of low-quality fuel to engines, the environment, and economy. Thus, the application of analytical techniques to verify quality control of fuels has become crucial. The portable micro-spectrometer in the near infrared region (microNIR) has gained credibility as a successful analytical technique in several quality control sectors. The possibility of real-time analysis using a nondestructive and reliable method is the main advantage of this methodology...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28917500/economic-evaluation-of-childhood-epilepsy-in-a-resource-challenged-setting-a-preliminary-survey
#12
Aliyu Ibrahim, Umar Isa Umar, Umar Musa Usman, Lukman Femi Owolabi
BACKGROUND: Considerable disease variability exists between patients with epilepsy, and the societal costs for epilepsy care are overall high, because of high frequency in the general population especially in children from developing countries. MATERIALS AND METHODS: A cross-sectional study where children with established diagnosis of epilepsy were interviewed using a semi-structured questionnaire. Prevalence-based costs were stratified by patients' sociodemographic characteristics and socioeconomic scores (SES)...
September 13, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28917326/serum-levels-of-cytokines-in-water-buffaloes-experimentally-infected-with-fasciola-gigantica
#13
Fu-Kai Zhang, Ai-Jiang Guo, Jun-Ling Hou, Miao-Miao Sun, Zhao-An Sheng, Xiao-Xuan Zhang, Wei-Yi Huang, Hany M Elsheikha, Xing-Quan Zhu
Fasciola gigantica infection in water buffaloes causes significant economic losses especially in developing countries. Although modulation of the host immune response by cytokine neutralization or vaccination is a promising approach to control infection with this parasite, our understanding of cytokine's dynamic during F. gigantica infection is limited. To address this, we quantified the levels of serum cytokines produced in water buffaloes following experimental infection with F. gigantica. Five buffaloes were infected via oral gavage with 500 viable F...
September 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28917222/validation-of-summer-and-winter-elisa-measurements-of-serum-25-hydroxyvitamin-d-concentrations-in-mongolia
#14
Sabri Bromage, Daria Tselmen, Gary Bradwin, Michael F Holick, Davaasaambuu Ganmaa
BACKGROUND AND OBJECTIVES: Assay cost, quality, and availability pose challenges for vitamin D surveys in limited resource settings. This study aimed to validate an inexpensive vitamin D assay (ELISA) under real-world conditions in Mongolia, the northernmost developing country, to characterize the assay's usefulness and inform the design of epidemiologic studies in similar regions. METHODS AND STUDY DESIGN: We collected paired summer and winter serum samples from 120 men and women (aged 20-57 years) in urban and rural Mongolia, analyzed each sample for 25(OH)D concentration using both Immunodiagnostic Systems ELISA and DiaSorin LIAISON 25(OH)D TOTAL, and compared the assays using multiple statistics...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28917219/reuma-pt-contribution-to-the-knowledge-of-immune-mediated-systemic-rheumatic-diseases
#15
Maria José Santos, Helena Canhão, Ana Filipa Mourão, Filipa Oliveira Ramos, Cristina Ponte, Cátia Duarte, Anabela Barcelos, Fernando Martins, José António Melo Gomes
Patient registries are key instruments aimed at a better understanding of the natural history of diseases, at assessing the effectiveness of therapeutic interventions, as well as identifying rare events or outcomes that are not captured in clinical trials. However, the potential of registries goes far beyond these aspects. For example, registries promote the standardization of clinical practice, can also provide information on domains that are not routinely collected in clinical practice and can support decision-making...
September 14, 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28917171/ambient-air-pollution-and-daily-hospital-admissions-for-mental-disorders-in-shanghai-china
#16
Chen Chen, Cong Liu, Renjie Chen, Weibing Wang, Weihua Li, Haidong Kan, Chaowei Fu
Few studies have investigated the associations between ambient air pollution and mental disorders (MDs), especially in developing countries. We conducted a time-series study to explore the associations between six criteria air pollutants and daily hospital admissions for MDs in Shanghai, China, from 2013 to 2015. The MDs data were derived from the Shanghai Health Insurance System. We used over-dispersed, generalized additive models to estimate the associations after controlling for time trend, weather conditions, day of the week, and holidays...
September 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28916563/incidence-of-retinopathy-of-prematurity-rop-and-rop-treatment-in-switzerland-2006-2015-a-population-based-analysis
#17
Roland Gerull, Viviane Brauer, Dirk Bassler, Bernard Laubscher, Riccardo E Pfister, Mathias Nelle, Béatrice Müller, Christina Gerth-Kahlert, Mark Adams
BACKGROUND: Retinopathy of prematurity (ROP) is a severe complication of preterm birth and can lead to severe visual impairment or even blindness if untreated. The incidence of ROP requiring treatment is increasing in some developed countries in conjunction with higher survival rates at the lower end of gestational age (GA). MATERIAL AND METHODS: The incidence of ROP and severe ROP (sROP) requiring treatment in Switzerland was analysed using the SwissNeoNet registry...
September 15, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28916499/-re-programming-of-subtype-specific-cardiomyocytes
#18
Frauke Hausburg, Julia Jeannine Jung, Matti Hoch, Markus Wolfien, Arash Yavari, Christian Rimmbach, Robert David
Adult cardiomyocytes (CMs) possess a highly restricted intrinsic regenerative potential -a major barrier to the effective treatment of a range of chronic degenerative cardiac disorders characterised by cellular loss and/or irreversible dysfunction and which underlies the majority of deaths in developed countries. Both stem cell programming and direct cell reprogramming hold promise as novel, potentially curative approaches to address this therapeutic challenge. The advent of induced pluripotent stem cells (iPSCs) has introduced a second pluripotent stem cell source besides embryonic stem cells (ESCs), enabling even autologous cardiomyocyte production...
September 12, 2017: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/28916469/activity-changes-in-the-left-superior-temporal-sulcus-reflect-the-effects-of-childcare-training-on-young-female-students-perceptions-of-infants-negative-facial-expressions
#19
Ayahito Ito, Katsuko Niwano, Motoko Tanabe, Yosuke Sato, Toshikatsu Fujii
In many developed countries, the number of infants who experience non-parent childcare is increasing, and the role of preschool teachers is becoming more important. However, little attention has been paid to the effects of childcare training on students who are studying to become preschool teachers. We used functional magnetic resonance imaging (fMRI) to investigate whether and how childcare training affects brain responses to infants' facial expressions among young females studying to become preschool teachers...
September 12, 2017: Neuroscience Research
https://www.readbyqxmd.com/read/28916417/in-hospital-clinical-outcomes-after-upper-gastrointestinal-surgery-data-from-an-international-observational-study
#20
T Szakmany, J Ditai, M Kirov, D Protsenko, B Osinaike, A Venara, N Demartines, M Hubner, R M Pearse, J R Prowle
AIMS: Previous research suggests that patients undergoing upper gastrointestinal surgery are at high risk of poor postoperative outcomes. The aim of our study was to describe patient outcomes after elective upper gastrointestinal surgery at a global level. METHODS: Prospective analysis of data collected during an international seven-day cohort study of 474 hospitals in 27 countries. Patients undergoing elective upper gastrointestinal surgery were recruited. Outcome measures were in-hospital complications and mortality at 30-days...
August 18, 2017: European Journal of Surgical Oncology
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